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List of works by Tomislav Rovis

A Late Stage Strategy for the Functionalization of Triazolium-based NHC catalysts

scientific article published on January 2014

A Mild Hydroaminoalkylation of Conjugated Dienes Using a Unified Cobalt and Photoredox Catalytic System

scientific article published on 19 October 2017

A Rh(III)-Catalyzed Formal [4+1] Approach to Pyrrolidines from Unactivated Terminal Alkenes and Nitrene Sources

scientific article published on 05 August 2019

A Sakurai−Prins−Ritter Sequence for the Three-Component Diastereoselective Synthesis of 4-Amino Tetrahydropyrans

scientific article published in 2006

A catalytic asymmetric synthesis of polysubstituted piperidines using a rhodium(I)-catalyzed [2+2+2] cycloaddition employing a cleavable tether

scientific article published on 19 April 2013

A coupling of benzamides and donor/acceptor diazo compounds to form γ-lactams via Rh(III)-catalyzed C-H activation

scientific article

A diastereoselective ring contraction of 1,3-dioxepins to 2,3,4-trisubstituted and tetrasubstituted tetrahydrofurans

scientific article

A highly enantioselective catalytic intramolecular Stetter reaction

scientific article published in September 2002

A mild and efficient catalytic alkylative monofunctionalization of cyclic anhydrides

scientific article published in January 2002

A photoisomerization-coupled asymmetric Stetter reaction: application to the total synthesis of three diastereomers of (-)-cephalimysin A.

scientific article published on April 2013

A site-selective amination catalyst discriminates between nearly identical C-H bonds of unsymmetrical disubstituted alkenes

scientific article published on 15 June 2020

Amide-directed photoredox-catalysed C-C bond formation at unactivated sp3 C-H bonds

scientific article published on 12 October 2016

An Improved Catalyst Architecture for Rhodium (III) Catalyzed C-H Activation and its Application to Pyridone Synthesis

scientific article published in August 2011

An asymmetric synthesis of 1,2,4-trioxane anticancer agents via desymmetrization of peroxyquinols through a Brønsted acid catalysis cascade

scientific article

An efficient synthesis of achiral and chiral 1,2,4-triazolium salts: bench stable precursors for N-heterocyclic carbenes

scientific article published on July 2005

Asymmetric N-Heterocyclic Carbene (NHC) Catalyzed Acyl Anion Reactivity

scientific article published on January 2011

Asymmetric N-heterocyclic carbene catalyzed addition of enals to nitroalkenes: controlling stereochemistry via the homoenolate reactivity pathway to access δ-lactams

scientific article published on 28 May 2013

Asymmetric NHC-catalyzed synthesis of α-fluoroamides from readily accessible α-fluoroenals

scientific article published on April 2013

Asymmetric synthesis of bicyclic amidines via rhodium-catalyzed [2+2+2] cycloaddition of carbodiimides

scientific article published on 27 February 2008

Asymmetric synthesis of functionalized cyclopentanones via a multicatalytic secondary amine/N-heterocyclic carbene catalyzed cascade sequence

scientific article published on September 2009

Asymmetric synthesis of hydrobenzofuranones via desymmetrization of cyclohexadienones using the intramolecular Stetter reaction

scientific article published on March 2006

Asymmetric δ-Lactam Synthesis with a Monomeric Streptavidin Artificial Metalloenzyme

scientific article published on 13 March 2019

Beyond Reppe: building substituted arenes by [2+2+2] cycloadditions of alkynes

scientific article published on January 2009

Biotinylated Rh(III) complexes in engineered streptavidin for accelerated asymmetric C-H activation

scientific article published on October 2012

Carbene Catalysts ⬇️

scientific article published on January 1, 2010

Catalytic asymmetric cross-aza-benzoin reactions of aliphatic aldehydes with N-Boc-protected imines

scientific article published on 4 May 2012

Catalytic asymmetric intermolecular Stetter reaction of enals with nitroalkenes: enhancement of catalytic efficiency through bifunctional additives

scientific article published on 16 June 2011

Catalytic asymmetric intermolecular Stetter reaction of glyoxamides with alkylidenemalonates

scientific article published on 4 October 2008

Catalytic asymmetric intermolecular Stetter reactions of enolizable aldehydes with nitrostyrenes: computational study provides insight into the success of the catalyst

scientific article

Catalytic asymmetric intermolecular stetter reaction of heterocyclic aldehydes with nitroalkenes: backbone fluorination improves selectivity

scientific article

Catalytic asymmetric stetter reaction onto vinylphosphine oxides and vinylphosphonates

scientific article published on 13 June 2008

Catalytic asymmetric α-acylation of tertiary amines mediated by a dual catalysis mode: N-heterocyclic carbene and photoredox catalysis

scientific article

Catalytic, asymmetric indolizidinone aza-quaternary stereocenter synthesis: expedient synthesis of the cylindricine alkaloid core

scientific article published on 30 April 2013

Complementary Strategies for Directed C(sp3 )-H Functionalization: A Comparison of Transition-Metal-Catalyzed Activation, Hydrogen Atom Transfer, and Carbene/Nitrene Transfer

scientific article

Correction to "Correlating Reactivity and Selectivity to Cyclopentadienyl Ligand Properties in Rh(III)-Catalyzed C-H Activation Reactions: An Experimental and Computational Study"

scientific article published on 09 April 2020

Correction to "Oxidatively Initiated NHC-Catalyzed Enantioselective Synthesis of 3,4-Disubstituted Cyclopentanones from Enals".

scientific article

Correctionto “Rh(III)-Catalyzed Cyclopropanation Initiated by C–H Activation: Ligand Development Enables a Diastereoselective [2 + 1] Annulation of N-Enoxyphthalimides and Alkenes”.

scientific article published on 23 September 2014

Correlating Reactivity and Selectivity to Cyclopentadienyl Ligand Properties in Rh(III)-Catalyzed C-H Activation Reactions: An Experimental and Computational Study

scientific article published on 6 January 2017

Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19

scientific article published on 07 April 2022

Direct Regio- and Diastereoselective Synthesis of δ-Lactams from Acrylamides and Unactivated Alkenes Initiated by RhIII -Catalyzed C-H Activation

scientific article published on 11 February 2020

Direct α-alkylation of primary aliphatic amines enabled by CO and electrostatics

scientific article published on 30 July 2018

Directed γ-C(sp3)-H Alkylation of Carboxylic Acid Derivatives through Visible Light Photoredox Catalysis

scientific article published on 12 October 2017

Dual Nickel- and Photoredox-Catalyzed Enantioselective Desymmetrization of Cyclic meso-Anhydrides

scientific article published on 23 February 2017

Electrochemical Synthesis of Hindered Primary and Secondary Amines via Proton-Coupled Electron Transfer

scientific article published on 18 December 2019

Electronic and Steric Tuning of a Prototypical Piano Stool Complex: Rh(III) Catalysis for C-H Functionalization

scientific article

Enamine/Carbene Cascade Catalysis in the Diastereo- and Enantioselective Synthesis of Functionalized Cyclopentanones

scientific article published on September 2011

Enantio- and diastereoselective intermolecular Stetter reaction of glyoxamide and alkylidene ketoamides

scientific article published on July 2009

Enantioselective N-heterocyclic carbene-catalyzed nucleophilic dearomatization of alkyl pyridiniums

scientific article published on 3 August 2017

Enantioselective N-heterocyclic carbene-catalyzed β-hydroxylation of enals using nitroarenes: an atom transfer reaction that proceeds via single electron transfer

scientific article published on 10 October 2014

Enantioselective Rhodium-Catalyzed Alkylative Desymmetrization of 3,5-Dimethylglutaric Anhydride

scholarly article by Tomislav Rovis & Matthew J. Cook published 12 December 2008 in Synthesis

Enantioselective Rhodium-Catalyzed [2 + 2 + 2] Cycloadditions of Terminal Alkynes and Alkenyl Isocyanates: Mechanistic Insights Lead to a Unified Model that Rationalizes Product Selectivity

scientific article

Enantioselective Rhodium-Catalyzed [2+2+2] Cycloaddition of Pentenyl Isocyanate and 4-Ethynylanisole: Preparation and Use of Taddolpyrrolidine Phosphoramidite

scientific article

Enantioselective Synthesis of Hydrobenzofuranones Using an Asymmetric Desymmetrizing Intramolecular Stetter Reaction of Cyclohexadienones

scientific article published on January 2007

Enantioselective Synthesis of the Tricyclic Core of FR901483 Featuring a Rh-Catalyzed [2+2+2] Cycloaddition

scientific article published on January 2013

Enantioselective cross-coupling of anhydrides with organozinc reagents: the controlled formation of carbon-carbon bonds through the nucleophilic interception of metalacycles

scientific article published on 31 January 2008

Enantioselective protonation of catalytically generated chiral enolates as an approach to the synthesis of alpha-chloroesters

scientific article published in November 2005

Enantioselective rhodium-catalyzed [4+2+2] cycloaddition of dienyl isocyanates for the synthesis of bicyclic azocine rings

scientific article published on September 2009

Enantioselective rhodium-catalyzed [4+2] cycloaddition of α,β-unsaturated imines and isocyanates

scientific article published on 14 March 2011

Enantioselective rhodium-catalyzed isomerization of 4-iminocrotonates: asymmetric synthesis of a unique chiral synthon

scientific article published on 12 January 2015

Enantioselective synthesis of indolizidines bearing quaternary substituted stereocenters via rhodium-catalyzed [2+2+2] cycloaddition of alkenyl isocyanates and terminal alkynes

scientific article published on 20 February 2008

Enantioselective synthesis of quaternary stereocenters via a catalytic asymmetric Stetter reaction

scientific article

Excess substrate is a spectator ligand in a rhodium-catalyzed asymmetric [2 + 2 + 2] cycloaddition of alkenyl isocyanates with tolanes

scientific article published on November 2009

Expedient Access to 2,3-Dihydropyridines from Unsaturated Oximes by Rh(III)-Catalyzed C-H Activation

scientific article published on 08 July 2015

Experimental and Computational Gas Phase Acidities of Conjugate Acids of Triazolylidene Carbenes: Rationalizing Subtle Electronic Effects.

scientific article published on 17 October 2017

Exploiting Acyl and Enol Azolium Intermediates via NHeterocyclic Carbene Catalyzed Reactions of Alpha-Reducible Aldehydes

scientific article published on 19 April 2012

Generation of Phosphoranyl Radicals via Photoredox Catalysis Enables Voltage-Independent Activation of Strong C-O Bonds

scientific article published on 18 October 2018

Heptamethylindenyl (Ind*) enables diastereoselective benzamidation of cyclopropenes via Rh(iii)-catalyzed C-H activation

scientific article published on 23 September 2016

Influence of Electronic Effects on the Reactivity of Triazolylidene-Boryl Radicals: Consequences for the use of N-Heterocyclic Carbene Boranes in Organic and Polymer Synthesis

scientific article published on 3 August 2015

Ir(III)-Catalyzed Carbocarbation of Alkynes through Undirected Double C-H Bond Activation of Anisoles

scientific article published on 11 April 2018

Ir-Catalyzed Intermolecular Branch-Selective Allylic C-H Amidation of Unactivated Terminal Olefins

scientific article published on 04 February 2019

Isolable analogues of the Breslow intermediate derived from chiral triazolylidene carbenes

scientific article published on 28 March 2012

Ligand Controlled Ir-Catalyzed Regiodivergent Oxyamination of Unactivated Alkenes

scientific article published on 16 July 2019

Ligand Design for Rh(III)-Catalyzed C-H Activation: An Unsymmetrical Cyclopentadienyl Enables a Regioselective Synthesis of Dihydroisoquinolones

scientific article published on January 2015

Ligand differentiated complementary Rh-catalyst systems for the enantioselective desymmetrization of meso-cyclic anhydrides

Mechanistic investigation of the enantioselective intramolecular stetter reaction: proton transfer is the first irreversible step

scientific article

More than bystanders: the effect of olefins on transition-metal-catalyzed cross-coupling reactions

scientific article published on January 2008

Multi-component cycloaddition approaches in the catalytic asymmetric synthesis of alkaloid targets

scientific article published on 15 September 2009

Multicatalytic, asymmetric Michael/Stetter reaction of salicylaldehydes and activated alkynes

scientific article

N-Heterocyclic Carbene and Chiral Brønsted Acid Cooperative Catalysis for a Highly Enantioselective [4+2] Annulation

scientific article published on 18 November 2016

N-Heterocyclic carbene catalyzed asymmetric hydration: direct synthesis of alpha-protio and alpha-deuterio alpha-chloro and alpha-fluoro carboxylic acids

scientific article published on March 2010

N-heterocyclic carbene and Brønsted acid cooperative catalysis: asymmetric synthesis of trans-γ-lactams

scientific article published on 25 July 2011

N-heterocyclic-carbene-catalyzed asymmetric oxidative hetero-Diels-Alder reactions with simple aliphatic aldehydes

scientific article published on 4 November 2012

Nickel-catalyzed reductive carboxylation of styrenes using CO2.

scientific article published on 17 October 2008

Novel actions of estrogen receptor-beta on anxiety-related behaviors

scientific journal article

Nucleophilic carbene and HOAt relay catalysis in an amide bond coupling: an orthogonal peptide bond forming reaction

scientific article published on 11 October 2007

Nucleophilic carbene catalyzed synthesis of 1,2 amino alcohols via azidation of epoxy aldehydes

scientific article published on December 2008

Organic chemistry: Natural polarity inverted

scientific article published in Nature

Organocatalytic Reactions Enabled by N-Heterocyclic Carbenes

scientific article

Organocatalytic hydroacylation of unactivated alkenes

scientific article published on 30 June 2011

Organometallic chemistry: C-H carboxylation takes gold

scientific article published on September 2010

Oxidatively Initiated NHC-Catalyzed Enantioselective Synthesis of 3,4-Disubstituted Cyclopentanones from Enals

scientific article published on 10 August 2015

Perfluorinated Taddol Phosphoramidite as an L,Z-Ligand on Rh(I) and Co(-I): Evidence for Bidentate Coordination via Metal-C6F5 Interaction

scientific article published on May 2013

Phosphoramidite-Rhodium Complexes as Catalysts for the Asymmetric [2+2+2] Cycloaddition of Alkenyl Isocyanates and Alkynes

scientific article published on July 2009

Photoredox-Catalyzed Deaminative Alkylation via C-N Bond Activation of Primary Amines

scientific article published on 15 October 2020

Photoredox-Catalyzed Site-Selective α-C(sp3 )-H Alkylation of Primary Amine Derivatives

scientific article published on 15 February 2019

Predictable and regioselective insertion of internal unsymmetrical alkynes in rhodium-catalyzed cycloadditions with alkenyl isocyanates

scientific article published on August 2009

Pyridine synthesis from oximes and alkynes via rhodium(III) catalysis: Cp* and Cp(t) provide complementary selectivity

scientific article published on 10 October 2011

Quantum mechanical investigation of the effect of catalyst fluorination in the intermolecular asymmetric Stetter reaction

scientific article

Rapid Construction of (-)-Paroxetine and (-)-Femoxetine via N-Heterocyclic Carbene Catalyzed Homoenolate Addition to Nitroalkenes

scientific article published on April 2014

Regiodivergent Iridium(III)-Catalyzed Diamination of Alkenyl Amides with Secondary Amines: Complementary Access to γ- or δ-Lactams.

scientific article published on 26 December 2017

Regioselective Alkylative Cross-Coupling of Remote Unactivated C(sp3)-H Bonds

scientific article published on 03 September 2019

Regioselective Lewis acid-mediated [1,3] rearrangement of allylvinyl ethers

scientific article published in May 2005

Regioselective rhodium-catalyzed intermolecular [2+2+2] cycloaddition of alkynes and isocyanates to form pyridones

scientific article published on June 2009

Rh(I)-bisphosphine-catalyzed asymmetric, intermolecular hydroheteroarylation of α-substituted acrylate derivatives

scientific article published on 29 December 2014

Rh(III)-Catalyzed C-H Activation-Initiated Directed Cyclopropanation of Allylic Alcohols

scientific article published on 18 April 2019

Rh(III)-catalyzed cyclopropanation initiated by C-H activation: ligand development enables a diastereoselective [2 + 1] annulation of N-enoxyphthalimides and alkenes

scientific article published on 5 August 2014

Rh(III)-catalyzed decarboxylative coupling of acrylic acids with unsaturated oxime esters: carboxylic acids serve as traceless activators

scientific article published on 10 February 2014

Rh(III)-catalyzed regioselective synthesis of pyridines from alkenes and α,β-unsaturated oxime esters

scientific article published on 18 December 2012

Rhodium(III)-Catalyzed Allylic C(sp(3))-H Activation of Alkenyl Sulfonamides: Unexpected Formation of Azabicycles

scientific article published on 11 September 2015

Rhodium(III)-Catalyzed C-H Activation Mediated Synthesis of Isoquinolones from Amides and Cyclopropenes

scientific article published on January 2013

Rhodium(III)-Catalyzed C-H Activation: An Oxidative Intramolecular Heck-Type Reaction Directed by a Carboxylic Acid

scientific article published on 15 June 2015

Rhodium(III)-catalyzed intramolecular hydroarylation, amidoarylation, and Heck-type reaction: three distinct pathways determined by an amide directing group

scientific article published on 8 November 2013

Rhodium(III)-catalyzed oxidative carbonylation of benzamides with carbon monoxide

scientific article published on 17 October 2011

Rhodium-catalysed syn-carboamination of alkenes via a transient directing group

scientific article published on 21 October 2015

Rhodium-catalyzed [2 + 2 + 2] cycloaddition of alkenyl isocyanates and alkynes

scientific article published in March 2006

Rhodium-catalyzed oxidative cycloaddition of benzamides and alkynes via C-H/N-H activation

scientific article published on August 2010

SNAr-Derived Decomposition By-products Involving Pentafluorophenyl Triazolium Carbenes

scientific article published on June 2013

Scope of the asymmetric intramolecular stetter reaction catalyzed by chiral nucleophilic triazolinylidene carbenes

scientific article

Stable Carbenes: From ‘Laboratory Curiosities' to Catalysis Mainstays

Stereodivergent Rhodium(III)-Catalyzed cis-Cyclopropanation Enabled by Multivariate Optimization

scientific article published on 23 July 2018

Stereoelectronic basis for the kinetic resolution of N-heterocycles with chiral acylating reagents

scientific article

Stereoretentive O-to-C rearrangement of vinyl acetals: solvent cage effects as a stereocontrol element

scientific article published in August 2002

Stereoselective Synthesis of Dioxolanes and Oxazolidines via a Desymmetrization Acetalization/Michael Cascade

scientific article published on March 2014

Surveying approaches to the formation of carbon-carbon bonds between a pyran and an adjacent ring

scientific article

Synthesis of Sterically Hindered Primary Amines by Concurrent Tandem Photoredox Catalysis

scientific article published on 06 January 2020

The Catalytic Asymmetric Intramolecular Stetter Reaction

scientific article

The [1, 3] O-to-C rearrangement: opportunities for stereoselective synthesis.

scientific article

Total synthesis of indolizidine alkaloid (-)-209D: overriding substrate bias in the asymmetric rhodium-catalyzed [2+2+2] cycloaddition

scientific article published on January 2009

Visible Light-Gated Cobalt Catalysis for a Spatially and Temporally Resolved [2+2+2] Cycloaddition.

scientific article

Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis

scientific article published on 22 April 2019

Zn-catalyzed enantio- and diastereoselective formal [4 + 2] cycloaddition involving two electron-deficient partners: asymmetric synthesis of piperidines from 1-azadienes and nitro-alkenes

scientific article published on 30 March 2015

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