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List of works by Joy M Burchell

A MUC1 tandem repeat reporter protein produced in CHO-K1 cells has sialylated core 1 O-glycans and becomes more densely glycosylated if coexpressed with polypeptide-GalNAc-T4 transferase.

scientific article published on 29 September 2004

A core protein epitope of the polymorphic epithelial mucin detected by the monoclonal antibody SM-3 is selectively exposed in a range of primary carcinomas

scientific article published on 01 June 1989

A short sequence, within the amino acid tandem repeat of a cancer-associated mucin, contains immunodominant epitopes

scientific article published on 01 October 1989

An alpha2,3 sialyltransferase (ST3Gal I) is elevated in primary breast carcinomas

scientific article published on 01 December 1999

Androgen-dependent synthesis of basic secretory proteins by the rat seminal vesicle ⬇️

scientific article published on August 15, 1976

Apoptosis of monocytes and the influence on yield of monocyte-derived dendritic cells.

scientific article published in November 2004

Autoantibodies to MUC1 glycopeptides cannot be used as a screening assay for early detection of breast, ovarian, lung or pancreatic cancer

scientific article published on 7 May 2013

Autoantibodies to aberrantly glycosylated MUC1 in early stage breast cancer are associated with a better prognosis.

scientific article published on 8 March 2011

Breast cancer associated transcriptional repressor PLU-1/JARID1B interacts directly with histone deacetylases

scientific article

Breast carcinoma cell lysate-pulsed dendritic cells cross-prime MUC1-specific CD8+ T cells identified by peptide-MHC-class-I tetramers.

scientific article

Cancer-associated autoantibodies to MUC1 and MUC4--a blinded case–control study of colorectal cancer in UK collaborative trial of ovarian cancer screening

scientific article published in May 2014

Cancer-associated hypersialylated MUC1 drives the differentiation of human monocytes into macrophages with a pathogenic phenotype

scientific article published on 04 November 2020

Characterisation and developmental expression of mouse Plu-1, a homologue of a human nuclear protein (PLU-1) which is specifically up-regulated in breast cancer

scientific article published in December 2002

Characterisation and developmental expression of mouse Plu-1, a homologue of a human nuclear protein (PLU-1) which is specifically up-regulated in breast cancer

scientific article

Characterizing the glycome of the mammalian immune system.

scientific article

Chemoenzymatically synthesized multimeric Tn/STn MUC1 glycopeptides elicit cancer-specific anti-MUC1 antibody responses and override tolerance.

scientific article published on 5 October 2005

Cloning of a Human UDP-N-Acetyl-α-d-Galactosamine:PolypeptideN-Acetylgalactosaminyltransferase That Complements Other GalNAc-Transferases in Complete O-Glycosylation of the MUC1 Tandem Repeat ⬇️

scientific article published on November 13, 1998

Comparison of O-linked carbohydrate chains in MUC-1 mucin from normal breast epithelial cell lines and breast carcinoma cell lines. Demonstration of simpler and fewer glycan chains in tumor cells.

scientific article

Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer

scientific article published on October 2013

Cyclooxygenase-2 Enzyme Induces the Expression of the -2,3-Sialyltransferase-3 (ST3Gal-I) in Breast Cancer ⬇️

scientific article published on December 28, 2012

Detection of the tumour-associated antigens recognized by the monoclonal antibodies HMFG-1 and 2 in serum from patients with breast cancer

scientific article published on 01 December 1984

Differential effect of interferon on DNA synthesis, 2-deoxyglucose uptake and ornithine decarboxylase activity in 3T3 cells stimulated by polypeptide growth factors and tumor promotors.

scientific article published on July 1980

Effective immunotherapy of cancer in MUC1-transgenic mice using clonal cytotoxic T lymphocytes directed against an immunodominant MUC1 epitope.

scientific article

Effects of Testosterone on Sequence Complexity of Polyadenylated RNA from Rat Seminal Vesicle ⬇️

scientific article published on November 15, 1978

Elevated IgG4 in patient circulation is associated with the risk of disease progression in melanoma

scientific article

Expression of fully and under-glycosylated forms of MUC1 mucin in gastric carcinoma.

scientific article published in August 1998

Expression of recombinant multi-coloured fluorescent antibodies in gor -/trxB- E. colicytoplasm ⬇️

scientific article published on November 30, 2011

Functional analysis of the transcription repressor PLU-1/JARID1B.

scientific article

Growth hormone is secreted by normal breast epithelium upon progesterone stimulation and increases proliferation of stem/progenitor cells

scientific article

HMFG1 antigen: a new marker for carcinomatous meningitis

scientific article published on 01 September 1989

Identification of a novel cancer-specific immunodominant glycopeptide epitope in the MUC1 tandem repeat

scientific article published on 18 October 2006

Identification of new cancer biomarkers based on aberrant mucin glycoforms by in situ proximity ligation.

scientific article published on July 2012

Immunisation with 'naïve' syngeneic dendritic cells protects mice from tumour challenge.

scientific article

Immunological analysis of mucin molecules expressed by normal and malignant mammary epithelial cells

scientific article published on 01 September 1987

Interactions between the breast cancer-associated MUC1 mucins and C-type lectin characterized by optical tweezers

scientific article

Interactions of mucins with the Tn or Sialyl Tn cancer antigens including MUC1 are due to GalNAc-GalNAc interactions.

scientific article

Intramuscular immunisation with MUC1 cDNA can protect C57 mice challenged with MUC1-expressing syngeneic mouse tumour cells

scientific article published on 01 March 1996

JARID1/KDM5 demethylases as cancer targets?

scientific article published on 28 November 2016

Lack of beta-casein production by human breast tumours revealed by monoclonal antibodies

scientific article published on 01 October 1987

Latest developments in MUC1 immunotherapy.

scientific article

MUC1 immunotherapy.

scientific article published on May 2010

Macrophage-tumour cell interactions: identification of MUC1 on breast cancer cells as a potential counter-receptor for the macrophage-restricted receptor, sialoadhesin

scientific article published on 01 October 1999

Mammosphere culture of metastatic breast cancer cells enriches for tumorigenic breast cancer cells

scientific article published on 9 June 2008

Mechanisms underlying aberrant glycosylation of MUC1 mucin in breast cancer cells.

scientific article

Microvesicle cargo of tumor-associated MUC1 to dendritic cells allows cross-presentation and specific carbohydrate processing.

scientific article published on 28 October 2013

Models of breast morphogenesis based on localization of stem cells in the developing mammary lobule

scientific article

Monoclonal antibodies to epithelium-specific components of the human milk fat globule membrane: Production and reaction with cells in culture

article

NMR-based determination of the binding epitope and conformational analysis of MUC-1 glycopeptides and peptides bound to the breast cancer-selective monoclonal antibody SM3.

scientific article published in March 2002

O-linked glycosylation in the mammary gland: changes that occur during malignancy.

scientific article

O-linked mucin-type glycosylation in breast cancer

article from 2018

PLU-1 nuclear protein, which is upregulated in breast cancer, shows restricted expression in normal human adult tissues: a new cancer/testis antigen?

scientific article

PLU-1, a transcriptional repressor and putative testis-cancer antigen, has a specific expression and localisation pattern during meiosis.

scientific article published on 10 September 2003

PLU-1/JARID1B/KDM5B is required for embryonic survival and contributes to cell proliferation in the mammary gland and in ER+ breast cancer cells ⬇️

scientific article published on February 28, 2011

Production and characterization of monoclonal antibodies to human casein. A monoclonal antibody that cross-reacts with casein and alpha-lactalbumin

scientific article published on 01 January 1985

Radioimmunoscintigraphy of ovarian tumors using a new monoclonal antibody, SM-3

scientific article published on 01 September 1990

Radioimmunoscintigraphy with technetium-99m-labelled monoclonal antibody, SM3, in gynaecological cancer

scientific article published on 01 June 1993

Repurposing tin mesoporphyrin as an immune checkpoint inhibitor shows therapeutic efficacy in preclinical models of cancer

scientific article published on 16 January 2018

Responses of human T cells to peptides flanking the tandem repeat and overlapping the signal sequence of MUC1

scientific article published on 01 July 2005

Selectin ligand sialyl-Lewis x antigen drives metastasis of hormone-dependent breast cancers.

scientific article

Selection of a Relevant In Vitro Blood-Brain Barrier Model to Investigate Pro-Metastatic Features of Human Breast Cancer Cell Lines

scientific article

Substrate specificities of three members of the human UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3

scientific article

Synergism of Toll-like receptor-induced interleukin-12p70 secretion by monocyte-derived dendritic cells is mediated through p38 MAPK and lowers the threshold of T-helper cell type 1 responses.

scientific article published in June 2007

T cells reactive with HLA‐A*0201 peptides from the histone demethylase JARID1B are found in the circulation of breast cancer patients ⬇️

scientific article published on February 11, 2011

Targeted macrophage cytotoxicity using a nonreplicative live vector expressing a tumor-specific single-chain variable region fragment

scientific article published on 01 July 2000

Targeting DNGR-1 (CLEC9A) with antibody/MUC1 peptide conjugates as a vaccine for carcinomas.

scientific article

Targeting of Tumor-Associated Glycoforms of MUC1 with CAR T Cells

scientific article published in November 2016

The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL.

scientific article published on 7 May 2015

The ST6GalNAc-I sialyltransferase localizes throughout the Golgi and is responsible for the synthesis of the tumor-associated sialyl-Tn O-glycan in human breast cancer.

scientific article

The mucin MUC1 modulates the tumor immunological microenvironment through engagement of the lectin Siglec-9.

scientific article published on 05 September 2016

The polymorphic epithelial mucin as a target for immunotherapy

scientific article published on 01 August 1993

The product of the human MUC1 gene when secreted by mouse cells transfected with the full-length cDNA lacks the cytoplasmic tail

scientific article published on 01 May 1992

The role of tumor-associated antigens in the biology and immunotherapy of breast cancer.

scientific article

Tn and STn are members of a family of carbohydrate tumor antigens that possess carbohydrate-carbohydrate interactions

scientific article published on 01 July 2018

Transforming growth factor-β1 is constitutively secreted by Chinese hamster ovary cells and is functional in human cells.

scientific article published on 9 June 2011

Tumor-Associated Tn-MUC1 Glycoform Is Internalized through the Macrophage Galactose-Type C-Type Lectin and Delivered to the HLA Class I and II Compartments in Dendritic Cells

scientific article published on 01 September 2007

Two E-selectin ligands, BST-2 and LGALS3BP, predict metastasis and poor survival of ER-negative breast cancer

scientific article

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