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List of works by Maria A Brehm

A biophysical view on von Willebrand factor activation.

scientific article published on 3 March 2017

Advancing multimer analysis of von Willebrand factor by single-molecule AFM imaging

scientific article published in PLoS ONE

Biophysical approaches promote advances in the understanding of von Willebrand factor processing and function.

scientific article

Efficacious inhibition of Importin α/β-mediated nuclear import of human inositol phosphate multikinase.

scientific article published on 12 March 2014

Enhanced Local Disorder in a Clinically Elusive von Willebrand Factor Provokes High-Affinity Platelet Clumping

scientific article

Force-sensitive autoinhibition of the von Willebrand factor is mediated by interdomain interactions

scientific article published on May 2015

Genetic and Functional Characterization of ADAMTS13 Variants in a Patient Cohort with Upshaw-Schulman Syndrome Investigated in Germany.

scientific article published on 19 March 2018

Human inositol 1,4,5-trisphosphate 3-kinase isoform B (IP3KB) is a nucleocytoplasmic shuttling protein specifically enriched at cortical actin filaments and at invaginations of the nuclear envelope.

scientific article published on 9 December 2010

Identification and characterization of the elusive mutation causing the historical von Willebrand Disease type IIC Miami

scientific article published on 25 June 2016

Mutual A domain interactions in the force sensing protein von Willebrand factor.

scientific article

Nucleocytoplasmic shuttling of human inositol phosphate multikinase is influenced by CK2 phosphorylation.

scientific article

Platelet-free shear flow assay facilitates analysis of shear-dependent functions of VWF and ADAMTS13.

scientific article published on 28 August 2014

Single molecule force spectroscopy data and BD- and MD simulations on the blood protein von Willebrand factor

scientific article

The inositol 5-phosphatase SHIP1 is a nucleo-cytoplasmic shuttling protein and enzymatically active in cell nuclei.

scientific article

The von Willebrand factor Tyr2561 allele is a gain-of-function variant and a risk factor for early myocardial infarction

scientific article published on 26 October 2018

Tumour cells can employ extracellular Ins(1,2,3,4,5,6)P(6) and multiple inositol-polyphosphate phosphatase 1 (MINPP1) dephosphorylation to improve their proliferation.

scientific article published in February 2013

Upshaw-Schulman syndrome-associated ADAMTS13 variants possess proteolytic activity at the surface of endothelial cells and in simulated circulation

scientific article published on 04 May 2020

Von Willebrand factor processing.

scientific article published on 21 November 2016

von Willebrand disease type 2A phenotypes IIC, IID and IIE: A day in the life of shear-stressed mutant von Willebrand factor

scientific article published on 06 March 2014

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