List of works by Chris Brightling

A case of cough, lymphocytic bronchoalveolitis and coeliac disease with improvement following a gluten free diet.

scientific article published on January 2002

A comparison of the validity of different diagnostic tests in adults with asthma.

scientific article

A method for quantitative analysis of regional lung ventilation using deformable image registration of CT and hybrid hyperpolarized gas/1H MRI.

scientific article published on 10 November 2014

A novel electrospun biphasic scaffold provides optimal three-dimensional topography for in vitro co-culture of airway epithelial and fibroblast cells.

scientific article

A polymorphism affecting MYB binding within the promoter of the PDCD4 gene is associated with severe asthma in children.

scientific article

ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle

scientific article

Activation of human lung mast cells by monomeric immunoglobulin E.

scientific article published in May 2005

Adapting the Electrospinning Process to Provide Three Unique Environments for a Tri-layered In Vitro Model of the Airway Wall

scientific article

Adenosine closes the K+ channel KCa3.1 in human lung mast cells and inhibits their migration via the adenosine A2A receptor.

scientific article published on June 2007

Advancing the management of Obstructive Airways Diseases through Translational Research.

scientific article published on 7 February 2018

Airway and peripheral urokinase plasminogen activator receptor is elevated in asthma, and identifies a severe, nonatopic subset of patients.

scientific article

Airway bacteria measured by quantitative polymerase chain reaction and culture in patients with stable COPD: relationship with neutrophilic airway inflammation, exacerbation frequency, and lung function.

scientific article published on 9 June 2015

Airway hyperresponsiveness is dissociated from airway wall structural remodeling.

scientific article published on 24 June 2008

Airway impedance entropy and exacerbations in severe asthma

scientific article published on 09 March 2012

Airway inflammation, airway responsiveness and cough before and after inhaled budesonide in patients with eosinophilic bronchitis.

scientific article

Airway smooth muscle NOX4 is upregulated and modulates ROS generation in COPD.

scientific article published on 19 July 2016

Alveolar nitric oxide in adults with asthma: evidence of distal lung inflammation in refractory asthma.

scientific article published in June 2005

American Thoracic Society/National Heart, Lung, and Blood Institute Asthma-Chronic Obstructive Pulmonary Disease Overlap Workshop Report

scientific article

An RGS4-mediated phenotypic switch of bronchial smooth muscle cells promotes fixed airway obstruction in asthma

scientific article

An empiric integrative approach to the management of cough: ACCP evidence-based clinical practice guidelines.

scientific article

Anti-IL-5 for Severe Asthma: Aiming High to Achieve Success

scientific article published on 01 October 2016

As strong as an OX or as weak as a kitten?

scientific article published in January 2014

Association between neutrophilic airway inflammation and airflow limitation in adults with asthma.

scientific article published on 9 October 2007

Association between pathogens detected using quantitative polymerase chain reaction with airway inflammation in COPD at stable state and exacerbations.

scientific article

Associations in asthma between quantitative computed tomography and bronchial biopsy-derived airway remodelling.

scientific article published on May 2017

Asthma

scientific article published on 19 December 2017

Asthma exacerbations and sputum eosinophil counts: a randomised controlled trial.

scientific article published in November 2002

Asthma exacerbations during pregnancy: A need for precision medicine

scientific article published on 16 December 2019

Asthma therapy and its effect on airway remodelling.

scientific article

Asthmatic airway smooth muscle CXCL10 production: mitogen-activated protein kinase JNK involvement.

scientific article

Azithromycin for Acute Exacerbations of Asthma : The AZALEA Randomized Clinical Trial

scientific article published on 19 September 2016

Benralizumab for chronic obstructive pulmonary disease and sputum eosinophilia: a randomised, double-blind, placebo-controlled, phase 2a study

scientific article published on 07 September 2014

Between-visit variability of small airway obstruction markers in patients with asthma

scientific article published on 06 March 2014

Big asthma data: getting bigger and more beautiful?

scientific article published on 29 December 2017

Biologic Drugs: A New Target Therapy in COPD?

scientific article published on 23 April 2018

Biological clustering supports both "Dutch" and "British" hypotheses of asthma and chronic obstructive pulmonary disease.

scientific article

Biological exacerbation clusters demonstrate asthma and chronic obstructive pulmonary disease overlap with distinct mediator and microbiome profiles.

scientific article published on 27 April 2018

Biomarkers predicting response to corticosteroid therapy in asthma.

scientific article

Biomarkers that predict and guide therapy for exacerbations of chronic obstructive pulmonary disease.

scientific article published on December 2013

Blood Eosinophils and Outcomes in Severe Hospitalized Exacerbations of COPD.

scientific article published on 3 February 2016

Blood and sputum eosinophils in COPD; relationship with bacterial load.

scientific article

Blood eosinophil count and airway epithelial transcriptome relationships in COPD versus asthma

scientific article published on 10 September 2019

Blood eosinophil guided prednisolone therapy for exacerbations of COPD: a further analysis.

scientific article published on 12 June 2014

Bronchoalveolar lavage invariant natural killer T cells are not increased in asthma

scientific article published in May 2007

Bronchoconstriction damages airway epithelia by crowding-induced excess cell extrusion

scientific article published on 04 April 2024

Building Bridges for Innovation in Ageing: Synergies between Action Groups of the EIP on AHA.

scientific article published on January 2017

CCL2 release by airway smooth muscle is increased in asthma and promotes fibrocyte migration.

scientific article

COPD: an inhaled corticosteroid-resistant, oral corticosteroid-responsive condition

scientific article published on 01 April 2006

CXCL8 histone H3 acetylation is dysfunctional in airway smooth muscle in asthma: regulation by BET

scientific article published on 20 February 2015

Characteristics and longitudinal progression of chronic obstructive pulmonary disease in GOLD B patients

scientific article published on 20 February 2017

Characterization of acinar airspace involvement in asthmatic patients by using inert gas washout and hyperpolarized (3)helium magnetic resonance.

scientific article published on August 2015

Chromosome 17q21 SNP and severe asthma.

scientific article

Chronic obstructive pulmonary disease phenotypes, biomarkers, and prognostic indicators

scientific article published on November 2016

Cigarette Smoke and the Induction of Urokinase Plasminogen Activator Receptor In Vivo: Selective Contribution of Isoforms to Bronchial Epithelial Phenotype

scientific article published on August 2015

Ciliary dysfunction and ultrastructural abnormalities are features of severe asthma.

scientific article published on 31 July 2010

Circulating fibrocytes: Will the real fibrocyte please stand up?

scientific article published on 22 March 2016

Clinical applications of induced sputum.

scientific article

Clinical significance of small airway obstruction markers in patients with asthma

scientific article published on 01 April 2014

Clinical trial research in focus: do trials prepare us to deliver precision medicine in those with severe asthma?

scientific article published on February 2017

Clinical, radiologic, and induced sputum features of chronic obstructive pulmonary disease in nonsmokers: a descriptive study.

scientific article

Cluster analysis and clinical asthma phenotypes.

scientific article published on 14 May 2008

Comorbidity in severe asthma requiring systemic corticosteroid therapy: cross-sectional data from the Optimum Patient Care Research Database and the British Thoracic Difficult Asthma Registry

scientific article published on 27 January 2016

Comparison of CT-based Lobar Ventilation with 3He MR Imaging Ventilation Measurements.

scientific article published on 28 August 2015

Comparison of asthma treatment given in addition to inhaled corticosteroids on airway inflammation and responsiveness.

scientific article published on 2 February 2006

Computational modeling of the obstructive lung diseases asthma and COPD.

scientific article

Computed tomography scans in severe asthma: utility and clinical implications

scientific article

Cooperative molecular and cellular networks regulate Toll-like receptor-dependent inflammatory responses.

scientific article

Cough and asthma.

scientific article published on November 2003

Cough due to asthma, cough-variant asthma and non-asthmatic eosinophilic bronchitis.

scientific article published on February 2010

Cough in asthma is due to eosinophilic airway inflammation: a pro/con debate

scientific article

D prostanoid receptor 2 (chemoattractant receptor-homologous molecule expressed on TH2 cells) protein expression in asthmatic patients and its effects on bronchial epithelial cells

scientific article

DP2 antagonism reduces airway smooth muscle mass in asthma by decreasing eosinophilia and myofibroblast recruitment

scientific article published on 01 February 2019

Dedicated severe asthma services improve health-care use and quality of life

scientific article published on 19 March 2015

Defective sirtuin-1 increases IL-4 expression through acetylation of GATA-3 in patients with severe asthma.

scientific article published on 25 November 2015

Destination Airway: Tracking Granulocytes in Asthma

scientific article published on 7 November 2014

Development and Analysis of Patient-Based Complete Conducting Airways Models

scientific article published on 11 December 2015

Development of irreversible airflow obstruction in a patient with eosinophilic bronchitis without asthma

scientific article published in November 1999

Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines

scientific article

Differential Effects of p38, MAPK, PI3K or Rho Kinase Inhibitors on Bacterial Phagocytosis and Efferocytosis by Macrophages in COPD.

scientific article

Dynamic flow characteristics in normal and asthmatic lungs

scientific article

Effect of Anti-IL-13 Treatment on Airway Dimensions in Severe Asthma.

scientific article published in July 2016

Effect of levofloxacin on neutrophilic airway inflammation in stable COPD: a randomized, double-blind, placebo-controlled trial.

scientific article published on 07 February 2014

Effect of the plant derivative Compound A on the production of corticosteroid-resistant chemokines in airway smooth muscle cells.

scientific article published on 21 April 2015

Effect of tralokinumab, an interleukin-13 neutralising monoclonal antibody, on eosinophilic airway inflammation in uncontrolled moderate-to-severe asthma (MESOS): a multicentre, double-blind, randomised, placebo-controlled phase 2 trial

scientific article published on 21 May 2018

Effectiveness of voriconazole in the treatment of Aspergillus fumigatus-associated asthma (EVITA3 study).

scientific article published on 28 November 2013

Effects of older age and age of asthma onset on clinical and inflammatory variables in severe refractory asthma

scientific article published on 9 July 2016

Efficacy and safety of tralokinumab in patients with severe uncontrolled asthma: a randomised, double-blind, placebo-controlled, phase 2b trial.

scientific article published on 28 July 2015

Elevated sputum interleukin-5 and submucosal eosinophilia in obese individuals with severe asthma

scientific article

Emerging Therapies in Severe Eosinophilic Asthma.

scientific article published on 6 March 2017

Eosinophil protein in airway macrophages: a novel biomarker of eosinophilic inflammation in patients with asthma

scientific article published on July 2010

Eosinophilic airway inflammation and exacerbations of COPD: a randomised controlled trial.

scientific article published on 14 February 2007

Eosinophilic airway inflammation in COPD

scientific article published on January 2006

Eosinophilic airway inflammation: role in asthma and chronic obstructive pulmonary disease

scientific article

Eosinophilic bronchitis - what is it and why is it important?

article

Eosinophilic bronchitis is an important cause of chronic cough.

scientific article

Eosinophilic bronchitis: an important cause of prolonged cough.

scientific article

Eosinophilic bronchitis: clinical features, management and pathogenesis.

scientific article published on January 2003

Eosinophils as diagnostic tools in chronic lung disease.

scientific article published on February 2013

Eosinophils best marker of steroid response

scientific article published on 23 September 2010

Eosinophils in asthma and other allergic diseases.

scientific article

Eosinophils, bronchitis and asthma: pathogenesis of cough and airflow obstruction.

scientific article

Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5).

scientific article published on 20 February 2017

Evidence for phenotype-driven treatment in asthmatic patients.

scientific article published on August 2011

Exacerbation Profile and Risk Factors in a Type-2–Low Enriched Severe Asthma Cohort: A Clinical Trial to Assess Asthma Exacerbation Phenotypes

scientific article published in 2022

Exacerbations of severe asthma in patients treated with mepolizumab

scientific article published on 13 December 2018

Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12.

scientific article published on 25 February 2016

Expression and activation of the oxytocin receptor in airway smooth muscle cells: Regulation by TNFalpha and IL-13

scientific article

Expression of CCR8 is increased in asthma

scientific article

Expression of Chemokine Receptors by Lung T Cells from Normal and Asthmatic Subjects

scientific article published on 15 February 2001

Expression of the T helper 17-associated cytokines IL-17A and IL-17F in asthma and COPD.

scientific article

Face mask sampling reveals antimicrobial resistance genes in exhaled aerosols from patients with chronic obstructive pulmonary disease and healthy volunteers

article

Fevipiprant in the treatment of asthma.

scientific article published on 24 January 2018

Fevipiprant, a prostaglandin D2 receptor 2 antagonist, in patients with persistent eosinophilic asthma: a single-centre, randomised, double-blind, parallel-group, placebo-controlled trial.

scientific article

FourFold Asthma Study (FAST): a study protocol for a randomised controlled trial evaluating the clinical cost-effectiveness of temporarily quadrupling the dose of inhaled steroid to prevent asthma exacerbations.

scientific article published on 13 October 2016

Functional KCa3.1 K+ channels are required for human fibrocyte migration

scientific article published on 27 August 2011

Functional KCa3.1 channels regulate steroid insensitivity in bronchial smooth muscle cells

scientific article published on 31 July 2013

Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets

scientific article published on 6 February 2017

Genome-wide association study to identify genetic determinants of severe asthma.

scientific article

Granulocyte-macrophage colony-stimulating factor expression in induced sputum and bronchial mucosa in asthma and COPD

scientific article published on 12 February 2009

HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4.

scientific article published on 23 February 2017

How to diagnose and phenotype asthma.

scientific article published on 07 July 2012

Human airway smooth muscle maintain in situ cell orientation and phenotype when cultured on aligned electrospun scaffolds.

scientific article

Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6

scientific article published on August 2008

Human group 2 innate lymphoid cells do not express the IL-5 receptor.

scientific article published on 10 May 2017

Human lung mast cells modulate the functions of airway smooth muscle cells in asthma.

scientific article

IL-33 drives airway hyper-responsiveness through IL-13-mediated mast cell: airway smooth muscle crosstalk

scientific article published on 16 March 2015

Idiopathic chronic cough and organ-specific autoimmune diseases: a case-control study.

scientific article published in March 2004

Idiopathic chronic cough: association with organ specific autoimmune disease and bronchoalveolar lymphocytosis.

scientific article published on December 2003

IgE sensitization to Aspergillus fumigatus is associated with reduced lung function in asthma.

scientific article

Immunopathogenesis of severe asthma.

scientific article published on January 2011

Impaired Mitochondrial Microbicidal Responses in Chronic Obstructive Pulmonary Disease Macrophages

scientific article published on 30 May 2017

Improving the sampling technique of arterialized capillary samples to obtain more accurate PaO2 measurements.

scientific article published in January 2005

In vivo imaging reveals increased eosinophil uptake in the lungs of obese asthmatic patients

article

Increased glutaredoxin-1 and decreased protein S-glutathionylation in sputum of asthmatics.

scientific article published on February 2013

Increased nicotinamide adenine dinucleotide phosphate oxidase 4 expression mediates intrinsic airway smooth muscle hypercontractility in asthma

scientific article published on 22 November 2011

Increased sputum and bronchial biopsy IL-13 expression in severe asthma

scientific article published on March 2008

Induced Sputum Inflammatory Mediator Concentrations in Eosinophilic Bronchitis and Asthma

scientific article published on 01 September 2000

Induced sputum and bronchial mucosal expression of interleukin-13 is not increased in chronic obstructive pulmonary disease.

scientific article published on September 2008

Induced sputum and other outcome measures in chronic obstructive pulmonary disease: safety and repeatability

scientific article published in December 2001

Integrated care pathways for airway diseases (AIRWAYS-ICPs).

scientific article published on 12 June 2014

Interleukin-4 and -13 expression is co-localized to mast cells within the airway smooth muscle in asthma

scientific article published in December 2003

Investigating the role of pentraxin 3 as a biomarker for bacterial infection in subjects with COPD.

scientific article

Is the eosinophil a leading villain in lung function decline?

scientific article published in October 2015

Isolation of filamentous fungi from sputum in asthma is associated with reduced post-bronchodilator FEV1.

scientific article

Letter from the UK

scientific article published on 19 October 2020

Lung clearance index in adults with non-cystic fibrosis bronchiectasis.

scientific article

Lung damage and airway remodelling in severe asthma.

scientific article published on 22 December 2011

Lung function decline and variable airway inflammatory pattern: longitudinal analysis of severe asthma.

scientific article published on 11 June 2014

Lung microbiome dynamics in COPD exacerbations

scientific article

MACVIA-ARIA Sentinel NetworK for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation.

scientific article published on 04 July 2015

MUC5AC and a Glycosylated Variant of MUC5B Alter Mucin Composition in Children With Acute Asthma.

scientific article published on 14 July 2017

Magic bullets: the new goal for asthma

scientific article published on 01 September 2009

Mast cell infiltration of airway smooth muscle in asthma

scientific article published on 15 February 2007

Mast cell-airway smooth muscle crosstalk: the role of thymic stromal lymphopoietin.

scientific article

Mast cells express IL-13R alpha 1: IL-13 promotes human lung mast cell proliferation and Fc epsilon RI expression

scientific article

Mepolizumab and exacerbations of refractory eosinophilic asthma

scientific article published on March 2009

Mepolizumab does not alter the blood basophil count in severe asthma

scientific article published on 28 June 2019

Mepolizumab for the reduction of exacerbations in severe eosinophilic asthma.

scientific article published on 8 April 2016

Meta-analysis of asthma-related hospitalization in mepolizumab studies of severe eosinophilic asthma

scientific article

Microbiome balance in sputum determined by PCR stratifies COPD exacerbations and shows potential for selective use of antibiotics.

scientific article

Modelling the effect of gravity on inert-gas washout outputs.

scientific article published in May 2018

Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study

scientific article published on 11 December 2018

Multi-scale computational models of the airways to unravel the pathophysiological mechanisms in asthma and chronic obstructive pulmonary disease (AirPROM).

scientific article published on April 2013

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

scientific article published on 22 December 2017

Myeloid-derived suppressor cell-like fibrocytes are increased and associated with preserved lung function in chronic obstructive pulmonary disease.

scientific article published on 6 October 2016

NADPH Oxidase-4 Overexpression Is Associated With Epithelial Ciliary Dysfunction in Neutrophilic Asthma

scientific article published on 02 February 2016

New and emerging drug treatments for severe asthma.

scientific article

No evidence for altered intracellular calcium-handling in airway smooth muscle cells from human subjects with asthma

scientific article

Non-eosinophilic cor ticosteroid unresponsive asthma

scientific article published in June 1999

Novel imaging approaches in adult asthma and their clinical potential.

scientific article published on 10 August 2015

OX40/OX40 ligand interactions in T-cell regulation and asthma

scientific article published on February 2012

Obesity-associated severe asthma represents a distinct clinical phenotype: analysis of the British Thoracic Society Difficult Asthma Registry Patient cohort according to BMI.

scientific article published in February 2013

Opsonic Phagocytosis in Chronic Obstructive Pulmonary Disease is Enhanced by Nrf2 Agonists.

scientific article

Origins of increased airway smooth muscle mass in asthma.

scientific article

Outcomes after cessation of mepolizumab therapy in severe eosinophilic asthma: a 12-month follow-up analysis

scientific article published on 10 January 2014

Oxidation of the alarmin IL-33 regulates ST2-dependent inflammation

scientific article

Pathogenesis of asthma: implications for precision medicine.

scientific article

Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma.

scientific article

Pathophysiological regulation of lung function by the free fatty acid receptor FFA4

scientific article published on 01 August 2020

Pre-eclampsia is associated with airway hyperresponsiveness.

scientific article

Prednisolone response in patients with COPD.

scientific article published on February 2004

Primary human airway epithelial cell-dependent inhibition of human lung mast cell degranulation.

scientific article

Procalcitonin and C-reactive protein in hospitalized adult patients with community-acquired pneumonia or exacerbation of asthma or COPD. ⬇️

scientific article

Protein phosphatase 5 mediates corticosteroid insensitivity in airway smooth muscle in patients with severe asthma.

scientific article published on 9 August 2016

Quadrupling Inhaled Glucocorticoid Dose to Abort Asthma Exacerbations.

scientific article published on 3 March 2018

Qualitative analysis of high-resolution CT scans in severe asthma

scientific article

Quantitative analysis of high-resolution computed tomography scans in severe asthma subphenotypes.

scientific article

Quantitative computed tomography-derived clusters: redefining airway remodeling in asthmatic patients.

scientific article

Regional Ventilation Changes in the Lung: Treatment Response Mapping by Using Hyperpolarized Gas MR Imaging as a Quantitative Biomarker

scientific article published on 4 May 2017

Regulator of G-protein signaling-5 inhibits bronchial smooth muscle contraction in severe asthma.

scientific article

Relationship between blood and bronchial submucosal eosinophilia and reticular basement membrane thickening in chronic obstructive pulmonary disease

scientific article published on 27 January 2015

Relationship between lung function and quantitative computed tomographic parameters of airway remodeling, air trapping, and emphysema in patients with asthma and chronic obstructive pulmonary disease: A single-center study

scientific article published on 19 March 2016

Reply: To PMID 24238646.

scientific article published in May 2014

Research in progress: Medical Research Council United Kingdom Refractory Asthma Stratification Programme (RASP-UK)

scientific article (publication date: February 2016)

Responsiveness to oral prednisolone in severe asthma is related to the degree of eosinophilic airway inflammation.

scientific article published on 10 May 2017

Rhinitis associated with asthma is distinct from rhinitis alone: The <scp>ARIA‐MeDALL</scp> hypothesis

scientific article published in 2023

Routine processing procedures for isolating filamentous fungi from respiratory sputum samples may underestimate fungal prevalence.

scientific article

Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)

scientific article

Section 3. A discussion of flexible dosing and patient-centered therapy: highlights of the asthma summit 2009: beyond the guidelines

scientific article published on 15 February 2010

Severe asthma: Differential chemokine response of airway epithelial cells

scientific article published on 12 April 2017

Severe asthma: a consequence of over exuberant repair?

scientific article published on 15 September 2009

Sputum IL-5 concentration is associated with a sputum eosinophilia and attenuated by corticosteroid therapy in COPD

scientific article published on 27 May 2009

Sputum Inflammatory Mediators Are Increased in Aspergillus fumigatus Culture-Positive Asthmatics

scientific article published on March 2017

Sputum and bronchial submucosal IL-13 expression in asthma and eosinophilic bronchitis.

scientific article published in November 2004

Sputum eosinophilia and short-term response to prednisolone in chronic obstructive pulmonary disease: a randomised controlled trial

scientific article published in October 2000

Sputum eosinophilia and the short term response to inhaled mometasone in chronic obstructive pulmonary disease.

scientific article published on March 2005

Sputum eosinophilia in idiopathic pulmonary fibrosis.

scientific article

Sputum induction in asthma: a research technique or a clinical tool?

scientific article published in March 2006

Sputum microbiome temporal variability and dysbiosis in chronic obstructive pulmonary disease exacerbations: an analysis of the COPDMAP study.

scientific article

Sputum strains exhibit diversity within and between COPD subjects

scientific article published on 08 November 2018

Statistical cluster analysis of the British Thoracic Society Severe refractory Asthma Registry: clinical outcomes and phenotype stability

scientific article

Synthetic response of stimulated respiratory epithelium: modulation by prednisolone and iKK2 inhibition.

scientific article

Systemic and pulmonary inflammation is independent of skeletal muscle changes in patients with chronic obstructive pulmonary disease.

scientific article

Systems medicine and integrated care to combat chronic noncommunicable diseases

scientific article

TH2 cytokine expression in bronchoalveolar lavage fluid T lymphocytes and bronchial submucosa is a feature of asthma and eosinophilic bronchitis.

scientific article published in December 2002

TNF-Alpha Antagonism in Severe Asthma? ⬇️

scientific article published on November 1, 2010

Targeting TNF-alpha: a novel therapeutic approach for asthma

scientific article

Temporal assessment of airway remodeling in severe asthma using quantitative computed tomography.

scientific article published in January 2015

Temporarily quadrupling the dose of inhaled steroid to prevent asthma exacerbations: FAST

scientific article published on 01 December 2018

The CXCL10/CXCR3 Axis Mediates Human Lung Mast Cell Migration to Asthmatic Airway Smooth Muscle

scientific article published on 15 May 2005

The EvA study: aims and strategy.

scientific article

The RAGE against the storm

scientific article published on 01 March 2012

The airway smooth muscle CCR3/CCL11 axis is inhibited by mast cells.

scientific article published on September 2008

The cost of treating severe refractory asthma in the UK: an economic analysis from the British Thoracic Society Difficult Asthma Registry.

scientific article published on 10 June 2014

The effects of nociceptin peptide (N/OFQ)-receptor (NOP) system activation in the airways.

scientific article

The impact of the prostaglandin D2 receptor 2 and its downstream effects on the pathophysiology of asthma

scientific article published on 29 July 2019

The influence of age on induced sputum differential cell counts in normal subjects

scientific article published in December 2004

The reclassification of asthma based on subphenotypes.

scientific article published on February 2007

The role of oral methotrexate as a steroid sparing agent in refractory eosinophilic asthma

scientific article published on January 2017

The sputum microbiome is distinct between COPD and health, independent of smoking history

scientific article published on 14 July 2020

The use of exhaled nitric oxide concentration to identify eosinophilic airway inflammation: an observational study in adults with asthma.

scientific article published in September 2005

The use of exhaled nitric oxide to guide asthma management: a randomized controlled trial

scientific article published on 11 May 2007

The utility of the mannitol challenge in the assessment of chronic cough: a pilot study

scientific article published on 18 November 2008

Toll-like receptor 9 dependent interferon-α release is impaired in severe asthma but is not associated with exacerbation frequency.

scientific article published on 22 January 2015

Tralokinumab for severe, uncontrolled asthma (STRATOS 1 and STRATOS 2): two randomised, double-blind, placebo-controlled, phase 3 clinical trials

scientific article published on 20 May 2018

Unmet needs for the assessment of small airways dysfunction in asthma: introduction to the ATLANTIS study

scientific article published in June 2015

Urgent need for pragmatic trial platforms in severe asthma

scientific article published on 01 August 2018

Vascular remodeling is a feature of asthma and nonasthmatic eosinophilic bronchitis

scientific article published in October 2007

Wheeze and eosinophilic airway inflammation equals asthma?

scientific article published on 01 January 2001

[Ca2+]i oscillations in ASM: relationship with persistent airflow obstruction in asthma

scientific article

uPAR regulates bronchial epithelial repair in vitro and is elevated in asthmatic epithelium.

scientific article published on 3 December 2011

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