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List of works by Peter D Clegg

A comparison of 3-T magnetic resonance imaging and computed tomography arthrography to identify structural cartilage defects of the fetlock joint in the horse.

scientific article published on 26 October 2013

A comparison of the stem cell characteristics of murine tenocytes and tendon-derived stem cells.

scientific article published on 12 April 2018

A cross-sectional study of geriatric horses in the United Kingdom. Part 1: Demographics and management practices.

scientific article published on 23 August 2010

A cross-sectional study of geriatric horses in the United Kingdom. Part 2: Health care and disease.

scientific article published on 23 August 2010

A proteomic analysis of chondrogenic, osteogenic and tenogenic constructs from ageing mesenchymal stem cells

scientific article published on 14 September 2016

A review of tendon injury: why is the equine superficial digital flexor tendon most at risk?

scientific article published on March 2010

A study of the anatomy and injection techniques of the ovine stifle by positive contrast arthrography, computed tomography arthrography and gross anatomical dissection

scientific article published on 20 January 2012

A survey of health care and disease in geriatric horses aged 30 years or older

scientific article published on 06 May 2011

A systems biology approach to defining regulatory mechanisms for cartilage and tendon cell phenotypes.

scientific article published on 27 September 2016

A test of the universal applicability of a commonly used principle of hoof balance.

scientific article published on 13 October 2015

A topographic anatomical study of the equine epiploic foramen and comparison with laparoscopic visualisation.

scientific article published on 25 June 2014

Absolute quantification of selected proteins in the human osteoarthritic secretome.

scientific article

Accuracy of computed tomographic arthrography for assessment of articular cartilage defects in the ovine stifle.

scientific article published on 20 April 2017

Advances in the understanding of tendinopathies: A report on the Second Havemeyer Workshop on equine tendon disease

article

Age-related changes in mesenchymal stem cells identified using a multi-omics approach

scientific article published on 8 February 2016

Age-related morphometric changes of the tidemark in the ovine stifle

scientific article published on 20 May 2019

Ageing does not result in a decline in cell synthetic activity in an injury prone tendon

scientific article published on 9 June 2015

An anatomic study of the calcaneal bursae in the horse

scientific article published on 01 January 2007

An exploration of the ability of tepoxalin to ameliorate the degradation of articular cartilage in a canine in vitro model

scientific article published on 22 July 2009

Analysis of horse race videos to identify intra-race risk factors for fatal distal limb fracture

article

Analysis of post transcriptional regulation of SOX9 mRNA during in vitro chondrogenesis

scientific article published on 18 April 2011

Analysis of risk factors associated with antibiotic-resistant Escherichia coli

scientific article published on 9 January 2012

Anatomical heterogeneity of tendon: Fascicular and interfascicular tendon compartments have distinct proteomic composition

scientific article published on 4 February 2016

Antimicrobial prescribing practice in UK equine veterinary practice

scientific article published on 19 September 2012

Antimicrobial resistance changes in enteric Escherichia coli of horses during hospitalisation: Resistance profiling of isolates ⬇️

scientific article published on September 8, 2012

Antimicrobial resistance in bacteria from horses: Epidemiology of antimicrobial resistance.

scientific article published on 18 June 2015

Antimicrobial resistance in dogs and horses

scientific article published in January 2008

Antimicrobial resistance in equine faecal Escherichia coli isolates from North West England

scientific article

Antimicrobial resistance in the horse - EVJ's online collection.

scientific article

Aquaporin water channels AQP1 and AQP3, are expressed in equine articular chondrocytes.

scientific article

Aspartic acid racemization and collagen degradation markers reveal an accumulation of damage in tendon collagen that is enhanced with aging

scientific article

Assessment of the use of RNA quality metrics for the screening of articular cartilage specimens from clinically normal dogs and dogs with osteoarthritis

scientific article published on 01 August 2006

Biomarkers for equine joint injury and osteoarthritis

scientific article published on 16 September 2017

Biomarkers of cartilage turnover. Part 1: Markers of collagen degradation and synthesis

scientific article published on 21 May 2010

Biomarkers of cartilage turnover. Part 2: Non-collagenous markers.

scientific article published on 21 May 2010

Book Reviews

CT-guided injection technique into intervertebral discs in the ovine lumbar spine

scientific article

Carriage of Staphylococcus species in the veterinary visiting dog population in mainland UK: molecular characterisation of resistance and virulence.

scientific article published on 2 February 2014

Carriage of antimicrobial resistant Escherichia coli in dogs: Prevalence, associated risk factors and molecular characteristics

scientific article published on 23 November 2016

Cartilage damage involving extrusion of mineralisable matrix from the articular calcified cartilage and subchondral bone

scientific article published on 28 May 2011

Catastrophic fracture of the lateral condyle of the third metacarpus/metatarsus in UK racehorses – fracture descriptions and pre-existing pathology

article

Cell phenotypic variation in normal and damaged tendons.

scientific article published on August 2007

Characterization of neopeptides in equine articular cartilage degradation

scientific article published on 29 June 2015

Chondrocyte apoptosis, inflammatory mediators and equine osteoarthritis

scientific article published on 01 July 2003

Chondrocytes harvested from osteochondritis dissecans cartilage are able to undergo limited in vitro chondrogenesis despite having perturbations of cell phenotype in vivo

scientific article published on 01 August 2008

Clinical insights: Recent developments in equine articular disease (2016-2018)

scientific article published on 01 November 2018

Clinical research: developing an appropriate career structure

scientific article published in November 2015

Collection and propagation methods for mesenchymal stromal cells.

scientific article published on August 2011

Communication between the distal interphalangeal joint and the navicular bursa in the horse at Computed Tomography Arthrography

scientific article published on 04 January 2019

Comparative rheumatology: what can be learnt from naturally occurring musculoskeletal disorders in domestic animals?

scientific article published on 21 February 2010

Comparison between chaotropic and detergent-based sample preparation workflow in tendon for mass spectrometry analysis.

scientific article

Comparison of owner-reported health problems with veterinary assessment of geriatric horses in the United Kingdom

scientific article published on 23 June 2011

Complete and partial hoof wall resection for keratoma removal: post operative complications and final outcome in 26 horses (1994-2004).

scientific article

Comprehensive protein profiling of synovial fluid in osteoarthritis following protein equalization

scientific article published on 26 March 2015

Computed Tomography and Magnetic Resonance Anatomy of the Normal Orbit and Eye of the Horse.

scientific article published on 8 October 2014

Computed tomography to identify preoperative guidelines for internal fixation of the distal sesamoid bone in horses: an in vitro study

scientific article published on 15 November 2010

Cross platform analysis of transcriptomic data identifies ageing has distinct and opposite effects on tendon in males and females.

scientific article published on 31 October 2017

Cross-sectional study of antimicrobial-resistant bacteria in horses. Part 1: Prevalence of antimicrobial-resistant Escherichia coli and methicillin-resistant Staphylococcus aureus.

scientific article published on 18 August 2011

Cross-sectional study of antimicrobial-resistant bacteria in horses. Part 2: Risk factors for faecal carriage of antimicrobial-resistant Escherichia coli in horses

scientific article published on 18 August 2011

Cross-sectional survey of antimicrobial prescribing patterns in UK small animal veterinary practice.

scientific article published on 4 January 2012

Cross-species gene modules emerge from a systems biology approach to osteoarthritis.

scientific article

Decoding the Regulatory Landscape of Ageing in Musculoskeletal Engineered Tissues Using Genome-Wide DNA Methylation and RNASeq.

scientific article

Destructive lesions of the proximal sesamoid bones as a complication of dorsal metatarsal artery catheterization in three horses.

scientific article

Developing a toolkit for the assessment and monitoring of musculoskeletal ageing

scientific article published on 01 September 2018

Differential regulation of the GLUT1 and GLUT3 glucose transporters by growth factors and pro-inflammatory cytokines in equine articular chondrocytes.

scientific article published in March 2005

Differential tissue specific, temporal and spatial expression patterns of the Aggrecan gene is modulated by independent enhancer elements

scientific article published on 17 January 2018

Disease prevalence in geriatric horses in the United Kingdom: Veterinary clinical assessment of 200 cases ⬇️

scientific article published on June 13, 2011

Distribution of proteins within different compartments of tendon varies according to tendon type.

scientific article published on 25 April 2016

Distribution of purinergic P2X receptors in the equine digit, cervical spinal cord and dorsal root ganglia.

scientific article published on 6 February 2013

Donor age affects proteome composition of tenocyte-derived engineered tendon

scientific article published on 16 January 2018

Effect of Fatigue Loading on Tendon Fascicle Extension Mechanisms

scientific article published on 26 June 2013

Effect of corticosteroids on articular cartilage: have animal studies said everything?

scientific article published on 27 July 2015

Effect of fatigue loading on structure and functional behaviour of fascicles from energy-storing tendons.

scientific article published on 18 April 2014

Effects of hypoxia on glucose transport in primary equine chondrocytes in vitro and evidence of reduced GLUT1 gene expression in pathologic cartilage in vivo.

scientific article published in April 2009

Elastin content is high in the canine cruciate ligament and is associated with degeneration

scientific article published on 11 November 2013

Endoscopic resection of dorsal spinous processes and interspinous ligament in ten horses

scientific article published on 01 February 2007

Epigenetic mechanisms in Tendon Ageing

scientific article published on 22 August 2020

Equine synovial fluid small non-coding RNA signatures in early osteoarthritis

scientific article published on 09 January 2021

Equine welfare: Risk of horses falling in the Grand National

article

Evaluation of cartilage, synovium and adipose tissue as cellular sources for osteochondral repair ⬇️

scientific article published on July 22, 2013

Evidence-based medicine and stem cell therapy: how do we know such technologies are safe and efficacious?

scientific article published on 12 June 2011

Ex-Vivo Equine Cartilage Explant Osteoarthritis Model - A Metabolomics and Proteomics Study

scientific article published on 23 July 2020

Expression of matrix metalloproteinases, their inhibitors, and lysyl oxidase in myocardial samples from dogs with end-stage systemic and cardiac diseases.

scientific article published in February 2013

Expression of purinergic P2X receptor subtypes 1, 2, 3 and 7 in equine laminitis

scientific article published on 20 August 2013

Factors associated with mortality of geriatric horses in the United Kingdom.

scientific article published on 5 July 2011

Fascicles and the interfascicular matrix show adaptation for fatigue resistance in energy storing tendons

scientific article published on 07 June 2016

Fascicles and the interfascicular matrix show decreased fatigue life with ageing in energy storing tendons.

scientific article published on 16 March 2017

Fascicles from energy-storing tendons show an age-specific response to cyclic fatigue loading

scientific article

Gene expression markers of tendon fibroblasts in normal and diseased tissue compared to monolayer and three dimensional culture systems.

scientific article

Haemoperitoneum in horses: a retrospective review of 54 cases.

scientific article published on October 2010

Helical sub-structures in energy-storing tendons provide a possible mechanism for efficient energy storage and return.

scientific article

Heterogeneity of proteome dynamics between connective tissue phases of adult tendon

scientific article published on 12 May 2020

High-intensity exercise induces structural, compositional and metabolic changes in cuboidal bones — findings from an equine athlete model

article

Horse-, training- and race-level risk factors for palmar/plantar osteochondral disease in the racing Thoroughbred.

scientific article published on 20 February 2013

How can veterinarians base their medical decisions on the best available scientific evidence?

scientific article published on 14 January 2012

Hyperosmolarity regulates SOX9 mRNA posttranscriptionally in human articular chondrocytes

scientific article published on 5 August 2009

Identification and Characterization of Canine Ligament Progenitor Cells and Their Extracellular Matrix Niche

scientific article published on 07 February 2019

Identification of Equid herpesvirus 2 in tissue-engineered equine tendon.

scientific article published on 17 October 2017

Identification of risk factors for traumatic injury in the general horse population of north-west England, Midlands and north Wales.

scientific article published on 23 June 2011

Increased blood mRNA expression of inflammatory and anti-fibrotic markers in dogs with congestive heart failure ⬇️

scientific article published on November 17, 2011

Influence of Ageing on Tendon Homeostasis

scientific article

Innervation and nerve injections of the lumbar spine of the horse: a cadaveric study.

scientific article published in January 2007

Interaction with macrophages attenuates Equine Fibroblast-Like Synoviocyte ADAMTS5 (aggrecanase-2) gene expression following inflammatory stimulation.

scientific article published on 9 March 2018

Investigating the efficacy of articular medications in the horse: the science behind clinical practices

scientific article published on 01 September 2010

Is evidence-based medicine so evident in veterinary research and practice? History, obstacles and perspectives.

scientific article published on 26 May 2011

Isothiocyanates are detected in human synovial fluid following broccoli consumption and can affect the tissues of the knee joint

scientific article

John Bastin 1929–2018

Leptin expression in dogs with cardiac disease and congestive heart failure.

scientific article published on 30 August 2011

Letter to the Editor: Equine Veterinary Journal's antimicrobial stewardship policy.

scientific article published in July 2016

Ligament-Derived Stem Cells: Identification, Characterisation, and Therapeutic Application

scientific article published on 12 March 2017

Local anaesthetics or their combination with morphine and/or magnesium sulphate are toxic for equine chondrocytes and synoviocytes in vitro.

scientific article

Longitudinal study of antimicrobial-resistant commensal Escherichia coli in the faeces of horses in an equine hospital.

scientific article published on 4 March 2011

MMP-mediated collagen breakdown induced by activated protein C in equine cartilage is reduced by corticosteroids.

scientific article published in March 2010

MT3-MMP (MMP-16) is downregulated by in vitro cytokine stimulation of cartilage, but unaltered in naturally occurring equine osteoarthritis and osteochondrosis

scientific article published on 01 January 2008

Magnetic resonance compositional imaging of articular cartilage: What can we expect in veterinary medicine?

scientific article published on 04 May 2015

Magnetic resonance imaging (MRI) anatomy of the ovine lumbar spine

scientific article published on 14 May 2013

Magnetic resonance imaging (MRI) anatomy of the ovine stifle

scientific article published on 24 May 2013

Matrix assisted laser desorption ionization mass spectrometry imaging identifies markers of ageing and osteoarthritic cartilage.

scientific article

Matrix metabolism rate differs in functionally distinct tendons

scientific article

Mesenchymal stem cell therapy in equine musculoskeletal disease: scientific fact or clinical fiction?

scientific article

Methicillin-resistant staphylococci in companion animals

scientific article

MicroRNA Profiling in Cartilage Ageing.

scientific article published on 14 August 2017

Microwave ablation: results with a 2.45-GHz applicator in ex vivo bovine and in vivo porcine liver

scientific article published on 16 February 2006

Mouse microRNA signatures in joint ageing and post-traumatic osteoarthritis

scientific article published on 01 December 2021

Muc5b and Muc5ac are the major oligomeric mucins in equine airway mucus

scientific article published on 9 February 2007

Muc5b is the major polymeric mucin in mucus from thoroughbred horses with and without airway mucus accumulation

scientific article

Musculoskeletal disease and injury, now and in the future. Part 1: fractures and fatalities.

scientific article published on 21 September 2011

Musculoskeletal disease and injury, now and in the future. Part 2: Tendon and ligament injuries.

scientific article published on May 2012

Myocardial cytokine expression in dogs with systemic and naturally occurring cardiac diseases.

scientific article published in March 2013

Nutraceutical therapies for degenerative joint diseases: a critical review.

scientific article

Optimization of Synovial Fluid Collection and Processing for NMR Metabolomics and LC-MS/MS Proteomics

scientific article published on 07 April 2020

Oxygen and pH-sensitivity of human osteoarthritic chondrocytes in 3-D alginate bead culture system ⬇️

scientific article published on July 11, 2013

Pathological and clinical features associated with palmar/plantar osteochondral disease of the metacarpo/metatarsophalangeal joint in Thoroughbred racehorses.

scientific article published on 19 February 2013

Post anaesthetic colic in horses: a preventable complication?

scientific article published in September 2006

Post mortem evaluation of palmar osteochondral disease (traumatic osteochondrosis) of the metacarpo/metatarsophalangeal joint in Thoroughbred racehorses

scientific article published on 01 April 2009

Post-transcriptional gene regulation following exposure of osteoarthritic human articular chondrocytes to hyperosmotic conditions.

scientific article published on 19 May 2011

Post-transcriptional gene regulation in chondrocytes

scientific article published on 01 December 2010

Postnatal mechanical loading drives adaptation of tissues primarily through modulation of the non-collagenous matrix

scientific article published on 16 October 2020

Preparation and Culture of Myogenic Precursor Cells/Primary Myoblasts from Skeletal Muscle of Adult and Aged Humans

scientific article

Prevalence of Age-Related Changes in Ovine Lumbar Intervertebral Discs during Computed Tomography and Magnetic Resonance Imaging

scientific article published on January 2016

Prevalence of naturally occurring cartilage defects in the ovine knee ⬇️

scientific article published on May 22, 2013

Proposed Definitions and Criteria for Reporting Time Frame, Outcome, and Complications For Clinical Orthopedic Studies in Veterinary Medicine

article

Proteomic analysis of polymeric salivary mucins: no evidence for MUC19 in human saliva.

scientific article published on August 2008

Proteomic analysis reveals age-related changes in tendon matrix composition, with age- and injury-specific matrix fragmentation

scientific article

RNA binding proteins regulate anabolic and catabolic gene expression in chondrocytes.

scientific article published on 4 February 2016

Regulation of SOX9 in normal and osteoarthritic equine articular chondrocytes by hyperosmotic loading.

scientific article published on 26 August 2010

Repair or destruction: Optimising therapies for joint diseases ⬇️

scientific article published on 01 July 2012

Reported morbidities following 861 anaesthetics given at four equine hospitals.

scientific article published in March 2007

Restricted differentiation potential of progenitor cell populations obtained from the equine superficial digital flexor tendon (SDFT).

scientific article published on June 2015

Resveratrol and N-acetylcysteine influence redox balance in equine articular chondrocytes under acidic and very low oxygen conditions.

scientific article published on 18 May 2015

Retrospective study of the risk factors and prevalence of colic in horses after orthopaedic surgery.

scientific article published in September 2004

SOX9 transduction of a human chondrocytic cell line identifies novel genes regulated in primary human chondrocytes and in osteoarthritis

scientific article

Science in brief: Report on the Havemeyer Foundation workshop on equine musculoskeletal biomarkers--current knowledge and future needs.

scientific article published in November 2014

Science in brief: recent advances into understanding tendon function and injury risk.

scientific article

Serum snoRNAs as biomarkers for joint ageing and post traumatic osteoarthritis

scientific article published on 02 March 2017

Short-term temporal alterations in magnetic resonance signal occur in primary lesions identified in the deep digital flexor tendon of the equine digit.

scientific article

Skeletal scintigraphy in the horse: current indications and validity as a diagnostic test.

scientific article

Specialization of tendon mechanical properties results from interfascicular differences

scientific article

Stem Cells for Cartilage Repair: Preclinical Studies and Insights in Translational Animal Models and Outcome Measures.

scientific article published on 5 February 2018

Stem cell-based therapies for bone repair.

scientific article published in August 2011

Stem cells in veterinary medicine--attempts at regenerating equine tendon after injury

scientific article (publication date: September 2007)

Structure-function Specialisation of the Interfascicular Matrix in the Human Achilles Tendon

scientific article published on 22 February 2021

Structure-function specialisation of the interfascicular matrix in the human achilles tendon

scientific article published in September 2021

Synovial Fluid Metabolites Differentiate between Septic and Nonseptic Joint Pathologies

scientific article published on 20 July 2018

Systematic Review of Efficacy of Nutraceuticals to Alleviate Clinical Signs of Osteoarthritis ⬇️

scientific article published on 09 March 2012

Systems approaches in osteoarthritis: Identifying routes to novel diagnostic and therapeutic strategies

scientific article published on 20 March 2017

TNF-alpha SNP haplotype frequencies in equidae.

scientific article

Tendon Physiology and Mechanical Behavior

scientific article published in 2015

Tendon extracellular matrix damage, degradation and inflammation in response to in vitro overload exercise.

scientific article published on June 2015

Tendon overload results in alterations in cell shape and increased markers of inflammation and matrix degradation

scientific article published on 30 December 2014

The Interfascicular Matrix of Energy Storing Tendons Houses Heterogenous Cell Populations Disproportionately Affected by Aging

scientific article published in 2023

The effect of exercise on the protein profile of rat knee joint intra‐ and extra‐articular ligaments

scientific article published on 13 August 2021

The histological features of microwave coagulation therapy: an assessment of a new applicator design

scientific article published on 01 February 2003

The in vitro effects of antibiotics on cell viability and gene expression of equine bone marrow-derived mesenchymal stromal cells

scientific article published on 01 September 2011

The influence of donor and hypoxic conditions on the assembly of cartilage matrix by osteoarthritic human articular chondrocytes on Hyalograft matrices

scientific article published on 05 November 2008

The interfascicular matrix enables fascicle sliding and recovery in tendon, and behaves more elastically in energy storing tendons

scientific article

The organisation of elastin and fibrillins 1 and 2 in the cruciate ligament complex

scientific article

The role of endogenous and exogenous enzymes in chronic wounds: a focus on the implications of aberrant levels of both host and bacterial proteases in wound healing

scientific article published on March 2012

The role of polyphosphates in the sequestration of matrix metalloproteinases

scientific article published on 17 April 2013

The role of the non‐collagenous matrix in tendon function ⬇️

scientific article published on May 30, 2013

The synovial fluid proteome differentiates between septic and nonseptic articular pathologies

scientific article published on 25 April 2019

Therapeutic Potential of Dental Pulp Stem Cells and Leukocyte- and Platelet-Rich Fibrin for Osteoarthritis

scientific article published on 15 April 2020

Therapy for osteoarthritis in the horse - how do we know that it works?

scientific article published on 01 January 2006

Transcriptome analysis of ageing in uninjured human Achilles tendon.

scientific article

Transcriptome-wide analysis of messenger RNA decay in normal and osteoarthritic human articular chondrocytes

scientific article

Transcriptomic profiling of cartilage ageing.

scientific article published on 19 March 2014

Transcriptomic signatures in cartilage ageing

scientific article

Treatment of recurrent luxation of the shoulder in an alpaca.

scientific article published in March 2007

Treatment of septic common digital extensor tenosynovitis by complete resection in seven horses.

scientific article published on March 2004

Ultrasound anatomy of the normal stifle in the sheep

scientific article published on 22 November 2018

Understanding veterinary practitioners' decision-making process: implications for veterinary medical education

scientific article published on 01 January 2012

Use of computed tomography in standing position to identify guidelines for screw insertion in the distal phalanx of horses: an ex vivo study.

scientific article

Use of computed tomography to diagnose new bone formation associated with desmitis of the proximal aspect of the suspensory ligament in third metacarpal or third metatarsal bones of three horses

scientific article published on 01 February 2009

Using systematic reviews to critically appraise the scientific information for the bovine veterinarian

scientific article published on March 2012

Validation of a client-based clinical metrology instrument for the evaluation of canine elbow osteoarthritis.

scientific article published on June 2009

Variation in the Quantity of Elastic Fibres with Degeneration in Canine Cranial Cruciate Ligaments from Labrador Retrievers.

scientific article published in November 2017

Variations during ageing in the three-dimensional anatomical arrangement of fascicles within the equine superficial digital flexor tendon

scientific article published on 13 February 2018

Variations in cell morphology in the canine cruciate ligament complex

scientific article published on 31 March 2012

miR-24 and its target gene Prdx6 regulate viability and senescence of myogenic progenitors during aging

scientific article published on 24 September 2021

Chronic equine wounds: what is the role of infection and biofilms?.

scientific article published on June 2010

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