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List of works by Isabel Gonzalez-Alvarez

A new mathematical approach for the estimation of the AUC and its variability under different experimental designs in preclinical studies.

scientific article published on 25 January 2011

A topological substructural approach for the prediction of P-glycoprotein substrates

scientific article published on 01 March 2006

Assessment of the Regulatory Methods for the Comparison of Highly Variable Dissolution Profiles.

scientific article published on 29 August 2016

Availability of Authorizations from EMA and FDA for Age-Appropriate Medicines Contained in the WHO Essential Medicines List for Children 2019

scientific article published on 01 April 2020

Biomimetic Artificial Membrane Permeability Assay over Franz Cell Apparatus Using BCS Model Drugs

scientific article published on 19 October 2020

Biopharmaceutical optimization in neglected diseases for paediatric patients by applying the provisional paediatric biopharmaceutical classification system

scientific article published on 17 July 2018

Classification of WHO Essential Oral Medicines for Children Applying a Provisional Pediatric Biopharmaceutics Classification System

scientific article published on 31 October 2019

Evaluation of the intestinal permeability of rosemary (Rosmarinus officinalis L.) extract polyphenols and terpenoids in Caco-2 cell monolayers.

scientific article

Exploring different strategies for imbalanced ADME data problem: case study on Caco-2 permeability modeling.

scientific article

In Silico Prediction of Caco-2 Cell Permeability by a Classification QSAR Approach

scientific article

In Vitro Dissolution as a Tool for Formulation Selection: Telmisartan Two-Step IVIVC

scientific article published on 17 May 2018

In Vivo Predictive Dissolution (IPD) for Carbamazepine Formulations: Additional Evidence Regarding a Biopredictive Dissolution Medium

scientific article published on 17 June 2020

In vitro-in situ permeability and dissolution of fexofenadine with kinetic modeling in the presence of sodium dodecyl sulfate

scientific article published on 11 August 2011

Intestinal Permeability Study of Clinically Relevant Formulations of Silibinin in Caco-2 Cell Monolayers ⬇️

scientific article published on 31 March 2019

Investigation to Explain Bioequivalence Failure in Pravastatin Immediate-Release Products

scientific article published on 09 December 2019

Ion-pair strategy for enabling amifostine oral absorption: rat in situ and in vivo experiments.

scientific article published on 2 May 2013

Ionic Hydrogel Based on Chitosan Cross-Linked with 6-Phosphogluconic Trisodium Salt as a Drug Delivery System

scientific article published on 14 March 2018

Kinetic modelling of the intestinal transport of sarafloxacin. Studies in situ in rat and in vitro in Caco-2 cells.

scientific article published on April 2005

New Insights of Oral Colonic Drug Delivery Systems for Inflammatory Bowel Disease Therapy

scientific article published on 05 September 2020

PAMPA--a drug absorption in vitro model 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones.

scientific article published in March 2004

Permeability Study of Polyphenols Derived from a Phenolic-Enriched Hibiscus sabdariffa Extract by UHPLC-ESI-UHR-Qq-TOF-MS.

scientific article published on 7 August 2015

Population pharmacokinetic model of lithium and drug compliance assessment

scientific article published on 16 November 2016

Progress in the development of early diagnosis and a drug with unique pharmacology to improve cancer therapy

scientific article published on October 2008

Provisional Classification and in Silico Study of Biopharmaceutical System Based on Caco-2 Cell Permeability and Dose Number

scientific article published on 15 May 2013

Segmental-Dependent Solubility and Permeability as Key Factors Guiding Controlled Release Drug Product Development

scientific article published on 24 March 2020

Semi-physiologic model validation and bioequivalence trials simulation to select the best analyte for acetylsalicylic acid.

scientific article

The Use of Rule-Based and QSPR Approaches in ADME Profiling: A Case Study on Caco-2 Permeability.

scientific article published on 15 May 2013

Tubulin acetylation promoting potency and absorption efficacy of deacetylase inhibitors.

scientific article

Validation of a semi-physiological model for caffeine in healthy subjects and cirrhotic patients.

scientific article published on 2 April 2015

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