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List of works by Hyuk-Jin Cha

A Theoretical Model for the Cell Cycle and Drug Induced Cell Cycle Arrest of FUCCI Systems with Cell-to-Cell Variation during Mitosis

scientific article published on 22 February 2019

A fluorescent chemical probe CDy9 selectively stains and enables the isolation of live naïve mouse embryonic stem cells

article by Seung-Ju Cho et al published October 2018 in Biomaterials

Accelerated wound healing by S-methylmethionine sulfonium: evidence of dermal fibroblast activation via the ERK1/2 pathway.

scientific article published on 21 January 2010

BCL2 induced by LAMTOR3/MAPK is a druggable target of chemoradioresistance in mesenchymal lung cancer.

scientific article

Chronic TGFβ stimulation promotes the metastatic potential of lung cancer cells by Snail protein stabilization through integrin β3-Akt-GSK3β signaling

scientific article published on 23 March 2016

Connectivity map-based drug repositioning of bortezomib to reverse the metastatic effect of GALNT14 in lung cancer

scientific article published on 09 May 2020

Control of stress signaling in stem cells: crossroads of stem cells and cancer

scientific article

Corrigendum: Rh D blood group conversion using transcription activator-like effector nucleases

scientific article published on 22 October 2015

Current status of biology, bioengineering, and therapeutic potential of stem cells

scientific article published on 01 February 2012

Designing Tyrosinase siRNAs by Multiple Prediction Algorithms and Evaluation of Their Anti-Melanogenic Effects

scientific article published on 8 December 2017

Effect of ionizing radiation induced damage of endothelial progenitor cells in vascular regeneration.

scientific article

Ell3 stimulates 5-FU resistance in a breast cancer cell line

scientific article

Enhancement of wound healing efficiency mediated by artificial dermis functionalized with EGF or NRG1.

scientific article published in February 2018

Extract of Aneilema keisak inhibits transforming growth factor‐β‐dependent signalling by inducing Smad2 downregulation in keloid fibroblasts ⬇️

scientific article published on January 1, 2013

FBXL14 abolishes breast cancer progression by targeting CDCP1 for proteasomal degradation

scientific article published on 04 July 2018

GalNAc-T14 promotes metastasis through Wnt dependent HOXB9 expression in lung adenocarcinoma

scientific article published on 26 October 2015

Generation of cancerous neural stem cells forming glial tumor by oncogenic stimulation.

scientific article

Genetic modification of human adipose-derived stem cells for promoting wound healing.

scientific article

Heat shock factor 1, an inhibitor of non-homologous end joining repair

scientific journal article

Helping Induced hPSCs Clean Up Their Act.

scientific article published in June 2017

Hepatitis B virus X protein activates the ATM-Chk2 pathway and delays cell cycle progression.

scientific article

Identification of a C-terminal region that regulates mitogen-activated protein kinase kinase-1 cytoplasmic localization and ERK activation

scientific article published on 16 October 2001

Identification of anti-melanogenic natural compounds from Galega officinalis and further drug repositioning

scientific article published on 16 March 2012

In situ label-free quantification of human pluripotent stem cells with electrochemical potential

scientific article published on 22 October 2015

Induction of MiR-21 by Stereotactic Body Radiotherapy Contributes to the Pulmonary Fibrotic Response.

scientific article

Induction of integrin β3 by sustained ERK activity promotes the invasiveness of TGFβ-induced mesenchymal tumor cells.

scientific article published on 13 April 2016

Inhibition of pluripotent stem cell-derived teratoma formation by small molecules ⬇️

scientific article published on August 5, 2013

Insulin concentration is critical in culturing human neural stem cells and neurons.

scientific article published on 08 August 2013

Intact wound repair activity of human mesenchymal stem cells after YM155 mediated selective ablation of undifferentiated human embryonic stem cells.

scientific article published on 31 January 2017

Large-scale pharmacogenomics based drug discovery for ITGB3 dependent chemoresistance in mesenchymal lung cancer

scholarly article by Soon-Ki Hong et al published 18 December 2018 in Molecular Cancer

Loss of E-cadherin activates EGFR-MEK/ERK signaling, which promotes invasion via the ZEB1/MMP2 axis in non-small cell lung cancer.

scientific article published on December 2013

Negative regulation of stress-induced matrix metalloproteinase-9 by Sirt1 in skin tissue.

scientific article

Nobiletin suppresses MMP-9 expression through modulation of p38 MAPK activity in human dermal fibrobalsts.

scientific article

Off-target response of a Wip1 chemical inhibitor in skin keratinocytes

scientific article published on 13 September 2013

Optimizing tissue-clearing conditions based on analysis of the critical factors affecting tissue-clearing procedures

scientific article published in Scientific Reports

PRMT8 Controls the Pluripotency and Mesodermal Fate of Human Embryonic Stem Cells By Enhancing the PI3K/AKT/SOX2 Axis.

scientific article published on 20 May 2017

Phosphorylation of golgin-160 by mixed lineage kinase 3.

scientific article

Phosphorylation regulates nucleophosmin targeting to the centrosome during mitosis as detected by cross-reactive phosphorylation-specific MKK1/MKK2 antibodies.

scientific article published on March 2004

Photodynamic Approach for Teratoma-Free Pluripotent Stem Cell Therapy Using CDy1 and Visible Light

scientific article published on 14 September 2016

Quercetin induced ROS production triggers mitochondrial cell death of human embryonic stem cells.

scientific article published on 5 August 2016

Regulation of the Wip1 phosphatase and its effects on the stress response.

scientific article

Repair of Ischemic Injury by Pluripotent Stem Cell Based Cell Therapy without Teratoma through Selective Photosensitivity

scientific article published on 11 November 2015

Requirement for phosphatidylinositol-3 kinase activity during progression through S-phase and entry into mitosis.

scientific article published in July 2003

Rh D blood group conversion using transcription activator-like effector nucleases

scientific article published on 16 June 2015

Role of MEK partner-1 in cancer stemness through MEK/ERK pathway in cancerous neural stem cells, expressing EGFRviii.

scientific article

SIRT1 is required for oncogenic transformation of neural stem cells and for the survival of "cancer cells with neural stemness" in a p53-dependent manner.

scientific article published on 5 August 2014

Screening of cytotoxic or cytostatic flavonoids with quantitative Fluorescent Ubiquitination-based Cell Cycle Indicator-based cell cycle assay

Selective Elimination of Culture-Adapted Human Embryonic Stem Cells with BH3 Mimetics

article

Senescent growth arrest in mesenchymal stem cells is bypassed by Wip1-mediated downregulation of intrinsic stress signaling pathways

scientific article published on August 2009

Sirt1 Regulates Microtubule Dynamics Through Negative Regulation of Plk1 in Mitosis.

scientific article published on 3 March 2015

Stochastic and Heterogeneous Cancer Cell Migration: Experiment and Theory

scientific article published on 08 November 2019

Suppression of SIRT2 and altered acetylation status of human pluripotent stem cells: possible link to metabolic switch during reprogramming

scientific article

TGFβ promotes YAP-dependent AXL induction in mesenchymal-type lung cancer cells

scientific article published on 18 November 2020

Technical approaches to induce selective cell death of pluripotent stem cells.

scientific article published on 28 February 2017

The accumulation of DNA repair defects is the molecular origin of carcinogenesis.

scientific article published on 02 August 2013

Timely Degradation of Wip1 Phosphatase by APC/C Activator Protein Cdh1 is Necessary for Normal Mitotic Progression

scientific article published on 01 August 2015

Tumor necrosis factor-inducible gene 6 promotes liver regeneration in mice with acute liver injury.

scientific article

Tumor necrosis factor-inducible gene 6 protein ameliorates chronic liver damage by promoting autophagy formation in mice.

scientific article published on 22 September 2017

Wip1 directly dephosphorylates gamma-H2AX and attenuates the DNA damage response

scientific article published on 11 May 2010

Wip1-expressing feeder cells retain pluripotency of co-cultured mouse embryonic stem cells under leukemia inhibitory factor-deprivated condition

scientific article published on 28 August 2010

Zap70 functions to maintain stemness of mouse embryonic stem cells by negatively regulating Jak1/Stat3/c-Myc signaling

scientific article

p16Ink4a suppression of lung adenocarcinoma by Bmi-1 in the presence of p38 activation.

scientific article

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