List of works - Philippe Brabet

A truncated form of rod photoreceptor PDE6 β-subunit causes autosomal dominant congenital stationary night blindness by interfering with the inhibitory activity of the γ-subunit

scientific article

Advanced late-onset retinitis pigmentosa with dominant-acting D477G RPE65 mutation is responsive to oral synthetic retinoid therapy

scientific article published on 05 May 2020

Altered social behavior in pituitary adenylate cyclase-activating polypeptide type I receptor-deficient mice.

scientific article published in October 2004

Anti-inflammatory role in septic shock of pituitary adenylate cyclase-activating polypeptide receptor.

scientific article

Apical localization of the alpha subunit of GTP-binding protein Go in choroidal and ciliated ependymocytes

scientific article

Bis-allylic Deuterated DHA Alleviates Oxidative Stress in Retinal Epithelial Cells

scientific article published on 01 October 2019

Caspase inhibitors, but not c-Jun NH2-terminal kinase inhibitor treatment, prevent cisplatin-induced hearing loss.

scientific article published in December 2004

Characterization of intestinal receptors for VIP and PACAP in rat and in PAC1 receptor knockout mouse

scientific article published on 01 January 2000

Deafness and cochlear fibrocyte alterations in mice deficient for the inner ear protein otospiralin.

scientific article

Disruption of the G(i2) alpha locus in embryonic stem cells and mice: a modified hit and run strategy with detection by a PCR dependent on gap repair.

scientific article

Dissociation between light-induced phase shift of the circadian rhythm and clock gene expression in mice lacking the pituitary adenylate cyclase activating polypeptide type 1 receptor.

scientific article

Fatp1 deficiency affects retinal light response and dark adaptation, and induces age-related alterations.

scientific article

Fatty acid transport protein 1 regulates retinoid metabolism and photoreceptor development in mouse retina.

scientific article

Gi2 alpha protein deficiency: a model of inflammatory bowel disease

scientific article published on 01 November 1995

Go, a major brain GTP binding protein in search of a function: purification, immunological and biochemical characteristics

scientific article published on April 1987

Granule cell survival is deficient in PAC1-/- mutant cerebellum.

scientific article published on 12 April 2008

Immunocytochemical localization of the guanine nucleotide-binding protein Go in primary cultures of neuronal and glial cells.

scientific article published in February 1988

Immunological localization of the GTP-binding protein Go in different tissues of vertebrates and invertebrates.

scientific article published in April 1987

Impaired somatodendritic responses to pituitary adenylate cyclase-activating polypeptide (PACAP) of supraoptic neurones in PACAP type I -receptor deficient mice.

scientific article published in September 2003

Inactivation of the G alpha i2 and G alpha o genes by homologous recombination.

scientific article published in January 1997

Induction of type I PACAP receptor expression by the new zinc finger protein Zac1 and p53

scientific article published on 01 December 1998

Isopropyl-phloroglucinol-DHA protects outer retinal cells against lethal dose of all-trans-retinal

scientific article published on 25 March 2020

Mice lacking the PACAP type I receptor have impaired photic entrainment and negative masking.

scientific article

Monoclonal antibodies obtained against G-protein epitopes: comparison of immunoreactions seen in the brain, retina and striated muscular tissue

scientific article published on 01 January 1991

Multiple neurological abnormalities in mice deficient in the G protein Go

scientific journal article

Mutations in IMPG1 cause vitelliform macular dystrophies.

scientific article published on 29 August 2013

Natural models for retinitis pigmentosa: progressive retinal atrophy in dog breeds

scientific article published on 23 March 2019

Nerve growth factor upregulates the PAC1 promoter by activating the MAP kinase pathway in rat PC12 cells

scientific article published on 01 January 2000

New Lipophenol Antioxidants Reduce Oxidative Damage in Retina Pigment Epithelial Cells

scientific article published on 19 December 2018

PAC1 null females display decreased fertility.

scientific article published in January 2000

PAC1 receptor-deficient mice display impaired insulinotropic response to glucose and reduced glucose tolerance.

scientific article

Phloroglucinol protects retinal pigment epithelium and photoreceptor against all-trans-retinal-induced toxicity and inhibits A2E formation

scientific article

Physiological and pathological roles of FATP-mediated lipid droplets in Drosophila and mice retina

scientific article published on 10 September 2018

Pituitary adenylate cyclase-activating polypeptide inhibits food intake in mice through activation of the hypothalamic melanocortin system.

scientific article published on 4 June 2008

Pituitary adenylate cyclase-activating polypeptide receptors mediating insulin secretion in rodent pancreatic islets are coupled to adenylate cyclase but not to PLC.

scientific article published in April 2002

Preclinical pharmacology of a lipophenol in a mouse model of light-induced retinopathy

scientific article published on 08 July 2020

Screening genes of the visual cycle RGR, RBP1 and RBP3 identifies rare sequence variations.

scientific article published on December 2010

Simple and efficient: validation of a cotton wick electrode for animal electroretinography

scientific article published on 04 November 2010

Structure and chromosomal localization of the human antidiuretic hormone receptor gene ⬇️

scientific article published on November 1, 1992

Targeting of the Gi2 alpha gene in ES cells with replacement and insertion vectors

scientific article published on January 1993

Transcription of the mouse PAC1 receptor gene: cell-specific expression and regulation by Zac1.

scientific article

Ulcerative colitis and adenocarcinoma of the colon in G alpha i2-deficient mice.

scientific article

Ultrastructural localization of the GTP-binding protein Go in neurons

scientific article (publication date: 1989)

VPAC2 receptors mediate vasoactive intestinal peptide-induced neuroprotection against neonatal excitotoxic brain lesions in mice.

scientific article

List of works by Philippe Brabet

A truncated form of rod photoreceptor PDE6 β-subunit causes autosomal dominant congenital stationary night blindness by interfering with the inhibitory activity of the γ-subunit

Advanced late-onset retinitis pigmentosa with dominant-acting D477G RPE65 mutation is responsive to oral synthetic retinoid therapy

Altered social behavior in pituitary adenylate cyclase-activating polypeptide type I receptor-deficient mice.

Anti-inflammatory role in septic shock of pituitary adenylate cyclase-activating polypeptide receptor.

Apical localization of the alpha subunit of GTP-binding protein Go in choroidal and ciliated ependymocytes

Bis-allylic Deuterated DHA Alleviates Oxidative Stress in Retinal Epithelial Cells

Caspase inhibitors, but not c-Jun NH2-terminal kinase inhibitor treatment, prevent cisplatin-induced hearing loss.

Characterization of intestinal receptors for VIP and PACAP in rat and in PAC1 receptor knockout mouse

Deafness and cochlear fibrocyte alterations in mice deficient for the inner ear protein otospiralin.

Disruption of the G(i2) alpha locus in embryonic stem cells and mice: a modified hit and run strategy with detection by a PCR dependent on gap repair.

Dissociation between light-induced phase shift of the circadian rhythm and clock gene expression in mice lacking the pituitary adenylate cyclase activating polypeptide type 1 receptor.

Fatp1 deficiency affects retinal light response and dark adaptation, and induces age-related alterations.

Fatty acid transport protein 1 regulates retinoid metabolism and photoreceptor development in mouse retina.

Gi2 alpha protein deficiency: a model of inflammatory bowel disease

Go, a major brain GTP binding protein in search of a function: purification, immunological and biochemical characteristics

Granule cell survival is deficient in PAC1-/- mutant cerebellum.

Immunocytochemical localization of the guanine nucleotide-binding protein Go in primary cultures of neuronal and glial cells.

Immunological localization of the GTP-binding protein Go in different tissues of vertebrates and invertebrates.

Impaired somatodendritic responses to pituitary adenylate cyclase-activating polypeptide (PACAP) of supraoptic neurones in PACAP type I -receptor deficient mice.

Inactivation of the G alpha i2 and G alpha o genes by homologous recombination.

Induction of type I PACAP receptor expression by the new zinc finger protein Zac1 and p53

Isopropyl-phloroglucinol-DHA protects outer retinal cells against lethal dose of all-trans-retinal

Mice lacking the PACAP type I receptor have impaired photic entrainment and negative masking.

Monoclonal antibodies obtained against G-protein epitopes: comparison of immunoreactions seen in the brain, retina and striated muscular tissue

Multiple neurological abnormalities in mice deficient in the G protein Go

Mutations in IMPG1 cause vitelliform macular dystrophies.

Natural models for retinitis pigmentosa: progressive retinal atrophy in dog breeds

Nerve growth factor upregulates the PAC1 promoter by activating the MAP kinase pathway in rat PC12 cells

New Lipophenol Antioxidants Reduce Oxidative Damage in Retina Pigment Epithelial Cells

PAC1 null females display decreased fertility.

PAC1 receptor-deficient mice display impaired insulinotropic response to glucose and reduced glucose tolerance.

Phloroglucinol protects retinal pigment epithelium and photoreceptor against all-trans-retinal-induced toxicity and inhibits A2E formation

Physiological and pathological roles of FATP-mediated lipid droplets in Drosophila and mice retina

Pituitary adenylate cyclase-activating polypeptide inhibits food intake in mice through activation of the hypothalamic melanocortin system.

Pituitary adenylate cyclase-activating polypeptide receptors mediating insulin secretion in rodent pancreatic islets are coupled to adenylate cyclase but not to PLC.

Preclinical pharmacology of a lipophenol in a mouse model of light-induced retinopathy

Screening genes of the visual cycle RGR, RBP1 and RBP3 identifies rare sequence variations.

Simple and efficient: validation of a cotton wick electrode for animal electroretinography

Structure and chromosomal localization of the human antidiuretic hormone receptor gene ⬇️

Targeting of the Gi2 alpha gene in ES cells with replacement and insertion vectors

Transcription of the mouse PAC1 receptor gene: cell-specific expression and regulation by Zac1.

Ulcerative colitis and adenocarcinoma of the colon in G alpha i2-deficient mice.

Ultrastructural localization of the GTP-binding protein Go in neurons

VPAC2 receptors mediate vasoactive intestinal peptide-induced neuroprotection against neonatal excitotoxic brain lesions in mice.