List of works - Giuseppe Floresta

3D-QSAR assisted identification of FABP4 inhibitors: An effective scaffold hopping analysis/QSAR evaluation

scientific article published on 29 November 2018

A Pseudouridine Isoxazolidinyl Nucleoside Analogue Structural Analysis: A Morphological Approach

A Rare Natural Benzo[k,l]xanthene as a Turn-Off Fluorescent Sensor for Cu2+ Ion

scientific article published on 21 September 2020

A Structure- and Ligand-Based Virtual Screening of a Database of "Small" Marine Natural Products for the Identification of "Blue" Sigma-2 Receptor Ligands

scientific article published on 14 October 2018

Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review.

scientific article

An Integrated Pharmacophore/Docking/3D-QSAR Approach to Screening a Large Library of Products in Search of Future Botulinum Neurotoxin A Inhibitors

scientific article published on 12 December 2020

Computational Tools in the Discovery of FABP4 Ligands: A Statistical and Molecular Modeling Approach

scientific article published on 31 October 2019

Cucurbit[7]uril as a catalytic nanoreactor for one-pot synthesis of isoxazolidines in water

scientific article published on 29 January 2020

DNA intercalators based on (1,10-phenanthrolin-2-yl)isoxazolidin-5-yl core with better growth inhibition and selectivity than cisplatin upon head and neck squamous cells carcinoma

scientific article published on 26 November 2017

Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis.

scientific article published on 29 May 2017

Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis

scientific article published on 27 August 2018

Discovery of High-Affinity Cannabinoid Receptors Ligands through a 3D-QSAR Ushered by Scaffold-Hopping Analysis

FABP4 inhibitors 3D-QSAR model and isosteric replacement of BMS309403 datasets

scientific article published on 19 December 2018

Fourfold Filtered Statistical/Computational Approach for the Identification of Imidazole Compounds as HO-1 Inhibitors from Natural Products

scientific article published on 12 February 2019

Functionalization of Single and Multi-Walled Carbon Nanotubes with Polypropylene Glycol Decorated Pyrrole for the Development of Doxorubicin Nano-Conveyors for Cancer Drug Delivery

scientific article published on 31 May 2020

Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands

scientific article published on 25 August 2017

Identification of potentially potent Heme Oxygenase-1 inhibitors through 3D-QSAR coupled to scaffold hopping analysis.

scientific article

Mild Friedel-Crafts Reactions inside a Hexameric Resorcinarene Capsule: C-Cl Bond Activation through Hydrogen Bonding to Bridging Water Molecules.

scientific article published on 13 March 2018

Molecular modeling studies of pseudouridine isoxazolidinyl nucleoside analogues as potential inhibitors of the pseudouridine 5'-monophosphate glycosidase

scientific article

Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands

scientific article published on 23 January 2019

New Arylethanolimidazole Derivatives as HO-1 Inhibitors with Cytotoxicity against MCF-7 Breast Cancer Cells

scientific article published on 11 March 2020

Novel Sigma-1 receptor antagonists: from opioids to small molecules: what is new?

scientific article published on 29 November 2017

Novel Structural Insight into Inhibitors of Heme Oxygenase-1 (HO-1) by New Imidazole-Based Compounds: Biochemical and In Vitro Anticancer Activity Evaluation

scientific article published on 18 May 2018

Physicochemical Characterization and Antioxidant Activity Evaluation of Idebenone/Hydroxypropyl-β-Cyclodextrin Inclusion Complex †

scientific article published on 25 September 2019

Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors

scientific article published on 9 February 2018

Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application

scientific article published on 12 February 2019

Sigma-2 receptor ligands QSAR model dataset

scientific article published on 16 June 2017

Structure-Based Approach for the Prediction of Mu-opioid Binding Affinity of Unclassified Designer Fentanyl-Like Molecules. ⬇️

scientific article published on 10 May 2019

Synergic Interplay Between Halogen Bonding and Hydrogen Bonding in the Activation of a Neutral Substrate in a Nanoconfined Space

scientific article published on 27 November 2019

Synthesis and evaluation of haloperidol metabolite II prodrugs as anticancer agents.

scientific article published on 4 September 2017

Synthesis of Rosmarinic Acid Amides as Antioxidative and Hypoglycemic Agents

scientific article published on 20 February 2019

Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines

scientific article published on 17 September 2018

The Search for Potent, Small-Molecule HDACIs in Cancer Treatment: A Decade After Vorinostat.

scientific article published on 9 February 2017

iVS analysis to evaluate the impact of scaffold diversity in the binding to cellular targets relevant in cancer ⬇️

scientific article published on 01 December 2019

γ-Cyclodextrin as a Catalyst for the Synthesis of 2-Methyl-3,5-diarylisoxazolidines in Water.

scientific article published on 13 April 2017

List of works by Giuseppe Floresta

3D-QSAR assisted identification of FABP4 inhibitors: An effective scaffold hopping analysis/QSAR evaluation

A Pseudouridine Isoxazolidinyl Nucleoside Analogue Structural Analysis: A Morphological Approach

A Rare Natural Benzo[k,l]xanthene as a Turn-Off Fluorescent Sensor for Cu2+ Ion

A Structure- and Ligand-Based Virtual Screening of a Database of "Small" Marine Natural Products for the Identification of "Blue" Sigma-2 Receptor Ligands

Adipocyte fatty acid binding protein 4 (FABP4) inhibitors. A comprehensive systematic review.

An Integrated Pharmacophore/Docking/3D-QSAR Approach to Screening a Large Library of Products in Search of Future Botulinum Neurotoxin A Inhibitors

Computational Tools in the Discovery of FABP4 Ligands: A Statistical and Molecular Modeling Approach

Cucurbit[7]uril as a catalytic nanoreactor for one-pot synthesis of isoxazolidines in water

DNA intercalators based on (1,10-phenanthrolin-2-yl)isoxazolidin-5-yl core with better growth inhibition and selectivity than cisplatin upon head and neck squamous cells carcinoma

Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis.

Development of new HO-1 inhibitors by a thorough scaffold-hopping analysis

Discovery of High-Affinity Cannabinoid Receptors Ligands through a 3D-QSAR Ushered by Scaffold-Hopping Analysis

FABP4 inhibitors 3D-QSAR model and isosteric replacement of BMS309403 datasets

Fourfold Filtered Statistical/Computational Approach for the Identification of Imidazole Compounds as HO-1 Inhibitors from Natural Products

Functionalization of Single and Multi-Walled Carbon Nanotubes with Polypropylene Glycol Decorated Pyrrole for the Development of Doxorubicin Nano-Conveyors for Cancer Drug Delivery

Hyphenated 3D-QSAR statistical model-scaffold hopping analysis for the identification of potentially potent and selective sigma-2 receptor ligands

Identification of potentially potent Heme Oxygenase-1 inhibitors through 3D-QSAR coupled to scaffold hopping analysis.

Mild Friedel-Crafts Reactions inside a Hexameric Resorcinarene Capsule: C-Cl Bond Activation through Hydrogen Bonding to Bridging Water Molecules.

Molecular modeling studies of pseudouridine isoxazolidinyl nucleoside analogues as potential inhibitors of the pseudouridine 5'-monophosphate glycosidase

Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands

New Arylethanolimidazole Derivatives as HO-1 Inhibitors with Cytotoxicity against MCF-7 Breast Cancer Cells

Novel Sigma-1 receptor antagonists: from opioids to small molecules: what is new?

Novel Structural Insight into Inhibitors of Heme Oxygenase-1 (HO-1) by New Imidazole-Based Compounds: Biochemical and In Vitro Anticancer Activity Evaluation

Physicochemical Characterization and Antioxidant Activity Evaluation of Idebenone/Hydroxypropyl-β-Cyclodextrin Inclusion Complex †

Potholing of the hydrophobic heme oxygenase-1 western region for the search of potent and selective imidazole-based inhibitors

Progress in the development of selective heme oxygenase-1 inhibitors and their potential therapeutic application

Sigma-2 receptor ligands QSAR model dataset

Structure-Based Approach for the Prediction of Mu-opioid Binding Affinity of Unclassified Designer Fentanyl-Like Molecules. ⬇️

Synergic Interplay Between Halogen Bonding and Hydrogen Bonding in the Activation of a Neutral Substrate in a Nanoconfined Space

Synthesis and evaluation of haloperidol metabolite II prodrugs as anticancer agents.

Synthesis of Rosmarinic Acid Amides as Antioxidative and Hypoglycemic Agents

Targeting heme Oxygenase-1 with hybrid compounds to overcome Imatinib resistance in chronic myeloid leukemia cell lines

The Search for Potent, Small-Molecule HDACIs in Cancer Treatment: A Decade After Vorinostat.

iVS analysis to evaluate the impact of scaffold diversity in the binding to cellular targets relevant in cancer ⬇️

γ-Cyclodextrin as a Catalyst for the Synthesis of 2-Methyl-3,5-diarylisoxazolidines in Water.