List of works - Leopold Parts

A Bayesian framework to account for complex non-genetic factors in gene expression levels greatly increases power in eQTL studies

scientific article

A high-definition view of functional genetic variation from natural yeast genomes

scientific article published on 14 January 2014

Accurate Classification of Protein Subcellular Localization from High-Throughput Microscopy Images Using Deep Learning

scientific article published on 8 April 2017

Accurate classification of protein subcellular localization from high throughput microscopy images using deep learning

scholarly article published 28 April 2016

Assessing the complex architecture of polygenic traits in diverged yeast populations

scientific article published on 25 January 2011

Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B.

scientific article published in March 2018

Binding of the integrated stress response inhibitor, ISRIB, reveals a regulatory site in the nucleotide exchange factor, eIF2B

Climate change at northern latitudes: rising atmospheric humidity decreases transpiration, N-uptake and growth rate of hybrid aspen

scientific article

Deep learning for computational biology

scientific article

Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures

scientific article

Evolution of genes and genomes on the Drosophila phylogeny

scientific article

Extent, causes, and consequences of small RNA expression variation in human adipose tissue

scientific article

Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes

scientific article

Gene expression changes with age in skin, adipose tissue, blood and brain

scientific article

Genetic Interaction Scoring Procedure for Bacterial Species

scientific article

Genome-wide mapping of cellular traits using yeast

scientific article

Heritability and genetic basis of protein level variation in an outbred population

scientific article

High-resolution mapping of complex traits with a four-parent advanced intercross yeast population.

scientific article published on 13 September 2013

Inferring genome-wide recombination landscapes from advanced intercross lines: application to yeast crosses.

scientific article

JACKS: joint analysis of CRISPR/Cas9 knock-out screens

JACKS: joint analysis of CRISPR/Cas9 knockout screens

article published in 2019

Joint genetic analysis of gene expression data with inferred cellular phenotypes

scientific article

Mapping cis- and trans-regulatory effects across multiple tissues in twins

scientific article published on 02 September 2012

Molecular phenotypes that are causal to complex traits can have low heritability and are expected to have small influence

Mutations generated by repair of Cas9-induced double strand breaks are predictable from surrounding sequence

No correlation between childhood maltreatment and telomere length

scientific article published on 3 August 2010

Pathway based factor analysis of gene expression data produces highly heritable phenotypes that associate with age

article

Pathway-based factor analysis of gene expression data produces highly heritable phenotypes that associate with age.

scientific article

Patterns of cis regulatory variation in diverse human populations

scientific article

Personalized medicine: from genotypes and molecular phenotypes towards therapy- session introduction

Population genomics of domestic and wild yeasts

scientific article

Powerful decomposition of complex traits in a diploid model

scientific article published on 2 November 2016

Powerful decomposition of complex traits in a diploid model using Phased Outbred Lines

Precise prediction of antibiotic resistance in Escherichia coli from full genome sequences

scholarly article published 4 June 2018

Predicting quantitative traits from genome and phenome with near perfect accuracy

scientific article published on 10 May 2016

Predicting quantitative traits from genome and phenome with near perfect accuracy

Predicting the mutations generated by repair of Cas9-induced double-strand breaks

Prediction of antibiotic resistance in Escherichia coli from large-scale pan-genome data

scholarly article by Danesh Moradigaravand et al published December 2018 in PLOS Computational Biology

Quantifying selection acting on a complex trait using allele frequency time series data.

scientific article

Quantitative CRISPR interference screens in yeast identify chemical-genetic interactions and new rules for guide RNA design

scientific article

Revealing the genetic structure of a trait by sequencing a population under selection

scientific article

SGAtools: one-stop analysis and visualization of array-based genetic interaction screens

scientific article published on 15 May 2013

SLING: a tool to search for linked genes in bacterial datasets

article

Segregating YKU80 and TLC1 alleles underlying natural variation in telomere properties in wild yeast

scientific article published on 18 September 2009

Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants

scientific article published on 13 October 2009

Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes

scientific article

The architecture of gene regulatory variation across multiple human tissues: the MuTHER study

scientific article

The genetic architecture of low-temperature adaptation in the wine yeast Saccharomyces cerevisiae

scientific article

The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis

scientific article

Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses

scientific article

gitter: a robust and accurate method for quantification of colony sizes from plate images

scientific article published on 20 March 2014

List of works by Leopold Parts

A Bayesian framework to account for complex non-genetic factors in gene expression levels greatly increases power in eQTL studies

A high-definition view of functional genetic variation from natural yeast genomes

Accurate Classification of Protein Subcellular Localization from High-Throughput Microscopy Images Using Deep Learning

Accurate classification of protein subcellular localization from high throughput microscopy images using deep learning

Assessing the complex architecture of polygenic traits in diverged yeast populations

Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B.

Binding of the integrated stress response inhibitor, ISRIB, reveals a regulatory site in the nucleotide exchange factor, eIF2B

Climate change at northern latitudes: rising atmospheric humidity decreases transpiration, N-uptake and growth rate of hybrid aspen

Deep learning for computational biology

Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures

Evolution of genes and genomes on the Drosophila phylogeny

Extent, causes, and consequences of small RNA expression variation in human adipose tissue

Functional Profiling of a Plasmodium Genome Reveals an Abundance of Essential Genes

Gene expression changes with age in skin, adipose tissue, blood and brain

Genetic Interaction Scoring Procedure for Bacterial Species

Genome-wide mapping of cellular traits using yeast

Heritability and genetic basis of protein level variation in an outbred population

High-resolution mapping of complex traits with a four-parent advanced intercross yeast population.

Inferring genome-wide recombination landscapes from advanced intercross lines: application to yeast crosses.

JACKS: joint analysis of CRISPR/Cas9 knock-out screens

JACKS: joint analysis of CRISPR/Cas9 knockout screens

Joint genetic analysis of gene expression data with inferred cellular phenotypes

Mapping cis- and trans-regulatory effects across multiple tissues in twins

Molecular phenotypes that are causal to complex traits can have low heritability and are expected to have small influence

Mutations generated by repair of Cas9-induced double strand breaks are predictable from surrounding sequence

No correlation between childhood maltreatment and telomere length

Pathway based factor analysis of gene expression data produces highly heritable phenotypes that associate with age

Pathway-based factor analysis of gene expression data produces highly heritable phenotypes that associate with age.

Patterns of cis regulatory variation in diverse human populations

Personalized medicine: from genotypes and molecular phenotypes towards therapy- session introduction

Population genomics of domestic and wild yeasts

Powerful decomposition of complex traits in a diploid model

Powerful decomposition of complex traits in a diploid model using Phased Outbred Lines

Precise prediction of antibiotic resistance in Escherichia coli from full genome sequences

Predicting quantitative traits from genome and phenome with near perfect accuracy

Predicting quantitative traits from genome and phenome with near perfect accuracy

Predicting the mutations generated by repair of Cas9-induced double-strand breaks

Prediction of antibiotic resistance in Escherichia coli from large-scale pan-genome data

Quantifying selection acting on a complex trait using allele frequency time series data.

Quantitative CRISPR interference screens in yeast identify chemical-genetic interactions and new rules for guide RNA design

Revealing the genetic structure of a trait by sequencing a population under selection

SGAtools: one-stop analysis and visualization of array-based genetic interaction screens

SLING: a tool to search for linked genes in bacterial datasets

Segregating YKU80 and TLC1 alleles underlying natural variation in telomere properties in wild yeast

Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants

Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes

The architecture of gene regulatory variation across multiple human tissues: the MuTHER study

The genetic architecture of low-temperature adaptation in the wine yeast Saccharomyces cerevisiae

The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis

Using probabilistic estimation of expression residuals (PEER) to obtain increased power and interpretability of gene expression analyses

gitter: a robust and accurate method for quantification of colony sizes from plate images