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List of works by Yoshimasa Takahashi

A SARS-CoV-2 antibody broadly neutralizes SARS-related coronaviruses and variants by coordinated recognition of a virus-vulnerable site

scientific article published on 24 August 2021

A humanized mouse model identifies key amino acids for low immunogenicity of H7N9 vaccines.

scientific article

A subcutaneously injected UV-inactivated SARS coronavirus vaccine elicits systemic humoral immunity in mice.

scientific article published on 16 August 2004

A unique nanoparticulate TLR9 agonist enables a HA split vaccine to confer FcγR-mediated protection against heterologous lethal influenza virus infection

scientific article published on 01 February 2019

Antibodies to a Conserved Influenza Head Interface Epitope Protect by an IgG Subtype-Dependent Mechanism

scientific article published on 01 May 2019

Antigen-receptor genes of the agnathan lamprey are assembled by a process involving copy choice.

scientific article

Autocrine B-cell stimulation by interleukin-2 during a cognate interaction with T-cells

scientific article published on 01 February 1999

Boosting of post-exposure human T-cell and B-cell recall responses in vivo by Burkholderia pseudomallei-related proteins

scientific article published on 9 January 2017

Both mutated and unmutated memory B cells accumulate mutations in the course of the secondary response and develop a new antibody repertoire optimally adapted to the secondary stimulus

scientific article published on 10 September 2013

CD22 expression mediates the regulatory functions of peritoneal B-1a cells during the remission phase of contact hypersensitivity reactions

scientific article published on 24 March 2010

Calibrating Hepatitis E Virus Serological Assays Using Asymptomatic Specimens Obtained in Japan

scientific article published in 2022

Development of an Inflammatory CD14<sup>+</sup> Dendritic Cell Subset in Humanized Mice

scientific article published on 15 March 2021

Distinct cellular pathways select germline-encoded and somatically mutated antibodies into immunological memory.

scientific article

Distinct germinal center selection at local sites shapes memory B cell response to viral escape

scientific article

EAF2 mediates germinal centre B-cell apoptosis to suppress excessive immune responses and prevent autoimmunity.

scientific article published on 3 March 2016

Efficient protection of mice from influenza A/H1N1pdm09 virus challenge infection via high avidity serum antibodies induced by booster immunizations with inactivated whole virus vaccine

Epitope mapping of the hemagglutinin molecule of A/(H1N1)pdm09 influenza virus by using monoclonal antibody escape mutants.

scientific article

Exposure of an occluded hemagglutinin epitope drives selection of a class of cross-protective influenza antibodies

scientific article published on 28 August 2019

Food antigen causes TH2-dependent enteropathy followed by tissue repair in T-cell receptor transgenic mice

scientific article published on 01 May 2006

Formalin-treated UV-inactivated SARS coronavirus vaccine retains its immunogenicity and promotes Th2-type immune responses.

scientific article published in May 2007

Germinal center-associated nuclear protein contributes to affinity maturation of B cell antigen receptor in T cell-dependent responses.

scholarly article

Immunological detection of severe acute respiratory syndrome coronavirus by monoclonal antibodies.

scientific article

In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. V. Affinity maturation develops in two stages of clonal selection.

scientific article published on March 1998

Influenza Antigen Engineering Focuses Immune Responses to a Subdominant but Broadly Protective Viral Epitope

scientific article published on 16 May 2019

Isotype-specific selection of high affinity memory B cells in nasal-associated lymphoid tissue

scientific article

Lack of antibody response to Guillain-Barré syndrome-related gangliosides in mice and men after novel flu vaccination

scientific article published on 07 November 2010

MHC class II/T-cell receptor interactions potentiate secretion of IgG but not IgM in response to T-dependent antigens ⬇️

scientific article published on April 1, 1998

MRC5 cells engineered to express ACE2 serve as a model system for the discovery of antivirals targeting SARS-CoV-2

scientific article published on 08 March 2021

Memory B cells in the lung participate in protective humoral immune responses to pulmonary influenza virus reinfection ⬇️

scientific article published on January 30, 2012

Metformin-induced suppression of IFN-α via mTORC1 signalling following seasonal vaccination is associated with impaired antibody responses in type 2 diabetes

scientific article published on 24 February 2020

Neutralization of hepatitis B virus with vaccine-escape mutations by hepatitis B vaccine with large-HBs antigen

scientific article published in 2022

Newly established monoclonal antibodies for immunological detection of H5N1 influenza virus.

scientific article published on January 2012

Novel role of the Ras cascade in memory B cell response.

scientific article

Oral administration of Lactobacillus plantarum strain AYA enhances IgA secretion and provides survival protection against influenza virus infection in mice

scientific article published on 22 January 2014

Protective neutralizing influenza antibody response in the absence of T follicular helper cells

scientific article

Regulated selection of germinal-center cells into the memory B cell compartment.

scientific article published on 9 May 2016

Sequential Sensing by TLR2 and Mincle Directs Immature Myeloid Cells to Protect against Invasive Group A Streptococcal Infection in Mice

scientific article published on 01 April 2019

Studies on the generation and maintenance of mucosal cytotoxic T lymphocytes against human immunodeficiency virus type 1 Gag in mice.

scientific article published in June 2003

Suppressive effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the high-affinity antibody response in C57BL/6 mice.

scientific article published on 28 May 2003

The direct cloning of the immunoglobulin VH genes from primary cultured B cells specific for a short peptide.

scientific article

Two waves of memory B-cell generation in the primary immune response.

scientific article published on 11 April 2005

Whole-Virion Influenza Vaccine Recalls an Early Burst of High-Affinity Memory B Cell Response through TLR Signaling

scientific article

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