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List of works by Alexander Khoruts

A causal link between lymphopenia and autoimmunity

scientific article

A pilot study of fecal bile acid and microbiota profiles in inflammatory bowel disease and primary sclerosing cholangitis

scientific article published on 10 January 2019

A role for CD28 in lymphopenia-induced proliferation of CD4 T cells

article

Analysis of gut microbiota - An ever changing landscape

scientific article

Antibiotic-induced Disruption of Intestinal Microbiota Contributes to Failure of Vertical Sleeve Gastrectomy

scientific article published on 8 March 2018

CD4+ T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

scientific article

CD4+CD25+Foxp3+ regulatory T cells optimize diversity of the conventional T cell repertoire during reconstitution from lymphopenia

scientific article published on 31 March 2010

Changes in Colonic Bile Acid Composition following Fecal Microbiota Transplantation Are Sufficient to Control Clostridium difficile Germination and Growth ⬇️

scientific article published on 20 January 2016

Changes in microbial ecology after fecal microbiota transplantation for recurrent C. difficile infection affected by underlying inflammatory bowel disease

scientific article

Changes in the composition of the human fecal microbiome after bacteriotherapy for recurrent Clostridium difficile-associated diarrhea

scientific article

Colonoscopic screening shows increased early incidence and progression of adenomas in cystic fibrosis

scientific article published on 2 February 2016

Competition for self ligands restrains homeostatic proliferation of naive CD4 T cells

scientific article

Cystic Fibrosis Colorectal Cancer Screening Consensus Recommendations

scientific article

De novo induction of antigen-specific CD4+CD25+Foxp3+ regulatory T cells in vivo following systemic antigen administration accompanied by blockade of mTOR.

scientific article

Defining total-body AIDS-virus burden with implications for curative strategies

scientific article published on 2 October 2017

Development of fecal microbiota transplantation suitable for mainstream medicine

scientific article

Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

scientific article published on 29 July 2008

Dynamic changes in short- and long-term bacterial composition following fecal microbiota transplantation for recurrent Clostridium difficile infection

scientific article published on 30 March 2015

Dysbiosis patterns during re-induction/salvage versus induction chemotherapy for acute leukemia

scientific article published on 15 April 2019

Early colon screening of adult patients with cystic fibrosis reveals high incidence of adenomatous colon polyps

scientific article

Effect of Fecal Microbiota Transplantation on Recurrence in Multiply Recurrent Clostridium difficile Infection: A Randomized Trial

scientific article

Emergence of fecal microbiota transplantation as an approach to repair disrupted microbial gut ecology

scientific article

Environmental Contamination in Households of Patients with Recurrent Clostridium difficile Infection

scientific article published on 26 February 2016

Faecal microbiota transplantation for Clostridioides difficile: mechanisms and pharmacology

scientific article published on 25 August 2020

Faecal microbiota transplantation in 2013: developing human gut microbiota as a class of therapeutics

scientific article

Faecal microbiota transplantation is promising but not a panacea

scholarly article by Michael J. Sadowsky & Alexander Khoruts published 24 February 2016 in Nature Microbiology

Fecal Microbiota Transplantation: Current Status in Treatment of GI and Liver Disease

scientific article published on 25 July 2018

Fecal microbiota transplantation and emerging applications

scientific article

Fecal microbiota transplantation-early steps on a long journey ahead

scientific article published on 10 April 2017

Fecal microbiota transplantation: an interview with alexander khoruts

scientific article

First microbial encounters

scientific article published in February 2016

From stool transplants to next-generation microbiota therapeutics

scientific article

Functional Genomics of Host-Microbiome Interactions in Humans

scientific article published on 26 October 2017

Guidance on preparing an investigational new drug application for fecal microbiota transplantation studies

scientific article

High-throughput DNA sequence analysis reveals stable engraftment of gut microbiota following transplantation of previously frozen fecal bacteria

scientific article

Human microbiome science: vision for the future, Bethesda, MD, July 24 to 26, 2013

scientific article

IL-1 acts on antigen-presenting cells to enhance the in vivo proliferation of antigen-stimulated naive CD4 T cells via a CD28-dependent mechanism that does not involve increased expression of CD28 ligands

scientific article published on April 2004

Induction of TGF-beta1 and TGF-beta1-dependent predominant Th17 differentiation by group A streptococcal infection

scientific article

Infection Followed by Graft-versus-Host Disease: Pathogenic Role of Antibiotics.

scientific article published on 28 February 2017

Inflammatory Bowel Disease Affects the Outcome of Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection

scientific article

Interaction of gut microbiota with bile acid metabolism and its influence on disease states

scientific article

Introduction to special issue on microbiome influences on host immunity

scientific article published on 12 August 2014

Is fecal microbiota transplantation a temporary patch for treatment of Clostridium difficile infection or a new frontier of therapeutics?

scientific article published on 18 April 2018

Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption

scientific article

Levaquin Gets a Pass

scientific article published on 20 December 2019

Lymphoid fibrosis occurs in long-term nonprogressors and persists with antiretroviral therapy but may be reversible with curative interventions

scientific article published on 24 October 2014

MHC class II deprivation impairs CD4 T cell motility and responsiveness to antigen-bearing dendritic cells in vivo

scientific article

Mast Cell Activation Disease and Microbiotic Interactions

scientific article published on 12 March 2015

Methanogen Abundance Thresholds Capable of Differentiating In Vitro Methane Production in Human Stool Samples

scientific article published on 28 November 2020

Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study

scientific article published on 23 January 2017

Microbiota changes and intestinal microbiota transplantation in liver diseases and cirrhosis

scientific article published on 28 January 2020

Microbiota transplantation restores normal fecal bile acid composition in recurrent Clostridium difficile infection

scientific article

Naive and memory CD4+ T cell survival controlled by clonal abundance

scientific article published on 02 March 2006

Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues

scientific article published on 27 January 2014

Regulatory CD4+CD25+Foxp3+ T cells selectively inhibit the spontaneous form of lymphopenia-induced proliferation of naive T cells.

scientific article published in June 2008

Reply

Resolution of severe Clostridium difficile infection following sequential fecal microbiota transplantation

scientific article published on September 2013

Sleeve gastrectomy drives persistent shifts in the gut microbiome

scientific article published on 4 January 2017

Stable engraftment of human microbiota into mice with a single oral gavage following antibiotic conditioning.

scientific article published on August 2017

Standardized frozen preparation for transplantation of fecal microbiota for recurrent Clostridium difficile infection

scientific article

Strain Tracking Reveals the Determinants of Bacterial Engraftment in the Human Gut Following Fecal Microbiota Transplantation

scientific article published in February 2018

Synthesis and Biological Evaluation of Bile Acid Analogues Inhibitory to Clostridium difficile Spore Germination

scientific article

Targeting the microbiome: from probiotics to fecal microbiota transplantation

scientific article published on 30 October 2018

Toward revision of antimicrobial therapies in hematopoietic stem cell transplantation: target the pathogens, but protect the indigenous microbiota.

scientific article

Treating Clostridium difficile infection with fecal microbiota transplantation

scientific article

Treatment of recurrent Clostridium difficile infection using fecal microbiota transplantation in patients with inflammatory bowel disease

scientific article published on 19 January 2017

Understanding the mechanisms of faecal microbiota transplantation

scientific article

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