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List of works by Jennifer Nichols

8C-like cells capture the human zygotic genome activation program in vitro

publication published on 24 February 2022

A SNP in the Immunoregulatory Molecule CTLA-4 Controls mRNA Splicing In Vivo but Does Not Alter Diabetes Susceptibility in the NOD Mouse

scientific article

A Sprouty4 reporter to monitor FGF/ERK signaling activity in ESCs and mice

scientific article published on 30 June 2018

A conserved Oct4/POUV-dependent network links adhesion and migration to progenitor maintenance

scientific article

A lncRNA fine tunes the dynamics of a cell state transition involving Lin28, let-7 and de novo DNA methylation

scientific article published on 18 August 2017

A molecular basis for developmental plasticity in early mammalian embryos ⬇️

scientific article published on September 1, 2013

A practical and efficient cellular substrate for the generation of induced pluripotent stem cells from adults: blood-derived endothelial progenitor cells

scientific article

A single-cell molecular map of mouse gastrulation and early organogenesis

scientific article published on 20 February 2019

Acute loss of Cited2 impairs Nanog expression and decreases self-renewal of mouse embryonic stem cells

scientific article

Alpha-fetoprotein, the major fetal serum protein, is not essential for embryonic development but is required for female fertility.

scientific article

An international analysis of contact lens compliance.

scientific article published on 24 August 2011

Cell signalling regulates dynamics of Nanog distribution in embryonic stem cell populations ⬇️

scientific article published on November 8, 2012

Changing potency by spontaneous fusion.

scientific article published on 13 March 2002

Correction: Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human pre-implantation epiblast (doi: 10.1242/dev.158501)

scholarly article by Giuliano G Stirparo published in August 2018

Defined conditions for propagation and manipulation of mouse embryonic stem cells

scientific article published on 26 March 2019

Defining Lineage Potential and Fate Behavior of Precursors during Pancreas Development

article

Defining murine organogenesis at single-cell resolution reveals a role for the leukotriene pathway in regulating blood progenitor formation.

scientific article published on 8 January 2018

Derivation and propagation of embryonic stem cells in serum- and feeder-free culture.

scientific article published in January 2006

Derivation of Mouse Embryonic Stem (ES) Cell Lines Using Small-Molecule Inhibitors of Erk and Gsk3 Signaling (2i).

scientific article published in May 2017

Derivation of germline competent embryonic stem cells with a combination of interleukin-6 and soluble interleukin-6 receptor

scientific article published on 01 November 1994

Embryonic germ cells from mice and rats exhibit properties consistent with a generic pluripotent ground state.

scientific article

Embryonic stem cells and transgenic mice ubiquitously expressing a tau-tagged green fluorescent protein.

scientific article published in December 2000

Esrrb Complementation Rescues Development of Nanog-Null Germ Cells

scientific article published in January 2018

Exit from Naive Pluripotency Induces a Transient X Chromosome Inactivation-like State in Males.

scientific article

Exit from Pluripotency Is Gated by Intracellular Redistribution of the bHLH Transcription Factor Tfe3 ⬇️

scientific article published on April 11, 2013

Expression of alternative forms of differentiation inhibiting activity (DIA/LIF) during murine embryogenesis and in neonatal and adult tissues.

scientific article published in January 1993

Genome-Scale Oscillations in DNA Methylation during Exit from Pluripotency

scientific article published on 01 July 2018

Germline potential of parthenogenetic haploid mouse embryonic stem cells.

scientific article

Human hypoblast formation is not dependent on FGF signalling.

scientific article

Hydrogel contact lens binding induced by contact lens rewetting drops.

scientific article

Imaging and measurement in the eye: now and ahead

scientific article published on 01 May 2012

Impact of a rinse step on protein removal from silicone hydrogel contact lenses.

scientific article

Integrated analysis of single-cell embryo data yields a unified transcriptome signature for the human preimplantation epiblast

scientific article

International rigid contact lens prescribing.

scientific article

Isolation and propagation of enteric neural crest progenitor cells from mouse embryonic stem cells and embryos

scientific article

Klf4 reverts developmentally programmed restriction of ground state pluripotency

scientific article

Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar.

scientific article published in April 2004

LIF-independent JAK signalling to chromatin in embryonic stem cells uncovered from an adult stem cell disease

scientific article

Lineage-Specific Profiling Delineates the Emergence and Progression of Naive Pluripotency in Mammalian Embryogenesis

scientific article

Long-term contact lens wear of children and teens.

scientific article published in July 2013

Loss of Wnt8b has no overt effect on hippocampus development but leads to altered Wnt gene expression levels in dorsomedial telencephalon

scientific journal article

Maximizing Clonal Embryonic Stem Cell Derivation by ERK Pathway Inhibition.

scientific article

Mbd3, a component of the NuRD co-repressor complex, is required for development of pluripotent cells

scientific journal article

Metabolic control of DNA methylation in naive pluripotent cells

scientific article published on 01 February 2021

Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning

scientific article published on 7 February 2018

NANOG amplifies STAT3 activation and they synergistically induce the naive pluripotent program

scientific article

Naive Pluripotent Stem Cells Derived Directly from Isolated Cells of the Human Inner Cell Mass

scientific article published on 27 February 2016

Nanog is the gateway to the pluripotent ground state.

scientific article

Nanog retrotransposed genes with functionally conserved open reading frames.

scientific article published on 14 July 2006

Nanog safeguards pluripotency and mediates germline development

scientific article (publication date: 20 December 2007)

Oct4 and LIF/Stat3 additively induce Krüppel factors to sustain embryonic stem cell self-renewal

scientific article published in December 2009

Oct4 is required for lineage priming in the developing inner cell mass of the mouse blastocyst.

scientific article published on 06 February 2014

Oct4 regulates the embryonic axis and coordinates exit from pluripotency and germ layer specification in the mouse embryo

scientific article published on 18 June 2018

Over the counter (OTC) artificial tear drops for dry eye syndrome

scientific article

Overcoming self-destruction in the pancreas.

scientific article published on 24 October 2009

Parameters influencing derivation of embryonic stem cells from murine embryos

scientific article published on 01 December 2008

Pluripotency in the embryo and in culture

scientific article

Primate embryogenesis predicts the hallmarks of human naïve pluripotency.

scientific article

Promotion of reprogramming to ground state pluripotency by signal inhibition

scientific article

Rebuilding pluripotency from primordial germ cells

scientific article published on 04 June 2013

Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells

scientific article

Reliability of grading lissamine green conjunctival staining.

scientific article

Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human

scientific article published on 16 July 2015

Resetting transcription factor control circuitry toward ground-state pluripotency in human

scientific article

Selection and dynamics of embryonic stem cell integration into early mouse embryos

scientific article published on 19 November 2015

Single cell transcriptome analysis of human, marmoset and mouse embryos reveals common and divergent features of preimplantation development

article

Single-Cell Landscape of Transcriptional Heterogeneity and Cell Fate Decisions during Mouse Early Gastrulation

scientific article published on August 2017

Single-cell transcriptome analysis of human, marmoset and mouse embryos reveals common and divergent features of preimplantation development

article

States and Origins of Mammalian Embryonic Pluripotency In Vivo and in a Dish

scientific article published on 06 December 2017

Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo.

scientific article published on 26 August 2009

The BAF and PRC2 Complex Subunits Dpf2 and Eed Antagonistically Converge on Tbx3 to Control ESC Differentiation

The NuRD component Mbd3 is required for pluripotency of embryonic stem cells

scientific journal article

The POU-er of gene nomenclature.

scientific article

The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate

scientific article published on December 2011

The Stat6-regulated KRAB domain zinc finger protein Zfp157 regulates the balance of lineages in mammary glands and compensates for loss of Gata-3

scientific journal article

The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification

scientific article (publication date: June 2014)

The birth of embryonic pluripotency.

scientific article

The germ cell determinant Blimp1 is not required for derivation of pluripotent stem cells

scientific article

The impact of hydrogel lens settling on the thickness of the tears and contact lens.

scientific article published in August 2004

The many faces of Pluripotency: in vitro adaptations of a continuum of in vivo states

scientific article

The neurobiology of the meibomian glands.

scientific article published on 15 April 2014

The nonconventional MHC class II molecule DM governs diabetes susceptibility in NOD mice

scientific article

The opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis

scientific article published on 20 November 2011

The transcriptional and epigenomic foundations of ground state pluripotency.

scientific article

Totipotent embryonic stem cells arise in ground-state culture conditions.

scientific article

Tracking the embryonic stem cell transition from ground state pluripotency

scientific article

Transgenic systems in nuclear reprogramming.

scientific article published on January 2006

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