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List of works by Renaud Mahieux

A 10-amino acid domain within human T-cell leukemia virus type 1 and type 2 tax protein sequences is responsible for their divergent subcellular distribution

scientific article published on 21 July 2004

A Transgenic Drosophila melanogaster Model To Study Human T-Lymphotropic Virus Oncoprotein Tax-1-Driven Transformation In Vivo

scientific article published on 20 May 2015

A transgenic Drosophila melanogaster model to study HTLV-I oncoprotein Tax-driven leukemogenesis in vivo

scientific article published on 28 August 2015

A vaccine against HTLV-1 HBZ makes sense

scientific article published on August 2015

A virus called HTLV-1. Epidemiological aspects

scientific article

ADAR1 enhances HTLV-1 and HTLV-2 replication through inhibition of PKR activity

scientific article published on 12 November 2014

APH-2 and Tax expression are correlated with a HTLV-2 proviral load but not with lymphocytosis

scientific article published on 6 June 2011

Adult T-cell leukemia/lymphoma and HTLV-1.

scientific article published on October 2007

Alpha interferon restricts human T-lymphotropic virus type 1 and 2 de novo infection through PKR activation.

scientific article published on 2 October 2013

Anti-HTLV antibody profiling reveals an antibody signature for HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP).

scientific article published on 20 October 2008

Antisense protein of HTLV-2 (APH-2) associates with PML nuclear bodies: molecular determinants and functional implications

scientific article published on 7 January 2014

Arsenic trioxide induces apoptosis in human T-cell leukemia virus type 1– and type 2–infected cells by a caspase-3–dependent mechanism involving Bcl-2 cleavage ⬇️

scientific article published on December 15, 2001

Biological evaluation of substituted quinolines

scientific article published on July 2004

Cell cycle regulation of human interleukin-8 gene expression by the human immunodeficiency virus type 1 Tat protein.

scientific article

Cell-Free versus Cell-to-Cell Infection by Human Immunodeficiency Virus Type 1 and Human T-Lymphotropic Virus Type 1: Exploring the Link among Viral Source, Viral Trafficking, and Viral Replication.

scientific article published on 22 June 2016

Centrosome and retroviruses: the dangerous liaisons

scientific article published on 14 April 2007

Combination of arsenic and interferon-α inhibits expression of KSHV latent transcripts and synergistically improves survival of mice with primary effusion lymphomas

scientific article

Comparative infection of autologous primary T cells and monocytes derived DCs using cell-free virus preparation, viral biofilm, pseudotyped-virus or viral synapse.

scientific article

Complete Genome Sequence of a Papio anubis Simian Foamy Provirus

scientific article published on 03 October 2019

Complete sequence of a novel highly divergent simian T-cell lymphotropic virus from wild-caught red-capped mangabeys (Cercocebus torquatus) from Cameroon: a new primate T-lymphotropic virus type 3 subtype

scientific article

Conference highlights of the 15th International Conference on Human Retrovirology: HTLV and related retroviruses, 4-8 June 2011, Leuven, Gembloux, Belgium

scientific article published on 28 October 2011

Construction and characterization of a full-length infectious simian T-cell lymphotropic virus type 3 molecular clone

scientific article published on 11 April 2007

Construction and characterization of a human T-cell lymphotropic virus type 3 infectious molecular clone

scientific article

Cooperation of NF-kappaB2/p100 activation and the PDZ domain binding motif signal in human T-cell leukemia virus type 1 (HTLV-1) Tax1 but not HTLV-2 Tax2 is crucial for interleukin-2-independent growth transformation of a T-cell line

scientific article published on 22 August 2007

Cutting edge: a short polypeptide domain of HIV-1-Tat protein mediates pathogenesis.

scientific article published in July 1999

Cytokine Networks Dysregulation during HTLV-1 Infection and Associated Diseases

scientific article published on 05 December 2018

Demographic, ethnic, and geographic differences between human T cell lymphotropic virus (HTLV) type I-seropositive carriers and persons with HTLV-I Gag-indeterminate Western blots in Central Africa.

scientific article published on August 1997

Dendritic cell maturation, but not type I interferon exposure, restricts infection by HTLV-1, and viral transmission to T-cells.

scientific article

Detection and quantification of STLV-1 and SFV proviral load in blood and saliva of naturally infected non-human primates

scientific article

Direct detection of diverse metabolic changes in virally transformed and Tax-expressing cells by mass spectrometry.

scientific article published on 6 June 2011

Direct detection of diverse metabolic changes in virally transformed and tax-expressing cells by mass spectrometry

scientific article

Discovery and characterization of auxiliary proteins encoded by type 3 simian T-cell lymphotropic viruses

scientific article

Discovery of a new human T-cell lymphotropic virus (HTLV-3) in Central Africa

scientific article

Distinct Contributions of Autophagy Receptors in Measles Virus Replication

scientific article

Distinct DC subsets are not equally susceptible to HTLV-1 infection.

scientific article published on 7 January 2014

Double-stranded RNA adenosine deaminase ADAR1 enhances both T cell susceptibility to human T-cell leukemia virus type 1 and 2 and viral replication

scientific article published on 7 January 2014

Epidemiology, origin and genetic diversity of HTLV-1 retrovirus and STLV-1 simian affiliated retrovirus

scientific article published in July 2000

Exclusion from the Golgi and very low levels of HTLV-2 Tax ubiquitination do not prevent IKK-gamma/NEMO relocalization and NF-κB activation

scholarly article by Chloé Journo et al published 2011 in Retrovirology

Exosomes derived from HTLV-1 infected cells contain viral proteins and mRNA.

scientific article published on 28 August 2015

Extensive editing of a small fraction of human T-cell leukemia virus type 1 genomes by four APOBEC3 cytidine deaminases

scientific article

Forefront studies on HTLV-1 oncogenesis

scientific article published on 18 June 2013

Functional analysis of the relationship between Vpx and the restriction factor SAMHD1.

scientific article

Gem-induced cytoskeleton remodeling increases cellular migration of HTLV-1-infected cells, formation of infected-to-target T-cell conjugates and viral transmission

scientific article

HIV genetic variation is directed and restricted by DNA precursor availability.

scientific article published on July 1997

HTLV gene regulation: because size matters, transcription is not enough

scientific article published on May 2009

HTLV-1 Extracellular Vesicles Promote Cell-to-Cell Contact

scientific article published on 18 September 2019

HTLV-1 Tax targets centrosomal Cep63 protein

scientific article

HTLV-1 and Innate Immunity ⬇️

scientific article published on August 8, 2011

HTLV-1 and associated adult T-cell leukemia/lymphoma.

scientific article published on December 2003

HTLV-1 and dendritic cells: a relation-ship in search of maturation

scientific article published on 16 February 2018

HTLV-1 infection of myeloid cells: from transmission to immune alterations

scientific article published on 23 December 2019

HTLV-1, the Other Pathogenic Yet Neglected Human Retrovirus: From Transmission to Therapeutic Treatment

scientific article published on 21 December 2017

HTLV-1-induced leukotriene B4 secretion by T cells promotes T cell recruitment and virus propagation

scientific article

HTLV-2 APH-2 expression is correlated with proviral load but APH-2 does not promote lymphocytosis

scientific article published on 7 November 2011

HTLV-2 in Central Africa: HTLV-2 subtype B strains similar to those found in Amerindian tribes are endemic in Bakola Pygmies from south Cameroon but not in surrounding Bantus and Baka Pygmies

scientific article published on 6 June 2011

HTLV-2B strains, similar to those found in several Amerindian tribes, are endemic in central African Bakola Pygmies

scientific article published in May 2011

HTLV-3/4 and simian foamy retroviruses in humans: discovery, epidemiology, cross-species transmission and molecular virology

scientific article

HTLV-3/STLV-3 and HTLV-4 viruses: discovery, epidemiology, serology and molecular aspects

scientific article

HTLV-I, Tax: fox hunting still allowed.

scientific article published in June 2008

Highly active antiretroviral treatment against STLV-1 infection combining reverse transcriptase and HDAC inhibitors.

scientific article

How to Control HTLV-1-Associated Diseases: Preventing de Novo Cellular Infection Using Antiviral Therapy.

scientific article

Human T cell leukemia virus type 2 tax-mediated NF-κB activation involves a mechanism independent of Tax conjugation to ubiquitin and SUMO.

scientific article published on 7 November 2012

Human T-cell leukemia virus type 1 (HTLV-1) Tax oncoprotein induces DNA damages through Activation-Induced cytidine Deaminase (AID).

scientific article published on 7 January 2014

Human T-cell leukemia virus type 2 produces a spliced antisense transcript encoding a protein that lacks a classic bZIP domain but still inhibits Tax2-mediated transcription

scientific article published on 14 July 2009

Human T-cell leukemia virus type-1 Tax oncoprotein regulates G-protein signaling

scientific article published on 21 September 2006

Human T-cell lymphotropic virus type 3: complete nucleotide sequence and characterization of the human tax3 protein

scientific article

Human T-lymphotropic virus type 1-infected cells secrete exosomes that contain Tax protein

scientific article

Human T-lymphotropic virus type I Tax protein utilizes distinct pathways for p53 inhibition that are cell type-dependent.

scientific article

Hyperediting of human T-cell leukemia virus type 2 and simian T-cell leukemia virus type 3 by the dsRNA adenosine deaminase ADAR-1.

scientific article published on 19 September 2012

IFITM proteins are incorporated onto HIV-1 virion particles and negatively imprint their infectivity

scientific article published on 25 November 2014

Identification and characterization of auxiliary proteins encoded by the STLV-3 retrovirus pX region

Identification of Modulators of HIV-1 Proviral Transcription from a Library of FDA-Approved Pharmaceuticals

scientific article published on 23 September 2020

Immunological changes and cytokine gene expression during primary infection with human T-cell leukaemia virus type 1 in squirrel monkeys (Saimiri sciureus).

scientific article published on 16 January 2007

In primary effusion lymphoma cells, MYB transcriptional repression is associated with v-FLIP expression during latent KSHV infection while both v-FLIP and v-GPCR become involved during the lytic cycle

scientific article

In vivo and in vitro treatment of HTLV-1 and HTLV-2 infected cells with arsenic trioxide and interferon-alpha

scientific article

Inactivation of p53 by human T-cell lymphotropic virus type 1 Tax requires activation of the NF-kappaB pathway and is dependent on p53 phosphorylation.

scientific article

Inhibition of HTLV-1 transcription by cyclin dependent kinase inhibitors

scientific article published on August 2002

Intercellular transmission of HTLV-1: not all mechanisms have been revealed

scientific article published on June 2015

Localization and sub-cellular shuttling of HTLV-1 Tax with the microRNA machinery.

scientific article

Localization and sub-cellular shuttling of HTLV-1 tax with the miRNA machinery

scientific article

Low levels of HTLV-2 Tax conjugation to ubiquitin and SUMO do not impede Tax-mediated activation of NF-κB.

scientific article published on 7 January 2014

Low nuclear body formation and tax SUMOylation do not prevent NF-kappaB promoter activation

scientific article

Lyon, a critical place for performing Virology research

scientific article published on 01 March 2019

Molecular Epidemiology of HTLV-II among United States Blood Donors and Intravenous Drug Users: An Age–Cohort Effect for HTLV-II RFLP Type a0 ⬇️

scientific article published on March 15, 1998

Molecular characterization and phylogenetic analyses of a new, highly divergent simian T-cell lymphotropic virus type 1 (STLV-1marc1) in Macaca arctoides ⬇️

scientific article published on August 1, 1997

Molecular epidemiology of 58 new African human T-cell leukemia virus type 1 (HTLV-1) strains: identification of a new and distinct HTLV-1 molecular subtype in Central Africa and in Pygmies.

scientific article published in February 1997

Multiple retroviral infection by HTLV type 1, 2, 3 and simian foamy virus in a family of Pygmies from Cameroon

scientific article published on 18 November 2010

NRP/Optineurin Cooperates with TAX1BP1 to potentiate the activation of NF-kappaB by human T-lymphotropic virus type 1 tax protein

scientific article

New strain of human T lymphotropic virus (HTLV) type 3 in a Pygmy from Cameroon with peculiar HTLV serologic results

scientific article

Origin of HTLV-1 in hunters of nonhuman primates in Central Africa

scientific article

P53 facilitates degradation of human T-cell leukaemia virus type I Tax-binding protein through a proteasome-dependent pathway

scientific article

Predominant role of Tax sumoylation in Tax-induced NF-kB activation in T cells.

scientific article

Preexisting infection with human T-cell lymphotropic virus type 2 neither exacerbates nor attenuates simian immunodeficiency virus SIVmac251 infection in macaques

scientific article

Presence of a functional but dispensable nuclear export signal in the HTLV-2 Tax protein

scientific article

Quantifying transmission by stage of infection in the field: the example of SIV-1 and STLV-1 infecting mandrills

scientific article published on 8 October 2014

Quantitative Analysis of Human T-Lymphotropic Virus Type 1 (HTLV-1) Infection Using Co-Culture with Jurkat LTR-Luciferase or Jurkat LTR-GFP Reporter Cells.

scientific article published on January 2017

Reducing the global burden of HTLV-1 infection: An agenda for research and action

scientific article

SQSTM-1/p62 potentiates HTLV-1 Tax-mediated NF-κB activation through its ubiquitin binding function

scientific article published on 05 November 2019

SQSTM1/p62 regulates HTLV-1 tax mediated NF-κB activation

scientific article published on 28 August 2015

STLV-1 as a model for studying HTLV-1 infection

scientific article published on 16 December 2019

STLV-1 co-infection is correlated with an increased SFV proviral load in the peripheral blood of SFV/STLV-1 naturally infected non-human primates

scientific article

Sensing of cell-associated HTLV by plasmacytoid dendritic cells is regulated by dense β-galactoside glycosylation

scientific article published on 28 February 2019

Seroepidemiology, viral isolation, and molecular characterization of human T cell leukemia/lymphoma virus type I from La Réunion Island, Indian Ocean.

scientific article published on June 1994

Stability of HTLV-2 antisense protein is controlled by PML nuclear bodies in a SUMO-dependent manner

scientific article

Studies on quinones. Part 37. Synthesis and biological activity of o-aminoester functionalised benzo- and naphtho[2,3-b]thiophenequinones

scientific article published on September 2002

Substituted quinolines induce inhibition of proliferation of HTLV-1 infected cells

scientific article published on March 2003

TRAF3 Is Required for NF-κB Pathway Activation Mediated by HTLV Tax Proteins

scientific article published on 12 June 2019

TRAF5-mediated Tax ubiquitination modulates IKK phosphorylation but not binding to NEMO.

scientific article published on 7 January 2014

Tailored HIV-1 vectors for genetic modification of primary human dendritic cells and monocytes

scientific article published on 17 October 2012

Tax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cells

scientific article

Tax protein-induced expression of antiapoptotic Bfl-1 protein contributes to survival of human T-cell leukemia virus type 1 (HTLV-1)-infected T-cells.

scientific article published in October 2012

Tax ubiquitylation and sumoylation control critical cytoplasmic and nuclear steps of NF-kappaB activation

scientific article

The HTLV-I Tax oncoprotein targets the retinoblastoma protein for proteasomal degradation

scientific article

The antisense protein of HTLV-2 positively modulates HIV-1 replication

scientific article published on 7 January 2014

The double antiviral effect of IFITM is conserved in many species of enveloped viruses

scientific article

The efficacy of combined therapy of arsenic trioxide and alpha interferon in human T-cell leukemia virus type-1-infected squirrel monkeys (Saimiri sciureus).

scientific article published on 28 February 2006

The interferon stimulated gene 20 protein (ISG20) is an innate defense antiviral factor that discriminates self versus non-self translation

scientific article published on 10 October 2019

The multifaceted oncoprotein Tax: subcellular localization, posttranslational modifications, and NF-κB activation

scientific article published on January 2012

The receptor complex associated with human T-cell lymphotropic virus type 3 (HTLV-3) Env-mediated binding and entry is distinct from, but overlaps with, the receptor complexes of HTLV-1 and HTLV-2.

scientific article published on 11 March 2009

The tax mutation at nucleotide 7959 of human T-cell leukemia virus type 1 (HTLV-1) is not associated with tropical spastic paraparesis/HTLV-1-associated myelopathy but is linked to the cosmopolitan molecular genotype.

scientific article published on September 1995

The transcription profile of Tax-3 is more similar to Tax-1 than Tax-2: insights into HTLV-3 potential leukemogenic properties

scientific article

Transcriptomic analyses reveal that the cellular Gem protein promotes HTLV-1 infected cell migration and viral transmission.

scientific article published on 7 January 2014

Treatment of an aggressive STLV-1 associated lymphoma in a naturally infected baboon.

scientific article

Tropical spastic paraparesis and HTLV-1 associated myelopathy: Clinical, epidemiological, virological and therapeutic aspects ⬇️

scientific article published on March 7, 2012

Utilization of the CBP but not the p300 co-activator by human T-lymphotropic virus type-2 Tax for p53 inhibition

scientific article published in July 2004

Viral Source-Independent High Susceptibility of Dendritic Cells to Human T-Cell Leukemia Virus Type 1 Infection Compared to That of T Lymphocytes.

scientific article published on 12 August 2015

Whole body clonality analysis in an aggressive STLV-1 associated leukemia (ATLL) reveals an unexpected clonal complexity

scientific article published on 26 December 2016

[Unanchored ubiquitin chains: a new viral target for NF-κB activation].

scientific article

[Virological aspects of HTLV-1 infection and new therapeutical concepts].

scientific article published on 23 May 2011

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