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List of works by David C Spray

A developmental switch in the expression of aquaporin-4 and Kir4.1 from horizontal to Müller cells in mouse retina.

scientific article published in October 2005

A stochastic two-dimensional model of intercellular Ca2+ wave spread in glia.

scientific article

ATP signaling is deficient in cultured Pannexin1-null mouse astrocytes

scientific article

Acquired infection with Toxoplasma gondii in adult mice results in sensorimotor deficits but normal cognitive behavior despite widespread brain pathology.

scientific article

Activation of a voltage-insensitive conductance by inward calcium current ⬇️

scientific article published on July 31, 1975

Acute downregulation of Cx43 alters P2Y receptor expression levels in mouse spinal cord astrocytes

scientific article published on April 2003

Adipocytes in both brown and white adipose tissue of adult mice are functionally connected via gap junctions: implications for Chagas disease

scientific article

Alteration of transcriptomic networks in adoptive-transfer experimental autoimmune encephalomyelitis

scientific article published on 30 December 2007

Alterations in myocardial gene expression associated with experimental Trypanosoma cruzi infection

scientific article published on 17 March 2008

Alterations in the Brain Transcriptome in Plasmodium Berghei ANKA Infected Mice.

scientific article published on October 2010

Aquaporin-4 water channels in enteric neurons

scientific article published on February 2008

Array analysis of gene expression in connexin-43 null astrocytes.

scientific article

Astrocytic 'power-grid': Delivery upon neuronal demand.

scientific article published on January 2009

Author Correction: Emerging importance of satellite glia in nervous system function and dysfunction

correction of a scholarly article

Automated cell-based assay for screening of aquaporin inhibitors.

scientific article published in October 2009

Bidirectional calcium signaling between satellite glial cells and neurons in cultured mouse trigeminal ganglia

scientific article

Blockade of gap junctions in vivo provides neuroprotection after perinatal global ischemia

scientific article published on 22 September 2005

Bone marrow cell therapy ameliorates and reverses chagasic cardiomyopathy in a mouse model

scientific article

C-erbB2/neu transfection induces gap junctional communication incompetence in glial cells.

scientific article published on July 1996

Calmodulin dependent protein kinase increases conductance at gap junctions formed by the neuronal gap junction protein connexin36.

scientific article

Cellular Environment Remodels the Genomic Fabrics of Functional Pathways in Astrocytes

scientific article published on 07 May 2020

Cell–Cell Communication: An Overview Emphasizing Gap Junctions

scholarly article published 2004

Chagas heart disease: report on recent developments

scientific article published on March 2012

Characterization of connexin 30.3 and 43 in thymocytes

scientific article

Characterization of gap junctions between cultured leptomeningeal cells ⬇️

scientific article published on December 24, 1991

Characterization of hTERT-immortalized osteoblast cell lines generated from wild-type and connexin43-null mouse calvaria

scientific article

Chemical induction of cardiac differentiation in p19 embryonal carcinoma stem cells

scientific article

Cognitive dysfunction in mice infected with Plasmodium berghei strain ANKA.

scientific article published on June 2008

Comparison of pH and calcium dependence of gap junctional conductance

scientific article published on January 1, 1981

Complex channel activity recorded from rat liver gap junctional membranes incorporated into lipid bilayers

scientific article published on January 1, 1991

Concentrative transport of antifolates mediated by the proton-coupled folate transporter (PCFT, SLC46A1); augmentation by a HEPES buffer

scientific article published on 11 January 2018

Connexin 43 Mediates White Adipose Tissue Beiging by Facilitating the Propagation of Sympathetic Neuronal Signals.

scientific article

Connexin Expression (Gap Junctions and Hemichannels) in Astrocytes

Connexin Type and Fluorescent Protein Fusion Tag Determine Structural Stability of Gap Junction Plaques

scientific article

Connexin and pannexin mediated cell-cell communication.

scientific article published on August 2007

Connexin family members target to lipid raft domains and interact with caveolin-1

scientific article (publication date: 7 May 2002)

Connexin-dependent transcellular transcriptomic networks in mouse brain

scientific article published on 3 April 2007

Connexin32 gap junction channels in stably transfected cells. Equilibrium and kinetic properties ⬇️

scientific article published on November 1, 1991

Connexin32 gap junction channels in stably transfected cells: unitary conductance ⬇️

scientific article published on November 1, 1991

Connexin43 and pannexin1 channels in osteoblasts: who is the "hemichannel"?

scientific article

Connexin43 and the brain transcriptome of newborn mice

scientific article published on 24 October 2006

Connexin43, the major gap junction protein of astrocytes, is down-regulated in inflamed white matter in an animal model of multiple sclerosis

scientific article

Connexins modulate autophagosome biogenesis

scientific article

Connexins, pannexins, innexins: novel roles of "hemi-channels"

scientific article published on 14 October 2008

Control and variability of gene expression in mouse brain and in a neuroblastoma cell line.

scientific article published on January 2002

Control of intercellular communication by voltage dependence of gap junctional conductance.

scientific article published in January 1983

Correction to: Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse posttraumatic osteoarthritis model

scholarly article published in Arthritis Research and Therapy

Correction: optimized labeling of bone marrow mesenchymal cells with superparamagnetic iron oxide nanoparticles and in vivo visualization by magnetic resonance imaging.

scientific article published on 6 April 2011

Coupled Activation of Primary Sensory Neurons Contributes to Chronic Pain.

scientific article

Cysteine residues in the cytoplasmic carboxy terminus of connexins dictate gap junction plaque stability

scientific article published on 23 August 2017

Determination of synaptic phenotype: insulin and cAMP independently initiate development of electrotonic coupling between cultured sympathetic neurons ⬇️

scientific article published on October 1, 1984

Developments in the management of Chagas cardiomyopathy

scientific article published on 23 October 2015

Disruption of calcium homeostasis in cardiomyocytes underlies cardiac structural and functional changes in severe sepsis.

scientific article

Echocardiography-based hemodynamic management in the cardiac surgical intensive care unit

scientific article published on 13 December 2013

Effect of mesenchymal stem cells and mouse embryonic fibroblasts on the development of preimplantation mouse embryos.

scientific article published on 07 January 2016

Effect of microgravity on gene expression in mouse brain.

scientific article published on 14 August 2008

Effect of reduced acclimation temperature on responses of frog cold receptors ⬇️

scientific article published on February 1, 1975

Effects of ageing and streptozotocin-induced diabetes on connexin43 and P2 purinoceptor expression in the rat corpora cavernosa and urinary bladder

scientific article

Effects of cholinergic agonists and antagonists on frog cutaneous cold receptors

scientific article published on January 1, 1975

Electrical synapses getting translational

scientific article

Electrotonic Coupling: Effective Sign Reversal by Inhibitory Neurons ⬇️

scientific article published on December 3, 1976

Electrotonic synapses between Aplysia neurons in situ and in culture: aspects of regulation and measurements of permeability.

scientific article

Emerging importance of satellite glia in nervous system function and dysfunction

scientific article published on 22 July 2020

Endothelin-1 Mediates Brain Microvascular Dysfunction Leading to Long-Term Cognitive Impairment in a Model of Experimental Cerebral Malaria

scientific article

Extracellular K⁺ and astrocyte signaling via connexin and pannexin channels

scientific article published on 06 April 2012

Flow cytometry analysis of gap junction-mediated cell-cell communication: advantages and pitfalls

scientific article

Fluid Flow-induced Soluble Vascular Endothelial Growth Factor Isoforms Regulate Actin Adaptation in Osteoblasts ⬇️

scientific article published on August 3, 2010

Fluid shear stress remodels expression and function of junctional proteins in cultured bone cells

Fluid shear stress upregulates vascular endothelial growth factor gene expression in osteoblasts

scientific article

Focal Inflammation Causes Carbenoxolone-Sensitive Tactile Hypersensitivity in Mice

scientific article

Following tracks of hemichannels

scientific article published on July 2003

Functional and transcriptomic recovery of infarcted mouse myocardium treated with bone marrow mononuclear cells.

scientific article published on March 2012

Functional genomic fabrics are remodeled in a mouse model of Chagasic cardiomyopathy and restored following cell therapy.

scientific article

Gap Junctions

Gap junction and purinergic P2 receptor proteins as a functional unit: insights from transcriptomics

scientific article published in June 2007

Gap junction channels: distinct voltage-sensitive and -insensitive conductance states ⬇️

scientific article published on July 1, 1994

Gap junction channels: yes, there are substates, but what does that mean? ⬇️

scientific article published on August 1, 1994

Gap junction distribution is altered between cardiac myocytes infected with Trypanosoma cruzi

scientific article published on 01 April 1992

Gap junction mediated signaling between satellite glia and neurons in trigeminal ganglia

scientific article published on 04 February 2019

Gap junction-mediated intercellular diffusion of Ca2+ in cultured human corporal smooth muscle cells

scientific article published on 01 August 1992

Gap junctional communication in health and disease

scientific article published on 21 November 2014

Gap junctions and Bystander Effects: Good Samaritans and executioners.

scientific article published on 11 December 2012

Gap junctions and chagas disease

scientific article published on January 2011

Gap junctions between cultured astrocytes: immunocytochemical, molecular, and electrophysiological analysis

scientific article published on 01 May 1991

Gap junctions in the brain: where, what type, how many and why? ⬇️

scientific article published on May 1, 1993

Gap junctions mediate bystander cell death in developing retina

scientific article

Gap junctions, pannexins and pain.

scientific article

Gating and Single Channel Properties of Gap Junction Channels in Hepatopancreatic Cells of Procambarus clarkii

scientific article published in October 1992

Gating of gap junction channels ⬇️

scientific article published on January 1, 1984

Gene expression alterations in a mouse model of cerebral malaria

article

Gene expression alterations in connexin null mice extend beyond the gap junction.

scientific article

Genes controlling multiple functional pathways are transcriptionally regulated in connexin43 null mouse heart

scientific article published on 7 December 2004

Glial pannexin1 contributes to tactile hypersensitivity in a mouse model of orofacial pain.

scientific article published on 02 December 2016

Graded, unitary and eye movement potentials in lateral geniculate nucleus following reticular stimulation

scientific article published on March 1, 1975

Green tea polyphenol treatment is chondroprotective, anti-inflammatory and palliative in a mouse post-traumatic osteoarthritis model.

scientific article

Heterogeneity in gap junction expression in astrocytes cultured from different brain regions ⬇️

scientific article published on January 1, 1992

High glucose attenuates shear-induced changes in endothelial hydraulic conductivity by degrading the glycocalyx

scientific article

Hits and misses from gene expression ratio measurements in cDNA microarray studies

scientific article

Human and mouse microglia express connexin36, and functional gap junctions are formed between rodent microglia and neurons

scientific article

Human liver cell trafficking mutants: characterization and whole exome sequencing

scientific article

Hypertension in connexin40-null mice: a renin disorder

scientific article published on 01 October 2007

IGF-I regulates tight-junction protein claudin-1 during differentiation of osteoblast-like MC3T3-E1 cells via a MAP-kinase pathway

scientific article published on 15 October 2008

Identification of a functional prostanoid-like receptor in the protozoan parasite, Trypanosoma cruzi

scientific article published on 13 February 2013

Illuminating gap junctions

scientific article published on 01 January 2005

Improved procedures to mine data obtained from spotted cDNA arrays.

scientific article

In vitro motility of liver connexin vesicles along microtubules utilizes kinesin motors

scientific article

Inhibitors of the 5-lipoxygenase pathway activate pannexin1 channels in macrophages via the thromboxane receptor

scientific article

Initial clinical experience with a miniaturized transesophageal echocardiography probe in a cardiac intensive care unit.

scientific article

Introduction to Connexins and Pannexins in the Healthy and Diseased Nervous System with Thanks to Felikas Bukauskas

scientific article published on 01 March 2019

Involvement of gap junctions in tumorigenesis: transfection of tumor cells with connexin 32 cDNA retards growth in vivo ⬇️

scientific article published on December 1, 1991

Labeling stem cells with superparamagnetic iron oxide nanoparticles: analysis of the labeling efficacy by microscopy and magnetic resonance imaging

scientific article published on January 2012

Lack of "hemichannel" activity in insulin-producing cells

scientific article published on May 2008

Mechanisms of glutamate release from astrocytes: gap junction "hemichannels", purinergic receptors and exocytotic release.

scientific article published on July 2004

Mefloquine blockade of Pannexin1 currents: resolution of a conflict.

scientific article

Mesenchymal bone marrow cell therapy in a mouse model of chagas disease. Where do the cells go?

scientific article

Metabolic dependence of frog cold receptor sensitivity ⬇️

scientific article published on June 7, 1974

Microarray analysis of changes in gene expression in a murine model of chronic chagasic cardiomyopathy.

scientific article published on 9 August 2003

Microarray technology in the investigation of diseases of myocardium with special reference to infection

scientific article

Modulatory effects of cAMP and PKC activation on gap junctional intercellular communication among thymic epithelial cells

scientific article

Molecular cloning and functional expression of zfCx52.6: a novel connexin with hemichannel-forming properties expressed in horizontal cells of the zebrafish retina

scientific article published on 28 October 2003

Molecular imaging, biodistribution and efficacy of mesenchymal bone marrow cell therapy in a mouse model of Chagas disease

scientific article

Neuronal growth factors: lessons from nonneural tissues

scientific article published on 01 January 1988

New possible roles for aquaporin-4 in astrocytes: cell cytoskeleton and functional relationship with connexin43.

scientific article published on 15 August 2005

Optimized labeling of bone marrow mesenchymal cells with superparamagnetic iron oxide nanoparticles and in vivo visualization by magnetic resonance imaging

scientific article

Organizational principles of the connexin-related brain transcriptome

scientific article published on 27 July 2007

P2X7R-Panx1 Complex Impairs Bone Mechanosignaling under High Glucose Levels Associated with Type-1 Diabetes

scientific article

Pannexin 1 channels play essential roles in urothelial mechanotransduction and intercellular signaling

scientific article

Pannexin 1: the molecular substrate of astrocyte "hemichannels".

scientific article

Pannexin channels are not gap junction hemichannels

scientific article published on May 2011

Pannexin-1 and P2X7-Receptor Are Required for Apoptotic Osteocytes in Fatigued Bone to Trigger RANKL Production in Neighboring Bystander Osteocytes.

scientific article

Pannexin1 is part of the pore forming unit of the P2X(7) receptor death complex

scientific article

Pathology of mechanical and gap junctional co-coupling at the intercalated disc: Is sepsis a junctionopathy?

scientific article published on 01 September 2007

Permeability of gap junctions between embryonic cells of Fundulus: a reevaluation

scientific article published on 01 July 1978

Persistent cognitive and motor deficits after successful antimalarial treatment in murine cerebral malaria ⬇️

scientific article published on August 26, 2010

Perspectives on Trypanosoma cruzi-induced heart disease (Chagas disease).

scientific article published on May 2009

Phosphorylation shifts unitary conductance and modifies voltage dependent kinetics of human connexin43 gap junction channels ⬇️

scientific article published on April 1, 1992

Point mutation in the mouse P2X7 receptor affects intercellular calcium waves in astrocytes

scientific article

Potent block of Cx36 and Cx50 gap junction channels by mefloquine

scholarly article

Potential role for a specialized β3 integrin-based structure on osteocyte processes in bone mechanosensation.

scientific article published on 31 October 2017

Preprocedural fasting for coronary interventions: is it time to change practice?

scientific article published on 17 April 2014

Promises and pitfalls of a Pannexin1 transgenic mouse line

scientific article published on 9 May 2013

Properties of channels from rat liver gap junction membrane fractions incorporated into planar lipid bilayers

scientific article published on 01 January 1992

Prospects for rational development of pharmacological gap junction channel blockers

scientific article

Purification of cell populations from human fetal brain using flow cytometric techniques ⬇️

scientific article published on April 18, 1995

Regulation of connexin43-protein binding in astrocytes in response to chemical ischemia/hypoxia

scientific article published on 22 December 2004

Responsive Astrocytic Endfeet: The Role of AQP4 in BBB Development and Functioning

scientific article published on 31 May 2007

Reversion of gene expression alterations in hearts of mice with chronic chagasic cardiomyopathy after transplantation of bone marrow cells

scientific article

Sensitivity of the brain transcriptome to connexin ablation.

scientific article

Sex-dependent gene regulatory networks of the heart rhythm.

scientific article

Shear-induced endothelial NOS activation and remodeling via heparan sulfate, glypican-1, and syndecan-1.

scientific article published on 30 January 2014

Similar transcriptomic alterations in Cx43 knockdown and knockout astrocytes

scientific article published on May 2008

Stationary and non-stationary occurrences of miniature end plate potentials are well described as stationary and non-stationary Poisson processes in the mollusc Navanax inermis ⬇️

scientific article published on June 28, 1988

Strain-induced mechanotransduction through primary cilia, extracellular ATP, purinergic calcium signaling, and ERK1/2 transactivates CITED2 and downregulates MMP-1 and MMP-13 gene expression in chondrocytes.

scientific article published on 11 December 2015

Structural and Functional Consequences of Connexin 36 (Cx36) Interaction with Calmodulin.

scientific article published on 18 November 2016

Structural order in Pannexin 1 cytoplasmic domains

scientific article

Synaptic connections of buccal mechanosensory neurons in the opisthobranch mollusc,Navanax inermis ⬇️

scientific article published on January 27, 1980

The Drosophila period Gene and Dye Coupling in Larval Salivary Glands: A Re-evaluation

scientific article published in October 1992

The Einstein-Brazil Fogarty: A decade of synergy

scientific article

The bystander effect exerted by tumor cells expressing the herpes simplex virus thymidine kinase (HSVtk) gene is dependent on connexin expression and cell communication via gap junctions ⬇️

scientific article published on June 1, 1997

The carboxyl-terminal domain of connexin43 is a negative modulator of neuronal differentiation

scientific article

The connexin43-dependent transcriptome during brain development: importance of genetic background.

scientific article

The future provision of specialist oral surgery and orthodontic services

The gap junction protein connexin32 interacts with the Src homology 3/hook domain of discs large homolog 1.

scientific article

The neuronal connexin36 interacts with and is phosphorylated by CaMKII in a way similar to CaMKII interaction with glutamate receptors

scholarly article

The role of connexins in controlling cell growth and gene expression

scientific article published on 16 March 2007

The role of gap junctions and ion channels in the modulation of electrical and chemical signals in human corpus cavernosum smooth muscle

scientific article published on June 1, 1993

The speed of swelling kinetics modulates cell volume regulation and calcium signaling in astrocytes: A different point of view on the role of aquaporins

scientific article published on 28 September 2015

Transcriptional and posttranscriptional control of connexin mRNAs in periportal and pericentral rat hepatocytes

scientific article published on 01 October 1992

Transcriptome profiling of hippocampal CA1 after early-life seizure-induced preconditioning may elucidate new genetic therapies for epilepsy.

scientific article

Transcriptomic alterations in Trypanosoma cruzi-infected cardiac myocytes.

scientific article

Transcriptomic changes in developing kidney exposed to chronic hypoxia.

scientific article published on 18 August 2006

Transcriptomic characterization of four classes of cell-cell/cell-matrix genes in brains and hearts of wild type and connexin43 null mice.

scientific article published in January 2002

Transcriptomic signatures of alterations in a myoblast cell line infected with four distinct strains of Trypanosoma cruzi

scientific article

Transforming growth factor-beta 1 and forskolin modulate gap junctional communication and cellular phenotype of cultured Schwann cells

scientific article published on 01 January 1995

Trypanosoma cruzi Promotes Transcriptomic Remodeling of the JAK/STAT Signaling and Cell Cycle Pathways in Myoblasts

scientific article published on 17 June 2020

Trypanosoma cruzi induces changes in cardiac connexin43 expression.

scientific article published on 2 October 2007

Trypanosoma cruzi infection results in the reduced expression of caveolin-3 in the heart ⬇️

scientific article published on 15 April 2010

Tubulin-Dependent Transport of Connexin-36 Potentiates the Size and Strength of Electrical Synapses

scientific article published on 25 September 2019

Two non-vesicular ATP release pathways in the mouse erythrocyte membrane.

scientific article published on October 2011

Use of organotypic cultures of Corti's organ to study the protective effects of antioxidant molecules on cisplatin-induced damage of auditory hair cells

scientific article published on 01 September 1997

Voltage Dependence of Junctional Conductance in Early Amphibian Embryos ⬇️

scientific article published on April 27, 1979

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