Search filters

List of works by Roberto Pisano

A model-based approach for the rational design of the freeze-thawing of a protein-based formulation

scientific article published on 05 May 2020

A new method based on the regression of step response data for monitoring a freeze-drying cycle.

scientific article

Advanced approach to build the design space for the primary drying of a pharmaceutical freeze-drying process.

scientific article published on 23 June 2011

Clarifying the role of cryo- and lyo-protectants in the biopreservation of proteins

scientific article published on 12 March 2018

Effect of Surfactants on Surface-Induced Denaturation of Proteins: Evidence of an Orientation-Dependent Mechanism

scientific article published on 10 September 2018

Freeze-drying of enzymes in case of water-binding and non-water-binding substrates

scientific article published on March 14, 2013

General and adaptive synthesis protocol for high-quality organosilane self-assembled monolayers as tunable surface chemistry platforms for biochemical applications

scientific article published on 22 July 2020

Heightened Cold-Denaturation of Proteins at the Ice-Water Interface

scientific article published on 16 March 2020

Impact of controlled vacuum induced surface freezing on the freeze drying of human plasma

scientific article published on 31 March 2020

Impact of vacuum-induced surface freezing on inter- and intra-vial heterogeneity.

scientific article published on 5 April 2016

In-line optimization and control of an industrial freeze-drying process for pharmaceuticals.

scientific article published in November 2010

Looking inside the 'black box': Freezing engineering to ensure the quality of freeze-dried biopharmaceuticals

scientific article published on 19 May 2018

Monitoring of the secondary drying in freeze-drying of pharmaceuticals.

scientific article

Quality by Design: Scale-Up of Freeze-Drying Cycles in Pharmaceutical Industry

scientific article published on July 25, 2013

Quality by design: optimization of a freeze-drying cycle via design space in case of heterogeneous drying behavior and influence of the freezing protocol.

scientific article published on 19 October 2012

Stability of Proteins in Carbohydrates and Other Additives During Freezing: The Human Growth Hormone as a Case Study.

scientific article

Supporting data and methods for the multi-scale modelling of freeze-drying of microparticles in packed-beds

scientific article published on 28 December 2018

Surface-induced crystallization of pharmaceuticals and biopharmaceuticals: A review

scientific article published on 31 May 2018

Surfactants as Stabilizers for Biopharmaceuticals: An Insight into the Molecular Mechanisms for Inhibition of Protein Aggregation

scientific article published on 10 April 2018

Synthesis of high payload nanohydrogels for the ecapsulation of hydrophilic molecules via inverse miniemulsion polymerization: caffeine as a case study

scientific article published on 08 October 2019

The Preservation of Lyophilized Human Growth Hormone Activity: how Do Buffers and Sugars Interact?

scientific article published on 26 April 2018

Vacuum Induced Surface Freezing as an effective method for improved inter- and intra-vial product homogeneity.

scientific article

Water entrapment and structure ordering as protection mechanisms for protein structural preservation.

scientific article published in February 2018