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List of works by Nicholas W Morrell

A 3D tri-culture system reveals that activin receptor-like kinase 5 and connective tissue growth factor drive human glomerulosclerosis.

scientific article published on 16 August 2017

A Potential Role for Exosomal Translationally Controlled Tumor Protein Export in Vascular Remodeling in Pulmonary Arterial Hypertension

A Role for miR-145 in Pulmonary Arterial Hypertension

scientific article published on 19 June 2012

A Sex-Specific MicroRNA-96/5-Hydroxytryptamine 1B Axis Influences Development of Pulmonary Hypertension

scientific journal article

A novel RASA1 mutation causing capillary malformation-arteriovenous malformation (CM-AVM) presenting during pregnancy

scientific article

A novel piperidine identified by stem cell based screening attenuates pulmonary arterial hypertension via regulating BMP2 and PTGS2 levels

scientific article published on 15 February 2018

A one-year-old baby… into the Year of the Dragon

scientific article published in January 2012

A practical and efficient cellular substrate for the generation of induced pluripotent stem cells from adults: blood-derived endothelial progenitor cells

scientific article

A pro-con debate: current controversies in PAH pathogenesis at the American Thoracic Society International Conference in 2017

scientific article published on 07 June 2018

A sex-specific reconstitution bias in the competitive CD45.1/CD45.2 congenic bone marrow transplant model

scientific article

A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension

scientific article published on 15 November 2019

ACE genotype and risk of high altitude pulmonary hypertension in Kyrghyz highlanders.

scientific article published in March 1999

Activin-like kinase 5 (ALK5) mediates abnormal proliferation of vascular smooth muscle cells from patients with familial pulmonary arterial hypertension and is involved in the progression of experimental pulmonary arterial hypertension induced by mo

scientific article published on 30 December 2008

Adrenomedullin expression and growth inhibitory effects in distinct pulmonary artery smooth muscle cell subpopulations.

scientific article

Altered bone morphogenetic protein and transforming growth factor-beta signaling in rat models of pulmonary hypertension: potential for activin receptor-like kinase-5 inhibition in prevention and progression of disease

scientific article published on 19 January 2009

Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to transforming growth factor-beta(1) and bone morphogenetic proteins

scientific article

An antiproliferative BMP-2/PPARgamma/apoE axis in human and murine SMCs and its role in pulmonary hypertension

scientific article published in May 2008

An official American Thoracic Society Statement: pulmonary hypertension phenotypes

scientific article

Angiotensin II activates MAPK and stimulates growth of human pulmonary artery smooth muscle via AT1 receptors

scientific article published on 01 September 1999

Angiotensin II stimulates proliferation of human pulmonary artery smooth muscle cells via the AT1 receptor.

scientific article

Angiotensin converting enzyme expression is increased in small pulmonary arteries of rats with hypoxia-induced pulmonary hypertension.

scientific article published on October 1995

Anticipated classes of new medications and molecular targets for pulmonary arterial hypertension

scientific article published on January 2013

Assessment of a pulmonary origin for blood outgrowth endothelial cells by examination of identical twins harboring a BMPR2 mutation

scientific article published in July 2013

BMP type II receptor deficiency confers resistance to growth inhibition by TGF-β in pulmonary artery smooth muscle cells: role of proinflammatory cytokines

scientific article published on 6 January 2012

BMP-9 induced endothelial cell tubule formation and inhibition of migration involves Smad1 driven endothelin-1 production

scientific article

BMP4 induces HO-1 via a Smad-independent, p38MAPK-dependent pathway in pulmonary artery myocytes

scientific article

BMP4 inhibits proliferation and promotes myocyte differentiation of lung fibroblasts via Smad1 and JNK pathways

scientific article

BMP9 mutations cause a vascular-anomaly syndrome with phenotypic overlap with hereditary hemorrhagic telangiectasia

scientific article

BMPR2 gene rearrangements account for a significant proportion of mutations in familial and idiopathic pulmonary arterial hypertension

article

BMPR2 mutations and survival in pulmonary arterial hypertension: an individual participant data meta-analysis

scientific article

Better off blue: BMPR-2 mutation, arteriovenous malformation, and pulmonary arterial hypertension

scientific article published in June 2014

Bone Morphogenetic Protein 9 Enhances Lipopolysaccharide-Induced Leukocyte Recruitment to the Vascular Endothelium

scientific article published on 19 September 2016

Bone Morphogenetic Protein 9 Protects against Neonatal Hyperoxia-Induced Impairment of Alveolarization and Pulmonary Inflammation

scientific article published on 13 July 2017

Bone Morphogenetic Protein 9 is a Mechanistic Biomarker of Portopulmonary Hypertension

scientific article published on 01 April 2019

Bone morphogenetic protein (BMP) and activin type II receptors balance BMP9 signals mediated by activin receptor-like kinase-1 in human pulmonary artery endothelial cells

scientific article

Bone morphogenetic protein 9 (BMP9) and BMP10 enhance tumor necrosis factor-α-induced monocyte recruitment to the vascular endothelium mainly via activin receptor-like kinase 2.

scientific article published on 23 June 2017

Bone morphogenetic protein receptor type II deficiency and increased inflammatory cytokine production. A gateway to pulmonary arterial hypertension

scientific article

Bone morphogenetic protein signaling is required for RAD51-mediated maintenance of genome integrity in vascular endothelial cells

Bone morphogenetic protein type 2 receptor gene therapy attenuates hypoxic pulmonary hypertension

scientific article published on 2 February 2007

Bosentan in inoperable chronic thromboembolic pulmonary hypertension.

scientific article published in August 2005

Buccal nitroglycerin tablets in heart failure

scientific article

Caveolae protect endothelial cells from membrane rupture during increased cardiac output

scientific article

Cellular and molecular basis of pulmonary arterial hypertension

scientific article published on June 2009

Cellular and molecular pathobiology of pulmonary arterial hypertension ⬇️

scientific article published on June 2004

Changes in Regional Pulmonary Blood Flow during Lobar Bronchial Occlusion in Man

scientific article published on 01 May 1994

Characterization of high-altitude pulmonary hypertension in the Kyrgyz: association with angiotensin-converting enzyme genotype

scientific article

Characterization of the BMPR2 5'-untranslated region and a novel mutation in pulmonary hypertension

scientific article

Chloroquine prevents progression of experimental pulmonary hypertension via inhibition of autophagy and lysosomal bone morphogenetic protein type II receptor degradation

scientific article published on 27 February 2013

Circulating angiogenic modulatory factors predict survival and functional class in pulmonary arterial hypertension

scientific article published on April 2013

Clinical and molecular genetic features of pulmonary hypertension in patients with hereditary hemorrhagic telangiectasia.

scientific article

Collateral Ventilation and Gas Exchange during Airway Occlusion in the Normal Human Lung

scientific article published on 01 March 1993

Collateral ventilation and gas exchange in emphysema.

scientific article

Consequences Of Natural Perturbations In The Human Plasma Proteome

article

Constitutively active ALK2 receptor mutants require type II receptor cooperation

scientific article published on 09 April 2013

Contributions of BMPR2 Mutations and Extrinsic Factors to Cellular Phenotypes of Pulmonary Arterial Hypertension Revealed by iPSC Modeling.

scientific article published on 16 March 2018

Correction for Bagarova et al., "Constitutively Active ALK2 Receptor Mutants Require Type II Receptor Cooperation"

scientific article published on 12 September 2017

Correction of nonsense BMPR2 and SMAD9 mutations by ataluren in pulmonary arterial hypertension.

scientific article published on September 2013

Correction: BMP-9 Induced Endothelial Cell Tubule Formation and Inhibition of Migration Involves Smad1 Driven Endothelin-1 Production

scientific article published in PLoS ONE

Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP10

scientific article published on 03 May 2022

Current differences in referral patterns for pulmonary endarterectomy in the UK.

scientific article published in September 2008

Demographic features, BMPR2 status and outcomes in distal chronic thromboembolic pulmonary hypertension

scientific article

Deprivation and prognosis in patients with Pulmonary Arterial Hypertension: missing the effect of deprivation on a rare disease?

scientific article published on 16 April 2020

Developmental regulation of angiotensin converting enzyme and angiotensin type 1 receptor in the rat pulmonary circulation.

scientific article published in June 1996

Differential IL-1 signaling induced by BMPR2 deficiency drives pulmonary vascular remodeling

scientific article published in January 2017

Differential adrenomedullin release and endothelin receptor expression in distinct subpopulations of human airway smooth-muscle cells.

scientific article

Differential effects of TGF-beta1 and BMP-4 on the hypoxic induction of cyclooxygenase-2 in human pulmonary artery smooth muscle cells

scientific article published on 25 June 2004

Disrupted Endothelial Cell Layer and Exposed Extracellular Matrix Proteins Promote Capture of Late Outgrowth Endothelial Progenitor Cells

scientific article published on 16 June 2016

Distinct responses to hypoxia in subpopulations of distal pulmonary artery cells contribute to pulmonary vascular remodeling in emphysema.

scientific article

Does BMPR2 Mutation Disrupt Pulmonary Vasculogenesis?

scientific article published on 01 December 2005

Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline

scientific article

Dysfunctional Smad Signaling Contributes to Abnormal Smooth Muscle Cell Proliferation in Familial Pulmonary Arterial Hypertension

scientific article published on 21 April 2005

ET(A) and ET(B) receptors modulate the proliferation of human pulmonary artery smooth muscle cells

scientific article published in February 2002

Elabela/Toddler Is an Endogenous Agonist of the Apelin APJ Receptor in the Adult Cardiovascular System, and Exogenous Administration of the Peptide Compensates for the Downregulation of Its Expression in Pulmonary Arterial Hypertension

scientific article published on 30 January 2017

Endothelial apoptosis in pulmonary hypertension is controlled by a microRNA/programmed cell death 4/caspase-3 axis

scientific journal article

Eotaxin-1/CC chemokine ligand 11: a novel eosinophil survival factor secreted by human pulmonary artery endothelial cells

scientific article published in July 2007

Evidence for the involvement of type I interferon in pulmonary arterial hypertension

scientific article published on 13 December 2013

Evidence of dysfunction of endothelial progenitors in pulmonary arterial hypertension

scientific article published on 23 July 2009

Expression of pulmonary vascular angiotensin-converting enzyme in primary and secondary plexiform pulmonary hypertension

scientific article published on 01 November 2000

Failure of bone morphogenetic protein receptor trafficking in pulmonary arterial hypertension: potential for rescue

scientific article published on 21 July 2008

Familial pulmonary arterial hypertension by KDR heterozygous loss of function

scientific article published on 03 April 2020

Familial spontaneous pneumothorax and lung cysts due to a Folliculin exon 10 mutation.

scientific article published in June 2009

Fibrinogen Aalpha Thr312Ala polymorphism is associated with chronic thromboembolic pulmonary hypertension

scientific article published on 5 December 2007

Flexibility and diversity in consultant careers

Functional analysis of bone morphogenetic protein type II receptor mutations underlying primary pulmonary hypertension

scientific article

Functional characterization of bone morphogenetic protein binding sites and Smad1/5 activation in human vascular cells

scientific article published on 7 November 2007

Functional interaction between BMPR-II and Tctex-1, a light chain of Dynein, is isoform-specific and disrupted by mutations underlying primary pulmonary hypertension

scientific article

Future breakthroughs in the genetics of pulmonary arterial hypertension

scientific article

Generation and Culture of Blood Outgrowth Endothelial Cells from Human Peripheral Blood

scientific article published on 23 December 2015

Genetic and molecular mechanisms of pulmonary hypertension.

scientific article

Genetic association of the serotonin transporter in pulmonary arterial hypertension.

scientific article published on 6 January 2006

Genetic determinants of risk and survival in pulmonary arterial hypertension

article

Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis

scientific article published on 05 December 2018

Genetics and genomics of pulmonary arterial hypertension

article

Genetics and the molecular pathogenesis of pulmonary arterial hypertension

scientific article published on December 2013

Genetics of pulmonary arterial hypertension: do the molecular findings have translational value? ⬇️

scientific article published on March 25, 2010

Genomic atlas of the human plasma proteome

scientific article published in Nature

Germline selection shapes human mitochondrial DNA diversity

scientific article published on 23 May 2019

Global analysis of the haematopoietic and endothelial transcriptome during zebrafish development

scientific article published on 13 October 2012

Gremlin plays a key role in the pathogenesis of pulmonary hypertension

scientific article

Growth/differentiation factor 15 causes TGFβ-activated kinase 1-dependent muscle atrophy in pulmonary arterial hypertension

scientific article published on 15 December 2018

HIF2α-arginase axis is essential for the development of pulmonary hypertension.

scientific article published on 18 July 2016

Hematopoietic stem cell transplantation alters susceptibility to pulmonary hypertension in Bmpr2-deficient mice

Hepatic Shunting of Eggs and Pulmonary Vascular Remodeling in Bmpr2(+/-) Mice with Schistosomiasis.

scientific article published on 26 August 2015

Hypoxic induction of cox-2 regulates proliferation of human pulmonary artery smooth muscle cells

scientific article published in December 2002

Id proteins are critical downstream effectors of BMP signaling in human pulmonary arterial smooth muscle cells

scientific article published on 14 June 2013

Id proteins in the vasculature: from molecular biology to cardiopulmonary medicine

scientific article published on October 2014

Identification of miR-124 as a Major Regulator of Enhanced Endothelial Cell Glycolysis in Pulmonary Arterial Hypertension via PTBP1 and PKM2.

scientific article published on 26 September 2017

Identification of novel rare sequence variation underlying heritable pulmonary arterial hypertension

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension

scientific article published on 12 April 2018

Imatinib mesylate as add-on therapy for pulmonary arterial hypertension: results of the randomized IMPRES study.

scientific article

Immunolocalisation of BMPR-II and TGF-ß type I and II receptors in primary plexogenic pulmonary hypertension

scientific article published on 01 February 2001

Impaired Natural Killer Cell Phenotype and Function in Idiopathic and Heritable Pulmonary Arterial Hypertension

article

In vivo assessment of lung inflammatory cell activity in patients with COPD and asthma

scientific article published on April 2003

Increased Antielastase Activity in Idiopathic Pulmonary Arterial Hypertension and Chronic Thromboembolic Pulmonary Hypertension

scientific article published on 01 November 2018

Inflammation, growth factors, and pulmonary vascular remodeling

scientific article published on June 2009

Inhibition of Hyaluronan Synthesis Attenuates Pulmonary Hypertension Associated with Lung Fibrosis.

scientific article

Inhibition of overactive transforming growth factor-β signaling by prostacyclin analogs in pulmonary arterial hypertension

scientific article

Inhibition of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) reverses experimental pulmonary hypertension

scientific article

Investigation of Second Genetic Hits at the BMPR2 Locus as a Modulator of Disease Progression in Familial Pulmonary Arterial Hypertension

scientific article published on 01 February 2005

Large granular lymphocyte leukaemia

scientific article published on 01 June 2005

Late outgrowth endothelial progenitor cells engineered for improved survival and maintenance of function in transplant-related injury

scientific article published on 26 November 2011

Long-term safety and efficacy of imatinib in pulmonary arterial hypertension

scientific article published on 11 June 2015

Long-term use of sildenafil in inoperable chronic thromboembolic pulmonary hypertension

scientific article

Loss of SMAD3 Promotes Vascular Remodeling in Pulmonary Arterial Hypertension via MRTF Disinhibition

scientific article published on 2 November 2017

Loss-of-Function ABCC8 Mutations in Pulmonary Arterial Hypertension

scientific article published on 01 October 2018

Management of pulmonary embolism

scientific article published on 01 March 1993

Mechanism of cicaprost-induced desensitization in rat pulmonary artery smooth muscle cells involves a PKA-mediated inhibition of adenylyl cyclase

scientific article published on 23 April 2004

Mendelian randomisation analysis of red cell distribution width in pulmonary arterial hypertension

scientific article published on 12 February 2020

Metabolic and Proliferative State of Vascular Adventitial Fibroblasts in Pulmonary Hypertension Is Regulated Through a MicroRNA-124/PTBP1 (Polypyrimidine Tract Binding Protein 1)/Pyruvate Kinase Muscle Axis

scientific article published on 26 September 2017

MicroRNA and vascular remodelling in acute vascular injury and pulmonary vascular remodelling

scientific article

MicroRNA-124 controls the proliferative, migratory, and inflammatory phenotype of pulmonary vascular fibroblasts

scientific article

MicroRNA-140-5p and SMURF1 regulate pulmonary arterial hypertension

scientific article

MicroRNA-143 Activation Regulates Smooth Muscle and Endothelial Cell Crosstalk in Pulmonary Arterial Hypertension

scientific journal article

Modulation of endothelin receptors in the failing right ventricle of the heart and vasculature of the lung in human pulmonary arterial hypertension

scientific article

Molecular and cellular basis of pulmonary vascular remodeling in pulmonary hypertension.

scientific article

Molecular and functional analysis identifies ALK-1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia

scientific article

Molecular basis of ALK1-mediated signalling by BMP9/BMP10 and their prodomain-bound forms

scientific article published on 01 April 2020

Molecular genetic framework underlying pulmonary arterial hypertension

scientific article published on 12 August 2019

Molecular mechanisms of pulmonary arterial hypertension: role of mutations in the bone morphogenetic protein type II receptor

scientific article published on December 2008

Mutations in bone morphogenetic protein type II receptor cause dysregulation of Id gene expression in pulmonary artery smooth muscle cells: implications for familial pulmonary arterial hypertension

scientific article published on 24 April 2008

Mutations of the TGF-beta type II receptor BMPR2 in pulmonary arterial hypertension

scientific article

Myeloid angiogenic cells exhibit impaired migration, reduced expression of endothelial markers, and increased apoptosis in idiopathic pulmonary arterial hypertension

scientific article published on 17 December 2018

Myocardin regulates vascular smooth muscle cell inflammatory activation and disease

scientific article

NPR-A–Deficient Mice Show Increased Susceptibility to Hypoxia-Induced Pulmonary Hypertension

scientific article published on 01 February 1999

Neutrophils from patients with heterozygous germline mutations in the von Hippel Lindau protein (pVHL) display delayed apoptosis and enhanced bacterial phagocytosis

scientific article published on 29 June 2006

New insights into the pathogenesis and treatment of primary pulmonary hypertension ⬇️

scientific article published on November 1, 2001

New therapeutic agents for pulmonary vascular disease

scientific article

Nitric oxide, phosphodiesterase inhibition, and adaption to hypoxic conditions

scientific article published on 01 May 2002

Novel insights into maladaptive behaviours in Prader-Willi syndrome: serendipitous findings from an open trial of vagus nerve stimulation.

scientific article published on 27 May 2015

Occlusion pressure analysis role in partitioning of pulmonary vascular resistance in CTEPH

scientific article published on 23 February 2012

Our readership grows by leaps and bounds

scientific article published on December 2016

Phenotypic Characterization of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension

scientific article published on 28 September 2017

Phosphodiesterase type 5 and high altitude pulmonary hypertension.

scientific article published on August 2005

Pilot study of losartan for pulmonary hypertension in chronic obstructive pulmonary disease

scientific article published in August 2005

Plasma Metabolomics Implicates Modified Transfer RNAs and Altered Bioenergetics in the Outcomes of Pulmonary Arterial Hypertension.

scientific article

Plasma metabolomics exhibit response to therapy in chronic thromboembolic pulmonary hypertension

scientific article published on 15 October 2020

Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor

scientific article

Primary pulmonary hypertension: molecular basis and potential for therapy

scientific article published on 9 March 2004

Prostacyclin Analogues Differentially Inhibit Growth of Distal and Proximal Human Pulmonary Artery Smooth Muscle Cells

scientific article published on 01 December 2000

Proteomic analysis implicates translationally controlled tumor protein as a novel mediator of occlusive vascular remodeling in pulmonary arterial hypertension.

scientific article

Pulmonary Arterial Hypertension: A Current Perspective on Established and Emerging Molecular Genetic Defects

scientific article published on 21 September 2015

Pulmonary arterial size and response to sildenafil in chronic thromboembolic pulmonary hypertension

scientific article

Pulmonary hypertension due to BMPR2 mutation: a new paradigm for tissue remodeling?

scientific article published on November 2006

Pulmonary hypertension in patients with COPD: NO treatment?

scientific article published in April 2003

Pulmonary vascular remodeling correlates with lung eggs and cytokines in murine schistosomiasis.

scientific article published on 3 December 2009

Pulmonary veno-occlusive disease: characterising a rare but important disease

scientific article published on 11 January 2017

Readership: The heart of Pulmonary Circulation

scientific article published on January 2013

Receptor for Activated C-Kinase 1, a Novel Interaction Partner of Type II Bone Morphogenetic Protein Receptor, Regulates Smooth Muscle Cell Proliferation in Pulmonary Arterial Hypertension

scientific article published on 21 May 2007

Regional Matching of Ventilation and Perfusion during Lobar Bronchial Occlusion in Man

scientific article published on 01 February 1995

Regulation and Functions of the Paired-Related Homeobox Gene PRX1 in Pulmonary Vascular Development and Disease

scientific article published on 01 December 2005

Regulation and function of miR-214 in pulmonary arterial hypertension

scientific article

Regulation of bone morphogenetic protein 9 (BMP9) by redox-dependent proteolysis.

scientific article

Regulation of bone morphogenetic protein signalling in human pulmonary vascular development

scientific article

Regulation of the ALK1 ligands, BMP9 and BMP10.

scientific article published on August 2016

Relevant issues in the pathology and pathobiology of pulmonary hypertension

scientific article published on December 2013

Reply to “Letter to the Editor: Is Id3 proliferative or antiproliferative?”

scientific article published on 01 August 2018

Response by Hadinnapola et al to Letter Regarding Article, “Phenotypic Characterization of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension”

scientific article published on 01 May 2018

Right ventricular dysfunction in chronic thromboembolic obstruction of the pulmonary artery: a pressure-volume study using the conductance catheter

scientific article published on 19 December 2013

Role of angiotensin-converting enzyme and angiotensin II in development of hypoxic pulmonary hypertension

article

Role of bone morphogenetic protein receptors in the development of pulmonary arterial hypertension

scientific article published on January 2010

Role of the Aryl Hydrocarbon Receptor in Sugen 5416-induced Experimental Pulmonary Hypertension

scientific article published on 28 September 2017

Schistosomiasis causes remodeling of pulmonary vessels in the lung in a heterogeneous localized manner: Detailed study

scientific article published on April 2013

Science is an endless frontier: Encouraging translational research in pulmonary vascular disease

scientific article published on April 2012

Screening for pulmonary arteriovenous malformations.

scientific article

Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension.

scientific article published on 15 June 2015

Serotonin increases susceptibility to pulmonary hypertension in BMPR2-deficient mice

scientific article published on 23 February 2006

Serum osteoprotegerin is increased and predicts survival in idiopathic pulmonary arterial hypertension

scientific article published in January 2012

Sex affects bone morphogenetic protein type II receptor signaling in pulmonary artery smooth muscle cells

scientific article

Sildenafil potentiates bone morphogenetic protein signaling in pulmonary arterial smooth muscle cells and in experimental pulmonary hypertension

scientific article published on 8 November 2012

Sixth Annual Scientific Workshops and Debates of the Pulmonary Vascular Research Institute (PVRI)

Smad-dependent and smad-independent induction of id1 by prostacyclin analogues inhibits proliferation of pulmonary artery smooth muscle cells in vitro and in vivo.

scientific article published on 3 June 2010

Spontaneous pulmonary hypertension in genetic mouse models of natural killer cell deficiency

article published in 2018

Stoichiometric imbalance in the receptor complex contributes to dysfunctional BMPR-II mediated signalling in pulmonary arterial hypertension

scientific article published on 04 March 2008

Supplementation of iron in pulmonary hypertension: Rationale and design of a phase II clinical trial in idiopathic pulmonary arterial hypertension

scientific article published on January 2013

TGF-beta and BMPR-II pharmacology--implications for pulmonary vascular diseases

scientific article published on 25 March 2009

TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling.

scientific article published on 13 January 2017

Targeting BMP signalling in cardiovascular disease and anaemia

scientific article

Targeting translational read-through of premature termination mutations in BMPR2 with PTC124 for pulmonary arterial hypertension

scientific article published on 20 July 2020

Tenascin-C is induced by mutated BMP type II receptors in familial forms of pulmonary arterial hypertension

scientific article published on 16 June 2006

The ADAMTS13-VWF axis is dysregulated in chronic thromboembolic pulmonary hypertension

scientific article published on 28 March 2019

The Prodomain-bound Form of Bone Morphogenetic Protein 10 Is Biologically Active on Endothelial Cells

scientific article

The Pulmonary Vascular Research Institute celebrates its first decade

scientific article published on April 2017

The anatomy of radioisotope lung scanning ⬇️

scientific article published on May 1, 1992

The endothelin system and its role in pulmonary arterial hypertension (PAH).

scientific article published in June 2005

The fibrocyte in pulmonary hypertension: we seek him here, we seek him there

scientific article published on 01 January 2012

The integrated stress response in pulmonary disease

scientific article published on 01 September 2020

The limitations of posterior view ventilation scanning in the diagnosis of pulmonary embolism

scientific article published on 01 November 1993

The lysosomal inhibitor, chloroquine, increases cell surface BMPR-II levels and restores BMP9 signalling in endothelial cells harbouring BMPR-II mutations

scientific article published on 12 May 2013

The promise of recombinant BMP ligands and other approaches targeting BMPR-II in the treatment of pulmonary arterial hypertension

scientific article

The renin-angiotensin system in pulmonary hypertension

scientific article published on May 2013

The rise and rise of Pulmonary Circulation

scientific article published on March 2015

The transforming growth factor-β-bone morphogenetic protein type signalling pathway in pulmonary vascular homeostasis and disease

scientific article published on 03 May 2013

The underestimation of segmental defect size in radionuclide lung scanning.

scientific article published in March 1993

The voice of pulmonary circulation

scientific article published on March 2014

Towards a molecular classification of pulmonary arterial hypertension

scientific article published on 01 October 2016

Traffic exposures, air pollution and outcomes in pulmonary arterial hypertension: A United Kingdom cohort study analysis

scientific article published on 30 May 2019

Transcript analysis reveals a specific HOX signature associated with positional identity of human endothelial cells

scientific article

Transforming growth factor-beta receptor mutations and pulmonary arterial hypertension in childhood

scientific article

Transforming growth factor-β(1) represses bone morphogenetic protein-mediated Smad signaling in pulmonary artery smooth muscle cells via Smad3

scientific article published on December 2013

Treatment with anti-gremlin 1 antibody ameliorates chronic hypoxia/SU5416-induced pulmonary arterial hypertension in mice

scientific article

Tumour necrosis factor-α gene promoter polymorphism in chronic obstructive pulmonary disease

article

Understanding the low penetrance of bone morphogenetic protein receptor 2 gene mutations: another needle in the haystack.

scientific article

Use of Pulsed-Wave Doppler Echocardiography to Measure Changes in MPAP

scientific article published on 01 May 1997

Utility of echocardiography in assessment of pulmonary hypertension secondary to COPD

scientific article published on 01 March 2001

Vascular remodeling and ET-1 expression in rat strains with different responses to chronic hypoxia

article

Waiting in anticipation: the genetics of pulmonary arterial hypertension

scientific article published on November 2012

[Differential diagnosis of pulmonary hypertension]

scientific article published on 01 August 2009

[Relevant issues in the pathology and pathobiology of pulmonary hypertension].

scientific article published in October 2014

cAMP phosphodiesterase inhibitors potentiate effects of prostacyclin analogs in hypoxic pulmonary vascular remodeling

scientific article published on 17 September 2004

miR-322-5p targets IGF-1 and is suppressed in the heart of rats with pulmonary hypertension.

scientific article published on 24 January 2018

α1-A680T variant in GUCY1A3 as a candidate conferring protection from pulmonary hypertension among Kyrgyz highlanders

scientific article published on 4 November 2014

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