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List of works by Alain Kohl

134 A cellular restriction factor blocking replication of an emerging bunyavirus in human cells: clues for cross-species barriers?

scientific article

A bunyamwera virus minireplicon system in mosquito cells

scientific article published on June 2004

A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research

scientific article

Adaptation to host cell environment during experimental evolution of Zika virus

scientific article published in 2022

Advances in dissecting mosquito innate immune responses to arbovirus infection

scientific article published on July 2009

Advancing insect vector biology research: a community survey for future directions, research applications and infrastructure requirements

Advancing vector biology research: a community survey for future directions, research applications and infrastructure requirements

scientific article published on June 2016

Aedes aegypti Piwi4 Is a Noncanonical PIWI Protein Involved in Antiviral Responses ⬇️

scientific article

An Aedes aegypti-Derived Ago2 Knockout Cell Line to Investigate Arbovirus Infections

scientific article published in 2021

Analysis of Zika virus capsid-Aedes aegypti mosquito interactome reveals pro-viral host factors critical for establishing infection

scientific article

Analysis of tick-borne encephalitis virus-induced host responses in human cells of neuronal origin and interferon-mediated protection

scientific article published on 08 August 2017

Antiviral RNA Interference Activity in Cells of the Predatory Mosquito, Toxorhynchites amboinensis.

scientific article published on 6 December 2018

Antiviral RNA interference responses induced by Semliki Forest virus infection of mosquito cells: characterization, origin, and frequency-dependent functions of virus-derived small interfering RNAs

scientific article published on 29 December 2010

Assessing the Potential Interactions between Cellular miRNA and Arboviral Genomic RNA in the Yellow Fever Mosquito, Aedes aegypti

scientific article published on 10 June 2019

BAF45b Is Required for Efficient Zika Virus Infection of HAP1 Cells

scientific article published in 2021

Bunyamwera virus nonstructural protein NSs counteracts interferon regulatory factor 3-mediated induction of early cell death

scientific article

Bunyavirus requirement for endosomal K+ reveals new roles of cellular ion channels during infection ⬇️

scientific article published on 19 January 2018

Characterization of Aedes aegypti innate-immune pathways that limit Chikungunya virus replication

scientific article

Characterization of the Zika virus induced small RNA response in Aedes aegypti cells ⬇️

scientific article published on 17 October 2017

Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen

scientific article

Clinical and Laboratory Diagnosis of SARS-CoV-2, the Virus Causing COVID-19

scientific article published on 04 August 2020

Coinfection of tick cell lines has variable effects on replication of intracellular bacterial and viral pathogens

scientific article published on 29 March 2014

Combined agonist-antagonist genome-wide functional screening identifies broadly active antiviral microRNAs

scientific article

Complementarity, sequence and structural elements within the 3' and 5' non-coding regions of the Bunyamwera orthobunyavirus S segment determine promoter strength

scientific article

Correction: Dengue in Java, Indonesia: Relevance of Mosquito Indices as Risk Predictors.

scientific article published on 26 April 2016

Corrigendum: Analysis of tick-borne encephalitis virus-induced host responses in human cells of neuronal origin and interferon-mediated protection

correction of a scholarly article

Culex quinquefasciatus mosquitoes do not support replication of Zika virus

scientific article published on 27 October 2017

Culex tarsalis is a competent vector species for Cache Valley virus

scholarly article published by Alain Kohl in 2018

Dengue in Java, Indonesia: Relevance of Mosquito Indices as Risk Predictors

scientific article

Detection and identification of putative bacterial endosymbionts and endogenous viruses in tick cell lines

scientific article

Development of a Reverse Genetics System for Toscana Virus (Lineage A)

scientific article published on 07 April 2020

Development of reverse genetics systems and investigation of host response antagonism and reassortment potential for Cache Valley and Kairi viruses, two emerging orthobunyaviruses of the Americas

scientific article published on 29 October 2018

Differential effects of lipid biosynthesis inhibitors on Zika and Semliki Forest viruses

scientific article published on 19 October 2017

Diverse laboratory colonies of Aedes aegypti harbor the same adult midgut bacterial microbiome

scientific article published on 27 March 2018

Effects of a point mutation in the 3' end of the S genome segment of naturally occurring and engineered Bunyamwera viruses

scientific article published on April 2003

Enhanced Zika virus susceptibility of globally invasive Aedes aegypti populations

scientific article published on 01 November 2020

Evaluation of an Engineered Zika Virus-Like Particle Vaccine Candidate in a Mosquito-Mouse Transmission Model

scientific article published in 2023

Exploration of immunological responses underpinning severe fever with thrombocytopenia syndrome virus infection reveals IL-6 as a therapeutic target in an immunocompromised mouse model

Full Genome Sequence and sfRNA Interferon Antagonist Activity of Zika Virus from Recife, Brazil

scientific article (publication date: October 2016)

Gene silencing in tick cell lines using small interfering or long double-stranded RNA.

scientific article published on 7 July 2012

Generation of a reporter yellow fever virus for high throughput antiviral assays

scientific article published on 24 September 2020

Genetic elements regulating packaging of the Bunyamwera orthobunyavirus genome

scientific article published on January 2006

Glucose regulated protein 78 (GRP78) interacts with Zika virus envelope and is required for a productive infection

scientific article published in 2019

Glucose-Regulated Protein 78 Interacts with Zika Virus Envelope Protein and Contributes to a Productive Infection

scientific article published on 09 May 2020

Homage to Richard M. Elliott

scientific article published on 10 August 2016

Homotypic interaction of Bunyamwera virus nucleocapsid protein

scientific article published on October 2005

Host Inflammatory Response to Mosquito Bites Enhances the Severity of Arbovirus Infection ⬇️

scientific article

Identification and RNAi Profile of a Novel Iflavirus Infecting Senegalese Aedes vexans arabiensis Mosquitoes

scientific article published on 14 April 2020

In vitro selection of Remdesivir resistance suggests evolutionary predictability of SARS-CoV-2

scientific article published on 17 September 2021

Infection and transmission of Cache Valley virus by Aedes albopictus and Aedes aegypti mosquitoes

scientific article published on 31 July 2019

Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signalling

scientific article published on 23 March 2018

Inhibition of type I interferon induction and signalling by mosquito-borne flaviviruses

scientific article (publication date: 2017)

Insights into SARS-CoV-2, the Coronavirus Underlying COVID-19: Recent Genomic Data and the Development of Reverse Genetics Systems

scientific article published on 24 June 2020

Insights into molecular evolution recombination of pandemic SARS-CoV-2 using Saudi Arabian sequences

scientific article published on 14 May 2020

Knockdown of piRNA pathway proteins results in enhanced Semliki Forest virus production in mosquito cells

scientific article published on 04 April 2013

M segment-based minigenomes and virus-like particle assays as an approach to assess the potential of tick-borne Phlebovirus genome reassortment ⬇️

scholarly article by Veronica V. Rezelj et al published 19 December 2018 in Journal of Virology

Metaviromics Reveals Unknown Viral Diversity in the Biting Midge Culicoides impunctatus

scientific article published on 17 September 2019

Mitigating the risk of Zika virus contamination of raw materials and cell lines in the manufacture of biologicals

scientific article published on 14 December 2017

Modified recombinant human IgG1-Fc is superior to natural intravenous immunoglobulin at inhibiting immune-mediated demyelination

Modulation of Potassium Channels Inhibits Bunyavirus Infection ⬇️

scientific article published on 16 December 2015

Mosquito-borne arboviruses in Uganda: history, transmission and burden

scientific article published on 24 June 2021

Mosquito-borne arboviruses in Uganda: history, transmission and burden

scientific article published on 05 October 2021

Mutational analysis of Aedes aegypti Dicer 2 provides insights into the biogenesis of antiviral exogenous small interfering RNAs

scientific article published on 06 January 2022

Mutational analysis of Rift Valley fever phlebovirus nucleocapsid protein indicates novel conserved, functional amino acids. ⬇️

scientific article published on 21 December 2017

NSs protein of Rift Valley fever virus blocks interferon production by inhibiting host gene transcription

scientific article

NSs protein of Schmallenberg virus counteracts the antiviral response of the cell by inhibiting its transcriptional machinery

scientific article published on 14 May 2014

Neurons and oligodendrocytes in the mouse brain differ in their ability to replicate Semliki Forest virus

scientific article published on 24 December 2008

Non-structural proteins of arthropod-borne bunyaviruses: roles and functions

scientific article published on 04 October 2013

Noncoding flavivirus RNA displays RNA interference suppressor activity in insect and Mammalian cells

scientific article

Oligodendrocytes are susceptible to Zika virus infection in a mouse model of perinatal exposure: Implications for CNS complications

scientific article

PKR acts early in infection to suppress Semliki Forest virus production and strongly enhances the type I interferon response

scientific article published on 4 March 2009

Phenoloxidase activity acts as a mosquito innate immune response against infection with Semliki Forest virus

scientific article

Population genomics of louping ill virus provide new insights into the evolution of tick-borne flaviviruses

scientific article published on 14 September 2020

Proteomic analysis reveals vector-virus interactions between Zika virus and Aedes aegypti mosquito cells

scientific article published in 2019

RIG-I Plays a Dominant Role in the Induction of Transcriptional Changes in Zika Virus-Infected Cells, which Protect from Virus-Induced Cell Death

scientific article published on 16 June 2020

RNA Interference Restricts Rift Valley Fever Virus in Multiple Insect Systems

scientific article

RNA interference targets arbovirus replication in Culicoides cells

scientific article

Rational Zika vaccine design via the modulation of antigen membrane anchors in chimpanzee adenoviral vectors.

scientific article

Recombination between African and Asian lineages of Zika virus in vitro and its consequences for viral phenotype

scientific article published in 2020

Recombination, and Then What? How Zika Virus Hybrids Improve Their Fitness

scientific article published in 2022

Requirement of the N-terminal region of orthobunyavirus nonstructural protein NSm for virus assembly and morphogenesis

scientific article published on August 2006

Revisiting Key Entry Routes of Human Epidemic Arboviruses into the Mainland Americas through Large-Scale Phylogenomics

scientific article published on 08 October 2018

Role of the cytoplasmic tail domains of Bunyamwera orthobunyavirus glycoproteins Gn and Gc in virus assembly and morphogenesis

scientific article published on 3 July 2007

Schmallenberg virus pathogenesis, tropism and interaction with the innate immune system of the host.

scientific article

Semliki forest virus-induced endoplasmic reticulum stress accelerates apoptotic death of mammalian cells

scientific article published on 28 April 2010

Spindle-E Acts Antivirally Against Alphaviruses in Mosquito Cells

scientific article published on 18 February 2018

Structural and phenotypic analysis of Chikungunya virus RNA replication elements

scientific article published on 01 September 2019

Subgenomic RNA identification in SARS-CoV-2 genomic sequencing data

scientific article published on 15 March 2021

Sugar feeding protects against arboviral infection by enhancing gut immunity in the mosquito vector Aedes aegypti

scientific article published in 2021

The Aedes aegypti Domino Ortholog p400 Regulates Antiviral Exogenous Small Interfering RNA Pathway Activity and ago-2 Expression

scientific article published on 08 April 2020

The Aedes aegypti RNA interference response against Zika virus in the context of co-infection with dengue and chikungunya viruses

scientific article published in 2023

The Antiviral RNAi Response in Vector and Non-vector Cells against Orthobunyaviruses

scientific article

The Transcriptional and Protein Profile From Human Infected Neuroprogenitor Cells Is Strongly Correlated to Zika Virus Microcephaly Cytokines Phenotype Evidencing a Persistent Inflammation in the CNS

scientific article published on 16 August 2019

The circadian clock components BMAL1 and REV-ERBα regulate flavivirus replication

scientific article published in Nature Communications

The mosquito electrocuting trap as an exposure-free method for measuring human-biting rates by Aedes mosquito vectors

scientific article published on 15 January 2020

The type I interferon system protects mice from Semliki Forest virus by preventing widespread virus dissemination in extraneural tissues, but does not mediate the restricted replication of avirulent virus in central nervous system neurons

scientific article published in December 2007

Tick cell lines for study of Crimean-Congo hemorrhagic fever virus and other arboviruses

scientific article

Tick-borne encephalitis virus inhibits rRNA synthesis and host protein production in human cells of neural origin

scientific article published on 27 September 2019

Toxorhynchites Species: A Review of Current Knowledge

scientific article published on 30 October 2020

Transcriptome analysis reveals the host response to Schmallenberg virus in bovine cells and antagonistic effects of the NSs protein

scientific article published on 19 April 2015

Two Years into the COVID-19 Pandemic: Lessons Learned

scientific article published in 2022

Understanding the Wolbachia-mediated inhibition of arboviruses in mosquitoes: progress and challenges

scientific article published on 16 December 2013

Vector competence of Aedes vexans (Meigen), Culex poicilipes (Theobald) and Cx. quinquefasciatus Say from Senegal for West and East African lineages of Rift Valley fever virus

scientific article published on 20 February 2016

Wolbachia Blocks Viral Genome Replication Early in Infection without a Transcriptional Response by the Endosymbiont or Host Small RNA Pathways

scientific article

Worldwide survey reveals lower susceptibility of African Aedes aegypti mosquitoes to diverse strains of Zika virus

scholarly article published 10 June 2018

Zika Virus Infection Leads to Demyelination and Axonal Injury in Mature CNS Cultures

scientific article

Zika virus infection of glia leads to secondary injury to axons and dendrites

scientific article published in 2019

Zika virus tropism and interactions in myelinating neural cell cultures: CNS cells and myelin are preferentially affected

scientific article

Zika virus utilises the ubiquitin-proteasome pathway during infection of mosquito and human cells

scientific article published in 2019

Zika virus-like particles bearing covalent dimer of envelope protein protect mice from lethal challenge

scientific article published on 07 October 2020

Zika virus: a previously slow pandemic spreads rapidly through the Americas

scientific article

aBravo Is a Novel Aedes aegypti Antiviral Protein that Interacts with, but Acts Independently of, the Exogenous siRNA Pathway Effector Dicer 2

scientific article published on 11 July 2020

periscope: sub-genomic RNA identification in SARS-CoV-2 Genomic Sequencing Data

scientific article published in July 2020

viRome: an R package for the visualization and analysis of viral small RNA sequence datasets

scientific article published on 24 May 2013

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