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List of works by Aswin Mangerich

A Multi-Endpoint Approach to Base Excision Repair Incision Activity Augmented by PARylation and DNA Damage Levels in Mice: Impact of Sex and Age

scientific article published on 09 September 2020

A caveat in mouse genetic engineering: ectopic gene targeting in ES cells by bidirectional extension of the homology arms of a gene replacement vector carrying human PARP-1.

scientific article published on 26 November 2008

A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome

scientific article (publication date: 4 November 2014)

A mass spectrometric platform for the quantitation of sulfur mustard-induced nucleic acid adducts as mechanistically relevant biomarkers of exposure

scientific article published on 15 October 2018

A novel exposure system generating nebulized aerosol of sulfur mustard in comparison to the standard submerse exposure

scientific article published on 28 November 2018

An automated Fpg-based FADU method for the detection of oxidative DNA lesions and screening of antioxidants

scientific article

Chemical and cytokine features of innate immunity characterize serum and tissue profiles in inflammatory bowel disease

scientific article published on 10 June 2013

Chemical warfare in the First World War: reflections 100 years later.

scientific article published on 23 September 2014

Chemistry meets biology in colitis-associated carcinogenesis

scientific article

Comparison of Aristolochic acid I derived DNA adduct levels in human renal toxicity models

scientific article published on 30 March 2019

Day and night variations in the repair of ionizing-radiation-induced DNA damage in mouse splenocytes.

scientific article

Differential and Concordant Roles for Poly(ADP-Ribose) Polymerase 1 and Poly(ADP-Ribose) in Regulating WRN and RECQL5 Activities

scientific article published on 21 September 2015

How to kill tumor cells with inhibitors of poly(ADP-ribosyl)ation.

scientific article

Immunochemical analysis of poly(ADP-ribosyl)ation in HaCaT keratinocytes induced by the mono-alkylating agent 2-chloroethyl ethyl sulfide (CEES): Impact of experimental conditions.

scientific article published on 14 September 2015

Increased levels of inosine in a mouse model of inflammation

scientific article published on 04 April 2013

Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer

scientific article

Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1.

scientific article published on 8 June 2010

Interactions of p53 with poly(ADP-ribose) and DNA induce distinct changes in protein structure as revealed by ATR-FTIR spectroscopy

scientific article published on 01 May 2019

Mass spectrometric analysis of sulfur mustard-induced biomolecular adducts: Are DNA adducts suitable biomarkers of exposure?

scientific article published on 22 December 2017

Mechanisms of Hg species induced toxicity in cultured human astrocytes: genotoxicity and DNA-damage response

scientific article published on 19 February 2014

Mechanistic insights into the three steps of poly(ADP-ribosylation) reversal

scientific article published on 28 July 2021

Molecular mechanisms of Mn induced neurotoxicity: RONS generation, genotoxicity, and DNA‐damage response ⬇️

scientific article published on March 14, 2013

NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome

scientific article published on 21 November 2019

PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progression.

scientific article published on 9 April 2018

PARP1 protects from benzo[a]pyrene diol epoxide-induced replication stress and mutagenicity.

scientific article published in December 2017

PARP1 regulates DNA damage-induced nucleolar-nucleoplasmic shuttling of WRN and XRCC1 in a toxicant and protein-specific manner

scientific article published on 11 July 2019

Pleiotropic Cellular Functions of PARP1 in Longevity and Aging: Genome Maintenance Meets Inflammation ⬇️

scientific article published on September 19, 2012

Poly(ADP-ribose)-mediated interplay of XPA and PARP1 leads to reciprocal regulation of protein function.

scientific article

Quantification of cellular poly(ADP-ribosyl)ation by stable isotope dilution mass spectrometry reveals tissue- and drug-dependent stress response dynamics

scientific article published on 13 May 2013

Quantitation of Poly(ADP-Ribose) by Isotope Dilution Mass Spectrometry.

scientific article published in January 2017

Quantitative analysis of WRN exonuclease activity by isotope dilution mass spectrometry ⬇️

scientific article published on July 2, 2012

Real-time monitoring of PARP1-dependent PARylation by ATR-FTIR spectroscopy

scientific article published on 01 May 2020

RecQ helicases and PARP1 team up in maintaining genome integrity

scientific article

Restriction of AID activity and somatic hypermutation by PARP-1

scientific article published on 01 August 2019

Site-specific noncovalent interaction of the biopolymer poly(ADP-ribose) with the Werner syndrome protein regulates protein functions.

scientific article published on 29 October 2012

Sulfur and nitrogen mustards induce characteristic poly(ADP-ribosyl)ation responses in HaCaT keratinocytes with distinctive cellular consequences

scientific article published on 14 September 2015

The C-terminal domain of p53 orchestrates the interplay between non-covalent and covalent poly(ADP-ribosyl)ation of p53 by PARP1.

scientific article published on 4 December 2017

Toxicological properties of the thiolated inorganic arsenic and arsenosugar metabolite thio-dimethylarsinic acid in human bladder cells.

scientific article published on 5 July 2013

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