List of works by Gilla Kaplan

'Z(S)-MDR-TB' versus 'Z(R)-MDR-TB': improving treatment of MDR-TB by identifying pyrazinamide susceptibility

scientific article published on 25 July 2012

A Novel Molecular Strategy for Surveillance of Multidrug Resistant Tuberculosis in High Burden Settings

scientific article published on 11 January 2016

A combination of baseline plasma immune markers can predict therapeutic response in multidrug resistant tuberculosis

scientific article

A glycolipid of hypervirulent tuberculosis strains that inhibits the innate immune response

scientific article published in Nature

A metabolic biosignature of early response to anti-tuberculosis treatment

scientific article published on 31 January 2014

A multidrug-resistant, acr1-deficient clinical isolate of Mycobacterium tuberculosis is unimpaired for replication in macrophages

scientific article published on 11 May 2006

A new recombinant bacille Calmette-Guérin vaccine safely induces significantly enhanced tuberculosis-specific immunity in human volunteers

scientific article

A novel role for C-C motif chemokine receptor 2 during infection with hypervirulent Mycobacterium tuberculosis

scientific article published on 16 August 2018

A subset of circulating blood mycobacteria-specific CD4 T cells can predict the time to Mycobacterium tuberculosis sputum culture conversion

scientific article (publication date: 2014)

Adjunctive Phosphodiesterase-4 Inhibitor Therapy Improves Antibiotic Response to Pulmonary Tuberculosis in a Rabbit Model

scientific article published on 14 January 2016

Adjunctive thalidomide therapy for childhood tuberculous meningitis: results of a randomized study

scientific article

Advances in immunotherapy for tuberculosis treatment

scientific article published on December 2009

An analysis of in vitro T cell responsiveness in lepromatous leprosy

scientific article

Antibody profiles characteristic of Mycobacterium tuberculosis infection state

scientific article

Antigen-specific T lymphocytes efficiently cluster with dendritic cells in the human primary mixed-leukocyte reaction

scientific article published on 01 January 1988

Antiretroviral program associated with reduction in untreated prevalent tuberculosis in a South African township

scientific article

Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guérin

scientific article published on October 1994

Arginine usage in mycobacteria-infected macrophages depends on autocrine-paracrine cytokine signaling

scientific article

Association of TNF, MBL, and VDR polymorphisms with leprosy phenotypes

scientific article

Association of human TLR1 and TLR6 deficiency with altered immune responses to BCG vaccination in South African infants

scientific article

Author Correction: The wide utility of rabbits as models of human diseases

scientific article published on 04 July 2019

BCG Vaccination of Infants Confers Mycobacterium tuberculosis Strain-Specific Immune Responses by Leukocytes

scientific article published on 23 November 2020

BCG induces protection against Mycobacterium tuberculosis infection in the Wistar rat model

scientific article

BCG vaccination confers poor protection against M. tuberculosis HN878-induced central nervous system disease

scientific article published on 27 November 2006

Bacillus Calmette Guerin vaccination of human newborns induces a specific, functional CD8+ T cell response

scientific article published on 01 October 2006

Bacillus Calmette-Guérin vaccination of human newborns induces T cells with complex cytokine and phenotypic profiles

scientific article

Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism

scientific article

Cellular immune response to Mycobacterium leprae infection in human immunodeficiency virus-infected individuals.

scientific article

Cellular responses to the intradermal injection of recombinant human gamma-interferon in lepromatous leprosy patients

scientific article

Characterization of the divergent wound-healing responses occurring in the pathergy reaction and normal healthy volunteers.

scientific article published in November 2006

Chronic pulmonary cavitary tuberculosis in rabbits: a failed host immune response

scientific article published on December 2011

Coinfection of fibroblasts with Coxiella burnetti and Toxoplasma gondii: to each their own.

scientific article published on June 2000

Common polymorphisms in the NOD2 gene region are associated with leprosy and its reactive states

scientific article

Comparable growth of virulent and avirulent Mycobacterium tuberculosis in human macrophages in vitro

scientific article published on 01 July 1996

Construction and characterization of poliovirus subgenomic replicons

scientific article published on May 1988

Correlation of rpoB Mutations with Minimal Inhibitory Concentration of Rifampin and Rifabutin in Mycobacterium tuberculosis in an HIV/AIDS Endemic Setting, South Africa

scientific article published on 05 December 2016

Cutaneous leishmaniasis. The defect in T cell influx in BALB/c mice

scientific article

Cytokine gene activation and modified responsiveness to interleukin-2 in the blood of tuberculosis patients

scientific article published on 01 October 1993

Defective gamma interferon production in leprosy. Reversal with antigen and interleukin 2.

scientific article

Detection and treatment of subclinical tuberculosis

article

Detection of Mycobacterium tuberculosis in latently infected lungs by immunohistochemistry and confocal microscopy

scientific article published on 26 August 2014

Differential expression of iron-, carbon-, and oxygen-responsive mycobacterial genes in the lungs of chronically infected mice and tuberculosis patients

scientific article

Differential monocyte activation underlies strain-specific Mycobacterium tuberculosis pathogenesis

scientific article published on September 2004

Distribution and turnover of Langerhans cells during delayed immune responses in human skin

scientific article

Dose-dependent immune response to Mycobacterium bovis BCG vaccination in neonates

scientific article published on 20 December 2006

Down regulation of poliovirus receptor RNA in HeLa cells resistant to poliovirus infection

scientific article published on April 1991

Early innate immunity determines outcome of Mycobacterium tuberculosis pulmonary infection in rabbits

scientific article published on 19 August 2013

Effect of cutaneous cell-mediated immune response to rIFN gamma on Mycobacterium leprae viability in the lesions of lepromatous leprosy

scientific article published on 01 January 1992

Effect of standard tuberculosis treatment on plasma cytokine levels in patients with active pulmonary tuberculosis

scientific article (publication date: 2012)

Effective treatment of erythema nodosum leprosum with thalidomide is associated with immune stimulation

scientific article

Epidemiologic consequences of microvariation in Mycobacterium tuberculosis

scientific article

Etanercept exacerbates inflammation and pathology in a rabbit model of active pulmonary tuberculosis

scientific article

Evaluation of the Mtb72F polyprotein vaccine in a rabbit model of tuberculous meningitis

scientific article published on April 2006

Experimental tuberculosis in the Wistar rat: a model for protective immunity and control of infection

scientific article

Factors affecting tuberculosis strain success over 10 years in a high TB- and HIV-burdened community

scientific article

Frequency of Circulating CD4Ki67HLA-DR T Regulatory Cells Prior to Treatment for Multidrug Resistant Tuberculosis Can Differentiate the Severity of Disease and Predict Time to Culture Conversion

article

Function and regulation of class I ribonucleotide reductase-encoding genes in mycobacteria

scientific journal article

Functional capacity of Mycobacterium tuberculosis-specific T cell responses in humans is associated with mycobacterial load

scientific article

Gemfibrozil inhibits Legionella pneumophila and Mycobacterium tuberculosis enoyl coenzyme A reductases and blocks intracellular growth of these bacteria in macrophages

scientific article published on 08 May 2009

Genetic polymorphism in Mycobacterium tuberculosis isolates from patients with chronic multidrug-resistant tuberculosis

scientific article published on 28 May 2004

Genetic variation in TLR genes in Ugandan and South African populations and comparison with HapMap data

scientific article

H2O2 induces monocyte apoptosis and reduces viability of Mycobacterium avium-M. intracellulare within cultured human monocytes

scientific article

HIV-1 infection in infants severely impairs the immune response induced by Bacille Calmette-Guérin vaccine

scientific article

HIV-M. leprae interaction: can HAART modify the course of leprosy?

scientific article

HIV-specific gag responses in early infancy correlate with clinical outcome and inversely with viral load

scientific article published on 12 May 2011

Heterogeneous expression of poliovirus receptor-related proteins in human cells and tissues

scientific article published on November 1990

Host targeted activity of pyrazinamide in Mycobacterium tuberculosis infection

scientific article

Human TLR1 deficiency is associated with impaired mycobacterial signaling and protection from leprosy reversal reaction

scientific article

Human newborn bacille Calmette-Guérin vaccination and risk of tuberculosis disease: a case-control study

scientific article

Hypervirulent M. tuberculosis W/Beijing strains upregulate type I IFNs and increase expression of negative regulators of the Jak-Stat pathway

scientific article published in November 2005

Immunopathologic effects of tumor necrosis factor alpha in murine mycobacterial infection are dose dependent

scientific article published on December 2000

In Vivo Phenotypic Dominance in Mouse Mixed Infections withMycobacterium tuberculosisClinical Isolates

scientific article published on 07 July 2005

In vitro synthesis of infectious poliovirus RNA

scientific article published on December 1985

In vivo administration of low-dose human interleukin-2 induces lymphokine-activated killer cells for enhanced cytolysis in vitro

scientific article published on 01 February 1991

Induction of ER stress in macrophages of tuberculosis granulomas

scientific article

Induction of granulysin and perforin cytolytic mediator expression in 10-week-old infants vaccinated with BCG at birth

scientific article

Innate immune response to Mycobacterium tuberculosis Beijing and other genotypes

scientific article

Inoculum size and traits of the infecting clinical strain define the protection level against Mycobacterium tuberculosis infection in a rabbit model

scientific article published on 04 March 2020

Interleukin-10 (IL-10) in experimental visceral leishmaniasis and IL-10 receptor blockade as immunotherapy

scientific article

Interleukin-17 limits hypoxia-inducible factor 1α and development of hypoxic granulomas during tuberculosis

scientific article published on 5 October 2017

Intradermal recombinant interleukin 2 enhances peripheral blood T-cell responses to mitogen and antigens in patients with lepromatous leprosy

scientific article published on 01 August 1990

Isolation and characterization of HeLa cell lines blocked at different steps in the poliovirus life cycle

scientific article published on January 1989

Keratinocyte growth regulation by the products of immune cells

scientific article published on October 1988

Lesion-Specific Immune Response in Granulomas of Patients with Pulmonary Tuberculosis: A Pilot Study

scientific article published on 2 July 2015

Lessons of leprosy: the emergence of TH17 cytokines during type II reactions (ENL) is teaching us about T-cell plasticity

scientific article published on May 2012

Local and systemic effects of intradermal recombinant interferon-gamma in patients with lepromatous leprosy

scientific article published on 01 July 1986

Local nerve damage in leprosy does not lead to an impaired cellular immune response or decreased wound healing in the skin

scientific article published on 3 July 2002

Long-term dominance of Mycobacterium tuberculosis Uganda family in peri-urban Kampala-Uganda is not associated with cavitary disease

scientific article

Longitudinal changes in CD4(+) T-cell memory responses induced by BCG vaccination of newborns

scientific article published on 4 January 2013

Macrophage migration inhibitory factor (MIF) is a critical mediator of the innate immune response to Mycobacterium tuberculosis

scientific article published on 23 July 2013

Macrophages in tuberculosis: friend or foe.

scientific article published on 18 July 2013

Mechanism of in vitro synthesis of covalently linked dimeric RNA molecules by the poliovirus replicase

scientific article published on May 1986

Metformin as adjunct antituberculosis therapy

scientific article published on November 2014

Modulation of the cytokine response in human monocytes by mycobacterium leprae phenolic glycolipid-1.

scientific article published on 7 October 2011

Molecular epidemiology of Mycobacterium tuberculosis in a South African community with high HIV prevalence

scientific article

Molecular immunologic correlates of spontaneous latency in a rabbit model of pulmonary tuberculosis

scientific article published on 28 February 2013

Mutational analysis of upstream AUG codons of poliovirus RNA.

scientific article published on December 1988

Mycobacterial antigens exacerbate disease manifestations in Mycobacterium tuberculosis-infected mice

scientific article

Mycobacterial growth and sensitivity to H2O2 killing in human monocytes in vitro

scientific article

Mycobacterium leprae actively modulates the cytokine response in naive human monocytes

scientific article

Mycobacterium leprae alters classical activation of human monocytes in vitro

scientific article published on 11 March 2016

Mycobacterium leprae inhibits dendritic cell activation and maturation

scientific article published on 01 January 2007

Mycobacterium leprae-induced interferon-gamma production by household contacts of leprosy patients: association with the development of active disease

scientific article published on 01 November 1991

Mycobacterium tuberculosis 19-kilodalton lipoprotein inhibits Mycobacterium smegmatis-induced cytokine production by human macrophages in vitro

scientific article

Mycobacterium tuberculosis CDC1551 induces a more vigorous host response in vivo and in vitro, but is not more virulent than other clinical isolates

scientific article published on 01 June 1999

Mycobacterium tuberculosis H37Ra and H37Rv differential growth and cytokine/chemokine induction in murine macrophages in vitro.

scientific article published in January 2006

Mycobacterium tuberculosis catalase and peroxidase activities and resistance to oxidative killing in human monocytes in vitro

scientific article

Mycobacterium tuberculosis growth at the cavity surface: a microenvironment with failed immunity

scientific article

Mycobacterium tuberculosis inhibits maturation of human monocyte-derived dendritic cells in vitro

scientific article published on 9 July 2003

Neutralization of poliovirus by cell receptors expressed in insect cells

scientific article

Nonadherent cultures of human monocytes kill Mycobacterium smegmatis, but adherent cultures do not.

scientific article

Novel application of a whole blood intracellular cytokine detection assay to quantitate specific T-cell frequency in field studies.

scientific article published in August 2004

Perforin, a cytotoxic molecule which mediates cell necrosis, is not required for the early control of mycobacterial infection in mice

scientific article published on January 1997

Pharmacologic Inhibition of Host Phosphodiesterase-4 Improves Isoniazid-Mediated Clearance of Mycobacterium tuberculosis

scientific article published on 17 June 2016

Phosphodiesterase 4 inhibition reduces innate immunity and improves isoniazid clearance of Mycobacterium tuberculosis in the lungs of infected mice

scientific article

Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungs

scientific article published in September 2011

Phosphodiesterase-4 inhibition combined with isoniazid treatment of rabbits with pulmonary tuberculosis reduces macrophage activation and lung pathology

scientific article

Plasma interferon-gamma-inducible protein 10 can be used to predict viral load in HIV-1-infected individuals

scientific article published on July 2013

Prolonged immunostimulatory effect of low-dose polyethylene glycol interleukin 2 in patients with human immunodeficiency virus type 1 infection

scientific article

Prolonged treatment with recombinant interferon gamma induces erythema nodosum leprosum in lepromatous leprosy patients ⬇️

scientific article published on June 1, 1992

Qualification of a whole blood intracellular cytokine staining assay to measure mycobacteria-specific CD4 and CD8 T cell immunity by flow cytometry

scientific article

Quantitative and functional differences between peripheral blood myeloid dendritic cells from patients with pleural and parenchymal lung tuberculosis

scientific article

Rational vaccine development--a new trend in tuberculosis control

scientific article published in October 2005

Recognition and destruction of Bacillus Calmette-Guerin-infected human monocytes ⬇️

scientific article published on June 1, 1993

Recombinant interleukin 2 adjunctive therapy in multidrug-resistant tuberculosis.

scientific article published in January 1998

Regulation of acquired immunity by gamma delta T-cell/dendritic-cell interactions

scientific article published on 01 December 2005

Regulation of cell-mediated immunity in lepromatous leprosy

scientific article published on 01 December 1986

Ribonucleotide Reduction in Mycobacterium tuberculosis : Function and Expression of Genes Encoding Class Ib and Class II Ribonucleotide Reductases ⬇️

scientific article published on November 1, 2003

Role of the DinB homologs Rv1537 and Rv3056 in Mycobacterium tuberculosis

scientific article

Safety, tolerability, and pharmacokinetic effects of thalidomide in patients infected with human immunodeficiency virus: AIDS Clinical Trials Group 267.

scientific article

Sequestration of Mycobacterium tuberculosis in tight vacuoles in vivo in lung macrophages of mice infected by the respiratory route

scientific article published on January 1997

Significantly skewed memory CD8+ T cell subsets in HIV-1 infected infants during the first year of life

scientific article

Specific T cell frequency and cytokine expression profile do not correlate with protection against tuberculosis after bacillus Calmette-Guérin vaccination of newborns

scientific article published on 17 June 2010

Spontaneous latency in a rabbit model of pulmonary tuberculosis.

scientific article

Strain specific transcriptional response in Mycobacterium tuberculosis infected macrophages

scientific article published on 26 January 2012

Strain-specific mycobacterial lipids and the stimulation of protective immunity to tuberculosis

scientific article

Survival of Mycobacterium avium and Mycobacterium tuberculosis in acidified vacuoles of murine macrophages

scientific article

TB day summit in upstate New York: Key issues to address

scientific article published on 01 June 2009

Thalidomide and Phosphodiesterase 4 Inhibitors as Host Directed Therapeutics for Tuberculous Meningitis: Insights From the Rabbit Model

scientific article published on 01 January 2019

Thalidomide and a thalidomide analogue drug costimulate virus-specific CD8+ T cells in vitro

scientific article published on 6 March 2003

Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation

scientific article published on June 1993

Thalidomide in multiple myeloma--from the clinic to the laboratory

scientific article

Thalidomide in toxic epidermal necrolysis

scientific article published on 01 January 1999

Thalidomide induces granuloma differentiation in sarcoid skin lesions associated with disease improvement

scientific article published in March 2002

Thalidomide protects mice against LPS-induced shock

scientific article published on 01 October 1997

Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes

scientific article

Thalidomide treatment reduces tumor necrosis factor alpha production and enhances weight gain in patients with pulmonary tuberculosis

scientific article published on May 1995

The Influence of Thalidomide on the Clinical and Immunologic Manifestation of Erythema Nodosum Leprosum

scientific article published on 01 August 1993

The effect of bacille Calmette-Guérin vaccine strain and route of administration on induced immune responses in vaccinated infants

scientific article published on 13 January 2006

The expression of a gamma interferon-induced protein (IP-10) in delayed immune responses in human skin

scientific article published on October 1987

The generation of antigen-specific, major histocompatibility complex-restricted cytotoxic T lymphocytes of the CD4+ phenotype. Enhancement by the cutaneous administration of interleukin 2

scientific article

The nature and kinetics of a delayed immune response to purified protein derivative of tuberculin in the skin of lepromatous leprosy patients

scientific article

The phenolic glycolipid of Mycobacterium tuberculosis differentially modulates the early host cytokine response but does not in itself confer hypervirulence

scientific article published on 28 April 2008

The resuscitation-promoting factors of Mycobacterium tuberculosis are required for virulence and resuscitation from dormancy but are collectively dispensable for growth in vitro

scientific article

The role of MmpL8 in sulfatide biogenesis and virulence of Mycobacterium tuberculosis

scientific journal article

The role of RelMtb-mediated adaptation to stationary phase in long-term persistence of Mycobacterium tuberculosis in mice

scientific journal article

The selective binding and transmigration of monocytes through the junctional complexes of human endothelium

scientific article published on November 1988

The systemic influence of recombinant interleukin 2 on the manifestations of lepromatous leprosy

scientific article

The wide utility of rabbits as models of human diseases.

scientific article published on 22 May 2018

Toll-like receptor 2 (TLR2) polymorphisms are associated with reversal reaction in leprosy

scientific article

Toll-like receptor-induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

scientific article

Transcriptional profiling of mycobacterial antigen-induced responses in infants vaccinated with BCG at birth

scientific article

Translational Research for Tuberculosis Elimination: Priorities, Challenges, and Actions

scientific article

Translational efficiency of poliovirus mRNA: mapping inhibitory cis-acting elements within the 5' noncoding region

scientific article published on July 1988

Transmission of tuberculosis in a South African community with a high prevalence of HIV infection

scientific article

Tuberculosis control in crisis-causes and solutions

scientific article published on 15 October 2019

Tuberculosis research comes of age. Keystone Symposium on Tuberculosis: Molecular Mechanisms and Immunologic Aspects

scientific article published on 01 August 1998

Tuberculosis: integrating host and pathogen biology. A summary of the 2005 Keystone Symposia

scientific article published on 01 March 2006

Tumor necrosis factor alpha is a determinant of pathogenesis and disease progression in mycobacterial infection in the central nervous system

scientific article

Undiagnosed tuberculosis in a community with high HIV prevalence: implications for tuberculosis control

scientific article published on 14 September 2006

Use of IMiD3, a Thalidomide Analog, as an Adjunct to Therapy for Experimental Tuberculous Meningitis

scientific article published in 2002

Use of IMiD3, a thalidomide analog, as an adjunct to therapy for experimental tuberculous meningitis

scientific article

Virulence of a Mycobacterium tuberculosis clinical isolate in mice is determined by failure to induce Th1 type immunity and is associated with induction of IFN-alpha /beta

scientific article published on 24 April 2001

Virulence of selected Mycobacterium tuberculosis clinical isolates in the rabbit model of meningitis is dependent on phenolic glycolipid produced by the bacilli

scientific article

bis-Molybdopterin guanine dinucleotide is required for persistence of Mycobacterium tuberculosis in guinea pigs

scientific article

rhuIL-2 adjunctive therapy in multidrug resistant tuberculosis: a comparison of two treatment regimens and placebo

scientific article published on 01 January 1997

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