Search filters

List of works by Stephen Chambers

2-Aminoacetophenone as a potential breath biomarker for Pseudomonas aeruginosa in the cystic fibrosis lung

scientific article

A Novel Monoclonal Antibody 1D2 That Broadly Inhibits Clinically Important Aspergillus Species

scientific article published in 2022

A persuasive approach to antimicrobial stewardship in Christchurch hospitals produced a sustained decrease in intravenous clarithromycin dosing and expenditure via a switch to azithromycin orally

scientific article published on 3 April 2020

A prospective double-blind randomized trial comparing intraluminal ethanol with heparinized saline for the prevention of catheter-associated bloodstream infection in immunosuppressed haematology patients.

scientific article published on 11 July 2008

ACE and ACE2 in inflammation: a tale of two enzymes

scientific article published on January 2014

AIDS in New Zealand

scientific article published on 02 April 2004

Abnormal glycine betaine content of the blood and urine of diabetic and renal patients

scientific article published on 01 October 1994

Adaptive resistance following single doses of gentamicin in a dynamic in vitro model.

scientific article

Adaptive resistance to tobramycin in Pseudomonas aeruginosa lung infection in cystic fibrosis

scientific article published on 01 June 1996

Alteration of the renin-angiotensin system in caerulein induced acute pancreatitis in the mouse.

scientific article published on 28 September 2015

An abnormal urinary excretion of glycine betaine may persist for years

scientific article published on 28 March 2007

An audit of venous duplex ultrasonography in patients with lower limb cellulitis

scientific article published on February 11, 2011

Antibiotic resistance in uncomplicated urinary tract infection: problems with interpreting cumulative resistance rates from local community laboratories.

scientific article

Antimicrobial Treatment Options for Granulomatous Mastitis Caused by Corynebacterium Species

scientific article published in July 2015

Antimicrobial effects of lomefloxacin in vitro

scientific article published on 01 April 1991

Antimicrobial stewardship practice in New Zealand's rural hospitals

scientific article published on 31 August 2018

Antimicrobial susceptibilities of clinical Legionella longbeachae isolates

scientific article published on 19 December 2017

Assessment of antimicrobial activity of hydrophilic betaines in osmotically stressed bacteria.

scientific article published on January 2003

Assessment of potential causes of falsely positive Mycobacterium tuberculosis breath test.

scientific article published on 13 March 2013

Association between HACEK bacteraemia and endocarditis

scientific article

Atypical pneumonia--time to breathe new life into a useful term?

scientific article

Bacterial killing by neutrophils in hypertonic environments.

scientific article

Betaine analogues alter homocysteine metabolism in rats

scientific article published in May 2004

Betaine and Trimethylamine-N-Oxide as Predictors of Cardiovascular Outcomes Show Different Patterns in Diabetes Mellitus: An Observational Study

scientific article

Betaine and secondary events in an acute coronary syndrome cohort

scientific article

Betaine excretion correlates with plasma homocysteine when plasma lipids are elevated

scientific article published on 07 November 2011

Betaine supplementation decreases post-methionine hyperhomocysteinemia in chronic renal failure

scientific article published in March 2002

Betaines and urinary tract infections

scientific article published on 01 January 1996

Biofilm Inhibition via Delivery of Novel Methylthioadenosine Nucleosidase Inhibitors from PVA-Tyramine Hydrogels while Supporting Mesenchymal Stromal Cell Viability

scientific article published on 10 January 2019

Biomarkers of cardiac dysfunction and mortality from community-acquired pneumonia in adults

scientific article

Campylobacter fetus prosthetic hip joint infection: successful management with device retention and review.

scientific article

Campylobacter fetus-associated epidural abscess and bacteremia

scientific article published on 14 January 2009

Chlamydia trachomatis testing sensitivity in midstream compared with first-void urine specimens

scientific article published in January 2012

Ciguatera fish poisoning

scientific article published on 01 November 1999

Circulating levels of hydrogen sulfide and substance P in patients with sepsis

scientific article

Clinical presentation, etiology, and outcome of infective endocarditis in the 21st century: the International Collaboration on Endocarditis-Prospective Cohort Study

scientific article published on 9 March 2009

Community-acquired pneumonia: influence of management practices on length of hospital stay.

scientific article published on March 2004

Comparison of PCR-ELISA and galactomannan detection for the diagnosis of invasive aspergillosis.

scientific article

Comparison of galactomannan detection, PCR-enzyme-linked immunosorbent assay, and real-time PCR for diagnosis of invasive aspergillosis in a neutropenic rat model and effect of caspofungin acetate

scientific article

Comparison of gentamicin dosing regimens using an in-vitro model.

scientific article published in April 1992

Competitive accumulation of betaines by Escherichia coli K-12 and derivative strains lacking betaine porters.

scientific article

Complete Genome Sequence of a Legionella longbeachae Serogroup 2 Isolate Derived from a Patient with Legionnaires' Disease

scientific article published on 30 January 2020

Concomitant Staphylococcus aureus bacteriuria is associated with poor clinical outcome in adults with S. aureus bacteraemia.

scientific article published on 03 July 2008

Consensus guidelines for the treatment of invasive mould infections in haematological malignancy and haemopoietic stem cell transplantation, 2014.

scientific article

Contamination of Qiagen DNA extraction kits with Legionella DNA.

scientific article published on July 2003

Correction: Cystathionine-Gamma-Lyase Gene Deletion Protects Mice against Inflammation and Liver Sieve Injury following Polymicrobial Sepsis

scientific article published on 10 August 2017

Cutaneous larva migrans (hookworm) acquired in Christchurch, New Zealand

scientific article published on 31 March 2006

Cutaneous myiasis due to Dermatobia hominis (the human botfly) in a New Zealand traveller returned from South America.

scientific article published on 11 September 2009

Cystathionine-Gamma-Lyase Gene Deletion Protects Mice against Inflammation and Liver Sieve Injury following Polymicrobial Sepsis

scientific article

Cystathionine-Gamma-Lyase-Derived Hydrogen Sulfide-Regulated Substance P Modulates Liver Sieve Fenestrations in Caecal Ligation and Puncture-Induced Sepsis

scientific article published on 29 June 2019

Cystathionine-gamma-lyase gene silencing with siRNA in monocytes/macrophages protects mice against acute pancreatitis

scientific article published on 28 September 2015

Cystathionine-γ-lyase gene silencing with siRNA in monocytes/ macrophages attenuates inflammation in cecal ligation and puncture-induced sepsis in the mouse.

scientific article

Detection of 2-pentylfuran in the breath of patients with Aspergillus fumigatus. ⬇️

scientific article published in January 2009

Detection of Legionella DNA in guinea pig peripheral leukocytes, urine and plasma by the polymerase chain reaction

scientific article published on 01 June 1999

Determinants of vancomycin nephrotoxicity when administered to outpatients as a continuous 24 hour infusion

scientific article published on 13 April 2020

Determining the limits and confounders for the 2-pentyl furan breath test by gas chromatography/mass spectrometry

scientific article published on 17 August 2011

Developments in novel breath tests for bacterial and fungal pulmonary infection.

scientific article published on May 2012

Diagnosis and management of Staphylococcus aureus infections of the skin and soft tissue.

scientific article

Diagnosis and management of staphylococcal infections of pacemakers and cardiac defibrillators.

scientific article

Diagnosis and management of staphylococcal infections of vascular grafts and stents.

scientific article

Diagnosis of aspergillus peritonitis in a renal dialysis patient by PCR and galactomannan detection.

scientific article published on June 2004

Dietary and supplementary betaine: acute effects on plasma betaine and homocysteine concentrations under standard and postmethionine load conditions in healthy male subjects ⬇️

scientific article published on 01 March 2008

Dietary and supplementary betaine: effects on betaine and homocysteine concentrations in males.

scientific article published on 5 April 2009

Differential Effects of Kupffer Cell Inactivation on Inflammation and The Liver Sieve Following Caecal-Ligation and Puncture-Induced Sepsis in Mice

scientific article

Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations ⬇️

scientific article published on 27 December 2004

Dimethylglycine supplementation does not affect plasma homocysteine concentrations in pre-dialysis chronic renal failure patients.

scientific article published in November 2004

Dimethylthetin can substitute for glycine betaine as an osmoprotectant molecule for Escherichia coli.

scientific article

Dimethylthetin treatment causes diffuse alveolar lung damage: a pilot study in a sheep model of Continuous Ambulatory Peritoneal Dialysis (CAPD)

scientific article published on 18 December 2006

Effect of TNP on the microbiology of venous leg ulcers: a pilot study

scientific article

Effect of adjunctive single high-dose vitamin D on outcome of community-acquired pneumonia in hospitalised adults: The VIDCAPS randomised controlled trial

scientific article published in Scientific Reports

Effect of monthly vitamin D3 supplementation in healthy adults on adverse effects of earthquakes: randomised controlled trial

scientific article

Effect of vitamin D3 supplementation on Staphylococcus aureus nasal carriage: a randomized, double-blind, placebo-controlled trial in healthy adults

scientific article published on 04 September 2013

Effect of vitamin D3 supplementation on upper respiratory tract infections in healthy adults: the VIDARIS randomized controlled trial

scientific article

Effects of betaines and urine on the antibacterial activity of aminoglycosides.

scientific article

Effects of orange juice and proline betaine on glycine betaine and homocysteine in healthy male subjects.

scientific article published on 4 December 2007

Efficacies of different vancomycin dosing regimens against Staphylococcus aureus determined with a dynamic in vitro model.

scientific article published on October 1994

Enhanced detection of Legionnaires' disease by PCR testing of induced sputum and throat swabs

scientific article

Enhancement of culture of Legionella longbeachae from respiratory samples using immunomagnetic separation and antimicrobial decontamination

scientific article published on 12 August 2020

Enteric colonization with antibiotic resistant bacteria in nurses working in intensive care units.

scientific article

Epsilonproteobacteria in humans, New Zealand.

scientific article published on March 2012

Erratum to: Plasma betaine concentrations correlate with plasma cortisol but not with C-reactive protein in an elderly population

scientific article published on 12 September 2017

Evaluation of a PCR assay for detection of Streptococcus pneumoniae in respiratory and nonrespiratory samples from adults with community-acquired pneumonia

scientific article

Extreme urinary betaine losses in type 2 diabetes combined with bezafibrate treatment are associated with losses of dimethylglycine and choline but not with increased losses of other osmolytes

scientific article published on 01 October 2014

Fenofibrate causes elevation of betaine excretion but not excretion of other osmolytes by healthy adults

scientific article published on 16 April 2014

Fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine

scientific article published in October 2009

Fibrates plus betaine: a winning combination?

scientific article published on October 15, 2010

Free and total cefazolin plasma and interstitial fluid concentrations at steady state during continuous infusion

scientific article published in September 2002

Genetic polymorphism rs6922269 in the MTHFD1L gene is associated with survival and baseline active vitamin B12 levels in post-acute coronary syndromes patients

scientific article

Global polio eradication: progress, but determination and vigilance still needed

scientific article published on June 24, 2011

Glycine betaine excretion is not directly linked to plasma glucose concentrations in hyperglycaemia.

scientific article published in June 2001

HACEK infective endocarditis: characteristics and outcomes from a large, multi-national cohort

scientific article published in 2013

Home intravenous antimicrobial service--twelve months experience in Christchurch

scientific article

Homocysteine, glycine betaine, and N,N-dimethylglycine in patients attending a lipid clinic.

scientific article published in January 2005

Hormone and haemodynamic effects of angiotensin II infusion during captopril treatment for heart failure

scientific article published on 1 March 1985

How vancomycin is used in Australasia - A survey

scientific article published on 01 December 1993

Hydrogen Sulfide and Substance P Levels in Patients with Escherichia coli and Klebsiella pneumoniae Bacteraemia

scientific article published in 2022

Hypoglycaemia following removal of phaeochromocytoma: case report and review of the literature

scientific article published in August 1982

Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes.

scientific article

Impact of routine systematic polymerase chain reaction testing on case finding for Legionnaires' disease: a pre-post comparison study

scientific article published on 29 July 2013

In healthy volunteers, taking flucloxacillin with food does not compromise effective plasma concentrations in most circumstances.

scientific article

Incidence and characteristics of viral community-acquired pneumonia in adults.

scientific article

Increased rates of trimethoprim resistance in uncomplicated urinary tract infection: cause for concern?

scientific article

Indwelling urinary catheters in the elderly. Relation of "catheter life" to formation of encrustations in patients with and without blocked catheters

scientific article published on 01 March 1987

Infectious diseases--far from defeated

scientific article published on 20 August 2004

Infective endocarditis in New Zealand: data from the International Collaboration on Endocarditis Prospective Cohort Study

scientific article

Inhibition of hydrogen sulfide production by gene silencing attenuates inflammatory activity by downregulation of NF-κB and MAP kinase activity in LPS-activated RAW 264.7 cells.

scientific article published on 19 August 2014

Inhibitors of bacterial growth in urine: what is the role of betaines?

scientific article published in May 1999

Inter- and intra-individual variations in normal urinary glycine betaine excretion

scientific article published on 13 January 2007

Invasive aspergillosis in severely neutropenic patients over 18 years: impact of intranasal amphotericin B and HEPA filtration

scientific article published on 01 January 1998

Investigation into the production of 2-Pentylfuran by Aspergillus fumigatus and other respiratory pathogens in vitro and human breath samples

scientific article

Is N,N-dimethylglycine N-oxide a choline and betaine metabolite?

scientific article published on 01 June 2017

Is the ability of urinary tract pathogens to accumulate glycine betaine a factor in the virulence of pathogenic strains?

scientific article published on 01 October 1996

Klebsiella oxytoca revealing decreased susceptibility to extended spectrum beta-lactams

scientific article published on 01 July 1995

Legionnaires' disease caused by Legionella longbeachae: Clinical features and outcomes of 107 cases from an endemic area

scientific article published on 19 May 2016

Leprosy in New Zealand

scientific article published on 15 May 2015

Leprosy in the South Pacific

Long-term high-dose vitamin D3 supplementation and blood pressure in healthy adults: a randomized controlled trial

scientific article published on 30 June 2014

Metronidazole stewardship initiative at Christchurch hospitals-achievable with immediate benefits

scientific article

Māori have a much higher incidence of community-acquired pneumonia and pneumococcal pneumonia than non-Māori: findings from two New Zealand hospitals

scientific article published on 19 May 2006

Native Joint Septic Arthritis: Epidemiology, Clinical Features, and Microbiological Causes in a New Zealand Population

scientific article published in November 2015

Natural and synthetic betaines counter the effects of high NaCl and urea concentrations.

scientific article

Novel diagnostics: progress toward a breath test for invasive Aspergillus fumigatus.

scientific article published on 26 August 2010

Organic osmolytes in human and other mammalian kidneys

scientific article published on 01 February 1993

Osmoprotective activity, urea protection, and accumulation of hydrophilic betaines in Escherichia coli and Staphylococcus aureus

scientific article published on 01 April 1999

Outcomes of infected abdominal aortic grafts managed with antimicrobial therapy and graft retention in an unselected cohort.

scientific article published on April 2013

Outpatient intravenous treatment for infective endocarditis: safety, effectiveness and one-year outcomes.

scientific article published on 17 September 2009

Patient acceptability of home intravenous antibiotic therapy

scientific article published on 23 April 2004

Patients Undergoing Myeloablative Chemotherapy and Hematopoietic Stem Cell Transplantation Exhibit Depleted Vitamin C Status in Association with Febrile Neutropenia

scientific article published on 24 June 2020

Patients with Community Acquired Pneumonia Exhibit Depleted Vitamin C Status and Elevated Oxidative Stress

scientific article published on 06 May 2020

Peritonsillar infection in Christchurch 2006-2008: epidemiology and microbiology

scientific article published on June 24, 2011

Pine Species Provide a Niche for <i>Legionella Longbeachae</i>

scientific article published on 03 November 2020

Plasma and urine betaine and dimethylglycine variation in healthy young male subjects

scientific article published on 13 February 2009

Plasma betaine concentrations correlate with plasma cortisol but not with C-reactive protein in an elderly population

scientific article published on 18 March 2012

Plasma lipids and betaine are related in an acute coronary syndrome cohort

scientific article

Point prevalence surveys of antimicrobial use in adult inpatients at Canterbury District Health Board Hospitals

scientific article published on 20 November 2020

Politicians: please work together to minimise the spread of COVID-19

scientific article published on 13 March 2020

Population-based epidemiology of Staphylococcus aureus bloodstream infection in Canterbury, New Zealand

scientific article

Potential sources of 2-aminoacetophenone to confound the Pseudomonas aeruginosa breath test, including analysis of a food challenge study.

scientific article published on 23 June 2011

Predicting the impact of household contact and mass chemoprophylaxis on future new leprosy cases in South Tarawa, Kiribati: A modelling study

scientific article published on 20 September 2019

Prevalence of concurrent deep vein thrombosis in patients with lower limb cellulitis: a prospective cohort study

scientific article

Probenecid and food effects on flucloxacillin pharmacokinetics and pharmacodynamics in healthy volunteers

scientific article published on 12 September 2019

Protein binding of cefazolin is saturable in vivo both between and within patients

scientific article

Quantification of hydrogen cyanide (HCN) in breath using selected ion flow tube mass spectrometry--HCN is not a biomarker of Pseudomonas in chronic suppurative lung disease

scientific article published on 27 February 2013

Randomised controlled trial of intravenous antibiotic treatment for cellulitis at home compared with hospital

scientific article

Real-time detection of common microbial volatile organic compounds from medically important fungi by Selected Ion Flow Tube-Mass Spectrometry (SIFT-MS).

scientific article published in November 2005

Recurrent breast abscess caused by Gordonia bronchialis in an immunocompetent patient

scientific article

Recurrent orf in an immunocompromised host

scientific article published on 01 August 1991

Relationship between osmoprotection and the structure and intracellular accumulation of betaines by<i>Escherichia coli</i>

scientific article published in 1994

Reply to Boethel et al

scientific article published on 29 July 2014

Response to antibiotics of women with symptoms of urinary tract infection but negative dipstick urine test results: double blind randomised controlled trial

scientific article

Same-day batch measurement of glycine betaine, carnitine, and other betaines in biological material

scientific article published on 01 August 1992

Schistosomiasis at Christchurch Hospital, 1989-94

scientific article published on 01 April 1996

Sex differences in the control of plasma concentrations and urinary excretion of glycine betaine in patients attending a lipid disorders clinic

scientific article published on 17 July 2007

Short and long-term variation of plasma glycine betaine concentrations in humans

scientific article published in March 2004

Stability of benzylpenicillin during continuous home intravenous therapy

scientific article published on 10 March 2004

Staphylococcus aureus Carriage in a New Zealand Primary School: A Cohort Study

scientific article published on 22 September 2017

Successful antimicrobial therapy and implant retention for streptococcal infection of prosthetic joints

scientific article published in April 2004

Successful management of pain syndrome due to Angiostrongylus cantonensis by implantable spinal cord stimulator

scientific article published on 01 August 1999

Successful treatment with lamivudine for fulminant reactivated hepatitis B infection following intensive therapy for high-grade non-Hodgkin's lymphoma

scientific article published on 01 April 1998

Surveillance of Leprosy in Kiribati, 1935-2017

scientific article published on 1 May 2020

The association between colicinogenicity and pathogenesis among uropathogenic isolates of Escherichia coli

scientific article published on 01 March 1996

The burden of Legionnaires' disease in New Zealand (LegiNZ): a national surveillance study

scientific article published on 10 June 2019

The contrasting relationships between betaine and homocysteine in two clinical cohorts are associated with plasma lipids and drug treatments

scientific article

The dosing and monitoring of vancomycin: what is the best way forward?

scientific article published on 29 December 2018

The effect of aminoglycoside-induced adaptive resistance on the antibacterial activity of other antibiotics against Pseudomonas aeruginosa in vitro

scientific article published on 01 November 1996

The osmoprotective properties of urine for bacteria: the protective effect of betaine and human urine against low pH and high concentrations of electrolytes, sugars, and urea.

scientific article published in December 1985

The scent of Mycobacterium tuberculosis--part II breath.

scientific article published on 29 May 2009

The scent of Mycobacterium tuberculosis.

scientific article

Total flucloxacillin plasma concentrations poorly reflect unbound concentrations in hospitalized patients with Staphylococcus aureus bacteraemia

scientific article published on 20 July 2018

Treatment of Staphylococcus epidermidis central vascular catheter infection with 70% ethanol locks: efficacy in a sheep model.

scientific article published on 5 February 2007

Trigonelline is not responsible for the acute increase in plasma homocysteine following ingestion of instant coffee.

scientific article published in September 2004

Unbound Vitamin D Concentrations Are Not Decreased in Critically Ill Patients

scientific article published on 11 October 2020

Urinary tract infection in adults: research priorities and strategies

scientific article published in April 2001

Use of ethanol locks to prevent recurrent central line sepsis

scientific article

Use of the polymerase chain reaction to detect Legionella DNA in urine and serum samples from patients with pneumonia

scientific article published on 01 September 1996

Validating a breath collection and analysis system for the new tuberculosis breath test

scientific article published on 18 July 2013

Variability of plasma and urine betaine in diabetes mellitus and its relationship to methionine load test responses: an observational study.

scientific article

Variation of betaine, N,N-dimethylglycine, choline, glycerophosphorylcholine, taurine and trimethylamine-N-oxide in the plasma and urine of overweight people with type 2 diabetes over a two-year period.

scientific article

Paulina is supported by:

About Paulina

Help