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List of works by Alberto Alape-Girón

A cellular UDP-glucose deficiency causes overexpression of glucose/oxygen-regulated proteins independent of the endoplasmic reticulum stress elements.

scientific article published on 12 March 2004

A cellular deficiency of gangliosides causes hypersensitivity to Clostridium perfringens phospholipase C.

scientific article

A point mutation in the UDP-glucose pyrophosphorylase gene results in decreases of UDP-glucose and inactivation of glycogen synthase.

scientific article published on March 2003

Amino acid sequence and crystal structure of BaP1, a metalloproteinase from Bothrops asper snake venom that exerts multiple tissue-damaging activities

scientific article

Antibody-mediated neutralization and binding-reversal studies on α-neurotoxins from micrurus nigrocinctus nigrocinctus (coral snake) venom

scientific article published on 01 March 1996

Bacterial Sphingomyelinases and Phospholipases as Virulence Factors

scientific article

Biological models in multiple sclerosis

scientific article published on 01 October 2019

Cellular UDP-glucose deficiency caused by a single point mutation in the UDP-glucose pyrophosphorylase gene.

scientific article

Clostridium perfringens phospholipase C induced ROS production and cytotoxicity require PKC, MEK1 and NFκB activation

scientific article published on 23 January 2014

Comparison of a nontoxic variant of Clostridium perfringens α-toxin with the toxic wild-type strain

scientific article

Cross-reactivity, antivenomics, and neutralization of toxic activities of Lachesis venoms by polyspecific and monospecific antivenoms

scientific article published on 07 August 2017

Deficient Skeletal Muscle Regeneration after Injury Induced by a Clostridium perfringens Strain Associated with Gas Gangrene

scientific article published on 23 July 2019

Development of a new polyspecific antivenom for snakebite envenoming in Sri Lanka: Analysis of its preclinical efficacy as compared to a currently available antivenom

scientific article published on 6 October 2016

Development of immunoassays for determination of circulating venom antigens during envenomations by coral snakes (Micrurus species)

article

Effects of Clostridium perfringens phospholipase C in mammalian cells

scientific article published in April 2004

Effects of bilayer composition and physical properties on the phospholipase C and sphingomyelinase activities of Clostridium perfringens α-toxin

scientific article

Electrophoretic and immunochemical studies of Micrurus snake venoms

scientific article published on 01 June 1994

Epidemiology of snakebites in El Salvador (2014-2019)

scientific article published on 30 July 2020

Expanding the neutralization scope of the EchiTAb-plus-ICP antivenom to include venoms of elapids from Southern Africa

scientific article

Identification of B cell recognized linear epitopes in a snake venom serine proteinase from the central American bushmaster Lachesis stenophrys.

scientific article published on 27 October 2017

Identification of Residues in the Carboxy-Terminal Domain of Clostridium perfringens α-Toxin (Phospholipase C) Which Are Required for Its Biological Activities

scientific article published on 01 December 2000

Identification of residues critical for toxicity in Clostridium perfringens phospholipase C, the key toxin in gas gangrene.

scientific article published on August 2000

Immunization with cDNA of a novel P-III type metalloproteinase from the rattlesnake Crotalus durissus durissus elicits antibodies which neutralize 69% of the hemorrhage induced by the whole venom.

scientific article published on 13 June 2008

Immunochemical characterization of Micrurus nigrocinctus nigrocinctus venom with monoclonal and polyclonal antibodies

scientific article published on 01 June 1994

Impact of regional variation in Bothrops asper snake venom on the design of antivenoms: integrating antivenomics and neutralization approaches

scientific article published in January 2010

Internalization of Clostridium perfringens α-toxin leads to ERK activation and is involved on its cytotoxic effect

scientific article published on 13 December 2013

Isolation, characterization and molecular cloning of AnMIP, a new α-type phospholipase A2 myotoxin inhibitor from the plasma of the snake Atropoides nummifer (Viperidae: Crotalinae)

scientific article published on 26 September 2006

Lemnitoxin, the major component of Micrurus lemniscatus coral snake venom, is a myotoxic and pro-inflammatory phospholipase A2.

scientific article published on 6 June 2016

Neutralization of venom-induced hemorrhage by equine antibodies raised by immunization with a plasmid encoding a novel P-II metalloproteinase from the lancehead pitviper Bothrops asper.

scientific article published on 12 November 2008

Ocatin. A novel tuber storage protein from the andean tuber crop oca with antibacterial and antifungal activities

scientific article published in April 2002

Phospholipase C and sphingomyelinase activities of the Clostridium perfringens alpha-toxin

scientific article

Profiling the venom gland transcriptomes of Costa Rican snakes by 454 pyrosequencing

scientific article

Reactive oxygen species and the MEK/ERK pathway are involved in the toxicity of clostridium perfringens α-toxin, a prototype bacterial phospholipase C.

scientific article published on 16 August 2012

Role of Clostridium perfringens phospholipase C in the pathogenesis of gas gangrene

scientific article published on December 2003

Snake venomics across genus Lachesis. Ontogenetic changes in the venom composition of Lachesis stenophrys and comparative proteomics of the venoms of adult Lachesis melanocephala and Lachesis acrochorda

article

Snake venomics and antivenomics of Bothrops colombiensis, a medically important pitviper of the Bothrops atrox-asper complex endemic to Venezuela: Contributing to its taxonomy and snakebite management

scientific article

Snake venomics and antivenomics: Proteomic tools in the design and control of antivenoms for the treatment of snakebite envenoming

scientific article published on 21 January 2009

Snake venomics of Lachesis muta rhombeata and genus-wide antivenomics assessment of the paraspecific immunoreactivity of two antivenoms evidence the high compositional and immunological conservation across Lachesis

scientific article published on 4 June 2013

Snake venomics of the Central American rattlesnake Crotalus simus and the South American Crotalus durissus complex points to neurotoxicity as an adaptive paedomorphic trend along Crotalus dispersal in South America

scientific article

Snake venomics of the lancehead pitviper Bothrops asper: geographic, individual, and ontogenetic variations.

scientific article published on 17 June 2008

Structural characterization and phylogenetic relationships of myotoxin II from Atropoides (Bothrops) nummifer snake venom, a Lys49 phospholipase A(2) homologue

scientific article

Studies on the venom proteome of Bothrops asper: perspectives and applications

scientific article

The NanI and NanJ sialidases of Clostridium perfringens are not essential for virulence

scientific article published on 03 August 2009

Unexpected wide substrate specificity of C. perfringens α-toxin phospholipase C

scientific article published on 24 June 2011

Venomic and antivenomic analyses of the Central American coral snake, Micrurus nigrocinctus (Elapidae).

scientific article published on 25 February 2011

Venoms of Micrurus coral snakes: Evolutionary trends in compositional patterns emerging from proteomic analyses.

scientific article published on 15 September 2016

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