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List of works by Feng Lan

A net-shaped multicellular formation facilitates the maturation of hPSC-derived cardiomyocytes through mechanical and electrophysiological stimuli

scientific article published on 14 April 2018

AMPKα2 knockout enhances tumour inflammation through exacerbated liver injury and energy deprivation-associated AMPKα1 activation

scientific article published on 12 January 2019

Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells

scientific article

Adenovirus-mediated CTLA4Ig gene transfer improves the survival of grafted human hepatic progenitors in mouse liver

article

An episomal vector-based CRISPR/Cas9 system for highly efficient gene knockout in human pluripotent stem cells

scientific article (publication date: 24 May 2017)

Ascorbic acid can promote the generation and expansion of neuroepithelial-like stem cells derived from hiPS/ES cells under chemically defined conditions through promoting collagen synthesis

scientific article published on 09 January 2021

Author Correction: An episomal vector-based CRISPR/Cas9 system for highly efficient gene knockout in human pluripotent stem cells

scientific article published in Scientific Reports

CD40L promotes development of acute aortic dissection via induction of inflammation and impairment of endothelial cell function

scientific article published on 4 March 2018

Changes in the Hemostatic System of Patients With Acute Aortic Dissection Undergoing Aortic Arch Surgery.

scientific article

Chemically defined generation of human cardiomyocytes

scientific article

Chlorogenic acid: A potent molecule that protects cardiomyocytes from TNF-α-induced injury via inhibiting NF-κB and JNK signals

scientific article published on 29 April 2019

Disruption of mechanical stress in extracellular matrix is related to Stanford type A aortic dissection through down-regulation of Yes-associated protein

scientific article published on 05 September 2016

Downregulation of the Yes-Associated Protein Is Associated with Extracellular Matrix Disorders in Ascending Aortic Aneurysms.

scientific article published on 20 January 2016

Doxorubicin-induced cardiotoxicity is maturation dependent due to the shift from topoisomerase IIα to IIβ in human stem cell derived cardiomyocytes

scientific article published on 20 May 2019

Early stem cell engraftment predicts late cardiac functional recovery: preclinical insights from molecular imaging

scientific article

Effect of human donor cell source on differentiation and function of cardiac induced pluripotent stem cells

scientific article

Epigenetic Regulation of Phosphodiesterases 2A and 3A Underlies Compromised β-Adrenergic Signaling in an iPSC Model of Dilated Cardiomyopathy.

scientific article

Establishing a deeper understanding of the osteogenic differentiation of monolayer cultured human pluripotent stem cells using novel and detailed analyses

scientific article published on 07 January 2021

Genome editing of human embryonic stem cells and induced pluripotent stem cells with zinc finger nucleases for cellular imaging.

scientific article

Genome editing of isogenic human induced pluripotent stem cells recapitulates long QT phenotype for drug testing

scientific article

Human AML-iPSCs Reacquire Leukemic Properties after Differentiation and Model Clonal Variation of Disease.

scientific article published on 26 December 2016

Human cardiac progenitor cells engineered with Pim-I kinase enhance myocardial repair.

scientific article

In vivo gamma imaging of the secondary tumors of transplanted human fetal striatum neural stem cells-derived primary tumor cells.

scientific article published in July 2008

Induction of mutant p53-dependent apoptosis in human hepatocellular carcinoma by targeting stress protein mortalin.

scientific article published on 4 March 2011

Liensinine- and Neferine-Induced Cardiotoxicity in Primary Neonatal Rat Cardiomyocytes and Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

scientific article published on 29 January 2016

MLP-deficient human pluripotent stem cell derived cardiomyocytes develop hypertrophic cardiomyopathy and heart failure phenotypes due to abnormal calcium handling

scientific article published on 13 August 2019

MMP-2 gene polymorphisms are associated with type A aortic dissection and aortic diameters in patients

scientific article published on October 2016

MicroRNA-302 increases reprogramming efficiency via repression of NR2F2.

scientific article

Microscale grooves regulate maturation development of hPSC-CMs by the transient receptor potential channels (TRP channels)

scientific article published on 10 March 2021

Mortalin-p53 interaction in cancer cells is stress dependent and constitutes a selective target for cancer therapy

scientific article

Noninvasive measurement of regional pulse wave velocity in human ascending aorta with ultrasound imaging: an in-vivo feasibility study

scientific article published on 27 July 2016

Optimized CRISPR guide RNA design for two high-fidelity Cas9 variants by deep learning

scientific article published on 19 September 2019

Overexpression of CD133 promotes the phosphorylation of Erk in U87MG human glioblastoma cells

scientific article published on August 26, 2010

Preclinical derivation and imaging of autologously transplanted canine induced pluripotent stem cells

scientific article published on 30 June 2011

Safe genetic modification of cardiac stem cells using a site-specific integration technique

scientific article

Screening drug-induced arrhythmia [corrected] using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays

scientific article

Site-specific recombinase strategy to create induced pluripotent stem cells efficiently with plasmid DNA.

scientific article published on November 2011

Suppression of Nestin reveals a critical role for p38-EGFR pathway in neural progenitor cell proliferation.

scientific article

Survivin Improves Reprogramming Efficiency of Human Neural Progenitors by Single Molecule OCT4.

scientific article

The Complement C3a-C3aR Axis Promotes Development of Thoracic Aortic Dissection via Regulation of MMP2 Expression.

scientific article published on 24 January 2018

The hemostatic disturbance in patients with acute aortic dissection: A prospective observational study

scientific article published on September 2016

β-Aminopropionitrile monofumarate induces thoracic aortic dissection in C57BL/6 mice.

scientific article published on 22 June 2016