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List of works by Frank Dudbridge

9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium

scientific article published on 02 August 2012

A HaemAtlas: characterizing gene expression in differentiated human blood cells

scientific article

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

A flexible and parallelizable approach to genome-wide polygenic risk scores

scientific article published on 22 July 2019

A flexible model for association analysis in sibships with missing genotype data

scientific article

A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways.

scientific article published on 8 May 2009

A non-synonymous SNP within membrane metalloendopeptidase-like 1 (MMEL1) is associated with multiple sclerosis

scientific article

A note on permutation tests in multistage association scans.

scientific article published on June 2006

A rare variant of the TYK2 gene is confirmed to be associated with multiple sclerosis

scientific article published on 4 November 2009

Accuracy of Gene Scores when Pruning Markers by Linkage Disequilibrium

scientific article published on 01 January 2015

Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis

scientific article published in December 2016

Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation

article

An investigation of the neurotrophic factor genes GDNF, NGF, and NT3 in susceptibility to ADHD.

scientific article published on April 2007

Application of the optimal discovery procedure to genetic case-control studies: comparison with p values and asymptotic Bayes factors.

scientific article

Are Your Covariates Under Control? How Normalization Can Re-introduce Covariate Effects

Are genetic risk factors for psychosis also associated with dimension-specific psychotic experiences in adolescence? ⬇️

scientific article

Are your covariates under control? How normalization can re-introduce covariate effects

scientific article published on 30 April 2018

Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs

scientific article published on 4 November 2011

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

scientific article

Association between protective and deleterious HLA alleles with multiple sclerosis in Central East Sardinia

scientific article

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events

scientific article published on 21 March 2019

Association of common genetic variants with lipid traits in the Indian population

scientific article

Association of the paternally transmitted copy of common Valine allele of the Val66Met polymorphism of the brain-derived neurotrophic factor (BDNF) gene with susceptibility to ADHD.

scientific article published in October 2005

Association study of 25 type 2 diabetes related Loci with measures of obesity in Indian sib pairs

scientific article

Associations of FTO and MC4R Variants with Obesity Traits in Indians and the Role of Rural/Urban Environment as a Possible Effect Modifier

scientific article published on 17 May 2011

Author Correction: Genome-wide association study of self-reported walking pace suggests beneficial effects of brisk walking on health and survival

scientific article published on 10 November 2020

Candidate gene-environment interactions in breast cancer

scientific article

Candidate genes for obesity-susceptibility show enriched association within a large genome-wide association study for BMI.

scientific article

Capture Hi-C identifies putative target genes at 33 breast cancer risk loci.

scientific article published on 12 March 2018

Causal Analyses, Statistical Efficiency And Phenotypic Precision Through Recall-By-Genotype Study Design

Causal Associations of Adiposity and Body Fat Distribution with Coronary Heart Disease, Stroke Subtypes and Type 2 Diabetes: A Mendelian Randomization Analysis

scientific article

Causal inference methods for intergenerational research using observational data.

scientific article published in 2023

Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts

scientific article published on 26 March 2020

Clonal architecture in mesothelioma is prognostic and shapes the tumour microenvironment

scientific article published on 19 March 2021

Combining information on multiple instrumental variables in Mendelian randomization: comparison of allele score and summarized data methods

scientific article

Commentary: Tobacco consumption and body weight: Mendelian randomization across a range of exposure

scientific article published on 26 March 2015

Common sequence variation in FLNB regulates bone structure in women in the general population and FLNB mRNA expression in osteoblasts in vitro

scientific article published in December 2009

Common variants on chromosome 6p22.1 are associated with schizophrenia

scientific article

Comparison of methods for competitive tests of pathway analysis

scientific article

Comparison of multimarker logistic regression models, with application to a genomewide scan of schizophrenia.

scientific article

Conditional testing of multiple variants associated with bone mineral density in the FLNB gene region suggests that they represent a single association signal

scientific article

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

scientific article

Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications

scientific article

Copy number variation of the APC gene is associated with regulation of bone mineral density

scientific article published on 02 August 2012

Criteria for evaluating risk prediction of multiple outcomes

scientific article published on 29 June 2020

Cytochrome P450 Allele CYP3A7*1C Associates with Adverse Outcomes in Chronic Lymphocytic Leukemia, Breast, and Lung Cancer

scientific article published on 10 March 2016

Definition of novel GP6 polymorphisms and major difference in haplotype frequencies between populations by a combination of in-depth exon resequencing and genotyping with tag single nucleotide polymorphisms

scientific article published on June 2006

Detecting multiple associations in genome-wide studies

scientific article

Early and current socio-economic position and cardiometabolic risk factors in the Indian Migration Study

scientific article published on 18 April 2012

Epigenome-Wide Association Study of Thyroid Function Traits Identifies Novel Associations of fT3 With <i>KLF9</i> and <i>DOT1L</i>

scientific article published in 2021

Erratum: Whole-genome sequence-based analysis of thyroid function

scientific article published on 20 May 2015

Estimating causal effects of genetic risk variants for breast cancer using marker data from bilateral and familial cases

scientific article

Estimation of a significance threshold for epigenome-wide association studies

scientific article

Estimation of significance thresholds for genomewide association scans

scientific article

Evaluation of Nyholt's procedure for multiple testing correction

scientific article published on 23 August 2005

Evaluation of seven common lipid associated loci in a large Indian sib pair study

scientific article published on 14 November 2012

Expression Quantitative Trait Locus Study of Bone Mineral Density GWAS Variants in Human Osteoclasts

scientific article published on 23 February 2018

Family-Based Association Studies ⬇️

scientific article published on 01 January 2011

Fast and robust association tests for untyped SNPs in case-control studies

scientific article published on 30 July 2010

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.

scientific article published on 4 February 2015

Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins

scientific article

Further genetic evidence suggesting a role for the RhoGTPase-RhoGEF pathway in osteoporosis

scientific article

Gene-environment dependence creates spurious gene-environment interaction

scientific article

Genes of the class II and class III major histocompatibility complex are associated with typhoid fever in Vietnam

scientific article published on 21 December 2000

Genes related to sex steroids, neural growth, and social-emotional behavior are associated with autistic traits, empathy, and Asperger syndrome

scientific article

Genetic association studies in pre-eclampsia: systematic meta-analyses and field synopsis

scientific article

Genetic determinants of major blood lipids in Pakistanis compared with Europeans

scientific article published on 22 June 2010

Genetic prediction of quantitative lipid traits: comparing shrinkage models to gene scores

scientific article published on 23 November 2013

Genetic predisposition to hypertension is associated with preeclampsia in European and Central Asian women

scientific article published on 25 November 2020

Genetic regulatory mechanisms in human osteoclasts suggest a role for the STMP1 and DCSTAMP genes in Paget's disease of bone

scientific article published in Scientific Reports

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

scientific article

Genetic variants at chromosomes 2q35, 5p12, 6q25.1, 10q26.13, and 16q12.1 influence the risk of breast cancer in men

scientific article

Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study

scientific article

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

scientific article published in October 2013

Genome-wide association study meta-analysis for quantitative ultrasound parameters of bone identifies five novel loci for broadband ultrasound attenuation

scientific article published on 4 May 2017

Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms ⬇️

scientific article

Genome-wide association study of self-reported walking pace suggests beneficial effects of brisk walking on health and survival

scientific article published on 30 October 2020

Genome-wide association study using family-based cohorts identifies the WLS and CCDC170/ESR1 loci as associated with bone mineral density

scientific article

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

article

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

scientific article published on 8 August 2017

HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials

scientific article published on 24 September 2014

Haplotype tagging for the identification of common disease genes

article

Heritability of Individual Psychotic Experiences Captured by Common Genetic Variants in a Community Sample of Adolescents ⬇️

scientific article

How many cases of disease in a pedigree imply familial disease?

scientific article published on 23 October 2017

Identification of a role for the ARHGEF3 gene in postmenopausal osteoporosis

scientific article published on 22 May 2008

Impact of Selection Bias on Estimation of Subsequent Event Risk

scientific article published in October 2017

Improving the power to detect differentially expressed genes in comparative microarray experiments by including information from self-self hybridizations

scientific article published on 24 March 2007

Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia

scientific article

Interpreting Association Signals

Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data

scientific article published on 31 March 2008

Linkage analysis of Genetic Analysis Workshop 12 simulated data based on affected individuals only.

scientific article

Linkage and association mapping of the LRP5 locus on chromosome 11q13 in type 1 diabetes

scientific article published on 17 April 2003

Linkage and potential association of obesity-related phenotypes with two genes on chromosome 12q24 in a female dizygous twin cohort

scientific article published in March 2006

List of Contributors

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

scientific article published on 8 April 2022

Mapping the platelet profile for functional genomic studies and demonstration of the effect size of the GP6 locus

scientific article published in August 2007

Marginal role for 53 common genetic variants in cardiovascular disease prediction

scientific article published on 30 June 2016

Maximizing association statistics over genetic models

article

Mendelian Randomisation study of the influence of eGFR on coronary heart disease

scientific article published on 24 June 2016

Mendelian randomization of blood lipids for coronary heart disease

scientific article

Mendelian randomization with Egger pleiotropy correction and weakly informative Bayesian priors

scientific article

New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

scientific article

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

scientific article published on 25 February 2019

New genetic signals for lung function highlight pathways and pleiotropy, and chronic obstructive pulmonary disease associations across multiple ancestries

scholarly article published 12 June 2018

Pelican: pedigree editor for linkage computer analysis.

scientific article published in April 2004

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

scientific article published on 15 January 2016

Polygenic Epidemiology

scientific article

Polygenic Mendelian Randomization

scientific article published on 30 March 2020

Polymorphism in HSD17B6 is associated with key features of polycystic ovary syndrome.

scientific article

Polymorphism in postinsulin receptor signaling pathway is not associated with polycystic ovary syndrome.

scientific article

Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium

scientific article (publication date: 2013)

Power and predictive accuracy of polygenic risk scores.

scientific article

Prediction of breast cancer risk based on profiling with common genetic variants

scientific article published on 8 April 2015

Predictive accuracy of combined genetic and environmental risk scores

scientific article published on 26 November 2017

Rank truncated product of P-values, with application to genomewide association scans

scientific article published in December 2003

Re: Is the Risk Difference Really a More Heterogeneous Measure?

scientific article published on 01 May 2016

Re: “Multivariable Mendelian Randomization: The Use of Pleiotropic Genetic Variants to Estimate Causal Effects”

scientific article published on 5 February 2015

Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor

scientific article published on 18 March 2009

Research review: Polygenic methods and their application to psychiatric traits

scientific article

Retrospective analysis of the quality of reports by author-suggested and non-author-suggested reviewers in journals operating on open or single-blind peer review models

scientific article published on 29 September 2015

Sixty-five common genetic variants and prediction of type 2 diabetes

scientific article published on 4 December 2014

Subsequent Event Risk in Individuals With Established Coronary Heart Disease

scientific article published on 21 March 2019

Testing for non-linear causal effects using a binary genotype in a Mendelian randomization study: application to alcohol and cardiovascular traits

scientific article

The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis

scientific article published on 14 March 2012

Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function

scientific article

Transmission of human herpesvirus type 8 infection within families in american indigenous populations from the Brazilian Amazon

scientific article published on 3 April 2012

Two novel pathway analysis methods based on a hierarchical model.

scientific article published on 11 October 2013

Typhoid fever and genetic polymorphisms at the natural resistance-associated macrophage protein 1.

scientific article published on March 2001

Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C.

scientific article

Unbiased estimation of odds ratios: combining genomewide association scans with replication studies.

scientific article published on July 2009

Utilising family-based designs for detecting rare variant disease associations

scientific article

Variants in the fetal genome near FLT1 are associated with risk of preeclampsia

scientific article published on 19 June 2017

What role for genetics in the prediction of multiple sclerosis?

scientific article

Whole-genome sequence-based analysis of thyroid function.

scientific article

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