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List of works by Lyle Armstrong

A Novel Role for miR-1305 in Regulation of Pluripotency-Differentiation Balance, Cell Cycle, and Apoptosis in Human Pluripotent Stem Cells

scientific article published on 24 June 2016

A critical role for p38MAPK signalling pathway during reprogramming of human fibroblasts to iPSCs.

scientific article

A human iPSC model of Ligase IV deficiency reveals an important role for NHEJ-mediated-DSB repair in the survival and genomic stability of induced pluripotent stem cells and emerging haematopoietic progenitors.

scientific article

A novel model of urinary tract differentiation, tissue regeneration, and disease: reprogramming human prostate and bladder cells into induced pluripotent stem cells

scientific article published on 06 April 2013

A putative role for the immunoproteasome in the maintenance of pluripotency in human embryonic stem cells.

scientific article published in July 2012

Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells.

scientific article

Aging of Stem and Progenitor Cells: Mechanisms, Impact on Therapeutic Potential, and Rejuvenation

scientific article published on 09 June 2015

An Induced Pluripotent Stem Cell Patient Specific Model of Complement Factor H (Y402H) Polymorphism Displays Characteristic Features of Age-Related Macular Degeneration and Indicates a Beneficial Role for UV Light Exposure. ⬇️

scientific article published on 15 September 2017

An autogeneic feeder cell system that efficiently supports growth of undifferentiated human embryonic stem cells.

scientific article published on March 2005

An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells

scientific article

Brief Report: Inhibition of miR-145 Enhances Reprogramming of Human Dermal Fibroblasts to Induced Pluripotent Stem Cells.

scientific article

Brief report: human pluripotent stem cell models of fanconi anemia deficiency reveal an important role for fanconi anemia proteins in cellular reprogramming and survival of hematopoietic progenitors.

scientific article published in May 2013

Characterisation of Wnt gene expression during the differentiation of murine embryonic stem cells in vitro: role of Wnt3 in enhancing haematopoietic differentiation.

scientific article

Complement modulation reverses pathology in Y402H-retinal pigment epithelium cell model of age-related macular degeneration by restoring lysosomal function

scientific article published on 20 August 2020

Concise Review: Cardiac Disease Modeling Using Induced Pluripotent Stem Cells.

scientific article published on 28 May 2015

Concise Review: Getting to the Core of Inherited Bone Marrow Failures.

scientific article

Concise review: the epigenetic contribution to stem cell ageing: can we rejuvenate our older cells?

scientific article published on September 2014

Derivation and functional analysis of patient-specific induced pluripotent stem cells as an in vitro model of chronic granulomatous disease

scientific article published on April 2012

Differences in the Activity of Endogenous Bone Morphogenetic Protein Signaling Impact on the Ability of Induced Pluripotent Stem Cells to Differentiate to Corneal Epithelial-Like Cells.

scientific article published on 11 December 2017

Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa ⬇️

scientific article published in Nature Communications

Downregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages

scientific article

Downregulation of multiple stress defense mechanisms during differentiation of human embryonic stem cells

scientific article published on 29 November 2007

Editorial: Our top 10 developments in stem cell biology over the last 30 years

scientific article published in January 2012

Efficient hematopoietic differentiation of human embryonic stem cells on stromal cells derived from hematopoietic niches.

scientific article

Engraftment's Holy Grail: is one signal enough?

scientific article published in November 2014

Epigenetic control of embryonic stem cell differentiation.

scientific article published on March 2012

Epigenetic landscaping during hESC differentiation to neural cells.

scientific article

Epigenetic marking prepares the human HOXA cluster for activation during differentiation of pluripotent cells.

scientific article

Epigenetic modification is central to genome reprogramming in somatic cell nuclear transfer.

scientific article

Ethical and Safety Issues of Stem Cell-Based Therapy.

scientific article published in January 2018

Expression of GFP under the control of the RNA helicase VASA permits fluorescence-activated cell sorting isolation of human primordial germ cells.

scientific article

Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells

scholarly article by Minjin Jeong et al published 11 September 2018 in Cell Death and Disease

Generation of Human Induced Pluripotent Stem Cells Using RNA-Based Sendai Virus System and Pluripotency Validation of the Resulting Cell Population

scientific article published on 20 February 2015

Hepatic differentiation of human iPSCs in different 3D models: A comparative study.

scientific article published on 16 October 2017

Human embryonic stem cells: biology and clinical implications.

scientific article

Human iPSC differentiation to retinal organoids in response to IGF1 and BMP4 activation is line- and method-dependent

scientific article published on 30 December 2019

Human iPSC disease modelling reveals functional and structural defects in retinal pigment epithelial cells harbouring the m.3243A > G mitochondrial DNA mutation.

scientific article published on 26 September 2017

Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells

scientific article published on 01 April 2010

Human-Induced Pluripotent Stem Cells Generate Light Responsive Retinal Organoids with Variable and Nutrient-Dependent Efficiency

scientific article published on 13 August 2018

Induced pluripotent stem cell modelling of HLHS underlines the contribution of dysfunctional NOTCH signalling to impaired cardiogenesis

scientific article published on 17 May 2017

Induced pluripotent stem cells : it looks simple but can looks deceive?

scientific article published on 01 May 2010

Intercalating TOP2 Poisons Attenuate Topoisomerase Action at Higher Concentrations

scientific article published on 09 August 2019

Isolation of primordial germ cells from differentiating human embryonic stem cells

scientific article published on 18 September 2008

JNK/SAPK Signaling Is Essential for Efficient Reprogramming of Human Fibroblasts to Induced Pluripotent Stem Cells

scientific article

Law should recognize value of interspecies embryos

scientific article published on 01 February 2008

Multiplex High-Throughput Targeted Proteomic Assay To Identify Induced Pluripotent Stem Cells

scientific article published on 6 February 2017

Nanog regulates primordial germ cell migration through Cxcr4b.

scientific article published in September 2010

Non-invasive imaging of stem cells by scanning ion conductance microscopy: future perspective

scientific article

Overexpression of telomerase confers growth advantage, stress resistance, and enhanced differentiation of ESCs toward the hematopoietic lineage.

scientific article

Phenotypic characterization of murine primitive hematopoietic progenitor cells isolated on basis of aldehyde dehydrogenase activity.

scientific article published in January 2004

Platform to study intracellular polystyrene nanoplastic pollution and clinical outcomes

scientific article published on 02 July 2020

Pluripotent Stem Cell-Derived Hematopoietic Progenitors Are Unable to Downregulate Key Epithelial-Mesenchymal Transition-Associated miRNAs.

scientific article

Potential for pharmacological manipulation of human embryonic stem cells.

scientific article published on May 2013

Primordial Germ Cells: Current Knowledge and Perspectives

scientific article

Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience

scientific article

Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study

article

Response to letter by Hallam et al.

scientific article

Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage

scientific article

Silencing of the expression of pluripotent driven-reporter genes stably transfected into human pluripotent cells

scientific article published on 01 July 2008

The future of human nuclear transfer?

scientific article published on January 2006

The mitochondrial protein CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages.

scientific article published on 17 October 2016

The role of PI3K/AKT, MAPK/ERK and NFkappabeta signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis.

scientific article

Towards optimisation of induced pluripotent cell culture: Extracellular acidification results in growth arrest of iPSC prior to nutrient exhaustion.

scientific article published on 15 August 2017

iPSC modeling of severe aplastic anemia reveals impaired differentiation and telomere shortening in blood progenitors

scientific article published on 26 January 2018

mTert expression correlates with telomerase activity during the differentiation of murine embryonic stem cells.

scientific article published in October 2000

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