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List of works by Sebastian Guettler

A myristoyl/phosphotyrosine switch regulates c-Abl

scientific article published on March 2003

AXIN Shapes Tankyrase ARChitecture

scientific article published in October 2016

ESTs from the basidiomycete Schizophyllum commune grown on nitrogen-replete and nitrogen-limited media.

scientific article

Fragment-based screening identifies molecules targeting the substrate-binding ankyrin repeat domains of tankyrase

scientific article published on 13 December 2019

Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance.

scientific article published on 10 May 2018

MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway

scientific article

Molecular basis for G-actin binding to RPEL motifs from the serum response factor coactivator MAL

scientific article

Mutant actins that stabilise F-actin use distinct mechanisms to activate the SRF coactivator MAL.

scientific article published on 23 September 2004

Nedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function

scientific article

Nuclear actin regulates dynamic subcellular localization and activity of the SRF cofactor MAL.

scientific article

RPEL motifs link the serum response factor cofactor MAL but not myocardin to Rho signaling via actin binding

scientific article published on 19 November 2007

Reconstitution of the destruction complex defines roles of AXIN polymers and APC in β-catenin capture, phosphorylation, and ubiquitylation

scientific article published on 04 August 2021

Regulation of Protein Interactions by Mps One Binder (MOB1) Phosphorylation

scientific article

Regulation of Wnt/β-catenin signalling by tankyrase-dependent poly(ADP-ribosyl)ation and scaffolding.

scientific article published on 14 September 2017

Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment

scholarly article by Shawn Xiong published in August 2018

Structural basis and sequence rules for substrate recognition by Tankyrase explain the basis for cherubism disease

scientific article

Structure of a pentavalent G-actin*MRTF-A complex reveals how G-actin controls nucleocytoplasmic shuttling of a transcriptional coactivator

scientific article

Tankyrase Requires SAM Domain-Dependent Polymerization to Support Wnt-β-Catenin Signaling

scientific article published on August 2016

The genomic landscape of oesophagogastric junctional adenocarcinoma

scientific article