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List of works by Jayne C. Hope

1,25-dihydroxyvitamin D3 and development of tuberculosis in cattle

scientific article published on November 2003

ADGRE1 (EMR1, F4/80) Is a Rapidly-Evolving Gene Expressed in Mammalian Monocyte-Macrophages

article

Alpha/beta and gamma interferons are induced by infection with noncytopathic bovine viral diarrhea virus in vivo.

scientific article

An outbreak of tuberculosis due to Mycobacterium bovis infection in a pack of English Foxhounds (2016-2017)

scientific article published on 30 July 2018

Anaplasma marginale major surface protein 2 CD4+-T-cell epitopes are evenly distributed in conserved and hypervariable regions (HVR), whereas linear B-cell epitopes are predominantly located in the HVR.

scientific article

Anatomical distribution of respiratory tract leukocyte cell subsets in neonatal calves

scientific article published on 02 July 2020

Animal African Trypanosomiasis: Time to Increase Focus on Clinically Relevant Parasite and Host Species.

scientific article published on 7 May 2016

Antigen-induced unresponsiveness in contact sensitivity: association of depressed T lymphocyte proliferative responses with decreased interleukin 6 secretion.

scientific article

Antigen-specific peripheral immune responses are unaltered during normal pregnancy in sheep.

scientific article

BCG vaccination of neonatal calves: potential roles for innate immune cells in the induction of protective immunity.

scientific article published on 14 December 2011

Bovine NK cells can produce gamma interferon in response to the secreted mycobacterial proteins ESAT-6 and MPP14 but not in response to MPB70.

scientific article

Bovine TB and the development of new vaccines

scientific article published on 30 August 2007

Bovine cryptosporidiosis: impact, host-parasite interaction and control strategies.

scientific article published on 11 August 2017

Bovine γδ T cells are a major regulatory T cell subset.

scientific article published on 2 June 2014

Bovine γδ T cells: cells with multiple functions and important roles in immunity

scientific article published on 13 March 2011

Breadth of the CD4+ T cell response to Anaplasma marginale VirB9-1, VirB9-2 and VirB10 and MHC class II DR and DQ restriction elements

scientific article

CD205 antigen targeting combined with dendritic cell recruitment factors and antigen-linked CD40L activation primes and expands significant antigen-specific antibody and CD4(+) T cell responses following DNA vaccination of outbred animals.

scientific article

Caveolae and caveolin in immune cells: distribution and functions.

scientific article

Characterisation of a novel vaccine delivery system for livestock.

scientific article

Characterisation of antibodies to bovine Toll-like receptor (TLR)-2 and cross-reactivity with ovine TLR2.

scientific article

Characterization of a phenotypically unique population of CD13+ dendritic cells resident in the spleen.

scientific article

Characterization of the bovine innate immune response to intramammary infection with Klebsiella pneumoniae.

scientific article

Consequence of prior exposure to environmental mycobacteria on BCG vaccination and diagnosis of tuberculosis infection.

scientific article

CpG ODN 2006 and IL-12 are comparable for priming Th1 lymphocyte and IgG responses in cattle immunized with a rickettsial outer membrane protein in alum.

scientific article published in July 2003

Cytokine and Chemokine Concentrations as Biomarkers of Feline Mycobacteriosis

scientific article published in Scientific Reports

Cytotoxicity and cytokine production by bovine alveolar macrophages challenged with wild type and leukotoxin-deficient Mannheimia haemolytica.

scientific article

DEC-205 expression on migrating dendritic cells in afferent lymph

scientific article published in March 2004

DNA vaccine construct incorporating intercellular trafficking and intracellular targeting motifs effectively primes and induces memory B- and T-cell responses in outbred animals.

scientific article published on 10 January 2007

DNA-encoded fetal liver tyrosine kinase 3 ligand and granulocyte macrophage-colony-stimulating factor increase dendritic cell recruitment to the inoculation site and enhance antigen-specific CD4+ T cell responses induced by DNA vaccination of outbre

scientific article published on October 2002

Dendritic cell subtypes from lymph nodes and blood show contrasted gene expression programs upon Bluetongue virus infection

scientific article published on 19 June 2013

Dendritic cells in cattle: phenotype and function.

scientific article

Dendritic cells, implications on function from studies of the afferent lymph veiled cell.

scientific article

Development of a simple, sensitive, rapid test which discriminates BCG-vaccinated from Mycobacterium bovis-infected cattle.

scientific article published on 8 August 2008

Development of an ELISA for bovine IL-10.

scientific article

Development of detection methods for ruminant interleukin (IL)-12.

scientific article

Development of in vitro enteroids derived from bovine small intestinal crypts.

scientific article published on 3 July 2018

Diagnosis of feline mycobacteriosis: Feline mycobacteriosis.

scientific article

Dietary-induced negative energy balance has minimal effects on innate immunity during a Streptococcus uberis mastitis challenge in dairy cows during midlactation.

scientific article published in September 2009

Differential distribution of WC1(+) gammadelta TCR(+) T lymphocyte subsets within lymphoid tissues of the head and respiratory tract and effects of intranasal M. bovis BCG vaccination.

scientific article

Differential effects of viral vectors on migratory afferent lymph dendritic cells in vitro predict enhanced immunogenicity in vivo.

scientific article

Differential production of cytokines, reactive oxygen and nitrogen by bovine macrophages and dendritic cells stimulated with Toll-like receptor agonists.

scientific article published in January 2004

Differential recruitment and activation of natural killer cell sub-populations by Mycobacterium bovis-infected dendritic cells.

scientific article

Direct manipulation of T lymphocytes by proteins of gastrointestinal bacterial pathogens

scientific article published on 16 January 2018

Duration of immunity against Mycobacterium bovis following neonatal vaccination with bacillus Calmette-Guérin Danish: significant protection against infection at 12, but not 24, months.

scientific article

Enhanced secretion of interferon-gamma by bovine gammadelta T cells induced by coculture with Mycobacterium bovis-infected dendritic cells: evidence for reciprocal activating signals

scientific article published on 22 July 2008

Enhancing the toolbox to study IL-17A in cattle and sheep.

scientific article published on 08 April 2017

Escherichia coli and Staphylococcus aureus elicit differential innate immune responses following intramammary infection.

scientific article

Establishment of bovine 3D enteroid-derived 2D monolayers

scientific article published on 02 March 2022

Evaluation of cellular and humoral systemic immune response against Giardia duodenalis infection in cattle

scientific article published on 20 March 2014

Existence of CD8α-like dendritic cells with a conserved functional specialization and a common molecular signature in distant mammalian species

scientific article

Exposure to Mycobacterium avium induces low-level protection from Mycobacterium bovis infection but compromises diagnosis of disease in cattle.

scientific article

Exposure to Mycobacterium avium primes the immune system of calves for vaccination with Mycobacterium bovis BCG.

scientific article

Feline tuberculosis caused by Mycobacterium bovis infection of domestic UK cats associated with feeding a commercial raw food diet

scientific article published on 22 October 2020

Flow cytometric detection of gamma interferon can effectively discriminate Mycobacterium bovis BCG-vaccinated cattle from M. bovis-infected cattle.

scientific article

Foot-and-mouth disease virus exhibits an altered tropism in the presence of specific immunoglobulins, enabling productive infection and killing of dendritic cells.

scientific article

Frequency and phenotype of natural killer cells and natural killer cell subsets in bovine lymphoid compartments and blood.

scientific article published on 7 January 2017

Giardia duodenalis stimulates partial maturation of bovine dendritic cells associated with altered cytokine secretion and induction of T-cell proliferation

scientific article published on April 2014

Humoral and cellular immune responses to Fasciola gigantica experimental infection in buffaloes.

scientific article published on 6 September 2005

Identification of surrogates and correlates of protection in protective immunity against Mycobacterium bovis infection induced in neonatal calves by vaccination with M. bovis BCG Pasteur and M. bovis BCG Danish

scientific article

Immunity, safety and protection of an Adenovirus 5 prime--Modified Vaccinia virus Ankara boost subunit vaccine against Mycobacterium avium subspecies paratuberculosis infection in calves

scientific article

Inhibition of Antigen-Specific and Nonspecific Stimulation of Bovine T and B Cells by Lymphostatin from Attaching and Effacing Escherichia coli

scientific article published on 05 December 2016

Innate immune response to intramammary infection with Serratia marcescens and Streptococcus uberis

scientific article

Interaction of antigen presenting cells with mycobacteria.

scientific article published on August 2004

Interactions between natural killer cells and dendritic cells favour T helper1-type responses to BCG in calves.

scientific article published on 17 August 2016

Interleukin-6 production by draining lymph node cells following primary contact sensitisation of mice: relationship to the proliferative response.

scientific article published in January 1994

Isolation and purification of afferent lymph dendritic cells that drain the skin of cattle

scientific article published in January 2006

Masking of two in vitro immunological assays for Mycobacterium bovis (BCG) in calves acutely infected with non‐qctopathic bovine viral diarrhoea virus ⬇️

scientific article published on October 20, 2001

Maturation of bovine dendritic cells by lipopeptides

scientific article published in September 2003

Migratory sub-populations of afferent lymphatic dendritic cells differ in their interactions with Mycobacterium bovis Bacille Calmette Guerin.

scientific article

Modified vaccinia virus Ankara-based vaccine vectors induce apoptosis in dendritic cells draining from the skin via both the extrinsic and intrinsic caspase pathways, preventing efficient antigen presentation.

scientific article

Modulation of the bovine delayed-type hypersensitivity responses to defined mycobacterial antigens by a synthetic bacterial lipopeptide

scientific article

Mycobacterium bovis infection in working foxhounds

scientific article published on 01 September 2018

Mycobacterium bovis shedding patterns from experimentally infected calves and the effect of concurrent infection with bovine viral diarrhoea virus

scientific article published on June 2007

Mycobacterium paratuberculosis heat shock protein 70 as a tool in control of paratuberculosis.

scientific article

NK-like CD8(+) cells in immunologically naïve neonatal calves that respond to dendritic cells infected with Mycobacterium bovis BCG.

scientific article

NKp46 defines a subset of bovine leukocytes with natural killer cell characteristics.

scientific article published on March 2004

NKp46+ CD3+ cells: a novel nonconventional T cell subset in cattle exhibiting both NK cell and T cell features

scientific article published on 17 March 2014

Natural Killer Cells in Afferent Lymph Express an Activated Phenotype and Readily Produce IFN-γ.

scientific article published on 22 November 2013

Natural killer cell number and phenotype in bovine peripheral blood is influenced by age.

scientific article published on 18 May 2009

Nature and consequences of interactions between Salmonella enterica serovar Dublin and host cells in cattle

scientific article published on 27 November 2019

Ocular Tuberculosis: More than 'Of Mice and Men'

scientific article published on 18 September 2020

Phenotypic and functional analysis of monocyte populations in cattle peripheral blood identifies a subset with high endocytic and allogeneic T-cell stimulatory capacity.

scientific article

Plasmacytoid dendritic cells migrate in afferent skin lymph

scientific article published in May 2008

Production and characterization of two monoclonal antibodies to bovine tumour necrosis factor alpha (TNF-alpha) and their cross-reactivity with ovine TNF-alpha.

scientific article

Quantifying Mycobacterium avium subspecies paratuberculosis infection of bovine monocyte derived macrophages by confocal microscopy

scientific article published on 19 November 2019

Quantifying the Survival of Multiple Salmonella enterica Serovars in vivo using Massively-parallel Whole Genome Sequencing to Predict Zoonotic Risk

scientific article

Rapid and long-term disappearance of CD4+ T lymphocyte responses specific for Anaplasma marginale major surface protein-2 (MSP2) in MSP2 vaccinates following challenge with live A. marginale.

scientific article

Relative quantitative kinetics of interferon-gamma and interleukin-10 mRNA and protein production by activated ovine peripheral blood mononuclear cells.

scientific article

Retrospective application of transposon-directed insertion-site sequencing to investigate niche-specific virulence of Salmonella Typhimurium in cattle

scientific article published on 08 January 2019

Single-cell analysis divides bovine monocyte-derived dendritic cells into subsets expressing either high or low levels of inducible nitric oxide synthase.

scientific article published on 5 September 2006

Stem cell-derived porcine macrophages as a new platform for studying host-pathogen interactions

Subset-Specific Expression of Toll-Like Receptors by Bovine Afferent Lymph Dendritic Cells.

scientific article published on 03 April 2017

Th1-Th2 polarisation and autophagy in the control of intracellular mycobacteria by macrophages.

scientific article published on 17 October 2008

The UK Veterinary Immunological Toolbox Website: promoting vaccine research by facilitating communication and removing reagent barriers

scientific article published on 16 June 2020

The Veterinary Immunological Toolbox: Past, Present, and Future

scientific article published on 28 July 2020

The bovine innate immune response during experimentally-induced Pseudomonas aeruginosa mastitis.

scientific article

The double-stranded RNA bluetongue virus induces type I interferon in plasmacytoid dendritic cells via a MYD88-dependent TLR7/8-independent signaling pathway.

scientific article

The effect of repeated tuberculin skin testing of cattle on immune responses and disease following experimental infection with Mycobacterium bovis.

scientific article

The effect of tuberculin testing on the development of cell-mediated immune responses during Mycobacterium bovis infection.

scientific article published on 14 August 2006

The role of dendritic cells in shaping the immune response.

scientific article

Transduction of skin-migrating dendritic cells by human adenovirus 5 occurs via an actin-dependent phagocytic pathway

scientific article published on 15 August 2016

Tuberculosis due to Mycobacterium bovis in pet cats associated with feeding a commercial raw food diet

scientific article published on 13 May 2019

Tuberculosis immunity: opportunities from studies with cattle

scientific article

Tumor necrosis factor blockers influence macrophage responses to Mycobacterium tuberculosis

scientific article published in December 2008

Vaccines for bovine tuberculosis: current views and future prospects.

scientific article

Workshop cluster 1+ gammadelta T-cell receptor T cells from calves express high levels of interferon-gamma in response to stimulation with interleukin-12 and -18.

scientific article published on 11 October 2006

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