List of works - Brian McStay

A localized nucleolar DNA damage response facilitates recruitment of the homology-directed repair machinery independent of cell cycle stage.

scientific article published on 27 May 2015

A termination site for Xenopus RNA polymerase I also acts as an element of an adjacent promoter

scientific article published on 01 December 1986

Association of the nucleolar transcription factor UBF with the transcriptionally inactive rRNA genes of pronuclei and early Xenopus embryos ⬇️

scientific article published on September 1, 1997

Construction of synthetic nucleoli and what it tells us about propagation of sub-nuclear domains through cell division.

scientific article

Construction of synthetic nucleoli in human cells reveals how a major functional nuclear domain is formed and propagated through cell division.

scientific article published on 21 January 2014

DNA repair: location, location, location

scientific article published in July 2015

Dimerization and HMG box domains 1-3 present in Xenopus UBF are sufficient for its role in transcriptional enhancement.

scientific article published on August 1998

HMG box 4 is the principal determinant of species specificity in the RNA polymerase I transcription factor UBF.

scientific article published on November 1995

Human NORs, comprising rDNA arrays and functionally conserved distal elements, are located within dynamic chromosomal regions

scientific article published on 14 November 2019

Human acrocentric chromosomes with transcriptionally silent nucleolar organizer regions associate with nucleoli

scientific article (publication date: June 2001)

Identification and cDNA cloning of a Xenopus nucleolar phosphoprotein, xNopp180, that is the homolog of the rat nucleolar protein Nopp140 ⬇️

scientific article published on October 1, 1995

Integrating the genomic architecture of human nucleolar organizer regions with the biophysical properties of nucleoli

scientific article published on 13 May 2017

Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis

scientific article

Linker scanner mutagenesis of the Xenopus laevis ribosomal gene promoter

scientific article

NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing

scientific article

NORs on human acrocentric chromosome p-arms are active by default and can associate with nucleoli independently of rDNA

scientific article published on 24 April 2020

Nucleolar organizer regions: genomic 'dark matter' requiring illumination

scientific article

Nucleolar protein upstream binding factor is sequestered into adenovirus DNA replication centres during infection without affecting RNA polymerase I location or ablating rRNA synthesis

scientific article published in June 2006

Nucleolar reorganization in response to rDNA damage

scientific article

Oddpols united: new insights into transcription by RNA polymerases I and III.

scientific article

Processing and termination of RNA polymerase I transcripts

scientific article published on 01 March 1987

Recruitment of factors linking transcription and processing of pre-rRNA to NOR chromatin is UBF-dependent and occurs independent of transcription in human cells

scientific journal article

Replication timing of pseudo-NORs.

scientific article published on 3 December 2010

Ribosome biogenesis: Achilles heel of cancer?

scientific article

Structure-function analysis of Hmo1 unveils an ancestral organization of HMG-Box factors involved in ribosomal DNA transcription from yeast to human.

scientific article published on 09 September 2013

The Relationship Between Human Nucleolar Organizer Regions and Nucleoli, Probed by 3D-ImmunoFISH.

scientific article

The Xenopus RNA polymerase I transcription factor, UBF, has a role in transcriptional enhancement distinct from that at the promoter.

scientific article

The Xenopus ribosomal gene enhancers bind an essential polymerase I transcription factor, xUBF

scientific article published on 01 November 1989

The shared genomic architecture of human nucleolar organizer regions.

scientific article

UBF binding in vivo is not restricted to regulatory sequences within the vertebrate ribosomal DNA repeat

scientific article

UBF-binding site arrays form pseudo-NORs and sequester the RNA polymerase I transcription machinery.

scientific article

Upstream binding factor stabilizes Rib 1, the TATA-binding-protein-containing Xenopus laevis RNA polymerase I transcription factor, by multiple protein interactions in a DNA-independent manner.

scientific article published on October 1996

xUBF, an RNA polymerase I transcription factor, binds crossover DNA with low sequence specificity

scientific article published on May 1994

List of works by Brian McStay

A localized nucleolar DNA damage response facilitates recruitment of the homology-directed repair machinery independent of cell cycle stage.

A termination site for Xenopus RNA polymerase I also acts as an element of an adjacent promoter

Association of the nucleolar transcription factor UBF with the transcriptionally inactive rRNA genes of pronuclei and early Xenopus embryos ⬇️

Construction of synthetic nucleoli and what it tells us about propagation of sub-nuclear domains through cell division.

Construction of synthetic nucleoli in human cells reveals how a major functional nuclear domain is formed and propagated through cell division.

DNA repair: location, location, location

Dimerization and HMG box domains 1-3 present in Xenopus UBF are sufficient for its role in transcriptional enhancement.

HMG box 4 is the principal determinant of species specificity in the RNA polymerase I transcription factor UBF.

Human NORs, comprising rDNA arrays and functionally conserved distal elements, are located within dynamic chromosomal regions

Human acrocentric chromosomes with transcriptionally silent nucleolar organizer regions associate with nucleoli

Identification and cDNA cloning of a Xenopus nucleolar phosphoprotein, xNopp180, that is the homolog of the rat nucleolar protein Nopp140 ⬇️

Integrating the genomic architecture of human nucleolar organizer regions with the biophysical properties of nucleoli

Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis

Linker scanner mutagenesis of the Xenopus laevis ribosomal gene promoter

NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing

NORs on human acrocentric chromosome p-arms are active by default and can associate with nucleoli independently of rDNA

Nucleolar organizer regions: genomic 'dark matter' requiring illumination

Nucleolar protein upstream binding factor is sequestered into adenovirus DNA replication centres during infection without affecting RNA polymerase I location or ablating rRNA synthesis

Nucleolar reorganization in response to rDNA damage

Oddpols united: new insights into transcription by RNA polymerases I and III.

Processing and termination of RNA polymerase I transcripts

Recruitment of factors linking transcription and processing of pre-rRNA to NOR chromatin is UBF-dependent and occurs independent of transcription in human cells

Replication timing of pseudo-NORs.

Ribosome biogenesis: Achilles heel of cancer?

Structure-function analysis of Hmo1 unveils an ancestral organization of HMG-Box factors involved in ribosomal DNA transcription from yeast to human.

The Relationship Between Human Nucleolar Organizer Regions and Nucleoli, Probed by 3D-ImmunoFISH.

The Xenopus RNA polymerase I transcription factor, UBF, has a role in transcriptional enhancement distinct from that at the promoter.

The Xenopus ribosomal gene enhancers bind an essential polymerase I transcription factor, xUBF

The shared genomic architecture of human nucleolar organizer regions.

UBF binding in vivo is not restricted to regulatory sequences within the vertebrate ribosomal DNA repeat

UBF-binding site arrays form pseudo-NORs and sequester the RNA polymerase I transcription machinery.

Upstream binding factor stabilizes Rib 1, the TATA-binding-protein-containing Xenopus laevis RNA polymerase I transcription factor, by multiple protein interactions in a DNA-independent manner.

xUBF, an RNA polymerase I transcription factor, binds crossover DNA with low sequence specificity