List of works by Daniel F McAuley

16S pan-bacterial PCR can accurately identify patients with ventilator-associated pneumonia

scientific article published on 14 December 2016

A Randomized Clinical Trial of Hydroxymethylglutaryl– Coenzyme A Reductase Inhibition for Acute Lung Injury (The HARP Study)

scientific article published on 24 September 2010

A United Kingdom Register study of in-hospital outcomes of patients receiving extracorporeal carbon dioxide removal

scientific article published in May 2018

A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation

scientific article published on 5 September 2014

A national clinical scenario-based survey of clinicians' attitudes towards fresh frozen plasma transfusion for critically ill patients

scientific article published on 10 November 2010

A national survey of the diagnosis and management of suspected ventilator-associated pneumonia.

scientific article

A novel subpopulation of monocyte-like cells in the human lung after lipopolysaccharide inhalation

scientific article published on 20 January 2012

A potential role for keratinocyte growth factor and clarithromycin in the treatment of paraquat overdose.

scientific article published on 12 February 2010

A randomized controlled trial of peripheral blood mononuclear cell depletion in experimental human lung inflammation.

scientific article published in August 2013

A randomized controlled trial of tea tree oil (5%) body wash versus standard body wash to prevent colonization with methicillin-resistant Staphylococcus aureus (MRSA) in critically ill adults: research protocol.

scientific article

A role for whey acidic protein four-disulfide-core 12 (WFDC12) in the regulation of the inflammatory response in the lung

scientific article published on 13 March 2015

Accuracy of LightCycler(R) SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review protocol

scientific article

Accuracy of LightCycler(®) SeptiFast for the detection and identification of pathogens in the blood of patients with suspected sepsis: a systematic review and meta-analysis.

scientific article

Acute Respiratory Distress Syndrome Phenotypes and Identifying Treatable Traits. The Dawn of Personalized Medicine for ARDS.

scientific article published in February 2017

Acute lung failure

scientific article

Acute respiratory distress syndrome

scientific article published on 28 April 2016

Administration of mesenchymal stem cells during ECMO results in a rapid decline in oxygenator performance

scientific article published on 05 April 2018

Airway Inflammation and Host Responses in the Era of CFTR Modulators

scientific article published on 02 September 2020

An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome.

scientific article published in May 2017

An efficacy and mechanism evaluation study of Levosimendan for the Prevention of Acute oRgan Dysfunction in Sepsis (LeoPARDS): protocol for a randomized controlled trial.

scientific article

Aspirin as a potential treatment in sepsis or acute respiratory distress syndrome

scientific article

Aspirin reduces lipopolysaccharide-induced pulmonary inflammation in human models of ARDS.

scientific article published on 12 January 2017

Aspirin therapy in patients with acute respiratory distress syndrome (ARDS) is associated with reduced intensive care unit mortality: a prospective analysis

scientific article

Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children

scientific article (published 2014-06-10)

Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children: a cochrane systematic review and meta-analysis

scientific article

Benefits of statins in the critically ill: promising but not proven

scientific article published on 01 June 2011

Beta 2 antagonism in acute respiratory failure

scientific article published on 20 December 2010

Beta-Agonist Lung injury TrIal-2 (BALTI-2): a multicentre, randomised, double-blind, placebo-controlled trial and economic evaluation of intravenous infusion of salbutamol versus placebo in patients with acute respiratory distress syndrome

scientific article published in September 2013

Biological therapies in the acute respiratory distress syndrome

scientific article published on 05 April 2014

Characterisation of eppin function: expression and activity in the lung

scientific article published on 13 July 2017

Cigarette smokers have exaggerated alveolar barrier disruption in response to lipopolysaccharide inhalation.

scientific article published on 2 February 2016

Clara cell protein CC16. A new lung epithelial biomarker for acute lung injury

scientific article published on 01 June 2009

Clinical grade allogeneic human mesenchymal stem cells restore alveolar fluid clearance in human lungs rejected for transplantation

scientific article

Clinical review: Statins and trauma--a systematic review

scientific article published on 29 May 2013

Clinical trial design in prevention and treatment of acute respiratory distress syndrome

scientific article

Clinical trials in acute respiratory distress syndrome: challenges and opportunities.

scientific article

Combined dysfunctions of immune cells predict nosocomial infection in critically ill patients

scientific article

Comment on "Statin administration did not influence the progression of lung injury or associated organ failures in a cohort of patients with acute lung injury"

scientific article published on 14 May 2009

Comparison between mortality and airway colonization vs noncolonization with Candida species in critically ill adults

scientific article published on 11 September 2008

Core Outcomes in Ventilation Trials (COVenT): protocol for a core outcome set using a Delphi survey with a nested randomised trial and observational cohort study

scientific article published on 20 August 2015

Correction to: Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study

scientific article published on 14 November 2017

Corrigendum to 'Perioperative outcomes in the context of mode of anaesthesia for patients undergoing hip fracture surgery: systematic review and meta-analysis' [Br J Anaesth 2018; 120: 37-50]

scientific article published on 16 April 2018

Current practice in the management of new-onset atrial fibrillation in critically ill patients: a UK-wide survey

scientific article published on 8 September 2017

Decreased respiratory system compliance on the sixth day of mechanical ventilation is a predictor of death in patients with established acute lung injury.

scientific article

Designing a nurse-delivered delirium bundle: What intensive care unit staff, survivors, and their families think?

scientific article published on 23 March 2018

Development of a Core Outcome Set for studies evaluating the effects of anaesthesia on perioperative morbidity and mortality following hip fracture surgery

scientific article published on 03 October 2018

Diagnostic accuracy of pulmonary host inflammatory mediators in the exclusion of ventilator-acquired pneumonia.

scientific article

Effect of Protocolized Weaning With Early Extubation to Noninvasive Ventilation vs Invasive Weaning on Time to Liberation From Mechanical Ventilation Among Patients With Respiratory Failure: The Breathe Randomized Clinical Trial

scientific article published in The Journal of the American Medical Association

Effect of intravenous haloperidol on the duration of delirium and coma in critically ill patients (Hope-ICU): a randomised, double-blind, placebo-controlled trial

scientific article published on 21 August 2013

Effect of simvastatin on physiological and biological outcomes in patients undergoing esophagectomy: a randomized placebo-controlled trial

scientific article published in January 2014

Effectiveness of a programme of exercise on physical function in survivors of critical illness following discharge from the ICU: study protocol for a randomised controlled trial (REVIVE).

scientific article published on 27 April 2014

Effectiveness of an exercise programme on physical function in patients discharged from hospital following critical illness: a randomised controlled trial (the REVIVE trial).

scientific article published on 15 November 2016

Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial

scientific article published on 16 July 2016

Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries

scientific article published on February 2016

Erratum to: 'Effectiveness of biomarker-based exclusion of ventilator-acquired pneumonia to reduce antibiotic use (VAPrapid-2): study protocol for a randomised controlled trial'.

scientific article published on 26 September 2016

Erratum to: Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction - a randomised placebo-controlled trial (KARE): study protocol.

scientific article published on 11 May 2017

Evaluating early administration of the hydroxymethylglutaryl-CoA reductase inhibitor simvastatin in the prevention and treatment of delirium in critically ill ventilated patients (MoDUS trial): study protocol for a randomized controlled trial.

scientific article published on 16 May 2015

Evaluation of the ability of LL-37 to neutralise LPS in vitro and ex vivo.

scientific article

Evidence for chemokine synergy during neutrophil migration in ARDS

scientific article published on 05 August 2016

Evolution of the inflammatory and fibroproliferative responses during resolution and repair after ventilator-induced lung injury in the rat.

scientific article published in November 2011

Exchange protein directly activated by cyclic AMP (EPAC) activation reverses neutrophil dysfunction induced by β2-agonists, corticosteroids, and critical illness.

scientific article published on 17 September 2015

Extracorporeal carbon dioxide removal for lowering the risk of mechanical ventilation: research questions and clinical potential for the future

scientific article published on 01 November 2018

Extracorporeal carbon dioxide removal for patients with acute respiratory failure secondary to the acute respiratory distress syndrome: a systematic review

scientific article

Extravascular lung water indexed to predicted body weight is a novel predictor of intensive care unit mortality in patients with acute lung injury

scientific article published in January 2010

Fluid management and deresuscitation practices: A survey of critical care physicians

scientific article published on 13 May 2019

Fluid strategies and outcomes in patients with acute respiratory distress syndrome, systemic inflammatory response syndrome and sepsis: a protocol for a systematic review and meta-analysis

scientific article

Genetic mechanisms of critical illness in Covid-19

scientific article published on 11 December 2020

Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: insights from the LUNG SAFE prospective cohort study

scientific article published on 14 June 2017

High-volume haemofiltration for sepsis in adults.

scientific article

Hot off the breath: the 2009 H1N1 flu pandemic may be gone but should not be forgotten

scientific article published on 01 October 2010

How outcomes are defined in clinical trials of mechanically ventilated adults and children.

scientific article published on April 2014

Human lipopolysaccharide models provide mechanistic and therapeutic insights into systemic and pulmonary inflammation

scientific article published on 16 April 2020

Human mesenchymal stem cells reduce the severity of acute lung injury in a sheep model of bacterial pneumonia

scientific article

Human models of acute lung injury.

scientific article

Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database

Impact of non-pharmacological interventions on prevention and treatment of delirium in critically ill patients: protocol for a systematic review of quantitative and qualitative research

scientific article

Individual patient data analysis of tidal volumes used in three large randomized control trials involving patients with acute respiratory distress syndrome.

scientific article

Innate Lymphoid Cells Are the Predominant Source of IL-17A during the Early Pathogenesis of Acute Respiratory Distress Syndrome.

scientific article published on 21 October 2015

Keratinocyte growth factor for the treatment of the acute respiratory distress syndrome (KARE): a randomised, double-blind, placebo-controlled phase 2 trial.

scientific article published on 16 May 2017

Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction--a randomised placebo-controlled trial (KARE): study protocol.

scientific article published on 18 February 2013

Keratinocyte growth factor in acute lung injury--a work in progress.

scientific article published in May 2009

Keratinocyte growth factor promotes epithelial survival and resolution in a human model of lung injury

scientific article

Late mortality after acute hypoxic respiratory failure.

scientific article published on 5 August 2017

Latent class analysis of ARDS subphenotypes: a secondary analysis of the statins for acutely injured lungs from sepsis (SAILS) study

scientific article published on 05 October 2018

Levosimendan for the Prevention of Acute Organ Dysfunction in Sepsis.

scientific article published on 5 October 2016

Levosimendan to prevent acute organ dysfunction in sepsis: the LeoPARDS RCT

scientific article published on 16 November 2018

MMP expression and abnormal lung permeability are important determinants of outcome in IPF

scientific article published on 01 October 2008

MSC extracellular vesicles rescue mitochondrial dysfunction and improve barrier integrity in clinically relevant models of ARDS

scientific article published on 17 December 2020

Matrix metalloproteinases in acute lung injury: mediators of injury and drivers of repair.

scientific article published on 12 May 2011

Mechanical Ventilation in Adults with Acute Respiratory Distress Syndrome. Summary of the Experimental Evidence for the Clinical Practice Guideline.

scientific article

Mesenchymal Stromal Cells Modulate Macrophages in Clinically Relevant Lung Injury Models by Extracellular Vesicle Mitochondrial Transfer.

scientific article published on 9 June 2017

Mesenchymal stromal cells and the acute respiratory distress syndrome (ARDS): challenges for clinical application

scientific article published on 19 May 2015

Mesenchymal stromal cells for treatment of the acute respiratory distress syndrome: The beginning of the story

scientific article published on 21 May 2015

Mitochondrial Transfer via Tunneling Nanotubes is an Important Mechanism by Which Mesenchymal Stem Cells Enhance Macrophage Phagocytosis in the In Vitro and In Vivo Models of ARDS.

scientific article published on 5 April 2016

Moral distress in end-of-life care in the intensive care unit.

scientific article published on 4 December 2012

Nasal potential difference to detect Na+channel dysfunction in acute lung injury ⬇️

scientific article published on November 26, 2010

Noninvasive Ventilation of Patients with Acute Respiratory Distress Syndrome. Insights from the LUNG SAFE Study

scientific article published on 18 October 2016

Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury.

scientific article published on 29 January 2018

Novel pulmonary biomarkers in the diagnosis of VAP

scientific article published on 01 March 2010

Observational cohort study examining apolipoprotein E status and preoperative neuropsychological performance as predictors of post-operative delirium in an older elective arthroplasty population.

scientific article published on 5 April 2017

Out with the old or better use of the old? A quest in sedation*

scientific article published on 01 August 2013

Outcome of Acute Hypoxaemic Respiratory Failure. Insights from the Lung Safe Study

scientific article published on 17 December 2020

Palifermin for the protection and regeneration of epithelial tissues following injury: new findings in basic research and pre-clinical models

scientific article

Pathophysiology of pulmonary hypertension in acute lung injury.

scientific article

Patients' Perceptions of an Exercise Program Delivered Following Discharge From Hospital After Critical Illness (the Revive Trial).

scientific article

Peptoid Efficacy against Polymicrobial Biofilms Determined by Using Propidium Monoazide-Modified Quantitative PCR.

scientific article

Perioperative outcomes in the context of mode of anaesthesia for patients undergoing hip fracture surgery: systematic review and meta-analysis.

scientific article published on 24 November 2017

Pharmacological treatments in ARDS; a state-of-the-art update

scientific article

Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study.

scientific article published on 18 October 2016

Preliminary results of a prospective randomized trial of restrictive versus standard fluid regime in elective open abdominal aortic aneurysm repair

scientific article published on 01 July 2009

Prevention of post-operative complications by using a HMG-CoA reductase inhibitor in patients undergoing one-lung ventilation for non-cardiac surgery: study protocol for a randomised controlled trial

scientific article published on 18 December 2018

Prior colonisation with Candida species fails to guide empirical therapy for candidaemia in critically ill adults.

scientific article published on 16 September 2010

Pro: β-agonists in acute lung injury--the end of the story?

scientific article published on 01 September 2011

Prolonged glucocorticoid treatment in acute respiratory distress syndrome - Authors' reply.

scientific article published in April 2017

Protocolised non-invasive compared with invasive weaning from mechanical ventilation for adults in intensive care: the Breathe RCT

scientific article published on 01 September 2019

Quantifying the Effects of Prior Acetyl-Salicylic Acid on Sepsis-Related Deaths: An Individual Patient Data Meta-Analysis Using Propensity Matching.

scientific article published on 09 August 2017

RECOVERY- Respiratory Support: Respiratory Strategies for patients with suspected or proven COVID-19 respiratory failure; Continuous Positive Airway Pressure, High-flow Nasal Oxygen, and standard care: A structured summary of a study protocol for a

scientific article published on 29 July 2020

Randomised controlled trial of GM-CSF in critically ill patients with impaired neutrophil phagocytosis

scientific article published on 31 July 2018

Rapid detection of health-care-associated bloodstream infection in critical care using multipathogen real-time polymerase chain reaction technology: a diagnostic accuracy study and systematic review

scientific article published on May 2015

Reciting the months of the year backwards: what is a 'normal' score?

scientific article published on 01 May 2015

Referral to an extracorporeal membrane oxygenation center and mortality among patients with severe 2009 influenza A(H1N1).

scientific article

Reliability of blood pressure determination with the Finapres with altered physiological states or pharmacodynamic conditions ⬇️

scientific article published on 01 August 1997

Reply to Letter: "Effect of Simvastatin on Physiological and Biological Outcomes in Patients Undergoing Esophagectomy: A Randomized Placebo-controlled Trial".

scientific article published in December 2015

Reply: Importance of the kidney, vessels, and heart with administration of β2 adrenergic receptor agonists in patients susceptible to acute respiratory distress syndrome.

scientific article published on June 2014

Reply: The Alveolar Macrophage and Acute Respiratory Distress Syndrome: A Silent Actor?

scientific article published on 01 February 2014

Respiratory infections cause the release of extracellular vesicles: implications in exacerbation of asthma/COPD

scientific article

Risk factors for acute organ failure in intensive care unit patients who receive respiratory support in the absence of non-respiratory organ failure: an international prospective cohort study

scientific article published on 12 December 2012

Role responsibilities in mechanical ventilation and weaning in pediatric intensive care units: a national survey.

scientific article published in May 2013

Routine delirium monitoring in a UK critical care unit.

scientific article published on 09 February 2009

SMAD inhibition attenuates epithelial to mesenchymal transition by primary keratinocytes in vitro

scientific article published in July 2014

Salbutamol up-regulates matrix metalloproteinase-9 in the alveolar space in the acute respiratory distress syndrome.

scientific article published in July 2009

Sedation AND Weaning In Children (SANDWICH): protocol for a cluster randomised stepped wedge trial

scientific article published on 10 November 2019

Sedation/drugs used in intensive care sedation

scientific article

Sequelae and rehabilitation after critical illness

scientific article published on December 2011

Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers

scientific article published on 26 March 2009

Simvastatin decreases the level of heparin-binding protein in patients with acute lung injury.

scientific article

Simvastatin for patients with acute respiratory distress syndrome: long-term outcomes and cost-effectiveness from a randomised controlled trial ⬇️

scientific article

Simvastatin for the prevention and treatment of delirium in critically ill, mechanically ventilated patients (MoDUS): a cost-effectiveness analysis.

scientific article

Simvastatin pre-treatment improves survival and mitochondrial function in a 3-day fluid-resuscitated rat model of sepsis

scientific article published on 15 February 2017

Soluble endostatin is a novel inhibitor of epithelial repair in idiopathic pulmonary fibrosis

scientific article published on 13 October 2008

Statin therapy for acute respiratory distress syndrome: an individual patient data meta-analysis of randomised clinical trials

scientific article

Statin use and risk of delirium in the critically ill.

scientific article published on March 2014

Statins and sepsis: potential benefit but more unanswered questions

scientific article published on 01 April 2013

Statins exposure and delirium risk: a winning association?*.

scientific article published in August 2014

Statins in patients with sepsis and ARDS: is it over? We are not sure.

scientific article

Stem cells for respiratory failure.

scientific article published on February 2015

Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization.

scientific article published on 21 November 2012

Targeting Siglecs with a sialic acid-decorated nanoparticle abrogates inflammation.

scientific article published on September 2015

Tea tree oil (5%) body wash versus standard care (Johnson's Baby Softwash) to prevent colonization with methicillin-resistant Staphylococcus aureus in critically ill adults: a randomized controlled trial

scientific article published on 07 January 2013

The Naturally Occurring Host Defense Peptide, LL-37, and Its Truncated Mimetics KE-18 and KR-12 Have Selected Biocidal and Antibiofilm Activities Against Candida albicans, Staphylococcus aureus, and Escherichia coli In vitro.

scientific article published on 31 March 2017

The Swine Flu Triage (SwiFT) study: development and ongoing refinement of a triage tool to provide regular information to guide immediate policy and practice for the use of critical care services during the H1N1 swine influenza pandemic.

scientific article

The beta agonist lung injury trial prevention. A randomized controlled trial.

scientific article published on March 2014

The effectiveness of non-pharmacological interventions in reducing the incidence and duration of delirium in critically ill patients: a systematic review and meta-analysis

scientific article published on 30 November 2018

The impact of a PCR assay for candidemia on antifungal drug prescribing in critical care: an interrupted time series pilot study.

scientific article published on 30 March 2010

The impact of the acute respiratory distress syndrome on outcome after oesophagectomy

scientific article published on 20 July 2016

The inflammatory response to extracorporeal membrane oxygenation (ECMO): a review of the pathophysiology

scientific article

Thorax protocol review: working with trialists to improve trial quality

scientific article published on 5 April 2016

Type XVIII collagen degradation products in acute lung injury

scientific article

Unexpected Role for Adaptive αβTh17 Cells in Acute Respiratory Distress Syndrome

scientific article published on 22 May 2015

Variation in Definition of Prolonged Mechanical Ventilation.

scientific article published on 13 June 2017

Ventilator-associated pneumonia is characterized by excessive release of neutrophil proteases in the lung

scientific article published on 01 December 2012

Where next for cell-based therapy in ARDS

scientific article published on 12 November 2018

miR-31 dysregulation in cystic fibrosis airways contributes to increased pulmonary cathepsin S production

scientific article

pRotective vEntilation with veno-venouS lung assisT in respiratory failure: A protocol for a multicentre randomised controlled trial of extracorporeal carbon dioxide removal in patients with acute hypoxaemic respiratory failure

scientific article published in May 2017

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