List of works - Toke Bek

24-h ambulatory blood pressure and retinopathy in normoalbuminuric IDDM patients ⬇️

scientific article published on January 1, 1998

A nationwide study on the incidence of rhegmatogenous retinal detachment in Denmark, with emphasis on the risk of the fellow eye.

scientific article published in August 2014

ARTERIAL OXYGEN SATURATION IN NEOVASCULARIZATIONS IN PROLIFERATIVE DIABETIC RETINOPATHY.

scientific article published on 3 October 2017

ATP-induced relaxation of porcine retinal arterioles in vitro depends on prostaglandin E synthesized in the perivascular retinal tissue.

scientific article published on 7 April 2010

Activation of Veratridine Sensitive Sodium Channels, But not Electrical Field Stimulation, Dilates Porcine Retinal Arterioles with Preserved Perivascular Tissue.

scientific article published on 14 September 2017

Acute hyperinsulinemia increases the contraction of retinal arterioles induced by elevated blood pressure

scientific article published on 20 September 2013

Adeno-associated virus-delivered polycistronic microRNA-clusters for knockdown of vascular endothelial growth factor in vivo.

scientific article

Age, sex, and type of medication predict the effect of anti-VEGF treatment on central retinal thickness in wet age-related macular degeneration.

scientific article published on 8 March 2018

Altered aquaporin expression in glaucoma eyes

scientific article published on 31 January 2014

Ambulatory pulse pressure, decreased nocturnal blood pressure reduction and progression of nephropathy in type 2 diabetic patients.

scientific article published on 29 January 2009

Aquaporins 6-12 in the human eye ⬇️

scientific article published on September 13, 2012

Binocular Fixation Reduces Fixational Eye Movements in the Worst Eye of Patients with Center-Involving Diabetic Macular Edema

scientific article published on 07 July 2017

Constriction of porcine retinal arterioles induced by endothelin-1 and the thromboxane analogue U46619 in vitro decreases with increasing vascular branching level.

scientific article

Corneal versus scleral tunnel incision in cataract surgery: a randomized study

scientific article published on 01 April 1997

Development and validation of a multiple-choice questionnaire-based theoretical test in direct ophthalmoscopy

scientific article published on 28 February 2019

Diabetic retinopathy in people with Type 2 diabetes and obesity treated by Roux-en-Y gastric bypass compared with non-operated controls: with focus on the role of diabetes remission in a cross-sectional and a 6-year follow-up study

scientific article published on 26 December 2018

Diabetic retinopathy in pregnancy during tight metabolic control

scientific article published on 01 May 2000

Diameter changes of retinal arterioles during acute hypoxia in vivo are modified by the inhibition of nitric oxide and prostaglandin synthesis

scientific article published on 8 September 2014

Differential diameter responses in macular and peripheral retinal arterioles may contribute to the regional distribution of diabetic retinopathy lesions

scientific article published on 11 November 2010

Differential effects of nitric oxide and cyclo-oxygenase inhibition on the diameter of porcine retinal vessels with different caliber during hypoxia ex vivo

scientific article published on 7 April 2017

Discovery of α-Substituted Imidazole-4-acetic Acid Analogues as a Novel Class of ρ1 γ-Aminobutyric Acid Type A Receptor Antagonists with Effect on Retinal Vascular Tone

scientific article published on 13 September 2016

Dorzolamide-induced relaxation of intraocular porcine ciliary arteries in vitro depends on nitric oxide and the vascular endothelium

scientific article published on 20 July 2012

Dorzolamide-induced relaxation of porcine retinal arterioles in vitro depends on nitric oxide but not on acidosis in vascular smooth muscle cells

scientific article published on 20 September 2014

Dual effect of prostaglandins on isolated intraocular porcine ciliary arteries.

scientific article

Dual effects of adenosine on the tone of porcine retinal arterioles in vitro

scientific article published on 19 March 2014

Evidence-based Danish guidelines for screening of diabetic retinopathy

scientific article published on 11 October 2018

Extracellular l-arginine Enhances Relaxations Induced by Opening of Calcium-Activated SKCa Channels in Porcine Retinal Arteriole

scientific article published on 25 April 2019

Eye complications in type 2 diabetes mellitus

scientific article

Fine structure in diabetic retinopathy lesions as observed by adaptive optics imaging. A qualitative study

scientific article published on 12 June 2014

Fourier analysis of video-keratographic data A tool for separation of spherical, regular astigmatic and irregular astigmatic corneal power components ⬇️

scientific article published on May 1, 1995

GABA-induced relaxation of porcine retinal arterioles in vitro depends on inhibition from the perivascular retina and is mediated by GABAC receptors

scientific article published on 05 June 2012

Hypoxia-induced relaxation of porcine retinal arterioles in vitro depends on inducible NO synthase and EP4 receptor stimulation in the perivascular retina

scientific article published on 25 January 2015

Improvement of mild retinopathy in type 2 diabetic patients correlates with narrowing of retinal arterioles. A prospective observational study

scientific article

Incidence and Risk for Developing Proliferative Diabetic Retinopathy after Photocoagulation for Diabetic Maculopathy

scientific article published on 10 January 2020

Incidence and risk factors for neovascular age-related macular degeneration in the fellow eye

scientific article published on 10 August 2018

Incidence of neuromyelitis optica spectrum disorder in the Central Denmark Region.

scientific article

Individual risk assessment and information technology to optimise screening frequency for diabetic retinopathy

scientific article

Individualized optimization of the screening interval for diabetic retinopathy: a new model

scientific article published on 06 April 2010

Inner retinal ischaemia: current understanding and needs for further investigations.

scientific article published on 24 March 2009

Intraocular currents, Bernoulli's principle and non-drainage scleral buckling for rhegmatogenous retinal detachment

scientific article published on 19 January 2018

In Vivo Knockout of the Vegfa Gene by Lentiviral Delivery of CRISPR/Cas9 in Mouse Retinal Pigment Epithelium Cells.

scientific article published on 21 September 2017

Is lack of autonomic nerves in retinal vessels a protection from electrical stimulation generated by activity in visual neurons?

scientific article published on 2 November 2017

Lack of correlation between short-term dynamics of diabetic retinopathy lesions and the arterial blood pressure ⬇️

scientific article published on 03 October 2010

Lack of differences in the regional variation of oxygen saturation in larger retinal vessels in diabetic maculopathy and proliferative diabetic retinopathy

scientific article published on 23 August 2016

Lack of effect of nitroglycerin on the diameter response of larger retinal arterioles in normal persons during hypoxia

scientific article published on 30 November 2015

Lack of effect of short-term treatment with amlodipine and lisinopril on retinal autoregulation in normotensive patients with type 1 diabetes and mild diabetic retinopathy

scientific article published on 19 March 2010

Laws of physics help explain capillary non-perfusion in diabetic retinopathy.

scientific article published on 19 January 2018

Mitochondrial dysfunction and diabetic retinopathy

scientific article published on 22 July 2016

Multigenic lentiviral vectors for combined and tissue-specific expression of miRNA- and protein-based antiangiogenic factors

scientific article published on 28 January 2015

Neurogenic contractions in intraocular porcine ciliary arteries are mediated by α₂-adrenoceptors and NPY₁ receptors and are inhibited by prostaglandin E₂ acting on prejunctional EP₄ receptors.

scientific article

Niels Ehlers 1930-2016.

scientific article published in November 2016

Novel Cellular Bouton Structure Activated by ATP in the Vascular Wall of Porcine Retinal Arterioles ⬇️

scientific article published on August 4, 2010

Openers of small conductance calcium-activated potassium channels selectively enhance NO-mediated bradykinin vasodilatation in porcine retinal arterioles.

scientific article published on July 2010

Pericyte modulation by a functional antibody obtained by a novel single-cell selection strategy.

scientific article published on 25 February 2017

Post-hypoxic constriction of retinal arterioles is impaired during nitric oxide and cyclo-oxygenase inhibition and in diabetic patients without retinopathy

scientific article

Preserved Pressure Autoregulation but Disturbed Cyclo-Oxygenase and Nitric Oxide Effects on Retinal Arterioles during Acute Hypoxia in Diabetic Patients without Retinopathy

scientific article published on 08 January 2016

Pulse pressure and diurnal blood pressure variation: association with micro- and macrovascular complications in type 2 diabetes.

scientific article

Reduced Expression of Cytoskeletal and Extracellular Matrix Genes in Human Adult Retinal Pigment Epithelium Cells Exposed to Simulated Microgravity.

scientific article published on 14 November 2016

Reduced baseline diameter and contraction of peripheral retinal arterioles immediately after remote ischemia in diabetic patients

scientific article published on 04 July 2019

Reduction of choroidal neovascularization in mice by adeno-associated virus-delivered anti-vascular endothelial growth factor short hairpin RNA.

scientific article

Regional morphology and pathophysiology of retinal vascular disease.

scientific article published on 26 July 2013

Relaxation of porcine retinal arterioles during acute hypoxia in vitro depends on prostaglandin and NO synthesis in the perivascular retina

scientific article published on 14 June 2013

Relaxation of porcine retinal arterioles exposed to hypercholesterolemia in vivo is modified by hepatic LDL-receptor deficiency and diabetes mellitus.

scientific article published on 24 June 2013

Reoperation for rhegmatogenous retinal detachment as quality indicator for disease management: a register study

scientific article

Reply: Is automated screening for DR indeed not yet ready as stated by Grauslund et al?

scientific article published on 19 September 2019

Response to "Epidemiology of neuromyelitis optica spectrum disorder''

scientific article published on 01 June 2018

Retinal Oximetry Discovers Novel Biomarkers in Retinal and Brain Diseases.

scientific article

Retinal Oxygen Saturation Correlates With Visual Acuity but Does Not Predict Outcome After Anti-VEGF Treatment in Central Retinal Vein Occlusion.

scientific article published in May 2017

Retinal oxygen saturation is an independent risk factor for the severity of diabetic retinopathy

scientific article published on 18 October 2018

Retinal vasodilatation in the affected eye but reduced pressure autoregulation of both eyes in unilateral Coats' disease

scientific article published on 06 March 2019

Retinal vessel reactivity is not attenuated in patients with type 2 diabetes compared with matched controls and is associated with peripheral endothelial function in controls

scientific article published on 03 June 2019

Role of calcium-activated potassium channels with small conductance in bradykinin-induced vasodilation of porcine retinal arterioles.

scientific article published on 28 February 2009

Spatial distribution of early red lesions is a risk factor for development of vision-threatening diabetic retinopathy.

scientific article published on 7 September 2017

Spontaneous high frequency diameter oscillations of larger retinal arterioles are reduced in type 2 diabetes mellitus.

scientific article published on 21 January 2013

Subretinal Saline Protects the Neuroretina From Thermic Damage During Laser Induction of Experimental Choroidal Neovascularization in Pigs

scientific article published on 01 June 2021

Subretinal neovascularization as the only ocular sign of osteogenesis imperfecta: a case report.

scientific article

Suppression of Choroidal Neovascularization by AAV-Based Dual-Acting Antiangiogenic Gene Therapy

article

Suppression of Choroidal Neovascularization in Mice by Subretinal Delivery of Multigenic Lentiviral Vectors Encoding Anti-Angiogenic MicroRNAs

scientific article

Systemic risk factors contribute differently to the development of proliferative diabetic retinopathy and clinically significant macular oedema

scientific article published on 21 July 2020

The CAPOS mutation in ATP1A3 alters Na/K-ATPase function and results in auditory neuropathy which has implications for management

scientific article published on 5 January 2018

The Diameter of Retinal Arterioles Is Unaffected by Intravascular Administration of the Adenosine A2A Receptor Agonist Regadenoson in Normal Persons

scientific article published on 15 May 2019

The Diameter of Retinal Vessels Is Affected by Transient Ischemia of the Arm in Normal Persons.

scientific article published in October 2017

The Oxygen Saturation in Vascular Abnormalities Depends on the Extent of Arteriovenous Shunting in Diabetic Retinopathy

scientific article published on 01 September 2019

The Retinal Oxygen Saturation Measured by Dual Wavelength Oximetry in Larger Retinal Vessels is Influenced by the Linear Velocity of the Blood

scientific article published on 05 October 2018

The Systemic Blood Pressure and Oxygen Saturation in Retinal Arterioles Predict the Effect of Intravitreal Anti-VEGF Treatment on Diabetic Maculopathy.

scientific article published in October 2016

The area of fixation covaries with short-term changes in visual acuity after anti-vascular endothelial growth factor treatment in patients with diabetic macular oedema

scientific article published on 24 April 2018

The diameter response of retinal arterioles in diabetic maculopathy is reduced during hypoxia and is unaffected by the inhibition of cyclo-oxygenase and nitric oxide synthesis.

scientific article published on 07 June 2016

The frequency of small saccades during fixation is age independent in children between 5 and 16 years of age.

scientific article published on 18 August 2016

The oxygen saturation in retinal vessels from diabetic patients depends on the severity and type of vision-threatening retinopathy

scientific article

The predictive value of subjective symptoms and clinical signs for the presence of treatment‐requiring exudative age‐related macular degeneration ⬇️

scientific article published on January 14, 2011

The prevalence of diabetic retinopathy in patients with screen-detected type 2 diabetes in Denmark: the ADDITION study.

scientific article published on 23 September 2008

The relationships between risk factors and the distribution of retinopathy lesions in type 2 diabetes

scientific article published on October 2006

The role of retinopathy distribution and other lesion types for the definition of examination intervals during screening for diabetic retinopathy.

scientific article

The vasodilating effect of glucose differs among vessels at different branching level in the porcine retina ex vivo

scientific article published on 10 November 2018

The vasodilating effects of insulin and lactate are increased in precapillary arterioles in the porcine retina ex vivo

scientific article

Time to steroid treatment in severe acute optic neuritis

scientific article published on 22 June 2018

Tone regulation in giraffe retinal arterioles

scientific article published on 25 January 2016

Topical treatment for 1 week with latanoprost but not diclofenac reduces the diameter of dilated retinal arterioles in patients with type 1 diabetes mellitus and mild retinopathy

scientific article published on 05 July 2011

Translational research in retinal vascular disease. An approach

scientific article published on 22 February 2019

Use of the retinal vessel analyzer in ocular blood flow research

scientific article published in November 2010

Variable involvement of the perivascular retinal tissue in carbonic anhydrase inhibitor induced relaxation of porcine retinal arterioles in vitro.

scientific article published in October 2007

Voltage-gated calcium channels are involved in the regulation of calcium oscillations in vascular smooth muscle cells from isolated porcine retinal arterioles.

scientific article published on 20 April 2010

[Purtscher's retinopathy as a complication to a cemented resection tumour prosthesis] ⬇️

scientific article published on 01 October 2019

List of works by Toke Bek

24-h ambulatory blood pressure and retinopathy in normoalbuminuric IDDM patients ⬇️

A nationwide study on the incidence of rhegmatogenous retinal detachment in Denmark, with emphasis on the risk of the fellow eye.

ARTERIAL OXYGEN SATURATION IN NEOVASCULARIZATIONS IN PROLIFERATIVE DIABETIC RETINOPATHY.

ATP-induced relaxation of porcine retinal arterioles in vitro depends on prostaglandin E synthesized in the perivascular retinal tissue.

Activation of Veratridine Sensitive Sodium Channels, But not Electrical Field Stimulation, Dilates Porcine Retinal Arterioles with Preserved Perivascular Tissue.

Acute hyperinsulinemia increases the contraction of retinal arterioles induced by elevated blood pressure

Adeno-associated virus-delivered polycistronic microRNA-clusters for knockdown of vascular endothelial growth factor in vivo.

Age, sex, and type of medication predict the effect of anti-VEGF treatment on central retinal thickness in wet age-related macular degeneration.

Altered aquaporin expression in glaucoma eyes

Ambulatory pulse pressure, decreased nocturnal blood pressure reduction and progression of nephropathy in type 2 diabetic patients.

Aquaporins 6-12 in the human eye ⬇️

Binocular Fixation Reduces Fixational Eye Movements in the Worst Eye of Patients with Center-Involving Diabetic Macular Edema

Constriction of porcine retinal arterioles induced by endothelin-1 and the thromboxane analogue U46619 in vitro decreases with increasing vascular branching level.

Corneal versus scleral tunnel incision in cataract surgery: a randomized study

Development and validation of a multiple-choice questionnaire-based theoretical test in direct ophthalmoscopy

Diabetic retinopathy in people with Type 2 diabetes and obesity treated by Roux-en-Y gastric bypass compared with non-operated controls: with focus on the role of diabetes remission in a cross-sectional and a 6-year follow-up study

Diabetic retinopathy in pregnancy during tight metabolic control

Diameter changes of retinal arterioles during acute hypoxia in vivo are modified by the inhibition of nitric oxide and prostaglandin synthesis

Differential diameter responses in macular and peripheral retinal arterioles may contribute to the regional distribution of diabetic retinopathy lesions

Differential effects of nitric oxide and cyclo-oxygenase inhibition on the diameter of porcine retinal vessels with different caliber during hypoxia ex vivo

Discovery of α-Substituted Imidazole-4-acetic Acid Analogues as a Novel Class of ρ1 γ-Aminobutyric Acid Type A Receptor Antagonists with Effect on Retinal Vascular Tone

Dorzolamide-induced relaxation of intraocular porcine ciliary arteries in vitro depends on nitric oxide and the vascular endothelium

Dorzolamide-induced relaxation of porcine retinal arterioles in vitro depends on nitric oxide but not on acidosis in vascular smooth muscle cells

Dual effect of prostaglandins on isolated intraocular porcine ciliary arteries.

Dual effects of adenosine on the tone of porcine retinal arterioles in vitro

Evidence-based Danish guidelines for screening of diabetic retinopathy

Extracellular l-arginine Enhances Relaxations Induced by Opening of Calcium-Activated SKCa Channels in Porcine Retinal Arteriole

Eye complications in type 2 diabetes mellitus

Fine structure in diabetic retinopathy lesions as observed by adaptive optics imaging. A qualitative study

Fourier analysis of video-keratographic data A tool for separation of spherical, regular astigmatic and irregular astigmatic corneal power components ⬇️

GABA-induced relaxation of porcine retinal arterioles in vitro depends on inhibition from the perivascular retina and is mediated by GABAC receptors

Hypoxia-induced relaxation of porcine retinal arterioles in vitro depends on inducible NO synthase and EP4 receptor stimulation in the perivascular retina

Improvement of mild retinopathy in type 2 diabetic patients correlates with narrowing of retinal arterioles. A prospective observational study

Incidence and Risk for Developing Proliferative Diabetic Retinopathy after Photocoagulation for Diabetic Maculopathy

Incidence and risk factors for neovascular age-related macular degeneration in the fellow eye

Incidence of neuromyelitis optica spectrum disorder in the Central Denmark Region.

Individual risk assessment and information technology to optimise screening frequency for diabetic retinopathy

Individualized optimization of the screening interval for diabetic retinopathy: a new model

Inner retinal ischaemia: current understanding and needs for further investigations.

Intraocular currents, Bernoulli's principle and non-drainage scleral buckling for rhegmatogenous retinal detachment

In Vivo Knockout of the Vegfa Gene by Lentiviral Delivery of CRISPR/Cas9 in Mouse Retinal Pigment Epithelium Cells.

Is lack of autonomic nerves in retinal vessels a protection from electrical stimulation generated by activity in visual neurons?

Lack of correlation between short-term dynamics of diabetic retinopathy lesions and the arterial blood pressure ⬇️

Lack of differences in the regional variation of oxygen saturation in larger retinal vessels in diabetic maculopathy and proliferative diabetic retinopathy

Lack of effect of nitroglycerin on the diameter response of larger retinal arterioles in normal persons during hypoxia

Lack of effect of short-term treatment with amlodipine and lisinopril on retinal autoregulation in normotensive patients with type 1 diabetes and mild diabetic retinopathy

Laws of physics help explain capillary non-perfusion in diabetic retinopathy.

Mitochondrial dysfunction and diabetic retinopathy

Multigenic lentiviral vectors for combined and tissue-specific expression of miRNA- and protein-based antiangiogenic factors

Neurogenic contractions in intraocular porcine ciliary arteries are mediated by α₂-adrenoceptors and NPY₁ receptors and are inhibited by prostaglandin E₂ acting on prejunctional EP₄ receptors.

Niels Ehlers 1930-2016.

Novel Cellular Bouton Structure Activated by ATP in the Vascular Wall of Porcine Retinal Arterioles ⬇️

Openers of small conductance calcium-activated potassium channels selectively enhance NO-mediated bradykinin vasodilatation in porcine retinal arterioles.

Pericyte modulation by a functional antibody obtained by a novel single-cell selection strategy.

Post-hypoxic constriction of retinal arterioles is impaired during nitric oxide and cyclo-oxygenase inhibition and in diabetic patients without retinopathy

Preserved Pressure Autoregulation but Disturbed Cyclo-Oxygenase and Nitric Oxide Effects on Retinal Arterioles during Acute Hypoxia in Diabetic Patients without Retinopathy

Pulse pressure and diurnal blood pressure variation: association with micro- and macrovascular complications in type 2 diabetes.

Reduced Expression of Cytoskeletal and Extracellular Matrix Genes in Human Adult Retinal Pigment Epithelium Cells Exposed to Simulated Microgravity.

Reduced baseline diameter and contraction of peripheral retinal arterioles immediately after remote ischemia in diabetic patients

Reduction of choroidal neovascularization in mice by adeno-associated virus-delivered anti-vascular endothelial growth factor short hairpin RNA.

Regional morphology and pathophysiology of retinal vascular disease.

Relaxation of porcine retinal arterioles during acute hypoxia in vitro depends on prostaglandin and NO synthesis in the perivascular retina

Relaxation of porcine retinal arterioles exposed to hypercholesterolemia in vivo is modified by hepatic LDL-receptor deficiency and diabetes mellitus.

Reoperation for rhegmatogenous retinal detachment as quality indicator for disease management: a register study

Reply: Is automated screening for DR indeed not yet ready as stated by Grauslund et al?

Response to "Epidemiology of neuromyelitis optica spectrum disorder''

Retinal Oximetry Discovers Novel Biomarkers in Retinal and Brain Diseases.

Retinal Oxygen Saturation Correlates With Visual Acuity but Does Not Predict Outcome After Anti-VEGF Treatment in Central Retinal Vein Occlusion.

Retinal oxygen saturation is an independent risk factor for the severity of diabetic retinopathy

Retinal vasodilatation in the affected eye but reduced pressure autoregulation of both eyes in unilateral Coats' disease

Retinal vessel reactivity is not attenuated in patients with type 2 diabetes compared with matched controls and is associated with peripheral endothelial function in controls

Role of calcium-activated potassium channels with small conductance in bradykinin-induced vasodilation of porcine retinal arterioles.

Spatial distribution of early red lesions is a risk factor for development of vision-threatening diabetic retinopathy.

Spontaneous high frequency diameter oscillations of larger retinal arterioles are reduced in type 2 diabetes mellitus.

Subretinal Saline Protects the Neuroretina From Thermic Damage During Laser Induction of Experimental Choroidal Neovascularization in Pigs

Subretinal neovascularization as the only ocular sign of osteogenesis imperfecta: a case report.

Suppression of Choroidal Neovascularization by AAV-Based Dual-Acting Antiangiogenic Gene Therapy

Suppression of Choroidal Neovascularization in Mice by Subretinal Delivery of Multigenic Lentiviral Vectors Encoding Anti-Angiogenic MicroRNAs

Systemic risk factors contribute differently to the development of proliferative diabetic retinopathy and clinically significant macular oedema