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List of works by Grant Pearce

A helical LIR mediates the interaction between the retroviral restriction factor Trim5α and the mammalian autophagy related ATG8 proteins

scientific article published in Journal of Biological Chemistry

A tetrameric structure is not essential for activity in dihydrodipicolinate synthase (DHDPS) from Mycobacterium tuberculosis.

scientific article

Aggregation and Fibrillogenesis of Proteins not Associated with Disease: A Few Case Studies

scientific article published on January 1, 2012

Allelic Dropout During Polymerase Chain Reaction due to G-Quadruplex Structures and DNA Methylation Is Widespread at Imprinted Human Loci.

scientific article published on 30 January 2017

An optimized SEC-SAXS system enabling high X-ray dose for rapid SAXS assessment with correlated UV measurements for biomolecular structure analysis

scholarly article

An unexpected sticking point for carboxysome assembly

scientific article published on 01 February 2019

Archaeal Lsm rings as stable self-assembling tectons for protein nanofabrication.

scientific article published on 27 May 2017

Catalytic by-product formation and ligand binding by ribulose bisphosphate carboxylases from different phylogenies.

scientific article

Characterisation of the First Enzymes Committed to Lysine Biosynthesis in Arabidopsis thaliana

scientific article

Characterization of dihydrodipicolinate reductase from Thermotoga maritima reveals evolution of substrate binding kinetics

scientific article

Characterization of monomeric dihydrodipicolinate synthase variant reveals the importance of substrate binding in optimizing oligomerization

scientific article

Characterization of spinach ribulose-1,5-bisphosphate carboxylase/oxygenase activase isoforms reveals hexameric assemblies with increased thermal stability

scientific article published on 01 December 2014

Cloning, expression and crystallization of dihydrodipicolinate reductase from methicillin-resistant Staphylococcus aureus.

scientific article published on 25 December 2009

Conserved main-chain peptide distortions: A proposed role for Ile203 in catalysis by dihydrodipicolinate synthase

scientific article

Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis

scientific article

Crystal, Solution and In silico Structural Studies of Dihydrodipicolinate Synthase from the Common Grapevine

scientific article

Crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase 2 from Arabidopsis thaliana

scientific article published on 27 October 2011

DNA G-quadruplexes show strong interaction with DNA methyltransferases in vitro.

scientific article

Dihydrodipicolinate Synthase: Structure, Dynamics, Function, and Evolution

scientific article published on January 2017

Dihydrodipicolinate synthase from Thermotoga maritima.

scientific article published on December 2006

Dihydrodipicolinate synthase is not inhibited by its substrate, (S)-aspartate beta-semialdehyde.

scientific article published on February 2004

Disruption of quaternary structure in Escherichia coli dihydrodipicolinate synthase (DHDPS) generates a functional monomer that is no longer inhibited by lysine.

scientific article published on 13 August 2010

Does domain swapping improve the stability of RNase A?

scientific article published on 3 March 2009

Evolution of quaternary structure in a homotetrameric enzyme

scientific article

Formation of amyloid-like fibrils by ovalbumin and related proteins under conditions relevant to food processing

scientific article published on 01 January 2007

Formation of supramolecular protein structures on gold surfaces

scientific article published on 15 November 2017

From knock-out phenotype to three-dimensional structure of a promising antibiotic target from Streptococcus pneumoniae

scientific article (publication date: 2013)

Functional and solution structure studies of amino sugar deacetylase and deaminase enzymes from Staphylococcus aureus

scientific article published on 26 November 2018

Immobilization of organophosphate hydrolase on an amyloid fibril nanoscaffold: towards bioremediation and chemical detoxification.

scientific article published on 23 November 2010

Immobilization of tobacco etch virus (TEV) protease on a high surface area protein nanofibril scaffold

scientific article published on 08 September 2018

Inhibiting dihydrodipicolinate synthase across species: towards specificity for pathogens?

scientific journal article

Multivalency regulates activity in an intrinsically disordered transcription factor

scientific article published on 03 August 2018

Multivalency regulates activity in an intrinsically disordered transcription factor.

scientific article

Mutating the tight-dimer interface of dihydrodipicolinate synthase disrupts the enzyme quaternary structure: toward a monomeric enzyme

scientific article

Peroxiredoxin is a Versatile Self-Assembling Tecton for Protein Nanotechnology

scientific article published on 01 May 2014

Plant DHDPR forms a dimer with unique secondary structure features that preclude higher-order assembly.

scientific article published on 29 November 2017

Quaternary structure influences the peroxidase activity of peroxiredoxin 3.

scientific article published on 10 February 2018

Role of arginine 138 in the catalysis and regulation of Escherichia coli dihydrodipicolinate synthase

scientific article published in October 2005

Self-assembly of toroidal proteins explored using native mass spectrometry

scientific article published on 18 June 2018

Small oligomers of ribulose-bisphosphate carboxylase/oxygenase (Rubisco) activase are required for biological activity

scientific article

Spacer capture and integration by a type I-F Cas1-Cas2-3 CRISPR adaptation complex.

scientific article published on 13 June 2017

Structural and functional analyses of Rubisco from arctic diatom species reveal unusual posttranslational modifications

scientific article published on 20 June 2018

Structure and Function of Cyanobacterial DHDPS and DHDPR

scientific article

Structure and inhibition of N-acetylneuraminate lyase from methicillin-resistant Staphylococcus aureus

scientific article

Structure of a hyperthermostable dimeric archaeal Rubisco from Hyperthermus butylicus

scientific article published on 28 May 2019

The epigenetic regulator Smchd1 contains a functional GHKL-type ATPase domain.

scientific article published on 8 April 2016

The relationship between side reactions and slow inhibition of ribulose-bisphosphate carboxylase revealed by a loop 6 mutant of the tobacco enzyme.

scientific article