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List of works by Paul J. Brett

A nonsense mutation in TLR5 is associated with survival and reduced IL-10 and TNF-α levels in human melioidosis

scientific article

Burkholderia mallei and Burkholderia pseudomallei cluster 1 type VI secretion system gene expression is negatively regulated by iron and zinc

scientific article

Burkholderia mallei cluster 1 type VI secretion mutants exhibit growth and actin polymerization defects in RAW 264.7 murine macrophages

scientific article

Burkholderia mallei expresses a unique lipopolysaccharide mixture that is a potent activator of human Toll-like receptor 4 complexes

scientific article

Burkholderia pseudomallei Capsular Polysaccharide Recognition by a Monoclonal Antibody Reveals Key Details toward a Biodefense Vaccine and Diagnostics against Melioidosis

scientific article published on 21 July 2015

Burkholderia pseudomallei and Burkholderia mallei vaccines: Are we close to clinical trials?

scientific article published on 20 March 2017

Burkholderia pseudomallei capsular polysaccharide conjugates provide protection against acute melioidosis

scientific article

Burkholderia pseudomallei type III secretion system mutants exhibit delayed vacuolar escape phenotypes in RAW 264.7 murine macrophages

scientific article published on 28 April 2008

Characterization of Burkholderia pseudomallei and Burkholderia pseudomallei-like strains

scientific article published in April 1997

Characterization of oligopeptides that cross-react with carbohydrate-specific antibodies by real time kinetics, in-solution competition enzyme-linked immunosorbent assay, and immunological analyses

scientific article

Colony morphology variation of Burkholderia pseudomallei is associated with antigenic variation and O-polysaccharide modification

scientific article published on 16 March 2015

Comparison of O-polysaccharide and hemolysin co-regulated protein as target antigens for serodiagnosis of melioidosis

scientific article

Contribution of murine IgG Fc regions to antibody binding to the capsule of Burkholderia pseudomallei

scientific article published on 20 April 2016

Current studies on the pathogenesis of melioidosis

scientific article

Deciphering minimal antigenic epitopes associated with Burkholderia pseudomallei and Burkholderia mallei lipopolysaccharide O-antigens

scientific article

Detailed structural analysis of the O-polysaccharide expressed by Burkholderia thailandensis E264 ⬇️

scientific article published on October 11, 2012

Development of Immunoassays for Burkholderia pseudomallei Typical and Atypical Lipopolysaccharide Strain Typing

scientific article published on 19 December 2016

Development of Rapid Enzyme-Linked Immunosorbent Assays for Detection of Antibodies to Burkholderia pseudomallei

scientific article published on 24 February 2016

Development of Subunit Vaccines that Provide High Level Protection and Sterilizing Immunity Against Acute Inhalational Melioidosis

scientific article published on 6 November 2017

Development of a prototype lateral flow immunoassay (LFI) for the rapid diagnosis of melioidosis

scientific article

Development of capsular polysaccharide-based glycoconjugates for immunization against melioidosis and glanders ⬇️

scientific article published on August 15, 2012

Development of novel O-polysaccharide based glycoconjugates for immunization against glanders ⬇️

scientific article published on November 27, 2012

Evaluation of Polysaccharide-Based Latex Agglutination Assays for the Rapid Detection of Antibodies to Burkholderia pseudomallei

scientific article

Genome-scale analysis of the genes that contribute to Burkholderia pseudomallei biofilm formation identifies a crucial exopolysaccharide biosynthesis gene cluster

scientific article published on 28 June 2017

Identification of circulating bacterial antigens by in vivo microbial antigen discovery

scientific article

Identification of genes encoding secreted proteins using mini-OphoA mutagenesis.

scientific article published in January 2003

Identification of the acid phosphatase (acpA) gene homologues in pathogenic and non-pathogenic Burkholderia spp. facilitates TnphoA mutagenesis

scientific article

Immune response to recombinant Burkholderia pseudomallei FliC.

scientific article published on 14 June 2018

In vivo Distribution and Clearance of Purified Capsular Polysaccharide from Burkholderia pseudomallei in a Murine Model

scientific article

Insights into the complex regulation of rpoS in Borrelia burgdorferi

scientific article

Isolation and characterization of Pseudomonas pseudomallei flagellin proteins

scientific article published on May 1994

Melioidosis diagnostic workshop, 2013.

scientific article published in February 2015

Molecular and Physical Characterization of Burkholderia mallei O Antigens ⬇️

scientific article published on February 1, 2002

Molecular insights into Burkholderia pseudomallei and Burkholderia mallei pathogenesis

scientific article

Mutagenesis of Burkholderia pseudomallei with Tn5-OT182: isolation of motility mutants and molecular characterization of the flagellin structural gene

scientific article published on April 1997

Note: Burkholderia thailandensis sp. nov., a Burkholderia pseudomallei-like species ⬇️

scientific article published on January 1, 1998

Pathogenesis of and immunity to melioidosis

scientific article

Proteomic analysis of the Burkholderia pseudomallei type II secretome reveals hydrolytic enzymes, novel proteins, and the deubiquitinase TssM

scientific article

Retrospective Analysis of Fever and Sepsis Patients from Cambodia Reveals Serological Evidence of Melioidosis

scientific article published on 12 February 2018

Specificity and functional activity of anti-Burkholderia pseudomallei polysaccharide antibodies ⬇️

scientific article published on September 1, 1997

Structural analysis of capsular polysaccharides expressed by Burkholderia mallei and Burkholderia pseudomallei ⬇️

scientific article published on December 23, 2011

Structural and immunological characterization of Burkholderia pseudomallei O-polysaccharide-flagellin protein conjugates

scientific article published on July 1996

The cluster 1 type VI secretion system is a major virulence determinant in Burkholderia pseudomallei

scientific article

The type II O-antigenic polysaccharide moiety of Burkholderia pseudomallei lipopolysaccharide is required for serum resistance and virulence

scientific article published in December 1998

The wbiA locus is required for the 2-O-acetylation of lipopolysaccharides expressed by Burkholderia pseudomallei and Burkholderia thailandensis

scientific article published in January 2003

Thermoregulation of Biofilm Formation in Burkholderia pseudomallei Is Disrupted by Mutation of a Putative Diguanylate Cyclase

scientific article published on 12 December 2016

Treponema denticola TroR is a manganese- and iron-dependent transcriptional repressor

scientific article published on 27 August 2008

Use of Rapid Enzyme-Linked Immunosorbent Assay for Serological Screening of Melioidosis in Myanmar

scientific article published on 19 March 2018

iNOS activity is critical for the clearance of Burkholderia mallei from infected RAW 264.7 murine macrophages

scientific article

pH Alkalinization by Chloroquine Suppresses Pathogenic Burkholderia Type 6 Secretion System 1 and Multinucleated Giant Cells

scientific article published on 31 October 2016

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