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List of works by John D Davis

A Mechanistic Systems Pharmacology Model for Prediction of LDL Cholesterol Lowering by PCSK9 Antagonism in Human Dyslipidemic Populations

scientific article

A comparison of the prediction accuracy of two IVIVC modelling techniques.

scientific article published in August 2008

A population approach to in vitro-in vivo correlation modelling for compounds with nonlinear kinetics.

scientific article

Activity, pharmacokinetics and safety of lersivirine (UK-453,061), a next-generation nonnucleoside reverse transcriptase inhibitor, during 7-day monotherapy in HIV-1-infected patients

scientific article published on 01 October 2009

Application of physiologically based pharmacokinetic modeling to understanding the clinical pharmacokinetics of UK-369,003

scientific article published on 30 March 2011

Atovaquone has no effect on the pharmacokinetics of phenytoin in healthy male volunteers.

scientific article published on August 1996

Challenges and Opportunities for Quantitative Clinical Pharmacology in Cancer Immunotherapy: Something Old, Something New, Something Borrowed, and Something Blue

scientific article published on 11 September 2015

Combining "Bottom-up" and "Top-down" Approaches to Assess the Impact of Food and Gastric pH on Pictilisib (GDC-0941) Pharmacokinetics.

scientific article

Conjunctivitis in dupilumab clinical trials

scientific article published on 07 May 2019

Dupilumab shows long-term safety and efficacy in patients with moderate to severe atopic dermatitis enrolled in a phase 3 open-label extension study

scientific article published on 30 July 2019

Effect of norfloxacin on theophylline disposition: a comparison with other fluoroquinolones

scientific article published on 01 February 1995

Effect of rifampin and rifabutin on the pharmacokinetics of lersivirine and effect of lersivirine on the pharmacokinetics of rifabutin and 25-O-desacetyl-rifabutin in healthy subjects.

scientific article

Effects of ketoconazole and valproic acid on the pharmacokinetics of the next generation NNRTI, lersivirine (UK-453,061), in healthy adult subjects.

scientific article published on May 2012

Efficacy of Dupilumab in Different Racial Subgroups of Adults With Moderate-to-Severe Atopic Dermatitis in Three Randomized, Placebo-Controlled Phase 3 Trials

scientific article published on 01 August 2019

Evaluation of Potential Disease-Mediated Drug-Drug Interaction in Patients With Moderate-to-Severe Atopic Dermatitis Receiving Dupilumab.

scientific article published on 2 March 2018

Exploratory Population PK Analysis of Dupilumab, a Fully Human Monoclonal Antibody Against IL-4Rα, in Atopic Dermatitis Patients and Normal Volunteers.

scientific article

Grapefruit juice-drug interaction studies as a method to assess the extent of intestinal availability: utility and limitations.

scientific article published on October 2008

In vivo-in vitro correlation (IVIVC) modeling incorporating a convolution step

scientific article published on 01 June 2001

Interpretation and optimization of the dissolution specifications for a modified release product with an in vivo-in vitro correlation (IVIVC)

scientific article published on 01 March 2004

Investigation of multiple dose citalopram on the pharmacokinetics and pharmacodynamics of racemic warfarin.

scientific article published on August 1997

Investigation of regional mechanisms responsible for poor oral absorption in humans of a modified release preparation of the alpha-adrenoreceptor antagonist, 4-amino-6,7-dimethoxy-2-(5-methanesulfonamido-1,2,3,4 tetrahydroisoquinol-2-yl)-5-(2-pyridy

scientific article published on 11 October 2007

Modeling and Simulation to Support Phase 2 Dose Selection for RG7652, a Fully Human Monoclonal Antibody Against Proprotein Convertase Subtilisin/Kexin Type 9.

scientific article published on 31 March 2015

Pharmacokinetic Effects of Coadministration of Lersivirine with Raltegravir or Maraviroc in Healthy Subjects ⬇️

scientific article published on November 28, 2011

Pharmacokinetic interactions of maraviroc with darunavir-ritonavir, etravirine, and etravirine-darunavir-ritonavir in healthy volunteers: results of two drug interaction trials.

scientific article

Population pharmacokinetic analysis from phase I and phase II studies of the humanized monovalent antibody, onartuzumab (MetMAb), in patients with advanced solid tumors.

scientific article

Pre-clinical pharmacokinetics of UK-453,061, a novel non-nucleoside reverse transcriptase inhibitor (NNRTI), and use of in silico physiologically based prediction tools to predict the oral pharmacokinetics of UK-453,061 in man

scientific article published in June 2008

Projecting human pharmacokinetics of monoclonal antibodies from nonclinical data: comparative evaluation of prediction approaches in early drug development.

scientific article

REGN-COV2, a Neutralizing Antibody Cocktail, in Outpatients with Covid-19

scientific article published on 17 December 2020

Relationship between enoxacin and ciprofloxacin plasma concentrations and theophylline disposition

scientific article published on 01 October 1994

Role of pharmacokinetics in establishing bioequivalence for orally inhaled drug products: workshop summary report.

scientific article published on 31 March 2011

Safety and tolerability of lersivirine, a nonnucleoside reverse transcriptase inhibitor, during a 28-day, randomized, placebo-controlled, Phase I clinical study in healthy male volunteers ⬇️

scientific article published on October 1, 2010

Simultaneous assay of fluoroquinolones and theophylline in plasma by high-performance liquid chromatography

scientific article published on 01 November 1993

Species differences in the multiple-dose pharmacokinetics of the non-nucleoside reverse transcriptase inhibitor (NNRTI) UK-453,061 in animals and man: implications for safety considerations

scientific article published on 01 July 2009

Subcutaneous REGEN-COV Antibody Combination to Prevent Covid-19

scientific article published on 04 August 2021

The effect of lersivirine, a next-generation NNRTI, on the pharmacokinetics of midazolam and oral contraceptives in healthy subjects ⬇️

scientific article published on April 22, 2012

The pharmacokinetics of lersivirine (UK-453,061) and HIV-1 protease inhibitor coadministration in healthy subjects.

scientific article published in May 2012

The use of beat-to-beat electrocardiogram analysis to distinguish QT/QTc interval changes caused by moxifloxacin from those caused by vardenafil

scientific article published on 03 August 2011

Translational pharmacokinetic-pharmacodynamic modelling; application to cardiovascular safety data for PF-00821385, a novel HIV agent

scientific article

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