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List of works by Judy E. Garber

A Cross-Cancer Genetic Association Analysis of the DNA Repair and DNA Damage Signaling Pathways for Lung, Ovary, Prostate, Breast, and Colorectal Cancer

scientific article

A HIF1alpha regulatory loop links hypoxia and mitochondrial signals in pheochromocytomas

scientific article

A Randomized Multicenter Phase II Study of Docosahexaenoic Acid in Patients with a History of Breast Cancer, Premalignant Lesions or Benign Breast Disease.

scientific article published on 16 February 2018

A Randomized Phase IIb Study of Low-dose Tamoxifen in Chest-irradiated Cancer Survivors at risk for Breast Cancer

scientific article published on 03 December 2020

A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk

article

A candidate precursor to pelvic serous cancer (p53 signature) and its prevalence in ovaries and fallopian tubes from women with BRCA mutations

scientific article

A comparison of cancer risk assessment and testing outcomes in patients from underserved vs. tertiary care settings

scientific article published on 18 November 2017

A counseling framework for moderate-penetrance colorectal cancer susceptibility genes

scientific article published in March 2018

A hereditary nonpolyposis colorectal carcinoma case associated with hypermethylation of the MLH1 gene in normal tissue and loss of heterozygosity of the unmethylated allele in the resulting microsatellite instability-high tumor

scientific article

A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

scientific article

A nonsynonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriers

scientific article

A pedigree-based prediction model identifies carriers of deleterious de novo mutations in families with Li-Fraumeni syndrome

scientific article published on 18 August 2020

A population-based study of Ashkenazi Jewish women's attitudes toward genetic discrimination and BRCA1/2 testing

scientific article published on 01 September 2002

A randomized Phase II study of veliparib with temozolomide or carboplatin/paclitaxel versus placebo with carboplatin/paclitaxel in BRCA1/2 metastatic breast cancer: design and rationale

scientific article published on 14 October 2016

A rare TP53 mutation predominant in Ashkenazi Jews confers risk of multiple cancers

scientific article published on 16 July 2020

A short-term biomarker modulation study of simvastatin in women at increased risk of a new breast cancer

scientific article published on 11 November 2011

AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 study

scientific article published on July 2007

Accuracy of cancer family histories: comparison of two breast cancer syndromes

scientific article published on 01 January 2004

Addressing sexual dysfunction after risk-reducing salpingo-oophorectomy: effects of a brief, psychosexual intervention

scientific article

Age at menarche and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers

article

American Society of Clinical Oncology policy statement: the role of the oncologist in cancer prevention and risk assessment

scientific article published on 15 December 2008

American society of clinical oncology clinical practice guideline update on the use of pharmacologic interventions including tamoxifen, raloxifene, and aromatase inhibition for breast cancer risk reduction

scientific article published on 26 May 2009

An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers

scientific article published on 25 April 2015

Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers

scientific article

Assigning clinical meaning to somatic and germ-line whole-exome sequencing data in a prospective cancer precision medicine study.

scientific article

Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer

scientific article published on 09 February 2016

Association of Tumor-Infiltrating Lymphocytes with Homologous Recombination Deficiency and BRCA1/2 Status in Patients with Early Triple-Negative Breast Cancer: A Pooled Analysis

scientific article published on 03 December 2019

Association of a Polygenic Risk Score With Breast Cancer Among Women Carriers of High- and Moderate-Risk Breast Cancer Genes

scientific article published on 01 July 2020

Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3.

scientific article

Association of germline variation with the survival of women with BRCA1/2 pathogenic variants and breast cancer

scientific article published on 10 September 2020

Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality

scientific article

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

scientific article

Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers

scientific article published on 31 December 2014

Attitudes toward childbearing and prenatal testing in individuals undergoing genetic testing for Lynch Syndrome ⬇️

scientific article published on September 1, 2011

Atypical ductal hyperplasia in men with gynecomastia: what is their breast cancer risk?

scientific article published on 21 January 2019

Augmentation of venlafaxine and selective serotonin reuptake inhibitors with zolpidem improves sleep and quality of life in breast cancer patients with hot flashes: a randomized, double-blind, placebo-controlled trial

scientific article published in September 2010

BRCA Challenge: BRCA Exchange as a global resource for variants in BRCA1 and BRCA2

scientific article published on 26 December 2018

BRCA1 and BRCA2 Mutation Testing in Young Women With Breast Cancer

scientific article

BRCA1 and BRCA2 Pathogenic Sequence Variants in Women of African Origin or Ancestry

scientific article published on 03 July 2019

BRCA1 haploinsufficiency for replication stress suppression in primary cells

scientific article

BRCA1/2 genetic testing in the community setting

scientific article published on November 2002

BRCA1/2 testing: therapeutic implications for breast cancer management

article by Nadine M Tung & Judy E Garber published 1 July 2018 in British Journal of Cancer

BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers

scientific article

BRCA2 germline mutations in male breast cancer cases and breast cancer families

scientific article published on 01 May 1996

BRCAPRO validation, sensitivity of genetic testing of BRCA1/BRCA2, and prevalence of other breast cancer susceptibility genes

article

Basal cytokeratin and epidermal growth factor receptor expression are not predictive of BRCA1 mutation status in women with triple-negative breast cancers

scientific article published on July 2009

Baseline Surveillance in Li-Fraumeni Syndrome Using Whole-Body Magnetic Resonance Imaging: A Meta-analysis

scientific article

Bilateral prophylactic mastectomy reduces breast cancer risk in BRCA1 and BRCA2 mutation carriers: the PROSE Study Group

scientific article published on 23 February 2004

Bilateral prophylactic oophorectomy and bilateral prophylactic mastectomy in a prospective cohort of unaffected BRCA1 and BRCA2 mutation carriers

scientific article published in December 2007

Breast Cancer Risk Reduction, Version 2.2015

scientific article published on 01 July 2015

Breast Cancer Risk and Follow-up Recommendations for Young Women Diagnosed with Atypical Hyperplasia and Lobular Carcinoma In Situ (LCIS).

scientific article published on 05 August 2015

Breast Cancer Screening and Diagnosis, Version 3.2018, NCCN Clinical Practice Guidelines in Oncology

scientific article published on 01 November 2018

Breast MRI wire-guided excisional biopsy: specimen size as compared to mammogram wire-guided excisional biopsy and implications for use.

scientific article published on 11 September 2007

Breast and ovarian cancer risk and risk reduction in Jewish BRCA1/2 mutation carriers

scientific article

Breast cancer phenotype in women with TP53 germline mutations: a Li-Fraumeni syndrome consortium effort

scientific article published on 04 March 2012

Breast cancer risk reduction

scientific article published on September 2007

Breast cancer risk reduction.

scientific article

Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.

scientific article

Breast cancer screening and diagnosis

scientific article published on 01 May 2006

Breast cancer screening in women previously treated for Hodgkin's disease: a prospective cohort study

scientific article published in April 2002

Breast-feeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers

scientific article published in July 2004

Brief assessment of parents' attitudes toward testing minor children for hereditary breast/ovarian cancer genes: development and validation of the Pediatric BRCA1/2 Testing Attitudes Scale (P-TAS)

scientific article published on April 2008

CANCER. The cancer predisposition revolution

scientific article published on 01 May 2016

Cancer Risks Associated With Germline PALB2 Pathogenic Variants: An International Study of 524 Families

scientific article published on 16 December 2019

Cancer Screening Recommendations for Individuals with Li-Fraumeni Syndrome

scientific article

Cancer Survivorship Care: An Opportunity to Revisit Cancer Genetics

scientific article published on 28 December 2015

Cancer prevention and the American Society of Clinical Oncology

scientific article published on 07 September 2004

Cancer variation associated with the position of the mutation in the BRCA2 gene

scientific article published in January 2004

Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article

Challenges to the Development of New Agents for Molecularly Defined Patient Subsets: Lessons FromBRCA1/2-Associated Breast Cancer

article

Characteristics of individuals with breast cancer rearrangements in BRCA1 and BRCA2.

scientific article published on 12 February 2014

Cholesterol, Cholesterol-Lowering Medication Use, and Breast Cancer Outcome in the BIG 1-98 Study

scientific article published on 13 February 2017

Clinical characteristics and outcomes of BRCA-associated ovarian cancer: genotype and survival

scientific article published in January 2012

Clinical outcome of triple negative breast cancer in BRCA1 mutation carriers and noncarriers ⬇️

scientific article published on January 24, 2011

Clinical presentation correlates with the type of mismatch repair gene involved in hereditary nonpolyposis colon cancer

scientific article published in March 2004

Common genetic variants and modification of penetrance of BRCA2-associated breast cancer

scientific article

Common genetic variation at BARD1 is not associated with breast cancer risk in BRCA1 or BRCA2 mutation carriers

scientific article

Comparison of up-front cash cards and checks as incentives for participation in a clinician survey: a study within a trial

scientific article published on 17 August 2020

Complementary Medicine Use before and 1 Year Following Genetic Testing for BRCA1/2 Mutations

scientific article published on 01 January 2006

Complementary and alternative medicine use among women with breast cancer

scientific article published on 01 September 2002

Complementary medicine use among women enrolled in a genetic testing program ⬇️

scientific article published on April 1, 2003

Comprehensive molecular analysis of mismatch repair gene defects in suspected Lynch syndrome (hereditary nonpolyposis colorectal cancer) cases

scientific article published on 18 August 2009

Conflicting Interpretation of Genetic Variants and Cancer Risk by Commercial Laboratories as Assessed by the Prospective Registry of Multiplex Testing

scientific article published on 12 September 2016

Contralateral breast cancer in BRCA1/BRCA2 mutation carriers: the story of the other side

scientific article published on 26 October 2009

Correction: Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer

scholarly article by Mia M Gaudet published in November 2010

Correction: Common Genetic Variants and Modification of Penetrance of BRCA2-Associated Breast Cancer.

scientific article

Counselling framework for moderate-penetrance cancer-susceptibility mutations

scientific article

Customized breast cancer risk assessment in an ambulatory clinic: a portal for identifying women at risk

scientific article published on 21 January 2019

DNA Repair Protein Biomarkers Associated with Time to Recurrence in Triple-Negative Breast Cancer ⬇️

scientific article published on December 1, 2010

DNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriers

scientific article

Decisional Outcomes of Maternal Disclosure of BRCA1/2 Genetic Test Results to Children ⬇️

scientific article published on July 1, 2013

Developing a Novel Model to Improve Research and care for Cancer Survivors: a Feasibility Study

scientific article published on 20 October 2017

Development and Validation of a Clinical Polygenic Risk Score to Predict Breast Cancer Risk

scientific article published on 08 June 2020

Development and testing of the KnowGene scale to assess general cancer genetic knowledge related to multigene panel testing

scientific article published on 13 April 2019

Differences in Cancer Phenotypes Among Frequent <i>CHEK2</i> Variants and Implications for Clinical Care—Checking <i>CHEK2</i>

scientific article published in 2022

Differences in TP53 Mutation Carrier Phenotypes Emerge From Panel-Based Testing

scientific article published on 26 February 2018

Discrimination of Germline EGFR T790M Mutations in Plasma Cell-Free DNA Allows Study of Prevalence Across 31,414 Cancer Patients.

scientific article published on 25 September 2017

Disparities in uptake of BRCA1/2 genetic testing in a randomized trial of telephone counseling.

scientific article

Distress and the parenting dynamic among BRCA1/2 tested mothers and their partners.

scientific article published on 24 June 2013

Does MRI predict pathologic tumor response in women with breast cancer undergoing preoperative chemotherapy?

scientific article published on November 2007

Ductal lavage of fluid-yielding and non-fluid-yielding ducts in BRCA1 and BRCA2 mutation carriers and other women at high inherited breast cancer risk

scientific article published in May 2005

E3 ligase RFWD3 is a novel modulator of stalled fork stability in BRCA2-deficient cells

scientific article published on 01 June 2020

Effect of Factor V Leiden and prothrombin G20210-->A mutations on thromboembolic risk in the national surgical adjuvant breast and bowel project breast cancer prevention trial.

scientific article

Effect of Radiotherapy After Breast-Conserving Treatment in Women With Breast Cancer and Germline BRCA1/2 Mutations

article by Lori J Pierce et al published 1 October 2000 in Journal of Clinical Oncology

Effect of Short-Term Hormone Replacement Therapy on Breast Cancer Risk Reduction After Bilateral Prophylactic Oophorectomy in BRCA1 and BRCA2 Mutation Carriers: The PROSE Study Group

article by Timothy R. Rebbeck et al published November 2005 in Journal of Clinical Oncology

Effect of Vitamin D Supplementation on Breast Cancer Biomarkers: CALGB 70806 (Alliance) Study Design and Baseline Data

scientific article published in July 2016

Efficacy of neoadjuvant Cisplatin in triple-negative breast cancer

scientific article

Embedding a genetic counselor into oncology clinics improves testing rates and timeliness for women with ovarian cancer

scientific article published on 20 November 2020

Epidemiologic correlates of ovarian cortical inclusion cysts (CICs) support a dual precursor pathway to pelvic epithelial cancer

scientific article published on 16 July 2009

Epidemiology, Biology, Treatment, and Prevention of Ductal Carcinoma In Situ (DCIS)

scholarly article published November 2018

Erratum: Author Correction: The contribution of pathogenic variants in breast cancer susceptibility genes to familial breast cancer risk

scientific article published on 7 November 2017

Estrogen receptor positive breast cancers in BRCA1 mutation carriers: clinical risk factors and pathologic features

scientific article

Estrogen receptor signaling is reprogrammed during breast tumorigenesis

scientific article published on 20 May 2019

Ethical Issues in Cancer Genetics: 1) Whose Information Is It?

article

Ethical issues in cancer genetics: I 1) whose information is it?

article

Evaluation of established breast cancer risk factors as modifiers of BRCA1 or BRCA2: a multi-center case-only analysis

scientific article

Evaluation of microsatellite instability and immunohistochemistry for the prediction of germ-line MSH2 and MLH1 mutations in hereditary nonpolyposis colon cancer families

scientific article published on 01 June 2002

Evolutionary Pathways in BRCA1-Associated Breast Tumors ⬇️

scientific article published on April 10, 2012

Exemestane for breast-cancer prevention in postmenopausal women

scientific article published on 4 June 2011

F18-fluorodeoxyglucose-positron emission tomography/computed tomography screening in Li-Fraumeni syndrome.

scientific article

Factor V Leiden mutation and thromboembolism risk in women receiving adjuvant tamoxifen for breast cancer

scientific article

Factors associated with genetic testing distress in patients tested for Lynch Syndrome or Hereditary Breast and Ovarian Cancer Syndrome.

scientific article published on 10 March 2011

Familial Gastrointestinal Stromal Tumor Syndrome: Phenotypic and Molecular Features in a Kindred

scientific article published on 01 April 2005

Familial cancer database online

scientific article published on 01 October 2008

Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

scientific article

Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes

article

Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes

scientific article published on 07 January 2020

Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer

scientific article

Frequency of Germline Mutations in 25 Cancer Susceptibility Genes in a Sequential Series of Patients With Breast Cancer

scientific article published on 14 March 2016

Frequency of Triple-Negative Breast Cancer in BRCA1 Mutation Carriers: Comparison Between Common Ashkenazi Jewish and Other Mutations ⬇️

scientific article published on October 22, 2012

Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next-generation sequencing with a 25-gene panel

scientific article published on 03 September 2014

Frequent met oncogene amplification in a Brca1/Trp53 mouse model of mammary tumorigenesis

scientific article published on April 2006

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

scientific article published on 7 September 2016

Gastric cancer in individuals with Li-Fraumeni syndrome

scientific article published on July 2011

Genetic Testing for Breast Cancer Susceptibility Should Be Offered before Unilateral Abdominally Based Free Flap Breast Reconstruction

scientific article published on 01 July 2019

Genetic analysis of eight breast-ovarian cancer families with suspected BRCA1 mutations

scientific article published on January 1995

Genetic and functional analysis of CHEK2 (CHK2) variants in multiethnic cohorts

scientific article

Genetic counseling and testing for breast-ovarian cancer susceptibility: what do women want? ⬇️

scientific article published on 01 January 1998

Genetic testing for hereditary breast and ovarian cancer and the USPSTF recommendations

scientific article published on 01 July 2019

Genetic variation in IGF2 and HTRA1 and breast cancer risk among BRCA1 and BRCA2 carriers

scientific article

Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1 and BRCA2 carriers

scientific article published on January 2009

Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2015.

scientific article published in February 2016

Genetic/familial high-risk assessment: breast and ovarian

scientific article

Genetic/familial high-risk assessment: breast and ovarian

scientific article published on 01 May 2010

Genetic/familial high-risk assessment: breast and ovarian, version 1.2014

scientific article published on 01 September 2014

Genome-wide association and transcriptome studies identify target genes and risk loci for breast cancer

article

Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses

scientific article published on 18 May 2020

Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

scientific article (publication date: 2013)

Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33.

scholarly article

Genotype-phenotype associations among panel-based TP53+ subjects

scientific article published on 20 May 2019

Germline TP53 mutations and the changing landscape of Li-Fraumeni syndrome

scientific article published on June 2014

Germline mutations in lysine specific demethylase 1 (LSD1/KDM1A) confer susceptibility to multiple myeloma

scientific article published on 20 March 2018

Germline mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms

scientific article published on May 14, 1992

Guidelines for genetic risk assessment of hereditary breast and ovarian cancer: early disagreements and low utilization

scientific article published on 20 May 2009

Haplotype and phenotype analysis of nine recurrent BRCA2 mutations in 111 families: results of an international study

scientific article

Haplotype structure in Ashkenazi Jewish BRCA1 and BRCA2 mutation carriers

scientific article

Height and Body Mass Index as Modifiers of Breast Cancer Risk in BRCA1/2 Mutation Carriers: A Mendelian Randomization Study

scientific article published on 01 April 2019

Hereditary cancer predisposition syndromes

scientific article

Hereditary diffuse gastric cancer: association with lobular breast cancer

scientific article

Histopathologic features of breast cancer in Li-Fraumeni syndrome

scientific article published on 07 July 2020

Homologous Recombination Deficiency (HRD) Score Predicts Response to Platinum-Containing Neoadjuvant Chemotherapy in Patients with Triple-Negative Breast Cancer.

scientific article

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

scientific article

Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

scientific article published on 27 April 2016

Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus

scientific article

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

scientific article published on 12 January 2015

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

scientific article published on 23 October 2017

Immune Escape in Breast Cancer During In Situ to Invasive Carcinoma Transition

scientific article published on 26 June 2017

Impact of genetic testing on endometrial cancer risk-reducing practices in women at risk for Lynch syndrome ⬇️

scientific article published on August 29, 2012

Impact of genetic testing on risk-reducing behavior in women at risk for hereditary gynecologic cancer syndromes

scientific article published on 25 May 2010

Impact of mismatch repair (MMR) genetic test result on perceived cancer risk and cancer screening.

scientific article published on 25 May 2010

Inadvertent use of aromatase inhibitors in patients with breast cancer with residual ovarian function: cases and lessons

scientific article published on 01 June 2006

Incidental breast carcinoma: incidence, management, and outcomes in 4804 bilateral reduction mammoplasties

scientific article published on 17 July 2019

Information needs of mothers regarding communicating BRCA1/2 cancer genetic test results to their children

scientific article published on January 2007

Informing models of cancer genetic care in the era of multigene panel testing with patient-led recommendations

scientific article published on 26 August 2020

Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women

scientific article

Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer

scientific article

Intentions for risk-reducing surgery among high-risk women referred for BRCA1/BRCA2 genetic counseling.

scientific article

Large genomic rearrangement in BRCA1 and BRCA2 and clinical characteristics of men with breast cancer in the United States

scientific article published on 01 June 2007

Leveraging premalignant biology for immune-based cancer prevention

scientific article published on 16 September 2016

Li-Fraumeni Exploration Consortium Data Coordinating Center: Building an Interactive Web-based Resource for Collaborative International Cancer Epidemiology Research for a Rare Condition

scientific article published on 10 March 2020

Li-Fraumeni Syndrome

scientific article published on 21 November 2019

Li-Fraumeni syndrome: not a straightforward diagnosis anymore-the interpretation of pathogenic variants of low allele frequency and the differences between germline PVs, mosaicism, and clonal hematopoiesis

scientific article published on 18 September 2019

Li-Fraumeni syndrome: report of a clinical research workshop and creation of a research consortium

scientific article published on 29 August 2012

Local therapy in BRCA1 and BRCA2 mutation carriers with operable breast cancer: comparison of breast conservation and mastectomy

scientific article

Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2.

scientific article

Male patients with diagnoses of both breast cancer and prostate cancer

scientific article

Managing hereditary breast cancer risk in women with and without ovarian cancer

scientific article

Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers

scientific article published on 19 June 2019

Mixing Mutation Location With Carcinogen Exposure: A Recipe for Tissue Specificity in BRCA2-Associated Cancers?

scientific article published on 01 September 2018

Modification of BRCA1-Associated Breast and Ovarian Cancer Risk by BRCA1-Interacting Genes

scientific article

Modification of ovarian cancer risk by BRCA1/2-interacting genes in a multicenter cohort of BRCA1/2 mutation carriers

scientific article published on 07 July 2009

Molecular definition of breast tumor heterogeneity

scientific article

Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics.

scientific article published on 13 June 2013

Mortality after bilateral salpingo-oophorectomy in BRCA1 and BRCA2 mutation carriers: a prospective cohort study

scientific article

Multicenter Phase II Study of Lurbinectedin in BRCA-Mutated and Unselected Metastatic Advanced Breast Cancer and Biomarker Assessment Substudy

scientific article published on 21 September 2018

Multimodal assessment of protein functional deficiency supports pathogenicity of BRCA1 p.V1688del

scientific article published on 25 August 2009

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

Multiplex Genetic Testing for Cancer Susceptibility: Out on the High Wire Without a Net?

Mutation Rates in Cancer Susceptibility Genes in Patients With Breast Cancer With Multiple Primary Cancers

scientific article published on 19 August 2020

Mutational Spectrum in a Worldwide Study of 29,700 Families with BRCA1 or BRCA2 Mutations

scientific article published on 15 February 2018

Mutational processes molding the genomes of 21 breast cancers

scientific article

NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2017.

scientific article published on January 2017

NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 1.2020

scientific article published on 01 April 2020

NCCN clinical practice guidelines in oncology: breast cancer screening and diagnosis

scientific article

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

scientific article published in May 2015

Novel Pathogenic Germline Variant of the Adenomatous Polyposis Coli (APC) Gene, p.S2627Gfs*12 Identified in a Mild Phenotype of APC-Associated Polyposis: A Case Report

scientific article published on 11 December 2020

Occult ovarian cancers identified at risk-reducing salpingo-oophorectomy in a prospective cohort of BRCA1/2 mutation carriers

scientific article

Oncologists' and cancer patients' views on whole-exome sequencing and incidental findings: results from the CanSeq study

scientific article published on 11 February 2016

One less thing to worry about: the shrinking spectrum of tumors in BRCA founder mutation carriers

scientific article published on 01 January 2004

Oral contraceptives and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers

scientific article

Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages

scientific article published on 06 April 2020

Outcome of triple negative breast cancer: comparison of sporadic and BRCA1-associated cancers

scientific article published on 18 May 2014

Outcome of unexpected adnexal neoplasia discovered during risk reduction salpingo-oophorectomy in women with germ-line BRCA1 or BRCA2 mutations

scientific article published on 12 December 2013

Ovarian and breast cancer risks associated with pathogenic variants in RAD51C and RAD51D

scientific article published on 28 February 2020

PALB2 mutations in familial breast and pancreatic cancer

scientific article published on June 2011

PARP inhibitors in the management of breast cancer: current data and future prospects

scientific article (publication date: 2015)

Parent decision-making around the genetic testing of children for germline TP53 mutations

scientific article published on 15 September 2014

Parenting Through Genetic Uncertainty: Themes in the Disclosure of Breast Cancer Risk Information to Children ⬇️

scientific article published on November 15, 2011

Pathologic Features and Immunophenotype of Estrogen Receptor–positive Breast Cancers in BRCA1 Mutation Carriers ⬇️

scientific article published on October 1, 2012

Pathologic findings in reduction mammoplasty specimens: a surrogate for the population prevalence of breast cancer and high-risk lesions

scientific article published on 20 September 2018

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

scientific article published on 5 December 2011

Patient Perceptions of Telephone vs. In-Person BRCA1/BRCA2 Genetic Counseling

scientific article published on 12 October 2015

Patients' Medical and Psychosocial Experiences After Detection of a CDH1 Variant With Multigene Panel Testing

scientific article published on 28 March 2019

Patterns of recurrence and metastasis in BRCA1/BRCA2-associated breast cancers

scientific article published on 03 October 2019

Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ

scientific article published on 13 September 2019

Physicians' experiences with BRCA1/2 testing in community settings

scientific article

Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants

scientific article published on 15 July 2020

Population-Wide Screening for Germline BRCA1 and BRCA2 Mutations: Too Much of a Good Thing?

scientific article published on 17 August 2015

Precancer Atlas to Drive Precision Prevention Trials.

scientific article

Precision Prevention and Early Detection of Cancer: Fundamental Principles

scientific article published on 15 June 2018

Pregnancy and risk of early breast cancer in carriers of BRCA1 and BRCA2

scientific article published in The Lancet

Premenopausal plasma osteoprotegerin and breast cancer risk: a case-control analysis nested within the Nurses' Health Study II

scientific article published on 10 April 2020

Pretest prediction of BRCA1 or BRCA2 mutation by risk counselors and the computer model BRCAPRO

scientific article published on 01 June 2002

Prevalence and correlates of mothers and fathers attending pretest cancer genetic counseling together

scientific article published on 09 July 2009

Prevalence and functional analysis of sequence variants in the ATR checkpoint mediator Claspin

scientific article

Prevalence and predictors of androgen receptor and programmed death-ligand 1 in BRCA1-associated and sporadic triple-negative breast cancer

scientific article

Prevalence and predictors of loss of wild type BRCA1 in estrogen receptor positive and negative BRCA1-associated breast cancers

scientific article

Prevalence of early onset colorectal cancer in 397 patients with classic Li-Fraumeni syndrome

scientific article published in January 2006

Prevalence of germline TP53 mutations in HER2+ breast cancer patients ⬇️

scientific article published on April 12, 2013

Prevalence of germline variants in inflammatory breast cancer

scientific article published on 01 April 2019

Prevalence of pathogenic germline cancer risk variants in high-risk urothelial carcinoma

scientific article published on 17 December 2019

Primary fallopian tube malignancies in BRCA-positive women undergoing surgery for ovarian cancer risk reduction

scientific article published on September 2007

Progesterone receptor variant increases ovarian cancer risk in BRCA1 and BRCA2 mutation carriers who were never exposed to oral contraceptives

scientific article published in October 2001

Progress in the management of gynecologic cancer: consensus summary statement

scientific article

Prophylactic oophorectomy in carriers of BRCA1 or BRCA2 mutations

scientific article

Prospective Study of the Efficacy of Breast Magnetic Resonance Imaging and Mammographic Screening in Survivors of Hodgkin Lymphoma ⬇️

scientific article published on April 22, 2013

Prospective evaluation of concurrent paclitaxel and radiation therapy after adjuvant doxorubicin and cyclophosphamide chemotherapy for Stage II or III breast cancer

scientific article published on 21 October 2005

Publisher Correction: Shared heritability and functional enrichment across six solid cancers

scientific article published on 23 September 2019

Quality or quantity in the management of hereditary ovarian cancer risk: Is it really a trade-off?

scientific article published on 12 September 2005

RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies

scientific article published on 16 October 2007

RASSF1A polymorphism A133S is associated with early onset breast cancer in BRCA1/2 mutation carriers

scientific article

RNF4-mediated polyubiquitination regulates the Fanconi anemia/BRCA pathway

scientific article

Randomized Noninferiority Trial of Telephone vs In-Person Genetic Counseling for Hereditary Breast and Ovarian Cancer: A 12-Month Follow-Up

scientific article published on 22 September 2017

Randomized Phase IIB Trial of the Lignan Secoisolariciresinol Diglucoside in Pre-menopausal Women at Increased Risk for Development of Breast Cancer

scientific article published on 20 April 2020

Randomized noninferiority trial of telephone versus in-person genetic counseling for hereditary breast and ovarian cancer.

scientific article published on 21 January 2014

Rapid progression of prostate cancer in men with a BRCA2 mutation

scientific article published on 24 June 2008

Reassessing risk models for atypical hyperplasia: age may not matter

scientific article published on 6 June 2017

Recommendations for follow-up care of individuals with an inherited predisposition to cancer. I. Hereditary nonpolyposis colon cancer. Cancer Genetics Studies Consortium

scientific article published on March 1997

Recommendations for follow-up care of individuals with an inherited predisposition to cancer. II. BRCA1 and BRCA2. Cancer Genetics Studies Consortium

scientific article

Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia

scientific article

Reply to S. Takamizawa et al

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Reproducibility of random periareolar fine needle aspiration in a multi-institutional Cancer and Leukemia Group B (CALGB) cross-sectional study

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Research issues affecting preoperative systemic therapy for operable breast cancer.

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Retinoblastoma protein expression and its predictors in triple-negative breast cancer

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Risk factors for a serous cancer precursor ("p53 signature") in women with inherited BRCA mutations

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Risk for breast cancer and management of unaffected individuals with non-BRCA hereditary breast cancer

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Risk-reducing salpingo-oophorectomy for the prevention of BRCA1- and BRCA2-associated breast and gynecologic cancer: a multicenter, prospective study

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Screening for germ line TP53 mutations in breast cancer patients

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Screening with whole-body magnetic resonance imaging in pediatric subjects with Li-Fraumeni syndrome: A single institution pilot study

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Sex ratio distortion in offspring of families with BRCA1 or BRCA2 mutant alleles: an ascertainment bias phenomenon?

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Shared heritability and functional enrichment across six solid cancers

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Sharing BRCA1/2 test results with first-degree relatives: factors predicting who women tell

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Spontaneous and therapeutic abortions and the risk of breast cancer among BRCA mutation carriers

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Statin Use and Breast Cancer Risk in the Nurses' Health Study

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Stumbling blocks on the path to personalized medicine in breast cancer: the case of PARP inhibitors for BRCA1/2-associated cancers

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Suggested application of HER2+ breast tumor phenotype for germline TP53 variant classification within ACMG/AMP guidelines

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Support needs and acceptability of psychological and peer consultation: attitudes of 108 women who had undergone or were considering prophylactic mastectomy

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TBCRC 031: Randomized Phase II Study of Neoadjuvant Cisplatin Versus Doxorubicin-Cyclophosphamide in Germline BRCA Carriers With HER2-Negative Breast Cancer (the INFORM trial)

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TBCRC 048: Phase II Study of Olaparib for Metastatic Breast Cancer and Mutations in Homologous Recombination-Related Genes

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TBCRC009: A Multicenter Phase II Clinical Trial of Platinum Monotherapy With Biomarker Assessment in Metastatic Triple-Negative Breast Cancer

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Talking to Children About Maternal BRCA1/2 Genetic Test Results: A Qualitative Study of Parental Perceptions and Advice ⬇️

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Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer

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Targeting the missing links for cancer therapy ⬇️

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Telomeric allelic imbalance indicates defective DNA repair and sensitivity to DNA-damaging agents

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Ten-Year Multi-Institutional Results of Breast-Conserving Surgery and Radiotherapy inBRCA1/2-Associated Stage I/II Breast Cancer

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The American Society of Clinical Oncology position on genetic testing: implications for health care providers: workshop no. 4

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The Effect of Atorvastatin on Breast Cancer Biomarkers in High-Risk Women

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The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer

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The Li-Fraumeni syndrome (LFS): a model for the initiation of p53 signatures in the distal Fallopian tube

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The association between germline BRCA2 variants and sensitivity to platinum-based chemotherapy among men with metastatic prostate cancer.

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The contribution of pathogenic variants in breast cancer susceptibility genes to familial breast cancer risk

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The feasibility of using natural language processing to extract clinical information from breast pathology reports ⬇️

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The fuzzy world of precision medicine: deliberations of a precision medicine tumor board

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The impact of a brief coping skills intervention on adherence to breast self-examination among first-degree relatives of newly diagnosed breast cancer patients

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The impact of tumor profiling approaches and genomic data strategies for cancer precision medicine

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The joint effect of smoking and AIB1 on breast cancer risk in BRCA1 mutation carriers

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The prevalence of germline BRCA1 and BRCA2 mutations in young women with breast cancer undergoing breast-conservation therapy

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The role of chemoprevention in modifying the risk of breast cancer in women with atypical breast lesions.

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The role of prevention in oncology practice: results from a 2004 survey of American Society of Clinical Oncology members

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The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome

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Time to incorporate germline multigene panel testing into breast and ovarian cancer patient care

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Towards Prevention of Breast Cancer: What Are the Clinical Challenges?

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Trans-counseling: A case series of transgender individuals at high risk for BRCA1 pathogenic variants

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Transcriptome-wide association study of breast cancer risk by estrogen-receptor status

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Transforming Cancer Prevention through Precision Medicine and Immune-oncology.

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Triple-Negative Breast Cancer Risk Genes Identified by Multigene Hereditary Cancer Panel Testing

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Triple-negative breast cancer: risk factors to potential targets

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Tubal ligation and risk of ovarian cancer in carriers of BRCA1 or BRCA2 mutations: a case-control study

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Underutilization of BRCA1/2 testing to guide breast cancer treatment: Black and Hispanic women particularly at risk ⬇️

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Unexpected Pathogenic RET p.V804M Variant Leads to the Clinical Diagnosis and Management of Medullary Thyroid Carcinoma

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Use of Endocrine Therapy for Breast Cancer Risk Reduction: ASCO Clinical Practice Guideline Update

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Use of pharmacologic interventions for breast cancer risk reduction: American Society of Clinical Oncology clinical practice guideline

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Use of risk-reducing surgeries in a prospective cohort of 1,499 BRCA1 and BRCA2 mutation carriers

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Using machine learning to parse breast pathology reports

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Uterine Cancer After Risk-Reducing Salpingo-oophorectomy Without Hysterectomy in Women With BRCA Mutations

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VEGF as a marker for outcome among advanced breast cancer patients receiving anti-VEGF therapy with bevacizumab and vinorelbine chemotherapy

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Whole-exome sequencing and clinical interpretation of formalin-fixed, paraffin-embedded tumor samples to guide precision cancer medicine

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Women's concerns about the emotional impact of awareness of heritable breast cancer risk and its implications for their children

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Young adult daughters of BRCA1/2 positive mothers: what do they know about hereditary cancer and how much do they worry?

scientific article published on 18 February 2013

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