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List of works by david filman

A Small Covalent Allosteric Inhibitor of Human Cytomegalovirus DNA Polymerase Subunit Interactions

scientific article published on 6 December 2016

A pseudo-cell based approach to efficient crystallographic refinement of viruses.

scientific article published in July 1996

A structural basis for allosteric control of DNA recombination by lambda integrase.

scientific article published on June 2005

Ab initio phasing of high-symmetry macromolecular complexes: successful phasing of authentic poliovirus data to 3.0 A resolution

scientific article

An Externalized Polypeptide Partitions between Two Distinct Sites on Genome-Released Poliovirus Particles ⬇️

scientific article published on July 20, 2011

An enzyme-substrate complex involved in bacterial cell wall biosynthesis

scientific article published on 01 August 1995

Architecture with a difference

scientific article published in Nature

Catching a Virus in the Act of RNA Release: a Novel Poliovirus Uncoating Intermediate Characterized by Cryo-Electron Microscopy

scientific article

Characterization of Poliovirus Neutralization Escape Mutants of Single-Domain Antibody Fragments (VHHs).

scientific article published on 26 May 2015

Cryo-EM reveals the structural basis of long-range electron transport in a cytochrome-based bacterial nanowire.

scientific article published on 19 June 2019

Cryo-EM structures reveal two distinct conformational states in a picornavirus cell entry intermediate

scientific article published on 30 September 2020

Cryo-Electron Microscopy Reconstruction Shows Poliovirus 135S Particles Poised for Membrane Interaction and RNA Release

scientific article

Cryo-electron Microscopy Structures of Expanded Poliovirus with VHHs Sample the Conformational Repertoire of the Expanded State

scientific article published on 16 November 2016

Crystal structure of a brominated RNA helix with four mismatched base pairs: An investigation into RNA conformational variability

scientific article

Crystal structure of the N-terminal domain of the group B streptococcus alpha C protein

scientific article published on 06 March 2005

Crystal structure of the cytomegalovirus DNA polymerase subunit UL44 in complex with the C terminus from the catalytic subunit. Differences in structure and function relative to unliganded UL44

scientific article published on 20 December 2005

Five of Five VHHs Neutralizing Poliovirus Bind the Receptor-Binding Site

scientific article published on 13 January 2016

Getting to and through the inner nuclear membrane during herpesvirus nuclear egress.

scientific article published on 10 January 2017

Identification of a glycosaminoglycan binding region of the alpha C protein that mediates entry of group B Streptococci into host cells

scientific article

Intracellular supravital stain delocalization as an assay for antibody-dependent complement-mediated cell damage ⬇️

scientific article published on January 1, 1975

Ligand-induced conformational changes in poliovirus-antiviral drug complexes

scientific article published on 01 September 1997

Mechanism of action and capsid-stabilizing properties of VHHs with an in vitro antipolioviral activity

scientific article

Molecular tectonic model of virus structural transitions: the putative cell entry states of poliovirus

scientific article

Nectin-like interactions between poliovirus and its receptor trigger conformational changes associated with cell entry

scientific article published on 28 January 2015

Poliovirus RNA is released from the capsid near a twofold symmetry axis

scientific article

RNA transfer from poliovirus 135S particles across membranes is mediated by long umbilical connectors

scientific article (publication date: April 2013)

Structural dynamics as a contributor to error-prone replication by an RNA-dependent RNA polymerase.

scientific article

Structural studies of poliovirus mutants that overcome receptor defects

scientific article

Structure of a herpesvirus nuclear egress complex subunit reveals an interaction groove that is essential for viral replication

scientific article published on 6 July 2015

Structure of the Fab-Labeled “Breathing” State of Native Poliovirus ⬇️

scientific article published on March 7, 2012

Structure of the complex between the Fab fragment of a neutralizing antibody for type 1 poliovirus and its viral epitope

scientific article

Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design

scientific article

The Crystal Structure of PF-8, the DNA Polymerase Accessory Subunit from Kaposi's Sarcoma-Associated Herpesvirus

scientific article

The antigenic structure of poliovirus.

scientific article

The crystal structure of Dps, a ferritin homolog that binds and protects DNA

scientific article published on April 1, 1998

The crystal structure of an unusual processivity factor, herpes simplex virus UL42, bound to the C terminus of its cognate polymerase

scientific article published in February 2000

The cytomegalovirus DNA polymerase subunit UL44 forms a C clamp-shaped dimer.

scientific article

Three-dimensional structure of poliovirus at 2.9 A resolution.

scientific article

Unexpected features and mechanism of heterodimer formation of a herpesvirus nuclear egress complex

scientific article

Use of MCSS to design small targeted libraries: application to picornavirus ligands.

scientific article

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