List of works by Chris Bakal

A Dynamical Framework for the All-or-None G1/S Transition.

scientific article published on 27 January 2016

A comprehensive model for the proliferation-quiescence decision in response to endogenous DNA damage in human cells.

scientific article published on 20 February 2018

A high-content RNAi screen reveals multiple roles for long noncoding RNAs in cell division

scientific article published on 15 April 2020

A screen for morphological complexity identifies regulators of switch-like transitions between discrete cell shapes

scientific article published on 9 June 2013

A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly.

scientific article published on 3 June 2015

AKT-mTOR signaling modulates the dynamics of IRE1 RNAse activity by regulating ER-mitochondria contacts.

scientific article published on 28 November 2017

ALPK1 hotspot mutation as a driver of human spiradenoma and spiradenocarcinoma

scientific article published on 17 May 2019

Accelerating Live Single-Cell Signalling Studies

scientific article

Apolar and polar transitions drive the conversion between amoeboid and mesenchymal shapes in melanoma cells.

scientific article

Cell cycle progression is an essential regulatory component of phospholipid metabolism and membrane homeostasis.

scientific article

Cell shape and the microenvironment regulate nuclear translocation of NF-κB in breast epithelial and tumor cells

scientific article

Chris Bakal: Look and learn. Interviewed by Caitlin Sedwick

scientific article published on November 2013

Ckap2 regulates aneuploidy, cell cycling, and cell death in a p53-dependent manner

scientific article

Clustering of Tir during enteropathogenic E. coli infection triggers calcium influx-dependent pyroptosis in intestinal epithelial cells

scientific article published on 30 December 2020

Cross-talk between Rho and Rac GTPases drives deterministic exploration of cellular shape space and morphological heterogeneity.

scientific article

DNA damage during S-phase mediates the proliferation-quiescence decision in the subsequent G1 via p21 expression.

scientific article

Differential RNAi screening provides insights into the rewiring of signalling networks during oxidative stress.

scientific article published in October 2012

Dynamic systems.

scientific article published on 30 January 2012

Erratum: A sensitised RNAi screen reveals a ch-TOG genetic interaction network required for spindle assembly

scientific article published on 31 July 2015

Genomic screening with RNAi: results and challenges

scientific article

How cells explore shape space: a quantitative statistical perspective of cellular morphogenesis

scientific article

Identification of clinically predictive metagenes that encode components of a network coupling cell shape to transcription by image-omics.

scientific article published on 18 November 2016

Inference of RhoGAP/GTPase regulation using single-cell morphological data from a combinatorial RNAi screen

scientific article

Mechanical and Systems Biology of Cancer

scientific article published on 17 July 2018

Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology-Genomic Integration Analysis

scientific article

Multiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion

scientific article (publication date: 25 January 2017)

Nanoneedle-Mediated Stimulation of Cell Mechanotransduction Machinery

scientific article published on 04 March 2019

NucliTrack: An integrated nuclei tracking application.

scientific article

PERK links the clock and protein stress in cancer

scientific article published in January 2018

Phosphorylation networks regulating JNK activity in diverse genetic backgrounds

scientific article published on October 2008

Proteomics profiling of interactome dynamics by colocalisation analysis (COLA).

scientific article published on 8 November 2016

Publisher Correction: AKT-mTOR signaling modulates the dynamics of IRE1 RNAse activity by regulating ER-mitochondria contacts.

scientific article published on 19 April 2018

Quantitative morphological signatures define local signaling networks regulating cell morphology.

scientific article

RNAi screens for Rho GTPase regulators of cell shape and YAP/TAZ localisation in triple negative breast cancer.

scientific article

RNAiCut: automated detection of significant genes from functional genomic screens.

scientific article published in July 2009

Realizing the promise of RNAi high throughput screening

scientific article published on April 2010

Signaling networks converge on TORC1-SREBP activity to promote endoplasmic reticulum homeostasis.

scientific article

Single-Cell Dynamics Determines Response to CDK4/6 Inhibition in Triple-Negative Breast Cancer

scientific article

Spatial Organization of Rho GTPase signaling by RhoGEF/RhoGAP proteins

scholarly article published 24 June 2018

Specificity of RNAi, LNA and CRISPRi as loss-of-function methods in transcriptional analysis

scientific article published on 01 July 2018

Squeezing through the microcirculation: survival adaptations of circulating tumour cells to seed metastasis

scientific article published on 01 December 2020

Survivin loss in thymocytes triggers p53-mediated growth arrest and p53-independent cell death

scientific article

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions

scientific article published on 23 March 2020

The MAGUK family protein CARD11 is essential for lymphocyte activation

scientific journal article

The Rho GTP exchange factor Lfc promotes spindle assembly in early mitosis

scientific article

The forces of cancer

scientific article published on 01 July 2019

The molecular adapter Carma1 controls entry of IkappaB kinase into the central immune synapse

scientific article published on November 2004

Visualizing cellular imaging data using PhenoPlot.

scientific article

Visualizing quantitative microscopy data: History and challenges

scientific article

WDR5, BRCA1, and BARD1 Co-regulate the DNA Damage Response and Modulate the Mesenchymal-to-Epithelial Transition during Early Reprogramming

scientific article published on 14 March 2019

Paulina is supported by:

About Paulina

Help