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List of works by Hideaki Yano

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Hetero-oligomerization of CCR2, CCR5, and CXCR4 and the protean effects of "selective" antagonists.

scientific article published on 15 September 2009
A mechanism for intracellular release of Na+ by neurotransmitter/sodium symporters

scientific article
State-dependent conformations of the translocation pathway in the tyrosine transporter Tyt1, a novel neurotransmitter:sodium symporter from Fusobacterium nucleatum.

scientific article published on 23 June 2006
Functional selectivity of allosteric interactions within G protein-coupled receptor oligomers: the dopamine D1-D3 receptor heterotetramer.

scientific article
Evidence against dopamine D1/D2 receptor heteromers

scientific article
The membrane raft protein Flotillin-1 is essential in dopamine neurons for amphetamine-induced behavior in Drosophila.

scientific article published on 19 June 2012
Dopamine receptor activation increases HIV entry into primary human macrophages

scientific article
Evidence for Noncanonical Neurotransmitter Activation: Norepinephrine as a Dopamine D2-Like Receptor Agonist

scientific article published on 3 February 2016
The sigma-1 receptor modulates dopamine transporter conformation and cocaine binding and may thereby potentiate cocaine self-administration in rats

scientific article published on 11 May 2017
Novel and High Affinity 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues as Atypical Dopamine Transporter Inhibitors

scientific article
Novel Bivalent Ligands Based on the Sumanirole Pharmacophore Reveal Dopamine D2 Receptor (D2R) Biased Agonism

scientific article published on 16 March 2017
Toward Understanding the Structural Basis of Partial Agonism at the Dopamine D3 Receptor

scientific article
HIV, Tat and dopamine transmission.

scientific article published on 27 April 2017
Pharmacological profiling of sigma 1 receptor ligands by novel receptor homomer assays.

scientific article
Gs- versus Golf-dependent functional selectivity mediated by the dopamine D1 receptor.

scientific article published on 5 February 2018
Novel and Potent Dopamine D Receptor Go-Protein Biased Agonists

article
Synthesis and biological evaluation of a novel series of heterobivalent muscarinic ligands based on xanomeline and 1-[3-(4-butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1).

scientific article published on 16 October 2014
1-[3-(4-Butylpiperidin-1-yl)propyl]-1,2,3,4-tetrahydroquinolin-2-one (77-LH-28-1) as a Model for the Rational Design of a Novel Class of Brain Penetrant Ligands with High Affinity and Selectivity for Dopamine D4 Receptor.

scientific article published on 28 March 2018
A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity

scientific article published on 04 February 2020
Luciferase complementation based-detection of G-protein-coupled receptor activity

scientific article published on 01 July 2018
Assessment of left ventricular systolic function using contrast two-dimensional echocardiography with a high-frequency transducer in the awake murine model of myocardial infarction

scientific article published on 01 November 2001
Revisiting the Functional Role of Dopamine D Receptor Gene Polymorphisms: Heteromerization-Dependent Gain of Function of the D Receptor Variant

article
High-Frequency Activation of Nucleus Accumbens D1-MSNs Drives Excitatory Potentiation on D2-MSNs

scientific article published on 17 June 2019
α2A- and α2C-Adrenoceptors as Potential Targets for Dopamine and Dopamine Receptor Ligands

scientific article published on 18 March 2018
Development of novel biosensors to study receptor-mediated activation of the G-protein α subunits Gs and Golf.

scientific article published on 17 October 2017
The Effects of Terminal Tagging on Homomeric Interactions of the Sigma 1 Receptor

scientific article published on 19 December 2019
A Novel Bromine-Containing Paroxetine Analogue Provides Mechanistic Clues for Binding Ambiguity at the Central Primary Binding Site of the Serotonin Transporter

scientific article published on 22 August 2019
The Glu102 mutation disrupts higher-order oligomerization of the sigma 1 receptor

scientific article published on 07 January 2020
Bioluminescence Resonance Energy Transfer Assay to Characterize Gi-Like G Protein Subtype-Dependent Functional Selectivity.

scientific article

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