Search filters

List of works by Helen M Prior

A multi-site comparison of in vivo safety pharmacology studies conducted to support ICH S7A & B regulatory submissions.

scientific article published on 09 May 2013

An Analysis of the Relationship Between Preclinical and Clinical QT Interval-Related Data

scientific article

Biomarkers of drug-induced vascular injury.

scientific article

Functions of large conductance Ca2+‐activated (BKCa), delayed rectifier (KV) and background K+ channels in the control of membrane potential in rabbit renal arcuate artery ⬇️

scientific article published on August 15, 1998

Further investigations into the mechanism of the antihypertensive activity of the angiotensin AT1 receptor antagonist, GR138950.

scientific article published on June 1996

Incorporation of capillary microsampling into whole body plethysmography and modified Irwin safety pharmacology studies in rats

scientific article

Integration of Consortia Recommendations for Justification of Animal Use Within Current and Future Drug Development Paradigms

scientific article published on 20 June 2019

Neurofunctional test batteries in safety pharmacology - Current and emerging considerations for the drug development process

scientific article published on 22 June 2019

Non-invasive telemetric electrocardiogram assessment in conscious beagle dogs.

scientific article

Opportunities for use of one species for longer-term toxicology testing during drug development: A cross-industry evaluation

scientific article published on 29 February 2020

Opportunities to Apply the 3Rs in Safety Assessment Programs

scientific article published on December 2016

Predicting the safety of medicines in pregnancy: A workshop report

scientific article published on 29 February 2020

Provision of food and water in rodent whole body plethysmography safety pharmacology respiratory studies - Impact on animal welfare and data quality.

scientific article published on 02 August 2017

Refinement of the charcoal meal study by reduction of the fasting period.

scientific article published in May 2012

Reflections on the progress towards non-animal methods for acute toxicity testing of chemicals

scientific article published on 20 December 2018

Role of K+ channels in A2A adenosine receptor-mediated dilation of the pressurized renal arcuate artery.

scientific article published on January 1999

Safety pharmacology--a progressive approach

scientific article published on 01 June 2002

Social housing of non-rodents during cardiovascular recordings in safety pharmacology and toxicology studies

scientific article published on 30 March 2016

Social-housing and use of double-decker cages in rat telemetry studies

scientific article published on 16 February 2019

The contribution of VEGF signalling to fostamatinib-induced blood pressure elevation

scientific article published on May 2014

The effects of pharmacological modulation of KATP on the guinea-pig isolated diaphragm.

scientific article

The functional observational battery and modified Irwin test as global neurobehavioral assessments in the rat: Pharmacological validation data and a comparison of methods

scientific article published on 27 May 2019

The use of human tissue in safety assessment

scientific article published on 09 May 2018

Paulina is supported by:

About Paulina

Help