Search filters

List of works by Gaudenz Danuser

3D flow field estimation and assessment for live cell fluorescence microscopy

scientific article published on 01 March 2020

A Novel Approach To Produce Biologically Relevant Chemical Patterns at the Nanometer Scale: Selective Molecular Assembly Patterning Combined with Colloidal Lithography

A RhoC biosensor reveals differences in the activation kinetics of RhoA and RhoC in migrating cells

scientific article

A growth factor-induced, spatially organizing cytoskeletal module enables rapid and persistent fibroblast migration

scientific article

A method for measuring the distribution of the shortest telomeres in cells and tissues

scientific article published on 7 November 2017

A non-canonical role for dynamin-1 in regulating early stages of clathrin-mediated endocytosis in non-neuronal cells

A noncanonical role for dynamin-1 in regulating early stages of clathrin-mediated endocytosis in non-neuronal cells.

scientific article published on 18 April 2018

Actin-Membrane Release Initiates Cell Protrusions

scientific article published on 10 December 2020

Actin-myosin network reorganization breaks symmetry at the cell rear to spontaneously initiate polarized cell motility

scientific article

Advances in analysis of low signal-to-noise images link dynamin and AP2 to the functions of an endocytic checkpoint

scientific article published on 25 July 2013

Altered metabolic requirements in cancer cell migration and metastasis.

scientific article published in June 2012

An image-based assay to quantify changes in proliferation and viability upon drug treatment in 3D microenvironments

scientific article published on 28 May 2019

Analysis of microtubule dynamic instability using a plus-end growth marker

scientific article

Antagonism between the microtubule plus-end-tracking proteins Msps and CLASP during Abl kinase-mediated axon pathfinding

Architectural dynamics of the meiotic spindle revealed by single-fluorophore imaging

scientific article

Augmin accumulation on long-lived microtubules drives amplification and kinetochore-directed growth

scientific article published on 21 May 2019

Automated profiling of growth cone heterogeneity defines relations between morphology and motility

scientific article published on 06 December 2018

Automated screening of microtubule growth dynamics identifies MARK2 as a regulator of leading edge microtubules downstream of Rac1 in migrating cells

scientific article

Automatic fluorescent tag detection in 3D with super-resolution: application to the analysis of chromosome movement.

scientific article published in October 2002

Automatic fluorescent tag localization II: Improvement in super-resolution by relative tracking.

scientific article

Cargo and dynamin regulate clathrin-coated pit maturation.

scientific article

Cargo- and adaptor-specific mechanisms regulate clathrin-mediated endocytosis.

scientific article

Cell forces meet cell metabolism

scientific article published in May 2017

Cell migration without a lamellipodium: translation of actin dynamics into cell movement mediated by tropomyosin

scientific article

Chemically patterned, metal-oxide-based surfaces produced by photolithographic techniques for studying protein- and cell-interactions. II: Protein adsorption and early cell interactions

scientific article published on 01 March 2003

Co-immunoprecipitation and semi-quantitative immunoblotting for the analysis of protein-protein interactions

scientific article published on 17 September 2021

Cofilin activity downstream of Pak1 regulates cell protrusion efficiency by organizing lamellipodium and lamella actin networks

scientific article

Comparative autoregressive moving average analysis of kinetochore microtubule dynamics in yeast.

scientific article

Competition for actin between two distinct F-actin networks defines a bistable switch for cell polarization.

scientific article

Computational Analysis of F-Actin Turnover in Cortical Actin Meshworks Using Fluorescent Speckle Microscopy ⬇️

scientific article published on May 1, 2003

Computational image analysis of cellular dynamics: a case study based on particle tracking

scientific article published on December 2009

Computational processing and analysis of dynamic fluorescence image data

scientific article

Computer vision in cell biology

scientific article published on 01 November 2011

Coordination of Rho GTPase activities during cell protrusion

scientific article

Coordination of actin filament and microtubule dynamics during neurite outgrowth

scientific article

Correction: Mapping the dynamics of force transduction at cell-cell junctions of epithelial clusters

scientific article published in January 2015

Coupling the dynamics of two actin networks--new views on the mechanics of cell protrusion.

scientific article published in December 2005

Cytoskeletal control of CD36 diffusion promotes its receptor and signaling function

scientific article

DASC, a sensitive classifier for measuring discrete early stages in clathrin-mediated endocytosis

scientific article published on 30 April 2020

Deconvolution-free Subcellular Imaging with Axially Swept Light Sheet Microscopy

scientific article published on June 2015

Decoupling global biases and local interactions between cell biological variables

scientific article published on 13 March 2017

Decoupling global biases and local interactions between cell biological variables

article

Delivery of membrane impermeable cargo into CHO cells by peptide nanoparticles targeted by a protein corona

scientific article

Differential KrasV12 protein levels control a switch regulating lung cancer cell morphology and motility

scientific article published on 20 September 2016

Differential transmission of actin motion within focal adhesions

scientific article

Direct Microtubule-Binding by Myosin-10 Orients Centrosomes toward Retraction Fibers and Subcortical Actin Clouds

scientific article

Directly probing the mechanical properties of the spindle and its matrix

scientific article

Discovery of functional interactions among actin regulators by analysis of image fluctuations in an unperturbed motile cell system

scientific article published in May 2018

Distinct ECM mechanosensing pathways regulate microtubule dynamics to control endothelial cell branching morphogenesis

scientific article

Diverse roles of guanine nucleotide exchange factors in regulating collective cell migration

scientific article

ERK reinforces actin polymerization to power persistent edge protrusion during motility.

scientific article

ERK-MAPK drives lamellipodia protrusion by activating the WAVE2 regulatory complex

scientific article

Endocytic accessory proteins are functionally distinguished by their differential effects on the maturation of clathrin-coated pits

scientific article

Enhanced Dendritic Actin Network Formation in Extended Lamellipodia Drives Proliferation in Growth-Challenged Rac1P29S Melanoma Cells

scientific article published on 01 May 2019

Estimation of the fraction of COVID-19 infected people in U.S. states and countries worldwide

scientific article published in 2021

FRET binding antenna reports spatiotemporal dynamics of GDI-Cdc42 GTPase interactions

scientific article

FRET or no FRET: a quantitative comparison

scientific article published on June 2003

Filopodial actin bundles are not necessary for microtubule advance into the peripheral domain of Aplysia neuronal growth cones

scientific article published on 18 November 2007

Fluctuation analysis of activity biosensor images for the study of information flow in signaling pathways.

scientific article published on January 2013

Fluctuations of intracellular forces during cell protrusion

scientific article

Functional characterization of 67 endocytic accessory proteins using multiparametric quantitative analysis of CCP dynamics

scientific article published on 30 November 2020

Functional hierarchy of redundant actin assembly factors revealed by fine-grained registration of intrinsic image fluctuations

scientific article

GSK3beta phosphorylation modulates CLASP-microtubule association and lamella microtubule attachment.

scientific article published on 16 March 2009

Gaudenz Danuser: the symphony of the cell. Interview by Caitlin Sedwick

scientific article published on November 2012

Global and local regulation of clathrin-coated pit dynamics detected on patterned substrates.

scientific article published on August 2009

Growth cone-specific functions of XMAP215 in restricting microtubule dynamics and promoting axonal outgrowth

scientific article

High refractive index silicone gels for simultaneous total internal reflection fluorescence and traction force microscopy of adherent cells

scientific article

Hotspots organize clathrin-mediated endocytosis by efficient recruitment and retention of nucleating resources.

scientific article

Imaging and modeling the dynamics of clathrin-mediated endocytosis

scientific article

Imaging assay to probe the role of telomere length shortening on telomere-gene interactions in single cells

scientific article published in March 2021

Imaging the coordination of multiple signalling activities in living cells

scientific article published on 21 October 2011

In vivo cell-cycle profiling in xenograft tumors by quantitative intravital microscopy

scientific article

Inhibition of epithelial cell migration and Src/FAK signaling by SIRT3

scientific article published on 18 June 2018

Integrin-dependent actomyosin contraction regulates epithelial cell scattering.

scientific article

Interpretable deep learning uncovers cellular properties in label-free live cell images that are predictive of highly metastatic melanoma

scientific article published on 01 June 2021

Kinesin 5-independent poleward flux of kinetochore microtubules in PtK1 cells

scientific article

Kinetochore alignment within the metaphase plate is regulated by centromere stiffness and microtubule depolymerases

scientific article

LOVTRAP: an optogenetic system for photoinduced protein dissociation

scientific article

Light-sheet microscopy of cleared tissues with isotropic, subcellular resolution

scientific article published on 31 October 2019

Linking data to models: data regression

scientific article published on 27 September 2006

Live cell imaging of F-actin dynamics via Fluorescent Speckle Microscopy (FSM).

scientific article published on 5 August 2009

Local clustering of transferrin receptors promotes clathrin-coated pit initiation. ⬇️

scientific article

Locomotion of fish epidermal keratocytes on spatially selective adhesion patterns

scientific article published in November 2007

Manipulation of endogenous kinase activity in living cells using photoswitchable inhibitory peptides

scientific article published on 13 June 2014

Mapping the dynamics of force transduction at cell-cell junctions of epithelial clusters.

scientific article

Mathematical modeling of eukaryotic cell migration: insights beyond experiments

scientific article

Measurement of the strain field in a micrometer-sized region at a notch tip

Measuring the hierarchy of molecular events during clathrin-mediated endocytosis

scientific article

Mechanical feedback through E-cadherin promotes direction sensing during collective cell migration

scientific article

Mechanical regulation of glycolysis via cytoskeleton architecture

scientific article published on 12 February 2020

Mechanism of lateral movement of filopodia and radial actin bundles across neuronal growth cones

scientific article

Microcontact printing of novel co-polymers in combination with proteins for cell-biological applications.

scientific article published on May 2003

Microtubule-dependent transport and dynamics of vimentin intermediate filaments

scientific article

Modeling of protrusion phenotypes driven by the actin-membrane interaction

scientific article

Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila

scientific article

Morphodynamic profiling of protrusion phenotypes.

scientific article

Multiparametric analysis of CLASP-interacting protein functions during interphase microtubule dynamics

scientific article

Multiplexed Exchange-PAINT imaging reveals ligand-dependent EGFR and Met interactions in the plasma membrane

scientific article published on 22 September 2017

Multiplexed GTPase and GEF biosensor imaging enables network connectivity analysis

scientific article published on 18 May 2020

Myosin II activity facilitates microtubule bundling in the neuronal growth cone neck

scientific article

Myosin II contributes to cell-scale actin network treadmilling through network disassembly

scientific article

Myosin II controls cellular branching morphogenesis and migration in three dimensions by minimizing cell-surface curvature

scientific article

New directions for fluorescent speckle microscopy.

scientific article

Nuclear positioning facilitates amoeboid migration along the path of least resistance

scientific article published on 03 April 2019

Op18 reveals the contribution of nonkinetochore microtubules to the dynamic organization of the vertebrate meiotic spindle

scientific article

Optimal-Flow Minimum-Cost Correspondence Assignment in Particle Flow Tracking

scientific article

Ovarian cancer spheroids use myosin-generated force to clear the mesothelium

scientific article

Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration

scientific article published on June 2011

Periodic patterns of actin turnover in lamellipodia and lamellae of migrating epithelial cells analyzed by quantitative Fluorescent Speckle Microscopy.

scientific article

Phosphatidic acid plays a regulatory role in clathrin-mediated endocytosis

scientific article

Phosphatidylinositol-(4,5)-bisphosphate regulates clathrin-coated pit initiation, stabilization, and size

scientific article

Photogrammetric calibration of a stereo light microscope.

scientific article

Piecewise-Stationary Motion Modeling and Iterative Smoothing to Track Heterogeneous Particle Motions in Dense Environments.

scientific article published in November 2017

Positional stability of single double-strand breaks in mammalian cells

scientific article published on 7 May 2007

Pre-complexation of talin and vinculin without tension is required for efficient nascent adhesion maturation

scientific article published on 30 March 2021

Probing f-actin flow by tracking shape fluctuations of radial bundles in lamellipodia of motile cells.

scientific article

Probing intracellular force distributions by high-resolution live cell imaging and inverse dynamics

scientific article published in January 2007

Profiling cellular morphodynamics by spatiotemporal spectrum decomposition

scholarly article by Xiao Ma published in August 2018

Protein kinase A governs a RhoA-RhoGDI protrusion-retraction pacemaker in migrating cells.

scientific article

Protrusion and actin assembly are coupled to the organization of lamellar contractile structures

scientific article published on 18 April 2010

Quantifying Modes of 3D Cell Migration

scientific article

Quantitative Fluorescent Speckle Microscopy of the Actin Cytoskeleton in Migrating Cells

Quantitative Multiscale Cell Imaging in Controlled 3D Microenvironments

scientific article published on February 2016

Quantitative fluorescent speckle microscopy (QFSM) to measure actin dynamics.

scientific article published on October 2012

Quantitative fluorescent speckle microscopy of cytoskeleton dynamics

scientific article

Quantitative fluorescent speckle microscopy: where it came from and where it is going.

scientific article

Quantitative image analysis identifies pVHL as a key regulator of microtubule dynamic instability

scientific article

Quantitative imaging of epithelial cell scattering identifies specific inhibitors of cell motility and cell-cell dissociation.

scientific article

Recovery, visualization, and analysis of actin and tubulin polymer flow in live cells: a fluorescent speckle microscopy study

scientific article

Regional variation of microtubule flux reveals microtubule organization in the metaphase meiotic spindle

scientific article

Regulation of Clathrin-Mediated Endocytosis.

scientific article published on 16 April 2018

Reply to "Acquisition frame rate affects microtubule plus-end tracking analysis".

scientific article published in March 2014

Robust and automated detection of subcellular morphological motifs in 3D microscopy images

scientific article published on 09 September 2019

Robust single-particle tracking in live-cell time-lapse sequences

scientific article

S. cerevisiae chromosomes biorient via gradual resolution of syntely between S phase and anaphase

scientific article published on August 2013

SH3BP4 promotes neuropilin-1 and α5-integrin endocytosis and is inhibited by Akt

scientific article published on 19 April 2021

Scale integration: the structure and dynamics of macromolecular assemblies, cells and tissues ⬇️

scientific article published on February 16, 2012

Seeds of Locally Aligned Motion and Stress Coordinate a Collective Cell Migration

scientific article

Selective Molecular Assembly Patterning: A New Approach to Micro- and Nanochemical Patterning of Surfaces for Biological Applications

Signal analysis of total internal reflection fluorescent speckle microscopy (TIR-FSM) and wide-field epi-fluorescence FSM of the actin cytoskeleton and focal adhesions in living cells.

scientific article published in November 2004

Simultaneous mapping of filamentous actin flow and turnover in migrating cells by quantitative fluorescent speckle microscopy

scholarly article

Single muscle fiber contraction is dictated by inter-sarcomere dynamics

scientific article published in May 2002

Spatiotemporal dynamics of GEF-H1 activation controlled by microtubule- and Src-mediated pathways

scientific article published on 16 August 2019

Spindle fusion requires dynein-mediated sliding of oppositely oriented microtubules

scientific article

Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility.

scientific article

Super-resolution microscopy using normal flow decoding and geometric constraints.

scientific article published in November 2001

Surface modification of PLGA microspheres.

scientific article

TRA-1-60-positive/CD45low cells found in the peripheral blood of prostate cancer patients with metastatic disease - A proof-of-concept study

scientific article published on 24 January 2020

Testing the lamella hypothesis: the next steps on the agenda

scientific article published on June 2009

Tracking differential interference contrast diffraction line images with nanometre sensitivity.

scientific article

Tracking quasi-stationary flow of weak fluorescent signals by adaptive multi-frame correlation.

scientific article published in December 2005

Tracking retrograde flow in keratocytes: news from the front

scientific article

Traction microscopy to identify force modulation in subresolution adhesions

scientific article published on June 2015

Traction stress in focal adhesions correlates biphasically with actin retrograde flow speed

scientific article

Tumor suppressor NF2/Merlin is a microtubule stabilizer

scientific article

Two distinct actin networks drive the protrusion of migrating cells

scientific article

Using fluctuation analysis to establish causal relations between cellular events without experimental perturbation

scientific article

Vimentin Intermediate Filaments Template Microtubule Networks to Enhance Persistence in Cell Polarity and Directed Migration

scientific article published on 01 November 2016

Vimentin Intermediate Filaments Template Microtubule Networks to Enhance Persistence in Cell Polarity and Directed Migration.

scientific article

Vimentin fibers orient traction stress

scientific article published on 2 May 2017

Vinculin-actin interaction couples actin retrograde flow to focal adhesions, but is dispensable for focal adhesion growth.

scientific article

Visualizing and quantifying adhesive signals

scientific article published on 27 June 2008

What's wrong with correlative experiments?

scientific article

Yeast kinetochore microtubule dynamics analyzed by high-resolution three-dimensional microscopy

scientific article

plusTipTracker: Quantitative image analysis software for the measurement of microtubule dynamics

scientific article published on 29 July 2011

Paulina is supported by:

About Paulina

Help