List of works - Prokopios Magiatis

"Pistacia lentiscus L." reduces the infarct size in normal fed anesthetized rabbits and possess antiatheromatic and hypolipidemic activity in cholesterol fed rabbits

scientific article

1H NMR-based metabonomics for the classification of Greek wines according to variety, region, and vintage. Comparison with HPLC data

scientific article

2,2-Dimethyl-2H-anthra[2,3-b]pyran-6,11-diones: a new class of cytotoxic compounds

scientific article published on 01 March 2001

2,3-cis-2R,3R-(-)-epiafzelechin-3-O-p-coumarate, a novel flavan-3-ol isolated from Fallopia convolvulus seed, is an estrogen receptor agonist in human cell lines.

scientific article

3'-Substituted 7-halogenoindirubins, a new class of cell death inducing agents.

scientific article published on July 2006

6-Br-5methylindirubin-3'oxime (5-Me-6-BIO) targeting the leishmanial glycogen synthase kinase-3 (GSK-3) short form affects cell-cycle progression and induces apoptosis-like death: exploitation of GSK-3 for treating leishmaniasis

scientific article published on 13 May 2009

6-Bromoindirubin-3'-oxime inhibits JAK/STAT3 signaling and induces apoptosis of human melanoma cells.

scientific article

A Biomimetic, One-Step Transformation of Simple Indolic Compounds to Malassezia-Related Alkaloids with High AhR Potency and Efficacy

scientific article published on 07 November 2019

A Method for the Rapid Measurement of Alkylresorcinols in Flour, Bread and Related Products Based on 1H qNMR

scientific article published on 31 July 2020

A new process for the management of olive oil mill waste water and recovery of natural antioxidants

scientific article

A novel 7-bromoindirubin with potent anticancer activity suppresses survival of human melanoma cells associated with inhibition of STAT3 and Akt signaling ⬇️

scientific article published on August 16, 2012

A traditional Chinese remedy points to a natural skin habitat: indirubin (indigo naturalis) for psoriasis and the Malassezia metabolome

scientific article published on 04 July 2018

Activity of grape extracts from Greek varieties of Vitis vinifera against mutagenicity induced by bleomycin and hydrogen peroxide in Salmonella typhimurium strain TA102.

scientific article published on 28 August 2006

AhR ligands, malassezin, and indolo[3,2-b]carbazole are selectively produced by Malassezia furfur strains isolated from seborrheic dermatitis.

scientific article published on 24 January 2008

Alkaloids from Sarcomelicope megistophylla

scientific article published on 14 November 2006

An Integrated Computational Approach to the Phenomenon of Potent and Selective Inhibition of Aurora Kinases B and C by a Series of 7-Substituted Indirubins

scientific article published on 01 August 2007

Asymmetric synthesis of gamma-keto-delta-lactam derivatives: application to the synthesis of a conformationally constrained surrogate of Ala-Ser dipeptide.

scientific article published in November 2001

Biotechnological Approaches on Two High CBD and CBG <i>Cannabis sativa</i> L. (Cannabaceae) Varieties: In Vitro Regeneration and Phytochemical Consistency Evaluation of Micropropagated Plants Using Quantitative <sup>1</sup>H-NMR

scientific article published on 15 December 2020

Biotransformation of the flavonoid tiliroside to 7-methylether tiliroside: bioactivity of this metabolite and of its acetylated derivative

scientific article published on 01 July 1997

Chemical investigation and antimicrobial properties of mastic water and its major constituents.

scientific article

Coelobillardin, an iridoid glucoside dimer from Coelospermum billardieri.

scientific article published in June 2002

Composition and enantiomeric analysis of the essential oil of the fruits and the leaves of Pistacia vera from Greece

scientific article published on 30 June 2007

Could Malassezia yeasts be implicated in skin carcinogenesis through the production of aryl-hydrocarbon receptor ligands?

scientific article published on 27 March 2011

Coumarins from Peucedanum luxurians

scientific article published on 24 May 2007

Cultivar influence on variability in olive oil phenolic profiles determined through an extensive germplasm survey

scientific article published on 04 June 2018

Detection, Isolation, and ¹H NMR Quantitation of the Nitrile Glycoside Sarmentosin from a Bryophyllum pinnatum Hydro-Ethanolic Extract

scientific article published in 2021

Direct Analysis of Free and Sulfite-Bound Carbonyl Compounds in Wine by Two-Dimensional Quantitative Proton and Carbon Nuclear Magnetic Resonance Spectroscopy.

scientific article published on 8 September 2015

Direct measurement of oleocanthal and oleacein levels in olive oil by quantitative (1)H NMR. Establishment of a new index for the characterization of extra virgin olive oils.

scientific article

Effect of cold temperature on the composition of different lipid classes of the foodborne pathogen Listeria monocytogenes: focus on neutral lipids

scientific article published on 01 April 2006

Effect of the form of the sesame-based diet on the absorption of lignans.

scientific article published on 23 April 2008

Estrogenic activity of phenylpropanoids from Sarcomelicope megistophylla and structure determination of a new norneolignan

scientific article published on 01 June 2003

GSK-3-selective inhibitors derived from Tyrian purple indirubins

scientific article

Hemi-synthesis and biological activity of new analogues of podophyllotoxin.

scientific article

Homarine, a common metabolite in edible Mediterranean molluscs: occurrence, spectral data and revision of a related structure.

scientific article

Hydrolyzable tannins, the active constituents of three Greek Cytinus taxa against several tumor cell lines ⬇️

scientific article published on 01 June 2001

Hyperjovinols A and B: Two new phloroglucinol derivatives from Hypericum jovis with antioxidant activity in cell cultures.

scientific article

Identification of black pine (Pinus nigra Arn.) heartwood as a rich source of bioactive stilbenes by qNMR.

scientific article published on 14 October 2016

Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins

scientific article published on May 2004

Induction of discrete apoptotic pathways by bromo-substituted indirubin derivatives in invasive breast cancer cells ⬇️

scientific article published on July 20, 2012

Influence of Harvest Time and Malaxation Conditions on the Concentration of Individual Phenols in Extra Virgin Olive Oil Related to Its Healthy Properties

scientific article published on 24 May 2020

Isolation of megaritolactones and other bioactive metabolites from 'megaritiki' table olives and debittering water.

scientific article

Malassezia yeasts produce a collection of exceptionally potent activators of the Ah (dioxin) receptor detected in diseased human skin

scientific article published on 28 February 2013

Malassezia-derived indoles activate the aryl hydrocarbon receptor and inhibit Toll-like receptor-induced maturation in monocyte-derived dendritic cells

scientific article published on 19 July 2012

Measuring protection of aromatic wine thiols from oxidation by competitive reactions vs wine preservatives with ortho-quinones

scientific article published on 30 April 2014

Natural and synthetic 2,2-dimethylpyranocoumarins with antibacterial activity.

scientific article

New alkylresorcinols from a lipophilic extract of Urginea indica L. bulbs showing experimental trauma healing activity.

scientific article published on 24 December 2014

New lignans from the perisperm of Sesamum indicum

scientific article published on 01 October 2006

Novel Inverse Binding Mode of Indirubin Derivatives Yields Improved Selectivity for DYRK Kinases

scientific article published on November 2012

Oil quality parameters and quantitative measurement of major secoiridoid derivatives in Neb Jmel olive oil from various Tunisian origins using qNMR.

scientific article

Oleacein Attenuates the Pathogenesis of Experimental Autoimmune Encephalomyelitis through Both Antioxidant and Anti-Inflammatory Effects

scientific article published on 21 November 2020

Oleocanthal-rich extra virgin olive oil demonstrates acute anti-platelet effects in healthy men in a randomized trial

scientific article published on 03 July 2017

Oleocanthalic Acid, a Chemical Marker of Olive Oil Aging and Exposure to a High Storage Temperature with Potential Neuroprotective Activity

scientific article published on 03 July 2018

Oleuropein as a bioactive constituent added in milk and yogurt.

scientific article

Oral administration of chios mastic gum or extracts in mice: quantification of triterpenic acids by liquid chromatography-tandem mass spectrometry

scientific article published on 25 August 2011

Photoreactivity of indirubin derivatives.

scientific article

Phytochemical analysis of young fustic (Cotinus coggygria heartwood) and identification of isolated colourants in historical textiles.

scientific article

Pityriazepin and other potent AhR ligands isolated from Malassezia furfur yeast

scientific article published on 24 February 2015

Quality profile determination of Chios mastic gum essential oil and detection of adulteration in mastic oil products with the application of chiral and non-chiral GC-MS analysis.

scientific article

Quantitative measurement of major secoiridoid derivatives in olive oil using qNMR. Proof of the artificial formation of aldehydic oleuropein and ligstroside aglycon isomers

scientific article published on 13 January 2014

Quantitative method for determination of oleocanthal and oleacein in virgin olive oils by liquid chromatography-tandem mass spectrometry

scientific article published on 24 September 2016

S-(E)-Elenolide: a new constituent of extra virgin olive oil

scientific article published on 30 May 2019

Samioside, a new phenylethanoid glycoside with free-radical scavenging and antimicrobial activities from Phlomis samia.

scientific article published in August 2001

Selective amination of secoiridoid glycosides to give monomeric pyridine, dimeric pyridine, and naphthyridine alkaloids.

scientific article published in January 2001

Sesamolinol glucoside, disaminyl ether, and other lignans from sesame seeds

scientific article published on 28 December 2011

Soluble 3',6-substituted indirubins with enhanced selectivity toward glycogen synthase kinase -3 alter circadian period

scientific article published on 25 September 2008

Stability of oleuropein in the human proximal gut.

scientific article published in February 2009

Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases

scientific article published in February 2004

Structure elucidation and chromatographic identification of anthraquinone components of cochineal (Dactylopius coccus) detected in historical objects.

scientific article published on 05 October 2013

Synthesis and antiproliferative activity of 7-azaindirubin-3'-oxime, a 7-aza isostere of the natural indirubin pharmacophore.

scientific article published in December 2009

Synthesis and antiproliferative activity of retroetoposide.

scientific article published on November 2003

Synthesis and biological activity of esters in the trans-1,2-dihydroxy-1,2-dihydroacronycine series

scientific article published on 01 February 1998

Synthesis and biological evaluation of novel daunorubicin-estrogen conjugates.

scientific article

Synthesis and cytotoxic activity of pyranocoumarins of the seselin and xanthyletin series

scientific article published on 01 August 1998

Synthesis of (R)-dihydropyridones as key intermediates for an efficient access to piperidine alkaloids

scientific article published on 10 April 2007

Synthesis of novel nitro-substituted triaryl pyrazole derivatives as potential estrogen receptor ligands.

scientific article published on 2 July 2007

The structure of sarcomejine: an application of long-range (1)H-(15)N correlation at natural abundance

scientific article published on 01 July 2000

Triterpenic derivatives of Achillea alexandri-regis BORNM. & RUDSKI. ⬇️

scientific article published in December 2004

Two New Peltogynoids from Acacia nilotica Delile with Kinase Inhibitory Activity

scientific article published on 20 October 2009

Volatile profile of Greek dried white figs (Ficus carica L.) and investigation of the role of β-damascenone in aroma formation in fig liquors

scientific article

Volatile secondary metabolite pattern of callus cultures of Chamomilla recutita.

scientific article published in January 2001

seco-Cycloartane triterpenes from Gardenia aubryi

scientific article published on 01 December 2006

List of works by Prokopios Magiatis

"Pistacia lentiscus L." reduces the infarct size in normal fed anesthetized rabbits and possess antiatheromatic and hypolipidemic activity in cholesterol fed rabbits

1H NMR-based metabonomics for the classification of Greek wines according to variety, region, and vintage. Comparison with HPLC data

2,2-Dimethyl-2H-anthra[2,3-b]pyran-6,11-diones: a new class of cytotoxic compounds

2,3-cis-2R,3R-(-)-epiafzelechin-3-O-p-coumarate, a novel flavan-3-ol isolated from Fallopia convolvulus seed, is an estrogen receptor agonist in human cell lines.

3'-Substituted 7-halogenoindirubins, a new class of cell death inducing agents.

6-Br-5methylindirubin-3'oxime (5-Me-6-BIO) targeting the leishmanial glycogen synthase kinase-3 (GSK-3) short form affects cell-cycle progression and induces apoptosis-like death: exploitation of GSK-3 for treating leishmaniasis

6-Bromoindirubin-3'-oxime inhibits JAK/STAT3 signaling and induces apoptosis of human melanoma cells.

A Biomimetic, One-Step Transformation of Simple Indolic Compounds to Malassezia-Related Alkaloids with High AhR Potency and Efficacy

A Method for the Rapid Measurement of Alkylresorcinols in Flour, Bread and Related Products Based on 1H qNMR

A new process for the management of olive oil mill waste water and recovery of natural antioxidants

A novel 7-bromoindirubin with potent anticancer activity suppresses survival of human melanoma cells associated with inhibition of STAT3 and Akt signaling ⬇️

A traditional Chinese remedy points to a natural skin habitat: indirubin (indigo naturalis) for psoriasis and the Malassezia metabolome

Activity of grape extracts from Greek varieties of Vitis vinifera against mutagenicity induced by bleomycin and hydrogen peroxide in Salmonella typhimurium strain TA102.

AhR ligands, malassezin, and indolo[3,2-b]carbazole are selectively produced by Malassezia furfur strains isolated from seborrheic dermatitis.

Alkaloids from Sarcomelicope megistophylla

An Integrated Computational Approach to the Phenomenon of Potent and Selective Inhibition of Aurora Kinases B and C by a Series of 7-Substituted Indirubins

Asymmetric synthesis of gamma-keto-delta-lactam derivatives: application to the synthesis of a conformationally constrained surrogate of Ala-Ser dipeptide.

Biotechnological Approaches on Two High CBD and CBG <i>Cannabis sativa</i> L. (Cannabaceae) Varieties: In Vitro Regeneration and Phytochemical Consistency Evaluation of Micropropagated Plants Using Quantitative <sup>1</sup>H-NMR

Biotransformation of the flavonoid tiliroside to 7-methylether tiliroside: bioactivity of this metabolite and of its acetylated derivative

Chemical investigation and antimicrobial properties of mastic water and its major constituents.

Coelobillardin, an iridoid glucoside dimer from Coelospermum billardieri.

Composition and enantiomeric analysis of the essential oil of the fruits and the leaves of Pistacia vera from Greece

Could Malassezia yeasts be implicated in skin carcinogenesis through the production of aryl-hydrocarbon receptor ligands?

Coumarins from Peucedanum luxurians

Cultivar influence on variability in olive oil phenolic profiles determined through an extensive germplasm survey

Detection, Isolation, and ¹H NMR Quantitation of the Nitrile Glycoside Sarmentosin from a Bryophyllum pinnatum Hydro-Ethanolic Extract

Direct Analysis of Free and Sulfite-Bound Carbonyl Compounds in Wine by Two-Dimensional Quantitative Proton and Carbon Nuclear Magnetic Resonance Spectroscopy.

Direct measurement of oleocanthal and oleacein levels in olive oil by quantitative (1)H NMR. Establishment of a new index for the characterization of extra virgin olive oils.

Effect of cold temperature on the composition of different lipid classes of the foodborne pathogen Listeria monocytogenes: focus on neutral lipids

Effect of the form of the sesame-based diet on the absorption of lignans.

Estrogenic activity of phenylpropanoids from Sarcomelicope megistophylla and structure determination of a new norneolignan

GSK-3-selective inhibitors derived from Tyrian purple indirubins

Hemi-synthesis and biological activity of new analogues of podophyllotoxin.

Homarine, a common metabolite in edible Mediterranean molluscs: occurrence, spectral data and revision of a related structure.

Hydrolyzable tannins, the active constituents of three Greek Cytinus taxa against several tumor cell lines ⬇️

Hyperjovinols A and B: Two new phloroglucinol derivatives from Hypericum jovis with antioxidant activity in cell cultures.

Identification of black pine (Pinus nigra Arn.) heartwood as a rich source of bioactive stilbenes by qNMR.

Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins

Induction of discrete apoptotic pathways by bromo-substituted indirubin derivatives in invasive breast cancer cells ⬇️

Influence of Harvest Time and Malaxation Conditions on the Concentration of Individual Phenols in Extra Virgin Olive Oil Related to Its Healthy Properties

Isolation of megaritolactones and other bioactive metabolites from 'megaritiki' table olives and debittering water.

Malassezia yeasts produce a collection of exceptionally potent activators of the Ah (dioxin) receptor detected in diseased human skin

Malassezia-derived indoles activate the aryl hydrocarbon receptor and inhibit Toll-like receptor-induced maturation in monocyte-derived dendritic cells

Measuring protection of aromatic wine thiols from oxidation by competitive reactions vs wine preservatives with ortho-quinones

Natural and synthetic 2,2-dimethylpyranocoumarins with antibacterial activity.

New alkylresorcinols from a lipophilic extract of Urginea indica L. bulbs showing experimental trauma healing activity.

New lignans from the perisperm of Sesamum indicum

Novel Inverse Binding Mode of Indirubin Derivatives Yields Improved Selectivity for DYRK Kinases

Oil quality parameters and quantitative measurement of major secoiridoid derivatives in Neb Jmel olive oil from various Tunisian origins using qNMR.

Oleacein Attenuates the Pathogenesis of Experimental Autoimmune Encephalomyelitis through Both Antioxidant and Anti-Inflammatory Effects

Oleocanthal-rich extra virgin olive oil demonstrates acute anti-platelet effects in healthy men in a randomized trial

Oleocanthalic Acid, a Chemical Marker of Olive Oil Aging and Exposure to a High Storage Temperature with Potential Neuroprotective Activity

Oleuropein as a bioactive constituent added in milk and yogurt.

Oral administration of chios mastic gum or extracts in mice: quantification of triterpenic acids by liquid chromatography-tandem mass spectrometry

Photoreactivity of indirubin derivatives.

Phytochemical analysis of young fustic (Cotinus coggygria heartwood) and identification of isolated colourants in historical textiles.

Pityriazepin and other potent AhR ligands isolated from Malassezia furfur yeast

Quality profile determination of Chios mastic gum essential oil and detection of adulteration in mastic oil products with the application of chiral and non-chiral GC-MS analysis.

Quantitative measurement of major secoiridoid derivatives in olive oil using qNMR. Proof of the artificial formation of aldehydic oleuropein and ligstroside aglycon isomers

Quantitative method for determination of oleocanthal and oleacein in virgin olive oils by liquid chromatography-tandem mass spectrometry

S-(E)-Elenolide: a new constituent of extra virgin olive oil

Samioside, a new phenylethanoid glycoside with free-radical scavenging and antimicrobial activities from Phlomis samia.

Selective amination of secoiridoid glycosides to give monomeric pyridine, dimeric pyridine, and naphthyridine alkaloids.

Sesamolinol glucoside, disaminyl ether, and other lignans from sesame seeds

Soluble 3',6-substituted indirubins with enhanced selectivity toward glycogen synthase kinase -3 alter circadian period

Stability of oleuropein in the human proximal gut.

Structural basis for the synthesis of indirubins as potent and selective inhibitors of glycogen synthase kinase-3 and cyclin-dependent kinases

Structure elucidation and chromatographic identification of anthraquinone components of cochineal (Dactylopius coccus) detected in historical objects.

Synthesis and antiproliferative activity of 7-azaindirubin-3'-oxime, a 7-aza isostere of the natural indirubin pharmacophore.

Synthesis and antiproliferative activity of retroetoposide.

Synthesis and biological activity of esters in the trans-1,2-dihydroxy-1,2-dihydroacronycine series

Synthesis and biological evaluation of novel daunorubicin-estrogen conjugates.

Synthesis and cytotoxic activity of pyranocoumarins of the seselin and xanthyletin series

Synthesis of (R)-dihydropyridones as key intermediates for an efficient access to piperidine alkaloids

Synthesis of novel nitro-substituted triaryl pyrazole derivatives as potential estrogen receptor ligands.

The structure of sarcomejine: an application of long-range (1)H-(15)N correlation at natural abundance

Triterpenic derivatives of Achillea alexandri-regis BORNM. & RUDSKI. ⬇️

Two New Peltogynoids from Acacia nilotica Delile with Kinase Inhibitory Activity

Volatile profile of Greek dried white figs (Ficus carica L.) and investigation of the role of β-damascenone in aroma formation in fig liquors