List of works by Jacques Van Dongen

A DNA-PKcs mutation in a radiosensitive T-B- SCID patient inhibits Artemis activation and nonhomologous end-joining.

scientific article published on 15 December 2008

A model for predicting effect of treatment on progression-free survival using MRD as a surrogate endpoint in CLL.

scientific article published on 18 December 2017

A mutation in the human tetraspanin CD81 gene is expressed as a truncated protein but does not enable CD19 maturation and cell surface expression.

scientific article

A new type of radiosensitive T-B-NK+ severe combined immunodeficiency caused by a LIG4 mutation.

scientific article

A novel radiosensitive SCID patient with a pronounced G(2)/M sensitivity

scientific article

A probabilistic approach for the evaluation of minimal residual disease by multiparameter flow cytometry in leukemic B-cell chronic lymphoproliferative disorders.

scientific article

A quantitative immunoelectronmicroscopic study on soluble, membrane-associated and membrane-bound lysosomal enzymes in human intestinal epithelial cells

scientific article published on 01 October 1991

Aberrant methylation in promoter-associated CpG islands of multiple genes in acute lymphoblastic leukemia

scientific article published on 21 July 2005

Aberrant methylation in promoter-associated CpG islands of multiple genes in relapsed childhood acute lymphoblastic leukemia.

scientific article

Abnormal signal transduction in a patient with severe combined immunodeficiency disease

scientific article published on 01 March 1991

Acute lymphoblastic leukemia

scientific article published on 01 January 2002

Acute lymphoblastic leukemia followed by a clonally-unrelated EBV-positive non-Hodgkin lymphoma and a clonally-related myelomonocytic leukemia cutis.

scientific article published in April 2004

Age-associated distribution of normal B-cell and plasma cell subsets in peripheral blood.

scientific article published on 2 March 2018

Age-related changes in the cellular composition of the thymus in children

scientific article published on 01 April 2005

Ageing and latent CMV infection impact on maturation, differentiation and exhaustion profiles of T-cell receptor gammadelta T-cells

scientific article published on 14 July 2017

Allelotype analysis in relapsed childhood acute lymphoblastic leukemia

scientific article published on 01 October 2003

Alveolitis in an asymptomatic pigeon breeder

scientific article published on 01 February 1985

An antibody-deficiency syndrome due to mutations in the CD19 gene

scientific article (publication date: 4 May 2006)

An inv(16)(p13q22) positive acute myeloid leukaemia relapsing as acute precursor B-cell lymphoblastic leukaemia.

scientific article published in August 2004

Analysing the developing lymphocyte system of neonates and infants.

scientific article

Analysis of T cell receptor-gene rearrangement in T cells from the cerebrospinal fluid of patients with multiple sclerosis

scientific article published on 01 July 1987

Analysis of minimal residual disease by Ig/TCR gene rearrangements: guidelines for interpretation of real-time quantitative PCR data.

scientific article

Antibody deficiency due to a missense mutation in CD19 demonstrates the importance of the conserved tryptophan 41 in immunoglobulin superfamily domain formation

scientific article published on 17 February 2011

Antibody deficiency in patients with ataxia telangiectasia is caused by disturbed B- and T-cell homeostasis and reduced immune repertoire diversity.

scientific article published on 6 April 2013

Antigen receptor sequencing of paired bone marrow samples shows homogeneous distribution of acute lymphoblastic leukemia subclones

scientific article published on 31 August 2017

Application of germline IGH probes in real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia

scientific article published on 01 August 2000

Artemis splice defects cause atypical SCID and can be restored in vitro by an antisense oligonucleotide.

scientific article published on 10 March 2011

Autoimmune lymphoproliferative syndrome (ALPS) in a child from consanguineous parents: a dominant or recessive disease?

scientific article published on 01 March 2000

Automated database-guided expert-supervised orientation for immunophenotypic diagnosis and classification of acute leukemia

scientific article published in November 2017

Automated pattern-guided principal component analysis vs expert-based immunophenotypic classification of B-cell chronic lymphoproliferative disorders: a step forward in the standardization of clinical immunophenotyping

scientific article

Automated pattern-guided principal component analysis vs expert-based immunophenotypic classification of B-cell chronic lymphoproliferative disorders: a step forward in the standardization of clinical immunophenotyping.

scientific article published on 9 February 2011

B-cell development and functions and therapeutic options in adenosine deaminase-deficient patients.

scientific article published on 5 February 2014

B-cell maturation and antibody responses in individuals carrying a mutated CD19 allele.

scientific article published on 6 May 2010

B-cell prolymphocytic leukemia: a specific subgroup of mantle cell lymphoma

scientific article

B-cell recovery after stem cell transplantation of Artemis-deficient SCID requires elimination of autologous bone marrow precursor-B-cells

scientific article published on 01 December 2006

B-cell replication history and somatic hypermutation status identify distinct pathophysiologic backgrounds in common variable immunodeficiency

scientific article published on 31 October 2011

BI-28NEW MONOCYTE SUBTYPING DISTINGUISHES GLIOMA PATIENTS FROM HEALTHY CONTROLS.

scientific article

BIOMED-1 Concerted Action report: Flow cytometric characterization of CD7+ cell subsets in normal bone marrow as a basis for the diagnosis and follow-up of T cell acute lymphoblastic leukemia (T-ALL)

scientific article published on 28 April 2000

BIOMED-1 concerted action report: flow cytometric immunophenotyping of precursor B-ALL with standardized triple-stainings

scientific article published on 26 July 2001

BIOMED-2 multiplex immunoglobulin/T-cell receptor polymerase chain reaction protocols can reliably replace Southern blot analysis in routine clonality diagnostics.

scientific article published on October 2005

BMA031, a monoclonal antibody suited to identify the T-cell receptor alpha beta/CD3 complex on viable human T lymphocytes in normal and disease states

scientific article published on 01 November 1990

BMI1 as oncogenic candidate in a novel TCRB-associated chromosomal aberration in a patient with TCRgammadelta+ T-cell acute lymphoblastic leukemia

scientific article published on 08 November 2007

Basal Ca(2+) signaling is particularly increased in mutated chronic lymphocytic leukemia.

scientific article published on 11 June 2014

Basic helix-loop-helix proteins E2A and HEB induce immature T-cell receptor rearrangements in nonlymphoid cells.

scientific article published on October 2001

Basophil-lineage commitment in acute promyelocytic leukemia predicts for severe bleeding after starting therapy

scientific article published on 23 March 2018

Biased Iglambda expression in hypermutated IgD multiple myelomas does not result from receptor revision.

scientific article published in July 2002

Bilateral Exudative Pleuritis, an Unusual Pulmonary Onset of Mixed Connective Tissue Disease

scientific article published on 01 January 1985

Bimodal distribution of genomic MLL breakpoints in infant acute lymphoblastic leukemia treatment

scientific article published on 18 February 2010

Bone marrow immunophenotyping by flow cytometry in refractory cytopenia of childhood

scientific article

Breakpoint sites disclose the role of the V(D)J recombination machinery in the formation of T-cell receptor (TCR) and non-TCR associated aberrations in T-cell acute lymphoblastic leukemia

scientific article published on August 2013

Bronchoalveolar lavage in extrapulmonary sarcoidosis

scientific article published on 01 July 1988

CALM-AF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes.

scientific article

CD123 expression levels in 846 acute leukemia patients based on standardized immunophenotyping

scientific article published on 18 November 2018

CD21 and CD19 deficiency: Two defects in the same complex leading to different disease modalities

scientific article published on 29 August 2015

CD33 expression and P-glycoprotein-mediated drug efflux inversely correlate and predict clinical outcome in patients with acute myeloid leukemia treated with gemtuzumab ozogamicin monotherapy

scientific article

CD38 expression in paediatric leukaemia and lymphoma: implications for antibody targeted therapy

scientific article published on 08 September 2016

CD3G gene defects in familial autoimmune thyroiditis.

scientific article

CD81 gene defect in humans disrupts CD19 complex formation and leads to antibody deficiency

scientific article

Cancer research in the European community--report from a meeting in Stockholm in 1995

scientific article published on 01 July 1996

Checkpoints of B cell differentiation: visualizing Ig-centric processes.

scientific article published in December 2011

Childhood secondary ALL after ALL treatment.

scientific article

Chromosome 14 copy number-dependent IGH gene rearrangement patterns in high hyperdiploid childhood B-cell precursor ALL: implications for leukemia biology and minimal residual disease analysis

article

Circulating CD21low B cells in common variable immunodeficiency resemble tissue homing, innate-like B cells.

scholarly article

Circulating Human CD27-IgA+ Memory B Cells Recognize Bacteria with Polyreactive Igs

scientific article

Circulating T Cells of Patients with Nijmegen Breakage Syndrome Show Signs of Senescence.

scientific article published on 21 December 2016

Classification systems for acute and chronic leukaemias

scientific article published on December 2003

Clearance of maternal leukaemic cells in a neonate

scientific article published on 01 July 2001

Clinical heterogeneity can hamper the diagnosis of patients with ZAP70 deficiency

scientific article published on 29 May 2008

Clinical significance of flowcytometric minimal residual disease detection in pediatric acute myeloid leukemia patients treated according to the DCOG ANLL97/MRC AML12 protocol

scientific article published on 29 July 2010

Clinical spectrum of LIG4 deficiency is broadened with severe dysmaturity, primordial dwarfism, and neurological abnormalities

scientific article published on 18 September 2013

Clonal T- and natural killer-cell large granular lymphocyte proliferations in a single patient established by array-based comparative genomic hybridization analysis

scientific article published on 26 October 2006

Clonality analysis for antigen receptor genes: preliminary results from the Biomed-2 concerted action PL 96-3936.

scientific article

Cluster analysis of genomic ETV6-RUNX1 (TEL-AML1) fusion sites in childhood acute lymphoblastic leukemia.

scientific article

Combined TCRG and TCRA TREC analysis reveals increased peripheral T-lymphocyte but constant intra-thymic proliferative history upon ageing.

scientific article published on 19 September 2012

Comments on EuroFlow standard operating procedures for instrument setup and compensation for BD FACS Canto II, Navios and BD FACS Lyric instruments

scientific article published on 23 October 2019

Common variable immunodeficiency and idiopathic primary hypogammaglobulinemia: two different conditions within the same disease spectrum

scientific article published on 10 June 2013

Comparative analysis of Ig and TCR gene rearrangements at diagnosis and at relapse of childhood precursor-B-ALL provides improved strategies for selection of stable PCR targets for monitoring of minimal residual disease

scientific article published on 01 April 2002

Comparative analysis of T-cell receptor gene rearrangements at diagnosis and relapse of T-cell acute lymphoblastic leukemia (T-ALL) shows high stability of clonal markers for monitoring of minimal residual disease and reveals the occurrence of secon

scientific article published on 01 November 2003

Composition of precursor B-cell compartment in bone marrow from patients with X-linked agammaglobulinemia compared with healthy children.

scientific article

Confirmation of the assignment of the gene coding for the BA-2 antigen to human chromosome 12

scientific article published on 01 January 1984

Consensus guidelines for microarray gene expression analyses in leukemia from three European leukemia networks

scientific article published on 08 June 2006

Consensus guidelines for myeloma minimal residual disease sample staining and data acquisition

scientific article

Correct interpretation of T-ALL oncogene expression relies on normal human thymocyte subsets as reference material

scientific article published on 05 November 2011

Correction of B-cell development in Btk-deficient mice using lentiviral vectors with codon-optimized human BTK.

scientific article published on 24 June 2010

Correction of murine Rag1 deficiency by self-inactivating lentiviral vector-mediated gene transfer.

scientific article published on 27 May 2011

Correction to: Circulating T Cells of Patients with Nijmegen Breakage Syndrome Show Signs of Senescence

scientific article published on 01 May 2018

Cranial irradiation is the major cause of learning problems in children treated for leukemia and lymphoma: a comparative study.

scientific article published in August 1997

Cross-lineage T cell receptor gene rearrangements occur in more than ninety percent of childhood precursor-B acute lymphoblastic leukemias: alternative PCR targets for detection of minimal residual disease

scientific article published on 01 February 1999

Cryptosporidium infection in patients with primary immunodeficiencies.

scientific article published in October 2007

Cytomegalovirus- and Epstein-Barr Virus-Induced T-Cell Expansions in Young Children Do Not Impair Naive T-cell Populations or Vaccination Responses: The Generation R Study.

scientific article published on 3 July 2015

DNA microarrays for comparison of gene expression profiles between diagnosis and relapse in precursor-B acute lymphoblastic leukemia: choice of technique and purification influence the identification of potential diagnostic markers.

scientific article

DNA-PKcs deficiency in human: long predicted, finally found.

scientific article published on December 2009

Decreased IL7Rα and TdT expression underlie the skewed immunoglobulin repertoire of human B-cell precursors from fetal origin

scientific article published on 23 September 2016

Defective B-cell memory in patients with Down syndrome

scientific article published on 23 August 2014

Deficiencies in the CD19 complex

scientific article published on 31 July 2018

Deregulated WNT signaling in childhood T-cell acute lymphoblastic leukemia.

scientific article published on 14 March 2014

Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936.

scientific article published on December 2003

Detailed immunophenotyping of B-cell precursors in regenerating bone marrow of acute lymphoblastic leukaemia patients: implications for minimal residual disease detection

scientific article published on 17 April 2017

Detection of T cell receptor beta (TCRB) gene rearrangement patterns in T cell malignancies by Southern blot analysis

scientific article published on 01 June 1999

Detection of abnormalities in B-cell differentiation pattern is a useful tool to predict relapse in precursor-B-ALL

scientific article published on 01 March 1999

Detection of clonal EBV episomes in lymphoproliferations as a diagnostic tool

scientific article published on 01 August 2002

Detection of minimal residual disease identifies differences in treatment response between T-ALL and precursor B-ALL.

scientific article published in June 2002

Detection of minimal residual disease in hematologic malignancies by real-time quantitative PCR: principles, approaches, and laboratory aspects.

scientific article

Diagnostic tool for the identification of MLL rearrangements including unknown partner genes

scientific article

Different chromosomal breakpoints impact the level of LMO2 expression in T-ALL

scientific article published on 14 March 2007

Differential expression of CD73, CD86 and CD304 in normal vs. leukemic B-cell precursors and their utility as stable minimal residual disease markers in childhood B-cell precursor acute lymphoblastic leukemia

scientific article published on 09 March 2018

Differentiation stage of myeloma plasma cells: biological and clinical significance.

scientific article

Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL.

scientific article

Dissection of B-cell development to unravel defects in patients with a primary antibody deficiency

scientific article published on January 2011

Disseminated bacillus Calmette-Guérin infection and immunodeficiency

scientific article published on May 2007

Dysregulated signaling, proliferation and apoptosis impact on the pathogenesis of TCRγδ+ T cell large granular lymphocyte leukemia.

scientific article

Early stages in the development of human T, natural killer and thymic dendritic cells.

scientific article published in October 1998

Easy detection of all T cell receptor gamma (TCRG) gene rearrangements by Southern blot analysis: recommendations for optimal results

scientific article published on 01 October 1999

Ectopic retroviral expression of LMO2, but not IL2Rgamma, blocks human T-cell development from CD34+ cells: implications for leukemogenesis in gene therapy.

scientific article published in February 2007

Effects of nongenetic factors on immune cell dynamics in early childhood: The Generation R Study

scientific article

Efficacy and safety of gemtuzumab ozogamicin in patients with CD33-positive acute myeloid leukemia in first relapse

scientific article (publication date: July 2001)

Efficient and easy detection of MLL-AF4, MLL-AF9 and MLL-ENL fusion gene transcripts by multiplex real-time quantitative RT-PCR in TaqMan and LightCycler.

scientific article

EuroClonality/BIOMED-2 guidelines for interpretation and reporting of Ig/TCR clonality testing in suspected lymphoproliferations.

scientific article published on 24 August 2012

EuroFlow Standardized Approach to Diagnostic Immunopheneotyping of Severe PID in Newborns and Young Children

scientific article published on 19 March 2020

EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes

scientific article

Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using 'real-time' quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR) - a Europe against cancer program.

scientific article

Expert-independent classification of mature B-cell neoplasms using standardized flow cytometry: a multicentric study

scientific article published in 2022

Expression of mdr1 and mdr3 multidrug-resistance genes in hairy cell leukaemia ⬇️

scientific article published on January 1, 1991

Expression of the human immunoglobulin heavy chain gene of the 14q+ chromosome in a t(8;14)-positive Burkitt lymphoma cell line demonstrated in somatic cell hybrids

scientific article published on 01 January 1986

Expression of the myeloid differentiation antigen CD33 depends on the presence of human chromosome 19 in human-mouse hybrids ⬇️

scientific article published on May 1, 1990

Expression profile of novel cell surface molecules on different subsets of human peripheral blood antigen-presenting cells.

scientific article published on 16 September 2016

Familial disseminated atypical mycobacterial infection in childhood

scientific article published on 01 April 1995

Fetal growth influences lymphocyte subset counts at birth: the Generation R Study

scientific article published on 6 September 2008

Final report of the efficacy and safety of gemtuzumab ozogamicin (Mylotarg) in patients with CD33-positive acute myeloid leukemia in first recurrence

scientific article

Flow cytometric analysis of normal B cell differentiation: a frame of reference for the detection of minimal residual disease in precursor-B-ALL

scientific article published on 01 March 1999

Flow cytometric analysis of the Vbeta repertoire in healthy controls

scientific article published on 01 August 2000

Flow cytometric assessment of leukocyte kinetics for the monitoring of tissue damage

scientific article published on 02 October 2018

Flow cytometric detection of intracellular antigens for immunophenotyping of normal and malignant leukocytes: testing of a new fixation-permeabilization solution

scientific article published on 01 December 1997

Flow cytometric immunobead assay for fast and easy detection of PML-RARA fusion proteins for the diagnosis of acute promyelocytic leukemia

scientific article

Flow cytometric immunobead assay for the detection of BCR-ABL fusion proteins in leukemia patients.

scientific article

Flow-cytometric immunophenotyping of normal and malignant lymphocytes

scientific article published on January 2006

Four aged siblings with B cell chronic lymphocytic leukemia

scientific article published on 01 December 1997

Frequent issues and lessons learned from EuroFlow QA

scientific article published on 17 September 2018

Gene therapy: is IL2RG oncogenic in T-cell development?

scientific article published in September 2006

Generation of flow cytometry data files with a potentially infinite number of dimensions.

scientific article

Genetic aberrations in paediatric acute leukaemias and implications for management of patients.

scientific article published on 07 May 2010

Genetic and demographic features of X-linked agammaglobulinemia in Eastern and Central Europe: a cohort study.

scientific article

Genetic and epigenetic determinants mediate proneness of oncogene breakpoint sites for involvement in TCR translocations

scientific article published on 05 December 2013

Genetic defects in PI3Kδ affect B-cell differentiation and maturation leading to hypogammaglobulineamia and recurrent infections.

scientific article published on 16 January 2017

Granulomatous slack skin. Report of three patients with an updated review of the literature.

scientific article published on January 1998

Gross deletions involving IGHM, BTK, or Artemis: a model for genomic lesions mediated by transposable elements.

scientific article published on February 2008

Harmonization of light scatter and fluorescence flow cytometry profiles obtained after staining peripheral blood leucocytes for cell surface-only versus intracellular antigens with the Fix & Perm reagent.

scientific article published in January 2010

Heteroduplex PCR analysis of rearranged T cell receptor genes for clonality assessment in suspect T cell proliferations

scientific article published on 01 December 1997

Heterogeneity in junctional regions of immunoglobulin kappa deleting element rearrangements in B cell leukemias: a new molecular target for detection of minimal residual disease

scientific article published on 01 December 1997

High-Throughput Immunogenetics for Clinical and Research Applications in Immunohematology: Potential and Challenges

scientific article published on 17 April 2017

High-risk childhood acute lymphoblastic leukemia in first remission treated with novel intensive chemotherapy and allogeneic transplantation.

scientific article

Homeostatic and maturation-associated proliferation in the peripheral B-cell compartment.

scientific article published on December 2007

How to make usage of the standardized EuroFlow 8-color protocols possible for instruments of different manufacturers.

scientific article published on 15 November 2017

Human CD19 and CD40L deficiencies impair antibody selection and differentially affect somatic hypermutation.

scientific article published on 11 January 2014

Human IgE(+) B cells are derived from T cell-dependent and T cell-independent pathways.

scientific article published on 13 May 2014

Human IgG2- and IgG4-expressing memory B cells display enhanced molecular and phenotypic signs of maturity and accumulate with age.

scientific article published on 26 May 2017

Human T-cell lines with well-defined T-cell receptor gene rearrangements as controls for the BIOMED-2 multiplex polymerase chain reaction tubes.

scientific article published on 14 December 2006

Human memory B cells originate from three distinct germinal center-dependent and -independent maturation pathways

scientific article published on 20 June 2011

Human peripheral blood B-cell compartments: a crossroad in B-cell traffic.

scientific article published on January 2010

Human thymus contains multipotent progenitors with T/B lymphoid, myeloid, and erythroid lineage potential.

scientific article published on 29 December 2005

IL-7R expression and IL-7 signaling confer a distinct phenotype on developing human B-lineage cells.

scientific article

Identification of Notch target genes in uncommitted T-cell progenitors: No direct induction of a T-cell specific gene program

scientific article published on 21 September 2006

Identification of a new cluster of T-cell receptor delta recombining elements.

scientific article

Identification of checkpoints in human T-cell development using severe combined immunodeficiency stem cells

scientific article published on 2 October 2015

Identification of e19a2 BCR-ABL fusions (mu-BCR breakpoints) at the DNA level by ligation-mediated PCR.

scientific article

Ig gene rearrangement steps are initiated in early human precursor B cell subsets and correlate with specific transcription factor expression

scientific article published on 01 November 2005

IgE-expressing memory B cells and plasmablasts are increased in blood of children with asthma, food allergy and atopic dermatitis.

scientific article published on 30 January 2018

Immunobiological diversity in infant acute lymphoblastic leukemia is related to the occurrence and type of MLL gene rearrangement.

scientific article published in February 2007

Immunocytochemistry of lysosomal hydrolases and their precursor forms in normal and mutant human cells

scientific article published on 01 September 1984

Immunogenotype changes prevail in relapses of young children with TEL-AML1-positive acute lymphoblastic leukemia and derive mainly from clonal selection

scientific article published on 01 November 2005

Immunoglobulin gene rearrangements and the pathogenesis of multiple myeloma.

scientific article published on 18 July 2007

Immunoglobulin kappa deleting element rearrangements in precursor-B acute lymphoblastic leukemia are stable targets for detection of minimal residual disease by real-time quantitative PCR

scientific article published on 01 May 2002

Immunoglobulin lambda isotype gene rearrangements in B cell malignancies

scientific article published on 01 January 2001

Immunoglobulin light chain gene rearrangements display hierarchy in absence of selection for functionality in precursor-B-ALL

scientific article published on 01 August 2002

Immunoglobulin light chain gene rearrangements in precursor-B-acute lymphoblastic leukemia: characteristics and applicability for the detection of minimal residual disease.

scientific article

Immunoglobulin/T-cell receptor clonality diagnostics.

scientific article published on December 2007

Immunological characterisation of cells in cerebrospinal fluid from patients with lymphoid malignancies

scientific article published on 01 March 1984

Immunological marker analysis of mitogen-induced proliferating lymphocytes using BrdU incorporation or screening of metaphases. Staphylococcal protein A is a potent mitogen for CD4+ lymphocytes

scientific article published on 01 December 1990

Immunophenotype of normal vs. myeloma plasma cells: Toward antibody panel specifications for MRD detection in multiple myeloma

scientific article published on 23 June 2015

Immunophenotypic alterations of bone marrow myeloid cell compartments in multiple myeloma patients predict for myelodysplasia-associated cytogenetic alterations

scientific article published on 14 March 2014

Immunophenotypic and immunogenotypic characteristics of TCRgammadelta+ T cell acute lymphoblastic leukemia

scientific article published on 01 February 1999

Immunophenotypical detection of minimal residual disease in acute leukemia.

scientific article

Immunophenotyping of blood lymphocytes in childhood. Reference values for lymphocyte subpopulations

scientific article published on 01 March 1997

In Vitro Measles Virus Infection of Human Lymphocyte Subsets Demonstrates High Susceptibility and Permissiveness of both Naive and Memory B Cells

scientific article published on 7 February 2018

Incomplete DJH rearrangements of the IgH gene are frequent in multiple myeloma patients: immunobiological characteristics and clinical implications.

scientific article published in July 2003

Increased PI3K/Akt activity and deregulated humoral immune response in human PTEN deficiency.

scientific article published on 13 August 2016

Induction of clinical remission in T-large granular lymphocyte leukemia with cyclosporin A, monitored by use of immunophenotyping with Vbeta antibodies.

scientific article

Inhibition affecting RQ-PCR-based assessment of minimal residual disease in acute lymphoblastic leukemia: reversal by addition of bovine serum albumin.

scientific article

Internalization and cell cycle-dependent killing of leukemic cells by Gemtuzumab Ozogamicin: rationale for efficacy in CD33-negative malignancies with endocytic capacity ⬇️

scientific article published on February 1, 2004

Introduction to the diagnosis and classification of monocytic-lineage leukemias by flow cytometry

scientific article published on 18 August 2015

Invasive Aspergillus infection in chronic granulomatous disease: treatment with itraconazole

scientific article published on 01 December 1989

Involvement of Artemis in nonhomologous end-joining during immunoglobulin class switch recombination

scientific article published on 15 December 2008

Lack of common TCRA and TCRB clonotypes in CD8(+)/TCRαβ(+) T-cell large granular lymphocyte leukemia: a review on the role of antigenic selection in the immunopathogenesis of CD8(+) T-LGL

scientific article published on 10 January 2014

Late recurrence of childhood T-cell acute lymphoblastic leukemia frequently represents a second leukemia rather than a relapse: first evidence for genetic predisposition.

scientific article published on 28 February 2011

Level of minimal residual disease prior to haematopoietic stem cell transplantation predicts prognosis in paediatric patients with acute lymphoblastic leukaemia: a report of the Pre-BMT MRD Study Group

scientific article published on 01 October 2003

Linkage analysis for ATM in familial B cell chronic lymphocytic leukaemia

scientific article published on 01 October 1999

Longitudinal follow-up of blood lymphocyte subpopulations from birth to 1 year of age

scientific article published on 01 October 1998

Longitudinal survey of lymphocyte subpopulations in the first year of life.

scientific article published in April 2000

Loss of juxtaposition of RAG-induced immunoglobulin DNA ends is implicated in the precursor B-cell differentiation defect in NBS patients.

scientific article published on 8 April 2010

Lot-to-lot stability of antibody reagents for flow cytometry

scientific article published on 29 March 2017

Lymphoma with multi-gene rearrangement on the level of immunoglobulin heavy chain, light chain, and T-cell receptor beta chain

scientific article published on 01 September 1998

MRD detection in B-cell non-Hodgkin lymphomas using Ig gene rearrangements and chromosomal translocations as targets for real-time quantitative PCR.

scientific article

MRD detection in acute lymphoblastic leukemia patients using Ig/TCR gene rearrangements as targets for real-time quantitative PCR

scientific article published on 01 January 2009

Minimal residual disease diagnostics in acute lymphoblastic leukaemia: impact of primer characteristics and size of junctional regions

scientific article published on 26 October 2013

Minimal residual disease diagnostics in acute lymphoblastic leukemia: need for sensitive, fast, and standardized technologies

scientific article

Minimal residual disease levels in bone marrow and peripheral blood are comparable in children with T cell acute lymphoblastic leukemia (ALL), but not in precursor-B-ALL

scientific article published on 01 August 2002

Minimal residual disease monitoring and immune profiling in multiple myeloma in elderly patients

scientific article

Minimal residual disease prior to stem cell transplant for childhood acute lymphoblastic leukaemia.

scientific article

Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leu

scientific article published on 31 January 2008

Molecular and flow cytometric analysis of the Vbeta repertoire for clonality assessment in mature TCRalphabeta T-cell proliferations

scientific article published on 01 July 2001

Molecular detection of minimal residual disease is a strong predictive factor of relapse in childhood B-lineage acute lymphoblastic leukemia with medium risk features. A case control study of the International BFM study group.

scientific article published in November 2000

Molecular diagnostics of primary immunodeficiencies: benefits and future challenges

scientific article

Molecular discrimination between relapsed and secondary acute lymphoblastic leukemia: proposal for an easy strategy

scientific article published on 01 March 2001

Molecular monitoring of residual disease using antigen receptor genes in childhood acute lymphoblastic leukaemia.

scientific article

Molecular remission is an independent predictor of clinical outcome in patients with mantle cell lymphoma after combined immunochemotherapy: a European MCL intergroup study

scientific article

Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study

scientific article published on 12 February 2010

Morbidly obese human subjects have increased peripheral blood CD4+ T cells with skewing toward a Treg- and Th2-dominated phenotype.

scientific article published on 6 January 2012

Multicolor flowcytometric immunophenotyping is a valuable tool for detection of intraocular lymphoma.

scientific article published on 4 February 2013

New cellular markers at diagnosis are associated with isolated central nervous system relapse in paediatric B-cell precursor acute lymphoblastic leukaemia

scientific article

New criteria for response assessment: role of minimal residual disease in multiple myeloma

scientific article

New frontiers of primary antibody deficiencies.

scientific article

New insights and unresolved issues regarding insertional mutagenesis in X-linked SCID gene therapy

scientific article published on 28 August 2007

New insights on human T cell development by quantitative T cell receptor gene rearrangement studies and gene expression profiling.

scientific article published on 31 May 2005

Next Generation Flow for highly sensitive and standardized detection of minimal residual disease in multiple myeloma.

scientific article published on 20 January 2017

Next generation flow for minimally-invasive blood characterization of MGUS and multiple myeloma at diagnosis based on circulating tumor plasma cells (CTPC)

scientific article published on 19 November 2018

Next-Generation Sequencing Analysis of the Human TCRγδ+ T-Cell Repertoire Reveals Shifts in Vγ- and Vδ-Usage in Memory Populations upon Aging.

scientific article published on 6 March 2018

Next-generation sequencing indicates false-positive MRD results and better predicts prognosis after SCT in patients with childhood ALL.

scientific article

No significant prognostic value of normal precursor B-cell regeneration in paediatric acute myeloid leukaemia after induction treatment

scientific article published on 12 April 2013

Non-specific amplification of patient-specific Ig/TCR gene rearrangements depends on the time point during therapy: implications for minimal residual disease monitoring

scientific article published on 13 September 2007

Novel insights into the development of T-cell acute lymphoblastic leukemia.

scientific article published on July 2007

Nuclear positioning rather than contraction controls ordered rearrangements of immunoglobulin loci.

scientific article published on 17 September 2015

Oligoclonal gammopathy in phenotypic diarrhea

scientific article published on 01 March 2000

Oncolytic virotherapy in glioblastoma patients induces a tumor macrophage phenotypic shift leading to an altered glioblastoma microenvironment.

scientific article

Optimization and testing of dried antibody tube: The EuroFlow LST and PIDOT tubes as examples

scientific article published on 21 March 2017

Optimization of PCR-based minimal residual disease diagnostics for childhood acute lymphoblastic leukemia in a multi-center setting.

scientific article published on 8 February 2007

Ordered recombination of immunoglobulin light chain genes occurs at the IGK locus but seems less strict at the IGL locus

scientific article published on 01 February 2001

Overview of clinical flow cytometry data analysis: recent advances and future challenges

scientific article

PID comes full circle: applications of V(D)J recombination excision circles in research, diagnostics and newborn screening of primary immunodeficiency disorders.

scientific article published on 4 May 2011

PJA-BP expression and TCR delta deletion during human T cell differentiation

scientific article published on 01 December 1998

Perinatal stress influences lymphocyte subset counts in neonates. The generation R study

scientific article

Persistent polyclonal B-cell lymphocytosis: extensively proliferated CD27+IgM+IgD+ memory B cells with a distinctive immunophenotype.

scientific article

Persistent subclinical immune defects in HIV-1-infected children treated with antiretroviral therapy

scientific article published on September 2015

Phenotype of blood monocytes and alveolar macrophages in interstitial lung disease

scientific article published on 01 March 1989

Phenotypic and genotypic characteristics of human early T-cell differentiation: the T-cell acute lymphoblastic leukaemia model.

scientific article published on February 1994

Phenotypic profile of expanded NK cells in chronic lymphoproliferative disorders: a surrogate marker for NK-cell clonality

scientific article published on 6 November 2015

Pitfalls in TCR gene clonality testing: teaching cases.

scientific article published on 22 August 2008

Population matched (pm) germline allelic variants of immunoglobulin (IG) loci: Relevance in infectious diseases and vaccination studies in human populations

scientific article published on 12 June 2021

Precursor-B-ALL with D(H)-J(H) gene rearrangements have an immature immunogenotype with a high frequency of oligoclonality and hyperdiploidy of chromosome 14

scientific article published on 01 September 2001

Preemptive alloimmune intervention in high-risk pediatric acute lymphoblastic leukemia patients guided by minimal residual disease level before stem cell transplantation

scientific article published on 10 June 2010

Prenatal origin of hyperdiploid acute lymphoblastic leukemia in identical twins.

scientific article published on November 2003

Prognostic significance of minimal residual disease in infants with acute lymphoblastic leukemia treated within the Interfant-99 protocol.

scientific article published on 12 February 2009

Prognostic value of MRD in CLL patients with comorbidities receiving chlorambucil plus obinutuzumab or rituximab

scientific article published on 19 November 2018

Prognostic value of minimal residual disease in acute lymphoblastic leukaemia in childhood.

scientific article

Pulmonary mycobacterium avium intracellulare infection in an immunocompetent child.

scientific article

Purity for clarity: the need for purification of tumor cells in DNA microarray studies

scientific article published on 01 April 2005

Quality assessment program for EuroFlow protocols: summary results of four-year (2010-2013) quality assurance rounds

scientific article published on 23 October 2014

Quantification of newly developed T cells in mice by real-time quantitative PCR of T-cell receptor rearrangement excision circles

scientific article published on 01 July 2002

Radiosensitive SCID patients with Artemis gene mutations show a complete B-cell differentiation arrest at the pre-B-cell receptor checkpoint in bone marrow.

scientific article

Real-time quantitative (RQ-)PCR approach to quantify the contribution of proliferation to B lymphocyte homeostasis.

scientific article published in January 2013

Real-time quantitative PCR for detection of minimal residual disease before allogeneic stem cell transplantation predicts outcome in children with acute lymphoblastic leukemia

scientific article published on 01 September 2001

Real-time quantitative PCR for the detection of minimal residual disease in acute lymphoblastic leukemia using junctional region specific TaqMan probes

scientific article published on 01 December 1998

Rearrangements of the human TCRD-deleting elements

scientific article published on 01 January 1994

Recombination in the human IGK locus

scientific article

Regenerating normal B-cell precursors during and after treatment of acute lymphoblastic leukaemia: implications for monitoring of minimal residual disease

scientific article published on 01 July 2000

Regeneration pattern of precursor-B-cells in bone marrow of acute lymphoblastic leukemia patients depends on the type of preceding chemotherapy

scientific article published on 01 April 2000

Replication history of B lymphocytes reveals homeostatic proliferation and extensive antigen-induced B cell expansion

scientific article

Residual normal B-cell profiles in monoclonal B-cell lymphocytosis versus chronic lymphocytic leukemia

scientific article published on 21 June 2018

Role of Artemis in DSB repair and guarding chromosomal stability following exposure to ionizing radiation at different stages of cell cycle.

scientific article published on 12 December 2006

SIHONSCORE: a scoring system for external quality control of leukaemia/lymphoma immunophenotyping measuring all analytical phases of laboratory performance

scientific article published on 01 February 2001

Selection and validation of antibody clones against IgG and IgA subclasses in switched memory B-cells and plasma cells.

scientific article

Similar recombination-activating gene (RAG) mutations result in similar immunobiological effects but in different clinical phenotypes

scientific article published on 11 January 2014

Site-specific deletions involving the tal-1 and sil genes are restricted to cells of the T cell receptor alpha/beta lineage: T cell receptor delta gene deletion mechanism affects multiple genes.

scientific article published on April 1993

Spectrum of T-large granular lymphocyte lymphoproliferations: ranging from expanded activated effector T cells to T-cell leukaemia

scientific article published on 01 November 2003

Split-signal FISH for detection of chromosome aberrations.

scientific article

Staging of Sezary syndrome with somatostatin receptor scintigraphy

scientific article published on 01 January 1996

Standardised immunophenotypic analysis of myeloperoxidase in acute leukaemia

scientific article published on 07 November 2020

Standardization and quality control studies of 'real-time' quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia - a Europe Against Cancer program.

scientific article published on December 2003

Standardization of DNA isolation from low cell numbers for chimerism analysis by PCR of short tandem repeats

scientific article published on 17 June 2011

Standardized flow cytometry for highly sensitive MRD measurements in B-cell acute lymphoblastic leukemia

scientific article

Strategies for B-cell receptor repertoire analysis in primary immunodeficiencies: from severe combined immunodeficiency to common variable immunodeficiency

scientific article published on 08 April 2015

Studying the replication history of human B lymphocytes by real-time quantitative (RQ)-PCR.

scientific article

Successful RAG1-SCID gene therapy depends on the level of RAG1 expression.

scientific article published on 26 June 2014

Successful Therapy Reduction and Intensification for Childhood Acute Lymphoblastic Leukemia Based on Minimal Residual Disease Monitoring: Study ALL10 From the Dutch Childhood Oncology Group

scientific article published on 6 June 2016

Sucrase-isomaltase and cystic fibrosis

scientific article published on 01 January 1985

Suitable DNA isolation method for the detection of minimal residual disease by PCR techniques

scientific article published on 01 August 1999

T cell receptor gamma (TCRG) gene rearrangements in T cell acute lymphoblastic leukemia refelct 'end-stage' recombinations: implications for minimal residual disease monitoring

scientific article published on 01 July 2000

T cell receptor gamma gene rearrangements as targets for detection of minimal residual disease in acute lymphoblastic leukemia by real-time quantitative PCR analysis

scientific article published on 01 July 2002

T-cell receptor Vβ skewing frequently occurs in refractory cytopenia of childhood and is associated with an expansion of effector cytotoxic T cells: a prospective study by EWOG-MDS.

scientific article

T-lymphocytes in bone marrow samples of children with acute lymphoblastic leukemia during and after chemotherapy might hamper PCR-based minimal residual disease studies

scientific article published on 01 August 2001

TACI mutations and disease susceptibility in patients with common variable immunodeficiency.

scientific article published on 11 December 2008

TCRB gene rearrangements in childhood and adult precursor-B-ALL: frequency, applicability as MRD-PCR target, and stability between diagnosis and relapse

scientific article published on 01 December 2004

TMIC-03. ONCOLYTIC VIRAL THERAPY WITH DELTA24-RGD INDUCES A TUMOR-DETRIMENTAL ENVIRONMENT VIA PHENOTYPIC SHIFT OF MACROPHAGES

TdT positive B-cell acute lymphoblastic leukaemia (B-ALL) without Burkitt characteristics

scientific article published on 01 April 1988

The 3D structure of the immunoglobulin heavy-chain locus: implications for long-range genomic interactions.

scientific article published on April 2008

The EuroChimerism concept for a standardized approach to chimerism analysis after allogeneic stem cell transplantation.

scientific article

The Human Thymus Is Enriched for Autoreactive B Cells.

scientific article published on 3 June 2016

The MLL recombinome of acute leukemias

scientific article published on 01 May 2006

The MLL recombinome of acute leukemias in 2013.

scientific article

The clinical relevance of minor paroxysmal nocturnal hemoglobinuria clones in refractory cytopenia of childhood: a prospective study by EWOG-MDS.

scientific article published on 28 June 2013

The defect in humoral immunity in patients with Nijmegen breakage syndrome is explained by defects in peripheral B lymphocyte maturation.

scientific article published on 31 July 2012

The effect of a novel recombination between the homeobox gene NKX2-5 and the TRD locus in T-cell acute lymphoblastic leukemia on activation of the NKX2-5 gene.

scientific article published on March 2006

The human androgen receptor X-chromosome inactivation assay for clonality diagnostics of natural killer cell proliferations

scientific article published in July 2007

The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency ⬇️

scientific article published on 17 January 2011

The immunophenotypic and immunogenotypic B-cell differentiation arrest in bone marrow of RAG-deficient SCID patients corresponds to residual recombination activities of mutated RAG proteins.

scientific article published in September 2002

The nature of circulating CD27+CD43+ B cells.

scientific article published in December 2011

The novel calicheamicin-conjugated CD22 antibody inotuzumab ozogamicin (CMC-544) effectively kills primary pediatric acute lymphoblastic leukemia cells.

scientific article

The nuclear effector of Wnt-signaling, Tcf1, functions as a T-cell-specific tumor suppressor for development of lymphomas

scientific article

The potential use of basigin (CD147) as a prognostic marker in B-cell precursor acute lymphoblastic leukaemia

scientific article published on 20 May 2010

The same IkappaBalpha mutation in two related individuals leads to completely different clinical syndromes.

scientific article

Thyrotropin acts as a T-cell developmental factor in mice and humans.

scientific article published on 15 May 2014

Transient reduction in IgA+ and IgG+ memory B cell numbers in young EBV-seropositive children: the Generation R Study.

scientific article published on 7 November 2016

Translocation detection in lymphoma diagnosis by split-signal FISH: a standardised approach

scientific article published on 29 August 2008

Triple immunological staining with colloidal gold, fluorescein and rhodamine as labels

scientific article published on 01 June 1985

Two consecutive immunophenotypic switches in a child with immunogenotypically stable acute leukaemia

scientific article published on 01 June 2001

Two patients with complete defects in interferon gamma receptor-dependent signaling

scientific article published on 21 May 2007

Two types of gamma T cell receptors expressed by T cell acute lymphoblastic leukemias

scientific article published on 01 December 1987

Ultrastructural localization of steroid sulphatase in cultured human fibroblasts by immunocytochemistry: a comparative study with lysosomal enzymes and the mannose 6-phosphate receptor

scientific article published on 01 January 1988

Understanding the reconstitution of the B-cell compartment in bone marrow and blood after treatment for B-cell precursor acute lymphoblastic leukaemia.

scientific article

Unraveling of the polymorphic C lambda 2-C lambda 3 amplification and the Ke+Oz- polymorphism in the human Ig lambda locus

scientific article published on 01 July 2002

Unraveling the consecutive recombination events in the human IGK locus.

scientific article published on September 2004

Utility of CD54, CD229, and CD319 for the identification of plasma cells in patients with clonal plasma cell diseases

scientific article published on 31 July 2015

Validation of BIOMED-2 multiplex PCR tubes for detection of TCRB gene rearrangements in T-cell malignancies

scientific article published on 01 September 2004

Vdelta2-Jalpha rearrangements are frequent in precursor-B-acute lymphoblastic leukemia but rare in normal lymphoid cells.

scientific article

Wnt signaling in the thymus is regulated by differential expression of intracellular signaling molecules

scholarly article

Wnt target genes identified by DNA microarrays in immature CD34+ thymocytes regulate proliferation and cell adhesion.

scientific article published on January 2004

Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation

scientific article published on 02 October 2008

Wnt3a nonredundantly controls hematopoietic stem cell function and its deficiency results in complete absence of canonical Wnt signaling

scientific article published on 01 July 2010

XLA patients with BTK splice-site mutations produce low levels of wild-type BTK transcripts

scientific article published on 01 September 2002

XLF deficiency results in reduced N-nucleotide addition during V(D)J recombination.

scientific article

[Minimal residual disease in childhood acute lymphoblastic leukemia: diagnosis of the 21 century]

scientific article published on 01 January 2003

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