List of works by Paul T Sharpe

A mathematical model for mechanotransduction at the early steps of suture formation

scientific article (publication date: 22 May 2013)

A quiescent cell population replenishes mesenchymal stem cells to drive accelerated growth in mouse incisors

scientific article

A role for suppressed incisor cuspal morphogenesis in the evolution of mammalian heterodont dentition

scientific article (publication date: 5 January 2010)

Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling

scientific journal article

Activated WNT signaling in postnatal SOX2-positive dental stem cells can drive odontoma formation

scientific article

Activin is an essential early mesenchymal signal in tooth development that is required for patterning of the murine dentition

scientific article

Adult human gingival epithelial cells as a source for whole-tooth bioengineering

scientific article published on 04 March 2013

Amelogenin in cranio-facial development: the tooth as a model to study the role of amelogenin during embryogenesis.

scientific article published on July 2009

An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes

scientific article

An enhancer sequence directs LacZ expression to developing pharyngeal endoderm in transgenic mice.

scientific article published in October 2001

Analysis of cDNAs from a mouse embryo tooth library: identification of novel genes during tooth development

scientific article

Analysis of neural crest-derived clones reveals novel aspects of facial development

scientific article

Antagonistic regulation of Dlx2 expression by PITX2 and Msx2: implications for tooth development

scientific article (publication date: 2001)

Axin2-expressing cells differentiate into reparative odontoblasts via autocrine Wnt/β-catenin signaling in response to tooth damage

scientific article published on 8 June 2017

BEN/DM-GRASP/SC1 expression during mouse facial development: differential expression and regulation in molars and incisors.

scientific article published in June 2003

Barx1 and evolutionary changes in feeding

scientific article

Barx1-mediated inhibition of Wnt signaling in the mouse thoracic foregut controls tracheo-esophageal septation and epithelial differentiation

scientific article

Biological tooth replacement

scientific article published on October 2006

Biological tooth replacement and repair.

scientific article published on December 2007

Bmp signalling in filiform tongue papillae development.

scientific article published on 18 December 2011

Canine bone marrow cell cultures infected with canine distemper virus: an in vitro model of Paget's disease.

scientific article published in October 1995

Canine distemper virus localised in bone cells of patients with Paget's disease

scientific article

Caspase-7 in molar tooth development.

scientific article published in August 2012

Caspase-7 participates in differentiation of cells forming dental hard tissues

scientific article published on 29 May 2013

Cell-surface changes induced by ectopic expression of the murine homeobox gene Hox-3.3.

scientific article

Central nervous system malformations and deformations in FGFR2-related craniosynostosis.

scientific article

Changes in the DNA content of amoebae of Dictyostelium discoideum during growth and development.

scientific article published on February 1984

Characterisation of the genomic canine Fgf8 locus and screen for genetic variants in 4 dogs with different face types

scientific article published in June 2007

Characterisation of the genomic structure of chick Fgf8.

scientific article

Characterisation of the murine Hox-3.3 gene and its promoter ⬇️

scientific article published on September 1, 1991

Characterization of a mouse Scube3 reporter line.

scientific article published on 19 November 2010

Characterization of progenitor/stem cell population from human dental socket and their multidifferentiation potential

scientific article published on 05 December 2019

Chromosomal and temperature-dependent sex determination: The search for a conserved mechanism

scientific article published on 01 September 1994

Cloning and expression analysis of two ZFY-related zinc finger genes from Alligator mississippiensis, a species with temperature-dependent sex determination

scientific article published on October 1, 1992

Coevolutionary patterning of teeth and taste buds

scientific article

Conserved regulation of mesenchymal gene expression by Fgf-8 in face and limb development

scientific journal article

Contribution of mesoderm to the developing dental papilla

scientific article published on 01 January 2011

Contribution of nuclear and extranuclear polyQ to neurological phenotypes in mouse models of Huntington's disease

scientific article published on 23 September 2005

Coordination of epithelial branching and salivary gland lumen formation by Wnt and FGF signals.

scientific article

Correction: Lrp4 Modulates Extracellular Integration of Cell Signaling Pathways in Development

scientific article published on 8 January 2009

Correction: the buccohypophyseal canal is an ancestral vertebrate trait maintained by modulation in sonic hedgehog signaling

scientific article published on 21 June 2013

Craniofacial Development and Growth in Polycystic Kidney Disease

scientific article

Current topic: Hox genes: losses, gains and targets

scientific article published on November 1, 1992

Cytoplasmic plaque formation in hemidesmosome development is dependent on SoxF transcription factor function

scientific article

Death in the life of a tooth.

scientific article published on January 2004

Defining human mesenchymal and epithelial heterogeneity in response to oral inflammatory disease

scientific article published on 04 January 2021

Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth

scientific article published on 23 September 2020

Dental mesenchymal stem cells

scientific article

Dental stem cells for tooth regeneration and repair

scientific article published on September 2009

Detection of canine distemper virus in bone cells in the metaphyses of distemper-infected dogs.

scientific article published in July 1992

Development of a high-throughput replicon assay for the identification of respiratory syncytial virus inhibitors

scientific article published on 15 November 2013

Development of teeth in chick embryos after mouse neural crest transplantations

scientific article

Developmental genetics and early hominid craniodental evolution.

scientific article published in June 2001

Developmental stalling and organ-autonomous regulation of morphogenesis

scientific article published on 14 November 2011

Differential sensitivity to trypsin of human bone-derived cells in culture: Surface changes detected by partitioning in aqueous two-phase systems

article

Diseases of the tooth: the genetic and molecular basis of inherited anomalies affecting the dentition

scientific article published on 25 May 2012

Disrupted mitochondrial function in the Opa3L122P mouse model for Costeff Syndrome impairs skeletal integrity

scientific article published on 22 April 2016

Dissecting the genetic complexity of human 6p deletion syndromes by using a region-specific, phenotype-driven mouse screen

scientific article

Distinct roles of microRNAs in epithelium and mesenchyme during tooth development

scientific article published on 24 July 2012

Dlx homeobox gene family expression in osteoclasts.

scientific article

Dual origin of mesenchymal stem cells contributing to organ growth and repair

scientific article

Dual regulation of metalloproteinase expression in chondrocytes by Wnt-1-inducible signaling pathway protein 3/CCN6.

scientific article

Dynamic expression of chicken Sox2 and Sox3 genes in ectoderm induced to form neural tissue ⬇️

scientific article published on July 1, 1997

Ectoderm, endoderm, and the evolution of heterodont dentitions

scientific article published in June 2010

Edar/Eda interactions regulate enamel knot formation in tooth morphogenesis

scientific article

Evolution and development of teeth

scientific article (publication date: 2001)

Excess NF-κB induces ectopic odontogenesis in embryonic incisor epithelium.

scientific article published on 6 November 2014

Expanding the Oro-Dental and Mutational Spectra of Kabuki Syndrome and Expression of KMT2D and KDM6A in Human Tooth Germs.

scientific article

Expression analysis of candidate genes regulating successional tooth formation in the human embryo

scientific article

Expression and purification of biologically active IGF-binding proteins using the LCR/Mel expression system

scientific article published on January 2003

Expression and regulation of Lhx6 and Lhx7, a novel subfamily of LIM homeodomain encoding genes, suggests a role in mammalian head development

scientific article

Expression and regulation of hedgehog-interacting protein during early tooth development

scientific article published on January 2002

Expression and regulation of the Msx1 natural antisense transcript during development

scientific article

Expression of Axin2 indicates a role for canonical Wnt signaling in development of the crown and root during pre- and postnatal tooth development

scientific article published in January 2010

Expression of Claudin-3 during chick development

article

Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse

scientific article published on 27 March 2010

Expression of Sox genes in tooth development

scientific article published on January 2015

Expression of TNF-receptor-associated factor genes in murine tooth development

scientific article published on 01 May 2003

Expression of Wnt signalling pathway genes during tooth development.

scientific article published in July 1999

Expression of a human homeobox-containing gene is regulated by 1,25(OH)2D3 in bone cells

scientific article

Expression of claudins in murine tooth development.

scientific article published in January 2007

Expression of fibroblast growth factors (Fgfs) in murine tooth development.

scientific article published on 21 February 2011

Expression of the Hedgehog antagonists Rab23 and Slimb/βTrCP during mouse tooth development

article

Expression of the Scube3 epidermal growth factor-related gene during early embryonic development in the mouse.

scientific article published on 23 December 2006

Expression of the chicken Sox9 gene marks the onset of cartilage differentiation.

scientific article published on June 1996

Expression patterns of the homeobox gene, Hox-8, in the mouse embryo suggest a role in specifying tooth initiation and shape.

scientific article published on June 1992

Fgf-8 determines rostral-caudal polarity in the first branchial arch.

scientific article published in January 1999

Fish scale development: Hair today, teeth and scales yesterday?

scientific article

Formation of the tooth-bone interface.

scientific article published on 30 December 2009

Functional mesenchymal stem cell niches in adult mouse knee joint synovium in vivo

scientific article published on 01 May 2011

Gas1 is a modifier for holoprosencephaly and genetically interacts with sonic hedgehog

scientific journal article

Gene defect in ectodermal dysplasia implicates a death domain adapter in development

scientific article

Generation of multinucleated osteoclast-like cells from canine bone marrow: Effects of canine distemper virus ⬇️

scientific article published on July 1, 1995

Gestational changes in Ca2+ transport across rat placenta and mRNA for calbindin9K and Ca(2+)-ATPase

scientific article published on October 1, 1992

Glial origin of mesenchymal stem cells in a tooth model system

scientific article published on 27 July 2014

Granule cell development in the cerebellum is punctuated by changes in Sox gene expression

scientific article

HLA polymorphisms in Paget's disease of bone

scientific article published on 01 February 1994

Hierarchy revealed in the specification of three skeletal fates by Sox9 and Runx2.

scientific article published on October 2004

Homeobox genes and orofacial development.

scientific article published on January 1995

Hox-7 expression during murine craniofacial development.

scientific article published in October 1991

Immune modulation by apoptotic dental pulp stem cells in vivo

scientific article published in March 2018

In-vitro regulation of odontogenic gene expression in human embryonic tooth cells and SHED cells

scientific article

Independent functions and mechanisms for homeobox gene Barx1 in patterning mouse stomach and spleen

scientific journal article

Intergenic enhancers with distinct activities regulate Dlx gene expression in the mesenchyme of the branchial arches.

scientific article published on April 2004

Interleukin-6, IL-6 receptor, and IL-6 nuclear factor gene expression in paget's disease

article

Intrarenal cytokine mRNA expression and location in normal and IgA nephropathy tissue: TGF alpha, TGF beta, IGF 1, IL-4 and IL-6

scientific article published on 01 January 1994

Isolation and characterization of human and mouse ZIRTL, a member of the IRT1 family of transporters, mapping within the epidermal differentiation complex

scientific article

Isolation and expression of a new mouse homeobox gene

scientific article

Lack of analgesic efficacy of oral delta-9-tetrahydrocannabinol in postoperative pain

scientific article published in November 2003

Lateral tilt position for obese patients

scientific article published on 27 December 2008

Long-term survival in infantile malignant autosomal recessive osteopetrosis secondary to homozygous p.Arg526Gln mutation in CLCN7.

scientific article published on 14 March 2012

Low frequency electric and magnetic fields have different effects on the cell surface

scientific article published on 01 March 1988

Lrp4 modulates extracellular integration of cell signaling pathways in development

scientific article

Lrp4/Wise regulates palatal rugae development through Turing-type reaction-diffusion mechanisms

scientific article published in PLoS ONE

Lrp4: A novel modulator of extracellular signaling in craniofacial organogenesis.

scientific article published in December 2010

Making up the numbers: The molecular control of mammalian dental formula

scientific article published on 18 January 2010

Mesenchymal Cell Community Effect in Whole Tooth Bioengineering

scientific article published on 7 December 2016

Mesenchymal stem cells inhibit T-cell function through conserved induction of cellular stress

scientific article published on 14 March 2019

Misexpression of genes in mouse tooth germs using in vitro electroporation

scientific article published in January 2002

Molar tooth development in caspase-3 deficient mice.

scientific article published in January 2006

Molecular cloning, chromosomal mapping, and developmental expression of a novel protein tyrosine phosphatase-like gene.

scientific article published in December 1999

Molecular control of odontogenic patterning: positional dependent initiation and morphogenesis.

scientific article published in January 1998

Molecular genetics of tooth morphogenesis and patterning: the right shape in the right place

scientific article

Molecular programming of perivascular stem cell precursors

scientific article published on 12 November 2018

Mouse Hox-3.4: homeobox sequence and embryonic expression patterns compared with other members of the Hox gene network

scientific article published on 01 June 1990

Mouse models of tooth abnormalities

scientific article published on February 2008

Multiple postnatal craniofacial anomalies are characterized by conditional loss of polycystic kidney disease 2 (Pkd2).

scientific article published on 5 February 2013

NBR1 interacts with fasciculation and elongation protein zeta-1 (FEZ1) and calcium and integrin binding protein (CIB) and shows developmentally restricted expression in the neural tube

scientific article (publication date: 2002)

Neighbor of Brca1 gene (Nbr1) functions as a negative regulator of postnatal osteoblastic bone formation and p38 MAPK activity

scientific journal article

Neural crest and tooth morphogenesis.

scientific article

Neural crest contribution to mammalian tooth formation

scientific article published in June 2004

Non-apoptotic functions of caspase-7 during osteogenesis

scientific article published on 14 August 2014

Non-syndromic severe hypodontia caused by a novel frameshift insertion mutation in the homeobox of the MSX1 gene

scientific article published on 6 December 2016

Normal and abnormal dental development

scientific article

Notch2 protein distribution in human teeth under normal and pathological conditions

scientific article

Novel inhibitors of the alphavbeta3 integrin--lead identification strategy

scientific article published on 13 June 2009

Odontogenic epithelium induces similar molecular responses in chick and mouse mandibular mesenchyme

scientific article published on 01 December 1998

Opg, Rank, and Rankl in tooth development: co-ordination of odontogenesis and osteogenesis

scientific journal article

Optimisation of lithium-substituted bioactive glasses to tailor cell response for hard tissue repair

scientific article published on 9 February 2017

Oral lining mucosa development depends on mesenchymal microRNAs.

scientific article published on 14 December 2012

Organized Tooth-specific Cellular Differentiation Stimulated by BMP4

scientific article published on 01 July 2005

PKA regulatory subunit expression in tooth development

scientific article published on 19 April 2014

Paramyxoviruses and Paget's disease.

scientific article published in June 1993

Paramyxoviruses in Paget's disease

scientific article published on 01 February 1994

Patterning of the murine dentition by homeobox genes.

scientific article published in January 1998

Periodic stripe formation by a Turing mechanism operating at growth zones in the mammalian palate.

scientific article published on 19 February 2012

Perioperative nimodipine and postoperative analgesia.

scientific article published in February 2006

Perivascular Stem Cells at the Tip of Mouse Incisors Regulate Tissue Regeneration

scientific article published on 22 September 2015

Perivascular cells as mesenchymal stem cells

scientific article published on October 2010

Phenotype changes of oral epithelial stem cells after in vitro culture

scientific article published on 06 April 2020

Physiological implications of DLX homeoproteins in enamel formation.

scientific article published in September 2008

Preventing the loss of competence for neural induction: HGF/SF, L5 and Sox-2.

scientific article published on March 1997

Primary cilia regulate Shh activity in the control of molar tooth number

scientific journal article

Primary enamel knot cell death in Apaf-1 and caspase-9 deficient mice.

scientific article published on 20 October 2006

Promotion of natural tooth repair by small molecule GSK3 antagonists

scientific article published on 9 January 2017

Pulsed magnetic fields alter the cell surface

scientific article published on 01 April 1986

R-spondins/Lgrs expression in tooth development

scientific journal article

Reduced dosage of ERF causes complex craniosynostosis in humans and mice and links ERK1/2 signaling to regulation of osteogenesis

scientific article

Regeneration of teeth using stem cell-based tissue engineering

scientific article

Regional regulation of Filiform tongue papillae development by Ikkα/Irf6.

scientific article published on 15 June 2016

Regionalisation of early head ectoderm is regulated by endoderm and prepatterns the orofacial epithelium.

scientific article published in September 2004

Regulation and role of Sox9 in cartilage formation.

scientific article published in May 1999

Regulation of Mesenchymal Stem to Transit-Amplifying Cell Transition in the Continuously Growing Mouse Incisor

Regulation of Msx-1, Msx-2, Bmp-2 and Bmp-4 during foetal and postnatal mammary gland development

scientific journal article

Regulation of Reactionary Dentine Formation.

scientific article published in November 2017

Restriction of sonic hedgehog signalling during early tooth development

scientific article published on 19 May 2004

Ring1a/b polycomb proteins regulate the mesenchymal stem cell niche in continuously growing incisors.

scientific article published on 4 May 2012

Role of Dlx-1 and Dlx-2 genes in patterning of the murine dentition.

scientific article published in December 1997

Role of Islet1 in the patterning of murine dentition

scientific journal article

Role of the Dlx homeobox genes in proximodistal patterning of the branchial arches: mutations of Dlx-1, Dlx-2, and Dlx-1 and -2 alter morphogenesis of proximal skeletal and soft tissue structures derived from the first and second arches

scientific journal article

Satb2 haploinsufficiency phenocopies 2q32-q33 deletions, whereas loss suggests a fundamental role in the coordination of jaw development

scientific journal article

Scube1 is expressed during facial development in the mouse.

scientific article published in July 2009

Secretion of Shh by a Neurovascular Bundle Niche Supports Mesenchymal Stem Cell Homeostasis in the Adult Mouse Incisor.

scientific article published in July 2018

Secretion of shh by a neurovascular bundle niche supports mesenchymal stem cell homeostasis in the adult mouse incisor

scientific article published on February 2014

Sequence data obtained from patients with Paget's disease

scientific article published on 01 January 1994

Shape and volume of craniofacial cavities in intentional skull deformations.

scientific article

Skeletal analysis of the Fgfr3(P244R) mouse, a genetic model for the Muenke craniosynostosis syndrome.

scientific article

Sonic hedgehog in the pharyngeal endoderm controls arch pattern via regulation of Fgf8 in head ectoderm

scientific article published on 10 November 2006

Sonic hedgehog regulates epithelial proliferation and cell survival in the developing tooth germ

scientific article

Sonic hedgehog signaling and the developing tooth

scientific article

Sonic hedgehog signalling inhibits palatogenesis and arrests tooth development in a mouse model of the nevoid basal cell carcinoma syndrome

scientific article published on 24 April 2009

Sox gene expression during neuronal development.

scientific article published in August 1994

Spatial localisation of transcripts of the Hox-C6 gene.

scientific article

Spatio-temporal expression of Sox genes in murine palatogenesis.

scientific article published on 27 May 2016

Specification of the hypaxial musculature.

scientific article published in June 1998

Stem Cells in Tooth Development, Growth, Repair, and Regeneration

scientific article published on October 2015

Stem cell contributions to cementoblast differentiation in healthy periodontal ligament and periodontitis

scientific article published on 10 October 2020

Stem cell-based biological tooth repair and regeneration

scientific article

Stem cells and tooth tissue engineering

scientific article

Stem-cell-based tissue engineering of murine teeth.

scientific article published on July 2004

Studies of the growth of human bone-derived cells in culture using aqueous two-phase partition

article

Submicron imaging of soft-tissues using low-dose phase-contrast x-ray synchrotron microtomography with an iodine contrast agent.

scientific article published on 19 July 2014

Surface changes during the maturation of rat spermatozoa detected by aqueous two-phase partition.

scientific article published in December 1989

Surface heterogeneity of bovine sperm revealed by aqueous two-phase partition

scientific article published on 01 October 1991

Surface heterogeneity of rat sperm during maturation

scientific article published on 01 February 1992

TFII-I gene family during tooth development: candidate genes for tooth anomalies in Williams syndrome.

scientific article published in October 2007

TNF signalling in tooth development

scientific article published in October 2004

Temporospatial cell interactions regulating mandibular and maxillary arch patterning.

scientific article published in January 2000

Test-tube teeth.

scientific article published in August 2005

The Ectodysplasin and NFkappaB signalling pathways in odontogenesis.

scientific article

The LIM homeodomain transcription factors Lhx6 and Lhx7 are key regulators of mammalian dentition

scientific article published on 08 July 2009

The Mouse as a Developmental Model

article

The Shh signalling pathway in early tooth development.

scientific article published in July 1999

The Shh signalling pathway in tooth development: defects in Gli2 and Gli3 mutants

scientific article

The activation level of the TNF family receptor, Edar, determines cusp number and tooth number during tooth development.

scientific article published in April 2004

The application of aqueous two-phase partition to the study of chick limb mesenchymal diversification.

scientific article published in June 1986

The buccohypophyseal canal is an ancestral vertebrate trait maintained by modulation in sonic hedgehog signaling

scientific article (publication date: 28 March 2013)

The cutting-edge of mammalian development; how the embryo makes teeth

scientific article published on July 2004

The dystrotelin, dystrophin and dystrobrevin superfamily: new paralogues and old isoforms.

scientific article

The effect of tunicamycin on cell-surface changes associated with development and differentiation ofDictyostelium discoideum

article

The homeobox gene Hox 7.1 has specific regional and temporal expression patterns during early murine craniofacial embryogenesis, especially tooth development in vivo and in vitro.

scientific article published in February 1991

The incorporation of glycolipids with defined carbohydrate sequence into liposomes and the effects on partition in aqueous two-phase systems

scientific article published on 01 May 1984

The karyotype of Alligator mississippiensis, and chromosomal mapping of the ZFY/X homologue, Zfc

scientific article published on 01 December 1994

The molecular anatomy of Hox gene expression

scientific article

The mouse as a developmental model

scientific article

The origin of the stapes and relationship to the otic capsule and oval window

scientific article published on 2 August 2012

The partition of charged liposomes in aqueous two-phase systems

scientific article published in 1985

The role of Irf6 in tooth epithelial invagination.

scientific article published on 14 February 2012

The role of effectors of the activin signalling pathway, activin receptors IIA and IIB, and Smad2, in patterning of tooth development

scientific journal article

The small molecule CLP257 does not modify activity of the K+-Cl- co-transporter KCC2 but does potentiate GABAA receptor activity.

scientific article

The smallest teeth in the world are caused by mutations in the PCNT gene

article

The stomach mesenchymal transcription factor Barx1 specifies gastric epithelial identity through inhibition of transient Wnt signaling

scientific journal article

The tooth -- a treasure chest of stem cells.

scientific article published on October 2013

Tissue engineering of teeth using adult stem cells.

scientific article published in February 2005

Tooth Repair and Regeneration

scientific article published on 25 October 2018

Tooth agenesis: from molecular genetics to molecular dentistry.

scientific article published on July 2008

Tooth and jaw: molecular mechanisms of patterning in the first branchial arch

scientific article

Tooth development is independent of a Hox patterning programme.

scientific article published in November 2002

Traf6 is essential for murine tooth cusp morphogenesis

scientific journal article

Transformation of tooth type induced by inhibition of BMP signaling

scientific article

Tricho-Rhino-Phalangeal Syndrome with Supernumerary Teeth

scientific article published on 01 November 2008

Upregulation of c-Fos protooncogene expression in pagetic osteoclasts

scientific article published on 01 August 1994

WNT10A mutation results in severe tooth agenesis in a family of three sisters

scientific article published on 21 June 2018

Wnt signaling in the murine diastema

scientific article (publication date: August 2012)

Wnt signaling regulates pulp volume and dentin thickness

scientific article

Wnt/Shh interactions regulate ectodermal boundary formation during mammalian tooth development

scientific journal article

[30] Surface changes during growth and development of slime molds

article

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