List of works - Timothy E Shutt

A compendium of human mitochondrial gene expression machinery with links to disease.

scientific article

A synthetic peptide rescues rat cortical neurons from anesthetic-induced cell death, perturbation of growth and synaptic assembly

scientific article published on 25 February 2021

Aberrant Mitochondrial Morphology and Function in the BTBR Mouse Model of Autism Is Improved by Two Weeks of Ketogenic Diet

scientific article published on 05 May 2020

Advances Towards Therapeutic Approaches for mtDNA Disease

scientific article published on 01 January 2019

Characterization of a novel variant in the HR1 domain of MFN2 in a patient with ataxia, optic atrophy and sensorineural hearing loss

scientific article published in 2022

Characterization of a novel variant in the HR1 domain of MFN2 in a patient with ataxia, optic atrophy and sensorineural hearing loss

scientific article published in 2021

Characterization of the C584R variant in the mtDNA depletion syndrome gene FBXL4, reveals a novel role for FBXL4 as a regulator of mitochondrial fusion

scientific article published on 20 August 2019

Core human mitochondrial transcription apparatus is a regulated two-component system in vitro.

scientific article

Expanding the mitochondrial interactome.

scientific article published on January 2007

Homologs of mitochondrial transcription factor B, sparsely distributed within the eukaryotic radiation, are likely derived from the dimethyladenosine methyltransferase of the mitochondrial endosymbiont

scientific article published on 13 March 2006

MSTO1 mutations cause mtDNA depletion, manifesting as muscular dystrophy with cerebellar involvement

scientific article published on 29 August 2019

Mitochondrial Dynamics in Signaling and Disease

scientific article published on 27 July 2019

Mitochondrial Ribosomal Protein L12 selectively associates with human mitochondrial RNA polymerase to activate transcription ⬇️

scientific article published on October 14, 2011

Neuropathy due to impaired axonal transport of non-fragmented mitochondria in MYH14 mutation carriers-Authors' reply

scientific article published on 17 October 2019

ROMO1 is an essential redox-dependent regulator of mitochondrial dynamics.

scientific article published on 28 January 2014

SS-31 Peptide Reverses the Mitochondrial Fragmentation Present in Fibroblasts From Patients With DCMA, a Mitochondrial Cardiomyopathy

scientific article published on 15 November 2019

Skeletal Phenotypes Due to Abnormalities in Mitochondrial Protein Homeostasis and Import

scientific article published on 06 November 2020

Staying cool in difficult times: Mitochondrial dynamics, quality control and the stress response ⬇️

scientific article published on 07 June 2012

The Keap1-Nrf2 Stress Response Pathway Promotes Mitochondrial Hyperfusion Through Degradation of the Mitochondrial Fission Protein Drp1.

scientific article published on 11 May 2017

The R941L mutation in MYH14 disrupts mitochondrial fission and associates with peripheral neuropathy

scientific article published on 21 June 2019

The intracellular redox state is a core determinant of mitochondrial fusion ⬇️

scientific article published on September 4, 2012

The mitochondrial division inhibitor Mdivi-1 rescues mammalian neurons from anesthetic-induced cytotoxicity

scientific article published on 24 March 2016

Tissue Specific Impacts of a Ketogenic Diet on Mitochondrial Dynamics in the BTBRT+tf/j Mouse.

scientific article published on 27 December 2016

is a mitochondrial disease gene causing skeletal dysplasia, cataracts, and white matter changes

article

List of works by Timothy E Shutt

A compendium of human mitochondrial gene expression machinery with links to disease.

A synthetic peptide rescues rat cortical neurons from anesthetic-induced cell death, perturbation of growth and synaptic assembly

Aberrant Mitochondrial Morphology and Function in the BTBR Mouse Model of Autism Is Improved by Two Weeks of Ketogenic Diet

Advances Towards Therapeutic Approaches for mtDNA Disease

Characterization of a novel variant in the HR1 domain of MFN2 in a patient with ataxia, optic atrophy and sensorineural hearing loss

Characterization of a novel variant in the HR1 domain of MFN2 in a patient with ataxia, optic atrophy and sensorineural hearing loss

Characterization of the C584R variant in the mtDNA depletion syndrome gene FBXL4, reveals a novel role for FBXL4 as a regulator of mitochondrial fusion

Core human mitochondrial transcription apparatus is a regulated two-component system in vitro.

Expanding the mitochondrial interactome.

Homologs of mitochondrial transcription factor B, sparsely distributed within the eukaryotic radiation, are likely derived from the dimethyladenosine methyltransferase of the mitochondrial endosymbiont

MSTO1 mutations cause mtDNA depletion, manifesting as muscular dystrophy with cerebellar involvement

Mitochondrial Dynamics in Signaling and Disease

Mitochondrial Ribosomal Protein L12 selectively associates with human mitochondrial RNA polymerase to activate transcription ⬇️

Neuropathy due to impaired axonal transport of non-fragmented mitochondria in MYH14 mutation carriers-Authors' reply

ROMO1 is an essential redox-dependent regulator of mitochondrial dynamics.

SS-31 Peptide Reverses the Mitochondrial Fragmentation Present in Fibroblasts From Patients With DCMA, a Mitochondrial Cardiomyopathy

Skeletal Phenotypes Due to Abnormalities in Mitochondrial Protein Homeostasis and Import

Staying cool in difficult times: Mitochondrial dynamics, quality control and the stress response ⬇️

The Keap1-Nrf2 Stress Response Pathway Promotes Mitochondrial Hyperfusion Through Degradation of the Mitochondrial Fission Protein Drp1.

The R941L mutation in MYH14 disrupts mitochondrial fission and associates with peripheral neuropathy

The intracellular redox state is a core determinant of mitochondrial fusion ⬇️

The mitochondrial division inhibitor Mdivi-1 rescues mammalian neurons from anesthetic-induced cytotoxicity

Tissue Specific Impacts of a Ketogenic Diet on Mitochondrial Dynamics in the BTBRT+tf/j Mouse.

is a mitochondrial disease gene causing skeletal dysplasia, cataracts, and white matter changes