List of works - David J Price

-Lineage Cells Increase Their Contribution to Visual Thalamic Nuclei during Murine Embryogenesis If They Are Homozygous or Heterozygous for Loss of Function

scientific article published on 01 September 2018

2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline.

scientific article published on 15 June 2015

A conditional Pax6 depletion study with no morphological effect on the adult mouse corneal epithelium

scientific article published on 05 October 2018

Abnormal positioning of diencephalic cell types in neocortical tissue in the dorsal telencephalon of mice lacking functional Gli3.

scientific article published on September 2006

Analysis of axon guidance defects at the optic chiasm in heparan sulphate sulphotransferase compound mutant mice

scientific article published on 26 September 2011

Analysis of compound heterozygotes reveals that the mouse floxed Pax6 (tm1Ued) allele produces abnormal eye phenotypes.

scientific article published on 30 May 2016

Analysis of early ventral telencephalic defects in mice lacking functional Gli3 protein

scientific journal article

Building brains in a dish: Prospects for growing cerebral organoids from stem cells

scientific article

Cell-autonomous repression of Shh by transcription factor Pax6 regulates diencephalic patterning by controlling the central diencephalic organizer.

scientific article published on 28 August 2014

Comparison of two related lines of tauGFP transgenic mice designed for lineage tracing

scientific article

Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization

scientific article published on 3 January 2007

DISC1 regulates N-methyl-D-aspartate receptor dynamics: abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness

scientific article published on 06 September 2018

Defect of tyrosine hydroxylase-immunoreactive neurons in the brains of mice lacking the transcription factor Pax6

scientific article published on 01 September 2000

Determination of the migratory capacity of embryonic cortical cells lacking the transcription factor Pax-6 ⬇️

scientific article published on December 1, 1997

Disruption of early events in thalamocortical tract formation in mice lacking the transcription factors Pax6 or Foxg1.

scientific article published in October 2002

Early emergence of cortical interneuron diversity in the mouse embryo.

scientific article published on 22 February 2018

Etr-r3/mNapor, encoding an ELAV-type RNA binding protein, is expressed in differentiating cells in the developing rodent forebrain

scientific article published in March 2002

Evaluation of the mouse TgTP6.3 tauGFP transgene as a lineage marker in chimeras

scientific article published in January 2005

Expression of Barhl2 and its relationship with Pax6 expression in the forebrain of the mouse embryo

scientific article

FGF8 morphogen gradients are differentially regulated by heparan sulphotransferases Hs2st and Hs6st1 in the developing brain

scientific article published on 20 November 2017

Foxg1 is required to limit the formation of ciliary margin tissue and Wnt/β-catenin signalling in the developing nasal retina of the mouse.

scientific article published on 24 April 2013

Functional conservation of Pax6 regulatory elements in humans and mice demonstrated with a novel transgenic reporter mouse

scientific article published on 4 May 2006

Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning.

scientific article published on 04 October 2012

Gli3 controls the onset of cortical neurogenesis by regulating the radial glial cell cycle through expression

scholarly article by Kerstin Hasenpusch-Theil published in August 2018

Gli3 is required autonomously for dorsal telencephalic cells to adopt appropriate fates during embryonic forebrain development

scientific article published on 24 December 2008

Heparan sulfate sugar modifications mediate the functions of slits and other factors needed for mouse forebrain commissure development.

scientific article published in February 2011

Heparan sulfotransferases Hs6st1 and Hs2st keep Erk in check for mouse corpus callosum development

scientific article published on February 2014

Heparan sulphation patterns generated by specific heparan sulfotransferase enzymes direct distinct aspects of retinal axon guidance at the optic chiasm.

scientific article published in June 2006

Identification of genomic regions regulating Pax6 expression in embryonic forebrain using YAC reporter transgenic mouse lines

scientific article

Identifying GFP-transgenic animals by flashlight

scientific article published on 01 March 2003

Interactions between TrkB signaling and serotonin excess in the developing murine somatosensory cortex: a role in tangential and radial organization of thalamocortical axons.

scientific article

Junk DNA Used in Cerebral Cortical Evolution.

scientific article published in June 2016

Lateral cortical Cdca7 expression levels are regulated by Pax6 and influence the production of intermediate progenitors

scientific article

Long-range downstream enhancers are essential for Pax6 expression

scientific article published on 30 August 2006

Loss of Gli3 enhances the viability of embryonic telencephalic cells in vitro.

scientific article published on September 2005

MicroRNA-92b regulates the development of intermediate cortical progenitors in embryonic mouse brain.

scientific article published on 8 April 2013

Mouse models of telencephalic development.

scientific article

Newly identified patterns of Pax2 expression in the developing mouse forebrain

scientific article

Normal ventral telencephalic expression of Pax6 is required for normal development of thalamocortical axons in embryonic mice.

scientific article published on 05 June 2009

Novel lines of Pax6-/- embryonic stem cells exhibit reduced neurogenic capacity without loss of viability

scientific article

Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance

scientific article

Pax6 Lengthens G1 Phase and Decreases Oscillating Cdk6 Levels in Murine Embryonic Cortical Progenitors

scientific article published on 15 November 2018

Pax6 is required to regulate the cell cycle and the rate of progression from symmetrical to asymmetrical division in mammalian cortical progenitors.

scientific article published in January 2002

Pax6 limits the competence of developing cerebral cortical cells to respond to inductive intercellular signals

scientific article published in 2022

Pax6; a pleiotropic player in development.

scientific article

Penetrance of eye defects in mice heterozygous for mutation of Gli3 is enhanced by heterozygous mutation of Pax6.

scientific article

Positive autoregulation of the transcription factor Pax6 in response to increased levels of either of its major isoforms, Pax6 or Pax6(5a), in cultured cells

scientific article published on 25 May 2006

Regulation of cerebral cortical neurogenesis by the Pax6 transcription factor

scientific article published on 10 March 2015

Regulation of the Pax6 : Pax6(5a) mRNA ratio in the developing mammalian brain.

scientific article

Role of Pax6 in forebrain regionalization

scientific article

Specific modification of heparan sulphate is required for normal cerebral cortical development

scientific article

Steerable-filter based quantification of axonal populations at the developing optic chiasm reveal significant defects in Slit2 −/− as well as Slit1 −/− Slit2 −/− embryos ⬇️

scientific article published on January 15, 2013

Target-derived neurotrophic factors regulate the death of developing forebrain neurons after a change in their trophic requirements.

scientific article

The Gli3 hypomorphic mutation Pdn causes selective impairment in the growth, patterning, and axon guidance capability of the lateral ganglionic eminence

scientific journal article

The Transcription Factor Foxg1 Promotes Optic Fissure Closure in the Mouse by Suppressing Wnt8b in the Nasal Optic Stalk

scientific article published on 20 July 2017

The expression and activity of β-catenin in the thalamus and its projections to the cerebral cortex in the mouse embryo.

scientific article

The generation of superficial cortical layers is regulated by levels of the transcription factor Pax6

scientific article

The importance of combinatorial gene expression in early Mammalian thalamic patterning and thalamocortical axonal guidance.

scientific article published on 15 March 2012

The molecular and cellular signatures of the mouse eminentia thalami support its role as a signalling centre in the developing forebrain

scientific article

The organization of corticocortical projections from area 17 to area 18 of the cat's visual cortex.

scientific article

The role of Pax6 in forebrain development.

scientific article published on August 2011

The role of neurotrophin receptors in female germ-cell survival in mouse and human.

scientific article published on 24 September 2003

The transcription factor Foxg1 regulates telencephalic progenitor proliferation cell autonomously, in part by controlling Pax6 expression levels

scientific article

The transcription factor Foxg1 regulates the competence of telencephalic cells to adopt subpallial fates in mice

scientific article published on February 2010

The transcription factor Pax6 is required for development of the diencephalic dorsal midline secretory radial glia that form the subcommissural organ.

scientific article published on December 2001

The winged helix transcription factor Foxg1 facilitates retinal ganglion cell axon crossing of the ventral midline in the mouse

scientific journal article

Tissue-Specific Actions of Pax6 on Proliferation and Differentiation Balance in Developing Forebrain Are Foxg1 Dependent

scientific article published on 22 November 2018

Wnt/β-catenin signaling is disrupted in the extra-toes (Gli3(Xt/Xt) ) mutant from early stages of forebrain development, concomitant with anterior neural plate patterning defects.

scientific article published in June 2011

List of works by David J Price

-Lineage Cells Increase Their Contribution to Visual Thalamic Nuclei during Murine Embryogenesis If They Are Homozygous or Heterozygous for Loss of Function

2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline.

A conditional Pax6 depletion study with no morphological effect on the adult mouse corneal epithelium

Abnormal positioning of diencephalic cell types in neocortical tissue in the dorsal telencephalon of mice lacking functional Gli3.

Analysis of axon guidance defects at the optic chiasm in heparan sulphate sulphotransferase compound mutant mice

Analysis of compound heterozygotes reveals that the mouse floxed Pax6 (tm1Ued) allele produces abnormal eye phenotypes.

Analysis of early ventral telencephalic defects in mice lacking functional Gli3 protein

Building brains in a dish: Prospects for growing cerebral organoids from stem cells

Cell-autonomous repression of Shh by transcription factor Pax6 regulates diencephalic patterning by controlling the central diencephalic organizer.

Comparison of two related lines of tauGFP transgenic mice designed for lineage tracing

Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization

DISC1 regulates N-methyl-D-aspartate receptor dynamics: abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness

Defect of tyrosine hydroxylase-immunoreactive neurons in the brains of mice lacking the transcription factor Pax6

Determination of the migratory capacity of embryonic cortical cells lacking the transcription factor Pax-6 ⬇️

Disruption of early events in thalamocortical tract formation in mice lacking the transcription factors Pax6 or Foxg1.

Early emergence of cortical interneuron diversity in the mouse embryo.

Etr-r3/mNapor, encoding an ELAV-type RNA binding protein, is expressed in differentiating cells in the developing rodent forebrain

Evaluation of the mouse TgTP6.3 tauGFP transgene as a lineage marker in chimeras

Expression of Barhl2 and its relationship with Pax6 expression in the forebrain of the mouse embryo

FGF8 morphogen gradients are differentially regulated by heparan sulphotransferases Hs2st and Hs6st1 in the developing brain

Foxg1 is required to limit the formation of ciliary margin tissue and Wnt/β-catenin signalling in the developing nasal retina of the mouse.

Functional conservation of Pax6 regulatory elements in humans and mice demonstrated with a novel transgenic reporter mouse

Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning.

Gli3 controls the onset of cortical neurogenesis by regulating the radial glial cell cycle through expression

Gli3 is required autonomously for dorsal telencephalic cells to adopt appropriate fates during embryonic forebrain development

Heparan sulfate sugar modifications mediate the functions of slits and other factors needed for mouse forebrain commissure development.

Heparan sulfotransferases Hs6st1 and Hs2st keep Erk in check for mouse corpus callosum development

Heparan sulphation patterns generated by specific heparan sulfotransferase enzymes direct distinct aspects of retinal axon guidance at the optic chiasm.

Identification of genomic regions regulating Pax6 expression in embryonic forebrain using YAC reporter transgenic mouse lines

Identifying GFP-transgenic animals by flashlight

Interactions between TrkB signaling and serotonin excess in the developing murine somatosensory cortex: a role in tangential and radial organization of thalamocortical axons.

Junk DNA Used in Cerebral Cortical Evolution.

Lateral cortical Cdca7 expression levels are regulated by Pax6 and influence the production of intermediate progenitors

Long-range downstream enhancers are essential for Pax6 expression

Loss of Gli3 enhances the viability of embryonic telencephalic cells in vitro.

MicroRNA-92b regulates the development of intermediate cortical progenitors in embryonic mouse brain.

Mouse models of telencephalic development.

Newly identified patterns of Pax2 expression in the developing mouse forebrain

Normal ventral telencephalic expression of Pax6 is required for normal development of thalamocortical axons in embryonic mice.

Novel lines of Pax6-/- embryonic stem cells exhibit reduced neurogenic capacity without loss of viability

Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance

Pax6 Lengthens G1 Phase and Decreases Oscillating Cdk6 Levels in Murine Embryonic Cortical Progenitors

Pax6 is required to regulate the cell cycle and the rate of progression from symmetrical to asymmetrical division in mammalian cortical progenitors.

Pax6 limits the competence of developing cerebral cortical cells to respond to inductive intercellular signals

Pax6; a pleiotropic player in development.

Penetrance of eye defects in mice heterozygous for mutation of Gli3 is enhanced by heterozygous mutation of Pax6.

Positive autoregulation of the transcription factor Pax6 in response to increased levels of either of its major isoforms, Pax6 or Pax6(5a), in cultured cells

Regulation of cerebral cortical neurogenesis by the Pax6 transcription factor

Regulation of the Pax6 : Pax6(5a) mRNA ratio in the developing mammalian brain.

Role of Pax6 in forebrain regionalization

Specific modification of heparan sulphate is required for normal cerebral cortical development

Steerable-filter based quantification of axonal populations at the developing optic chiasm reveal significant defects in Slit2 −/− as well as Slit1 −/− Slit2 −/− embryos ⬇️

Target-derived neurotrophic factors regulate the death of developing forebrain neurons after a change in their trophic requirements.

The Gli3 hypomorphic mutation Pdn causes selective impairment in the growth, patterning, and axon guidance capability of the lateral ganglionic eminence

The Transcription Factor Foxg1 Promotes Optic Fissure Closure in the Mouse by Suppressing Wnt8b in the Nasal Optic Stalk

The expression and activity of β-catenin in the thalamus and its projections to the cerebral cortex in the mouse embryo.

The generation of superficial cortical layers is regulated by levels of the transcription factor Pax6

The importance of combinatorial gene expression in early Mammalian thalamic patterning and thalamocortical axonal guidance.

The molecular and cellular signatures of the mouse eminentia thalami support its role as a signalling centre in the developing forebrain

The organization of corticocortical projections from area 17 to area 18 of the cat's visual cortex.

The role of Pax6 in forebrain development.

The role of neurotrophin receptors in female germ-cell survival in mouse and human.

The transcription factor Foxg1 regulates telencephalic progenitor proliferation cell autonomously, in part by controlling Pax6 expression levels

The transcription factor Foxg1 regulates the competence of telencephalic cells to adopt subpallial fates in mice

The transcription factor Pax6 is required for development of the diencephalic dorsal midline secretory radial glia that form the subcommissural organ.

The winged helix transcription factor Foxg1 facilitates retinal ganglion cell axon crossing of the ventral midline in the mouse

Tissue-Specific Actions of Pax6 on Proliferation and Differentiation Balance in Developing Forebrain Are Foxg1 Dependent

Wnt/β-catenin signaling is disrupted in the extra-toes (Gli3(Xt/Xt) ) mutant from early stages of forebrain development, concomitant with anterior neural plate patterning defects.