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List of works by James Wason

A Bayesian adaptive design for biomarker trials with linked treatments

scientific article published on 11 August 2015

A Review of Bayesian Perspectives on Sample Size Derivation for Confirmatory Trials

scientific article published on 22 March 2021

A comparison of Bayesian adaptive randomization and multi-stage designs for multi-arm clinical trials

scientific article

A general framework for two-stage analysis of genome-wide association studies and its application to case-control studies ⬇️

scientific article published on May 4, 2012

A latent variable model for improving inference in trials assessing the effect of dose on toxicity and composite efficacy endpoints

scientific article published on 25 February 2019

A multi-stage drop-the-losers design for multi-arm clinical trials.

scientific article published on 16 September 2014

A novel nano-iron supplement to safely combat iron deficiency and anaemia in young children: The IHAT-GUT double-blind, randomised, placebo-controlled trial protocol

scientific article published on 11 October 2018

A review of statistical designs for improving the efficiency of phase II studies in oncology.

scientific article published on 31 May 2015

Accelerated BEP: a phase I trial of dose-dense BEP for intermediate and poor prognosis metastatic germ cell tumour.

scientific article

Adaptive designs for clinical trials assessing biomarker-guided treatment strategies.

scientific article published on 25 March 2014

Adaptive designs in clinical trials: why use them, and how to run and report them.

scientific article published on 28 February 2018

Admissible multiarm stepped-wedge cluster randomized trial designs

scientific article published on 6 November 2018

Admissible two-stage designs for phase II cancer clinical trials that incorporate the expected sample size under the alternative hypothesis.

scientific article

An adaptive design for updating the threshold value of a continuous biomarker.

scientific article published on 14 July 2016

An optimised multi-arm multi-stage clinical trial design for unknown variance.

scientific article

Analysis of responder-based endpoints: improving power through utilising continuous components

scientific article published on 25 May 2020

Anti-VEGF intervention in neovascular AMD: benefits and risks restated as natural frequencies

scientific article published on 14 June 2019

Blinded and unblinded sample size reestimation in crossover trials balanced for period

scientific article published on 03 August 2018

Blinded and unblinded sample size reestimation procedures for stepped-wedge cluster randomized trials

scientific article published on 03 August 2018

Comment on: Month of birth and risk of multiple sclerosis: confounding and adjustments

scientific article published on 10 April 2014

Comparison of multimarker logistic regression models, with application to a genomewide scan of schizophrenia.

scientific article

Confounding in association studies: month of birth and multiple sclerosis

scientific article

Confounding underlies the apparent month of birth effect in multiple sclerosis

scientific article

Controlling type I error rates in multi-arm clinical trials: A case for the false discovery rate

scientific article published on 12 August 2020

Correcting for multiple-testing in multi-arm trials: is it necessary and is it done?

scientific article published on 17 September 2014

Costs and staffing resource requirements for adaptive clinical trials: quantitative and qualitative results from the Costing Adaptive Trials project

scientific article published on 26 October 2021

Design of experiments for a confirmatory trial of precision medicine

scientific article published on 01 March 2019

Design of telehealth trials--introducing adaptive approaches

scientific article published on 16 September 2014

Development process of a consensus-driven CONSORT extension for randomised trials using an adaptive design

article by Munyaradzi Dimairo et al published 16 November 2018 in BMC Medicine

Effect of sleep deprivation and exercise on reaction threshold in adults with peanut allergy: A randomized controlled study

scientific article published on 15 July 2019

Efficient analysis of time-to-event endpoints when the event involves a continuous variable crossing a threshold

scientific article published on 01 September 2020

Employing a latent variable framework to improve efficiency in composite endpoint analysis

scientific article published on 24 November 2020

Endoplasmic reticulum stress, unfolded protein response and development of colon adenocarcinoma

scientific article published on 25 May 2016

Evaluation of PR3-ANCA Status After Rituximab for ANCA-Associated Vasculitis

scientific article published on 01 August 2019

Evaluation of multisystemic therapy pilot services in Services for Teens Engaging in Problem Sexual Behaviour (STEPS-B): study protocol for a randomized controlled trial

scientific article

Evaluation of multisystemic therapy pilot services in the Systemic Therapy for At Risk Teens (START) trial: study protocol for a randomised controlled trial

scientific article published on 20 August 2013

Familywise error control in multi-armed response-adaptive trials

scientific article published on 03 April 2019

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

scientific article

Group sequential crossover trial designs with strong control of the familywise error rate

scientific article published on 02 October 2018

Group sequential designs for stepped-wedge cluster randomised trials.

scientific article

HLA associations in South Asian multiple sclerosis.

scientific article published on 28 April 2015

Healthy Campus Trial: a multiphase optimization strategy (MOST) fully factorial trial to optimize the smartphone cognitive behavioral therapy (CBT) app for mental health promotion among university students: study protocol for a randomized controlled

scientific article published on 4 July 2018

Identifying combined design and analysis procedures in two‐stage trials with a binary end point ⬇️

scientific article published on July 11, 2012

Imaging biomarker roadmap for cancer studies ⬇️

scientific article

Improving outcomes in adults with epilepsy and intellectual disability (EpAID) using a nurse-led intervention: study protocol for a cluster randomised controlled trial.

scientific article

Improving phase II oncology trials using best observed RECIST response as an endpoint by modelling continuous tumour measurements

scientific article published on 28 August 2017

Improving the analysis of composite endpoints in rare disease trials.

scientific article published on 22 May 2018

Improving the power of clinical trials of rheumatoid arthritis by using data on continuous scales when analysing response rates: an application of the augmented binary method

scientific article

Minimizing the Maximum Expected Sample Size in Two-Stage Phase II Clinical Trials with Continuous Outcomes ⬇️

scientific article published on January 1, 2012

Multi-arm multi-stage trials can improve the efficiency of finding effective treatments for stroke: a case study

scientific article published on 27 November 2018

Multi-armed Bandit Models for the Optimal Design of Clinical Trials: Benefits and Challenges ⬇️

scientific article published on January 2015

Multisystemic therapy compared with management as usual for adolescents at risk of offending: the START II RCT

scientific article published on 03 June 2020

Multisystemic therapy versus management as usual in the treatment of adolescent antisocial behaviour (START): a pragmatic, randomised controlled, superiority trial. ⬇️

scientific article published on 4 January 2018

Noninterventional statistical comparison of BTS and CHEST guidelines for size and severity in primary pneumothorax.

scientific article published on 18 March 2015

Prospective study evaluating the relative sensitivity of 18F-NaF PET/CT for detecting skeletal metastases from renal cell carcinoma in comparison to multidetector CT and 99mTc-MDP bone scintigraphy, using an adaptive trial design

scientific article

Reducing sample sizes in two-stage phase II cancer trials by using continuous tumour shrinkage end-points.

scientific article published on 14 January 2011

Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor

scientific article published on 18 March 2009

Response-adaptive designs for binary responses: How to offer patient benefit while being robust to time trends?

scientific article published on 19 December 2017

Response-adaptive randomization for multi-arm clinical trials using the forward looking Gittins index rule.

scientific article published on 22 June 2015

Some recommendations for multi-arm multi-stage trials

scientific article published on 28 November 2013

Stepped wedge cluster randomized controlled trial designs: a review of reporting quality and design features

scientific article

The choice of test in phase II cancer trials assessing continuous tumour shrinkage when complete responses are expected ⬇️

scientific article published on December 16, 2011

The endoplasmic reticulum stress marker CHOP predicts survival in malignant mesothelioma.

scientific article published on 14 February 2013

The impact of an epilepsy nurse competency framework on the costs of supporting adults with epilepsy and intellectual disability: findings from the EpAID study

scientific article published on 08 August 2019

The longitudinal effect of ejaculation on seminal vesicle fluid volume and whole-prostate ADC as measured on prostate MRI.

scientific article published on 4 July 2017

The power of phase II end-points for different possible mechanisms of action of an experimental treatment

scientific article published on 31 March 2015

To add or not to add a new treatment arm to a multiarm study: A decision-theoretic framework

scientific article published on 21 May 2019

Training nurses in a competency framework to support adults with epilepsy and intellectual disability: the EpAID cluster RCT.

scientific article published in February 2018

Two-stage phase II oncology designs using short-term endpoints for early stopping.

scientific article published on 2 June 2015

Use of an embedded, micro-randomised trial to investigate non-compliance in telehealth interventions.

scientific article published on 11 March 2016

Using continuous data on tumour measurements to improve inference in phase II cancer studies.

scientific article

What role for genetics in the prediction of multiple sclerosis?

scientific article

When to keep it simple - adaptive designs are not always useful

scientific article published on 02 August 2019

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