List of works -

ABCG1 is involved in vitamin E efflux

scientific article published in December 2014

ATP-binding cassette transporter A1 in lipoprotein metabolism and atherosclerosis: a new piece of the complex puzzle

scientific article

ATP-binding cassette transporter A1: key player in cardiovascular and metabolic disease at local and systemic level

scientific article published on August 2014

ATP-binding cassette transporters A1 and G1, HDL metabolism, cholesterol efflux, and inflammation: important targets for the treatment of atherosclerosis

scientific article published on May 2011

Abca1 deficiency protects the heart against myocardial infarction-induced injury

scientific article published on 11 June 2016

Absence of HDL cholesteryl ester uptake in mice via SR-BI impairs an adequate adrenal glucocorticoid-mediated stress response to fasting

scientific article

Activation of human platelets by misfolded proteins

scientific article published on 17 May 2007

Activation of the nuclear receptor PXR decreases plasma LDL-cholesterol levels and induces hepatic steatosis in LDL receptor knockout mice

scientific article published in January 2009

Adenovirus-mediated hepatic overexpression of scavenger receptor class B type I accelerates chylomicron metabolism in C57BL/6J mice

scientific article

Adrenal-specific scavenger receptor BI deficiency induces glucocorticoid insufficiency and lowers plasma very-low-density and low-density lipoprotein levels in mice

scientific article published on 29 November 2012

Adrenocortical LDL receptor function negatively influences glucocorticoid output

scientific article published on July 2015

Aorta of ApoE-deficient mice responds to atherogenic stimuli by a prelesional increase and subsequent decrease in the expression of antioxidant enzymes

scientific article

Augmented atherogenesis in LDL receptor deficient mice lacking both macrophage ABCA1 and ApoE

scientific article (publication date: 2011)

Bone marrow-derived multidrug resistance protein ABCB4 protects against atherosclerotic lesion development in LDL receptor knockout mice

scientific article published on 17 May 2007

Both hepatic and extrahepatic ABCA1 have discrete and essential functions in the maintenance of plasma high-density lipoprotein cholesterol levels in vivo

scientific article published on 28 August 2006

Coexistence of foam cells and hypocholesterolemia in mice lacking the ABC transporters A1 and G1.

scientific article published on 25 October 2007

Combined deletion of macrophage ABCA1 and ABCG1 leads to massive lipid accumulation in tissue macrophages and distinct atherosclerosis at relatively low plasma cholesterol levels

scientific article published on 15 November 2007

Correction: Effects of Deletion of Macrophage ABCA7 on Lipid Metabolism and the Development of Atherosclerosis in the Presence and Absence of ABCA1.

scientific article published on 24 May 2012

Cyclosporin A decreases apolipoprotein E secretion from human macrophages via a protein phosphatase 2B-dependent and ATP-binding cassette transporter A1 (ABCA1)-independent pathway

scientific article

Deletion of the high-density lipoprotein receptor scavenger receptor BI in mice modulates thrombosis susceptibility and indirectly affects platelet function by elevation of plasma free cholesterol

scientific article

Diet induced regulation of genes involved in cholesterol metabolism in rat liver parenchymal and Kupffer cells

scientific journal article

Differential effects of scavenger receptor BI deficiency on lipid metabolism in cells of the arterial wall and in the liver

scientific article published on 14 March 2003

Downregulation of platelet responsiveness upon contact with LDL by the protein-tyrosine phosphatases SHP-1 and SHP-2.

scientific article

Dual role for scavenger receptor class B, type I on bone marrow-derived cells in atherosclerotic lesion development

scientific article

Effects of deletion of macrophage ABCA7 on lipid metabolism and the development of atherosclerosis in the presence and absence of ABCA1

scientific article (publication date: 2012)

Elimination of macrophages drives LXR-induced regression both in initial and advanced stages of atherosclerotic lesion development

scientific article

Endogenous glucocorticoids exacerbate cholestasis-associated liver injury and hypercholesterolemia in mice

scientific article published in July 2016

Endosomal Actin Remodeling by Coronin-1A Controls Lipoprotein Uptake and Degradation in Macrophages

article published in 2012

Enhanced foam cell formation, atherosclerotic lesion development, and inflammation by combined deletion of ABCA1 and SR-BI in Bone marrow-derived cells in LDL receptor knockout mice on western-type diet

scientific article published on 11 November 2010

Genetic studies in mice and humans reveal new physiological roles for the high-density lipoprotein receptor scavenger receptor class B type I.

scientific article

HDL cholesterol levels are an important factor for determining the lifespan of erythrocytes

scientific article published in November 2005

HDL is redundant for adrenal steroidogenesis in LDLR knockout mice with a human-like lipoprotein profile

scientific article published on 18 February 2016

HDL particle size is a critical determinant of ABCA1-mediated macrophage cellular cholesterol export

scientific article

HDL scavenger receptor class B type I and platelet function ⬇️

scientific article published on August 1, 2011

Haloperidol inhibits the development of atherosclerotic lesions in LDL receptor knockout mice

scientific article

Hematopoietic arginase 1 deficiency results in decreased leukocytosis and increased foam cell formation but does not affect atherosclerosis

scientific article published on 16 November 2016

Hepatic cell-specific ATP-binding cassette (ABC) transporter profiling identifies putative novel candidates for lipid homeostasis in mice

scientific article published on 28 August 2007

High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-κB/STAT1-IRF1 Signaling

scientific article

High-density lipoprotein as a modulator of platelet and coagulation responses

scientific article published on June 2014

High-density lipoprotein attenuates Th1 and th17 autoimmune responses by modulating dendritic cell maturation and function

scientific article published on 13 April 2015

High-density lipoprotein: key molecule in cholesterol efflux and the prevention of atherosclerosis

scientific article published on May 2010

Human ATP-binding cassette G1 controls macrophage lipoprotein lipase bioavailability and promotes foam cell formation

scientific article

Important role for bone marrow-derived cholesteryl ester transfer protein in lipoprotein cholesterol redistribution and atherosclerotic lesion development in LDL receptor knockout mice

scientific article published on 9 February 2007

Increased oxidative stress in scavenger receptor BI knockout mice with dysfunctional HDL.

scientific article published on 23 August 2007

Independent protective roles for macrophage Abcg1 and Apoe in the atherosclerotic lesion development

scientific article published on 23 January 2009

LCAT deficiency in mice is associated with a diminished adrenal glucocorticoid function

scientific article published on 24 November 2012

Lecithin:cholesterol acyltransferase: old friend or foe in atherosclerosis?

scientific article

Lentiviral shRNA silencing of murine bone marrow cell CCR2 leads to persistent knockdown of CCR2 function in vivo

scientific article published on 10 May 2005

Leucocyte cathepsin K affects atherosclerotic lesion composition and bone mineral density in low-density lipoprotein receptor deficient mice

scientific article published on 17 November 2008

Leukocyte ABCA1 remains atheroprotective in splenectomized LDL receptor knockout mice

scientific article

Lipoproteins as modulators of atherothrombosis: From endothelial function to primary and secondary coagulation

scientific article

Macrophage ABCA5 deficiency influences cellular cholesterol efflux and increases susceptibility to atherosclerosis in female LDLr knockout mice

scientific article

Macrophage ABCG1 deletion disrupts lipid homeostasis in alveolar macrophages and moderately influences atherosclerotic lesion development in LDL receptor-deficient mice

scientific article

Macrophage ATP-binding cassette transporter A1 overexpression inhibits atherosclerotic lesion progression in low-density lipoprotein receptor knockout mice

scientific article published on 2 February 2006

Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice

scientific article

Macrophage phospholipid transfer protein contributes significantly to total plasma phospholipid transfer activity and its deficiency leads to diminished atherosclerotic lesion development

scientific article published on 14 December 2006

Macrophage-specific expression of group IIA sPLA2 results in accelerated atherogenesis by increasing oxidative stress

scientific article published on 16 May 2005

Mouse models of disturbed HDL metabolism

scientific article

Native high-density lipoproteins inhibit platelet activation via scavenger receptor BI: role of negatively charged phospholipids.

scientific article

Orp8 deficiency in bone marrow-derived cells reduces atherosclerotic lesion progression in LDL receptor knockout mice

scientific article

Plasma levels of 27-hydroxycholesterol in humans and mice with monogenic disturbances of high density lipoprotein metabolism ⬇️

scientific article published on 03 November 2010

Plasma lipoproteins are required for both basal and stress-induced adrenal glucocorticoid synthesis and protection against endotoxemia in mice

scientific article published on 21 September 2010

Regulation of cholesterol homeostasis in macrophages and consequences for atherosclerotic lesion development

scientific article

Relative roles of various efflux pathways in net cholesterol efflux from macrophage foam cells in atherosclerotic lesions

scientific article published on October 2010

Repopulation of apolipoprotein E knockout mice with CCR2-deficient bone marrow progenitor cells does not inhibit ongoing atherosclerotic lesion development

scientific article

Restoration of high-density lipoprotein levels by cholesteryl ester transfer protein expression in scavenger receptor class B type I (SR-BI) knockout mice does not normalize pathologies associated with SR-BI deficiency

scientific article

Role of the macrophage very-low-density lipoprotein receptor in atherosclerotic lesion development

scientific article

Scavenger receptor BI and ATP-binding cassette transporter A1 in reverse cholesterol transport and atherosclerosis

scientific article

Scavenger receptor BI facilitates the metabolism of VLDL lipoproteins in vivo

scientific article published on 22 October 2007

Scavenger receptor BI plays a role in facilitating chylomicron metabolism

scientific article published on 17 February 2004

Scavenger receptor BI: a multi-purpose player in cholesterol and steroid metabolism ⬇️

scientific article published on December 21, 2010

Scavenger receptor class B type I-mediated uptake of serum cholesterol is essential for optimal adrenal glucocorticoid production

scientific article published on 28 January 2009

Silencing of Anticoagulant Protein C Evokes Low-Incident but Spontaneous Atherothrombosis in Apolipoprotein E-Deficient Mice-Brief Report

scientific article published on 16 March 2017

Simvastatin treatment aggravates the glucocorticoid insufficiency associated with hypocholesterolemia in mice

scientific article

Specific gene expression of ATP-binding cassette transporters and nuclear hormone receptors in rat liver parenchymal, endothelial, and Kupffer cells

scientific article published on 18 April 2003

Stage-specific remodeling of atherosclerotic lesions upon cholesterol lowering in LDL receptor knockout mice

scientific article

Stimulation of cholesterol efflux by LXR agonists in cholesterol-loaded human macrophages is ABCA1-dependent but ABCG1-independent

scientific article published on 3 September 2009

The expression level of non-alcoholic fatty liver disease-related gene PNPLA3 in hepatocytes is highly influenced by hepatic lipid status

scientific article published on 24 November 2009

The liver-selective thyromimetic T-0681 influences reverse cholesterol transport and atherosclerosis development in mice

scientific article

The presence of leukocyte CC-chemokine receptor 2 in CCR2 knockout mice promotes atherogenesis

scientific article published on 29 October 2004

Transplantation of monocyte CC-chemokine receptor 2-deficient bone marrow into ApoE3-Leiden mice inhibits atherogenesis

scientific article

USF1 deficiency activates brown adipose tissue and improves cardiometabolic health

scientific article

List of works by

ABCG1 is involved in vitamin E efflux

ATP-binding cassette transporter A1 in lipoprotein metabolism and atherosclerosis: a new piece of the complex puzzle

ATP-binding cassette transporter A1: key player in cardiovascular and metabolic disease at local and systemic level

ATP-binding cassette transporters A1 and G1, HDL metabolism, cholesterol efflux, and inflammation: important targets for the treatment of atherosclerosis

Abca1 deficiency protects the heart against myocardial infarction-induced injury

Absence of HDL cholesteryl ester uptake in mice via SR-BI impairs an adequate adrenal glucocorticoid-mediated stress response to fasting

Activation of human platelets by misfolded proteins

Activation of the nuclear receptor PXR decreases plasma LDL-cholesterol levels and induces hepatic steatosis in LDL receptor knockout mice

Adenovirus-mediated hepatic overexpression of scavenger receptor class B type I accelerates chylomicron metabolism in C57BL/6J mice

Adrenal-specific scavenger receptor BI deficiency induces glucocorticoid insufficiency and lowers plasma very-low-density and low-density lipoprotein levels in mice

Adrenocortical LDL receptor function negatively influences glucocorticoid output

Aorta of ApoE-deficient mice responds to atherogenic stimuli by a prelesional increase and subsequent decrease in the expression of antioxidant enzymes

Augmented atherogenesis in LDL receptor deficient mice lacking both macrophage ABCA1 and ApoE

Bone marrow-derived multidrug resistance protein ABCB4 protects against atherosclerotic lesion development in LDL receptor knockout mice

Both hepatic and extrahepatic ABCA1 have discrete and essential functions in the maintenance of plasma high-density lipoprotein cholesterol levels in vivo

Coexistence of foam cells and hypocholesterolemia in mice lacking the ABC transporters A1 and G1.

Combined deletion of macrophage ABCA1 and ABCG1 leads to massive lipid accumulation in tissue macrophages and distinct atherosclerosis at relatively low plasma cholesterol levels

Correction: Effects of Deletion of Macrophage ABCA7 on Lipid Metabolism and the Development of Atherosclerosis in the Presence and Absence of ABCA1.

Cyclosporin A decreases apolipoprotein E secretion from human macrophages via a protein phosphatase 2B-dependent and ATP-binding cassette transporter A1 (ABCA1)-independent pathway

Deletion of the high-density lipoprotein receptor scavenger receptor BI in mice modulates thrombosis susceptibility and indirectly affects platelet function by elevation of plasma free cholesterol

Diet induced regulation of genes involved in cholesterol metabolism in rat liver parenchymal and Kupffer cells

Differential effects of scavenger receptor BI deficiency on lipid metabolism in cells of the arterial wall and in the liver

Downregulation of platelet responsiveness upon contact with LDL by the protein-tyrosine phosphatases SHP-1 and SHP-2.

Dual role for scavenger receptor class B, type I on bone marrow-derived cells in atherosclerotic lesion development

Effects of deletion of macrophage ABCA7 on lipid metabolism and the development of atherosclerosis in the presence and absence of ABCA1

Elimination of macrophages drives LXR-induced regression both in initial and advanced stages of atherosclerotic lesion development

Endogenous glucocorticoids exacerbate cholestasis-associated liver injury and hypercholesterolemia in mice

Endosomal Actin Remodeling by Coronin-1A Controls Lipoprotein Uptake and Degradation in Macrophages

Enhanced foam cell formation, atherosclerotic lesion development, and inflammation by combined deletion of ABCA1 and SR-BI in Bone marrow-derived cells in LDL receptor knockout mice on western-type diet

Genetic studies in mice and humans reveal new physiological roles for the high-density lipoprotein receptor scavenger receptor class B type I.

HDL cholesterol levels are an important factor for determining the lifespan of erythrocytes

HDL is redundant for adrenal steroidogenesis in LDLR knockout mice with a human-like lipoprotein profile

HDL particle size is a critical determinant of ABCA1-mediated macrophage cellular cholesterol export

HDL scavenger receptor class B type I and platelet function ⬇️

Haloperidol inhibits the development of atherosclerotic lesions in LDL receptor knockout mice

Hematopoietic arginase 1 deficiency results in decreased leukocytosis and increased foam cell formation but does not affect atherosclerosis

Hepatic cell-specific ATP-binding cassette (ABC) transporter profiling identifies putative novel candidates for lipid homeostasis in mice

High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-κB/STAT1-IRF1 Signaling

High-density lipoprotein as a modulator of platelet and coagulation responses

High-density lipoprotein attenuates Th1 and th17 autoimmune responses by modulating dendritic cell maturation and function

High-density lipoprotein: key molecule in cholesterol efflux and the prevention of atherosclerosis

Human ATP-binding cassette G1 controls macrophage lipoprotein lipase bioavailability and promotes foam cell formation

Important role for bone marrow-derived cholesteryl ester transfer protein in lipoprotein cholesterol redistribution and atherosclerotic lesion development in LDL receptor knockout mice

Increased oxidative stress in scavenger receptor BI knockout mice with dysfunctional HDL.

Independent protective roles for macrophage Abcg1 and Apoe in the atherosclerotic lesion development

LCAT deficiency in mice is associated with a diminished adrenal glucocorticoid function

Lecithin:cholesterol acyltransferase: old friend or foe in atherosclerosis?

Lentiviral shRNA silencing of murine bone marrow cell CCR2 leads to persistent knockdown of CCR2 function in vivo

Leucocyte cathepsin K affects atherosclerotic lesion composition and bone mineral density in low-density lipoprotein receptor deficient mice

Leukocyte ABCA1 remains atheroprotective in splenectomized LDL receptor knockout mice

Lipoproteins as modulators of atherothrombosis: From endothelial function to primary and secondary coagulation

Macrophage ABCA5 deficiency influences cellular cholesterol efflux and increases susceptibility to atherosclerosis in female LDLr knockout mice

Macrophage ABCG1 deletion disrupts lipid homeostasis in alveolar macrophages and moderately influences atherosclerotic lesion development in LDL receptor-deficient mice

Macrophage ATP-binding cassette transporter A1 overexpression inhibits atherosclerotic lesion progression in low-density lipoprotein receptor knockout mice

Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice

Macrophage phospholipid transfer protein contributes significantly to total plasma phospholipid transfer activity and its deficiency leads to diminished atherosclerotic lesion development

Macrophage-specific expression of group IIA sPLA2 results in accelerated atherogenesis by increasing oxidative stress

Mouse models of disturbed HDL metabolism

Native high-density lipoproteins inhibit platelet activation via scavenger receptor BI: role of negatively charged phospholipids.

Orp8 deficiency in bone marrow-derived cells reduces atherosclerotic lesion progression in LDL receptor knockout mice

Plasma levels of 27-hydroxycholesterol in humans and mice with monogenic disturbances of high density lipoprotein metabolism ⬇️

Plasma lipoproteins are required for both basal and stress-induced adrenal glucocorticoid synthesis and protection against endotoxemia in mice

Regulation of cholesterol homeostasis in macrophages and consequences for atherosclerotic lesion development

Relative roles of various efflux pathways in net cholesterol efflux from macrophage foam cells in atherosclerotic lesions

Repopulation of apolipoprotein E knockout mice with CCR2-deficient bone marrow progenitor cells does not inhibit ongoing atherosclerotic lesion development

Restoration of high-density lipoprotein levels by cholesteryl ester transfer protein expression in scavenger receptor class B type I (SR-BI) knockout mice does not normalize pathologies associated with SR-BI deficiency

Role of the macrophage very-low-density lipoprotein receptor in atherosclerotic lesion development

Scavenger receptor BI and ATP-binding cassette transporter A1 in reverse cholesterol transport and atherosclerosis

Scavenger receptor BI facilitates the metabolism of VLDL lipoproteins in vivo

Scavenger receptor BI plays a role in facilitating chylomicron metabolism

Scavenger receptor BI: a multi-purpose player in cholesterol and steroid metabolism ⬇️

Scavenger receptor class B type I-mediated uptake of serum cholesterol is essential for optimal adrenal glucocorticoid production

Silencing of Anticoagulant Protein C Evokes Low-Incident but Spontaneous Atherothrombosis in Apolipoprotein E-Deficient Mice-Brief Report

Simvastatin treatment aggravates the glucocorticoid insufficiency associated with hypocholesterolemia in mice

Specific gene expression of ATP-binding cassette transporters and nuclear hormone receptors in rat liver parenchymal, endothelial, and Kupffer cells

Stage-specific remodeling of atherosclerotic lesions upon cholesterol lowering in LDL receptor knockout mice

Stimulation of cholesterol efflux by LXR agonists in cholesterol-loaded human macrophages is ABCA1-dependent but ABCG1-independent

The expression level of non-alcoholic fatty liver disease-related gene PNPLA3 in hepatocytes is highly influenced by hepatic lipid status

The liver-selective thyromimetic T-0681 influences reverse cholesterol transport and atherosclerosis development in mice