Search filters

List of works by Sergio A Quezada

A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer

scientific article published on 30 January 2017

A highly compact epitope-based marker/suicide gene for easier and safer T-cell therapy

scientific article published on 26 June 2014

ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation

scientific article published on 01 July 2018

An antitumor boost to TH9 cells

scientific article published on 01 August 2014

Analysis of the underlying cellular mechanisms of anti-CD154-induced graft tolerance: the interplay of clonal anergy and immune regulation

scientific article published in July 2005

Anti-programmed cell death-1 therapy and insulin-dependent diabetes: a case report

scientific article published on April 2015

Author Correction: Pan-cancer deconvolution of tumour composition using DNA methylation

scientific article published in Nature Communications

Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti-CTLA-4 antibodies

scientific article

CD25-T<sub>reg</sub>-depleting antibodies preserving IL-2 signaling on effector T cells enhance effector activation and antitumor immunity

scientific article published on 09 November 2020

CD40/CD154 interactions at the interface of tolerance and immunity

scientific article published on January 2004

CMV promotes recipient T-cell immunity following reduced-intensity T-cell-depleted HSCT, significantly modulating chimerism status

scientific article published on 12 December 2014

CTLA4 blockade and GM-CSF combination immunotherapy alters the intratumor balance of effector and regulatory T cells

scientific article published on 15 June 2006

Cancer immunotherapy: co-stimulatory agonists and co-inhibitory antagonists.

scientific article published on 18 February 2009

Cell intrinsic mechanisms of T-cell inhibition and application to cancer therapy

scientific article published on August 2008

Chromatin regulation and immune escape

scientific article published in February 2018

Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade

scientific article published on 03 March 2016

Consensus on precision medicine for metastatic cancers: a report from the MAP conference.

scientific article published on 3 May 2016

Cord blood T cells mediate enhanced antitumor effects compared with adult peripheral blood T cells.

scientific article published on 8 October 2015

Corrigendum: Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis

scientific article published on 4 April 2017

Corrigendum: Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

scientific article published in Nature

Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism

scientific article

Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity.

scientific article

Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma

scientific article published on 28 October 2021

Distinct mechanisms of action of anti-CD154 in early versus late treatment of murine lupus nephritis

scientific article

Distinctive maturation of in vitro versus in vivo anti-CD40 mAb-matured dendritic cells in mice

article

Engagement of the ICOS pathway markedly enhances efficacy of CTLA-4 blockade in cancer immunotherapy

scientific article published on 31 March 2014

Escape from nonsense-mediated decay associates with anti-tumor immunogenicity

scientific article published on 30 July 2020

Evolving adoptive cellular therapies in urological malignancies

scientific article published on June 2017

Expansion of airway basal epithelial cells from primary human non-small cell lung cancer tumors

scientific article published on 22 March 2018

Exploiting CTLA-4, PD-1 and PD-L1 to reactivate the host immune response against cancer.

scientific article published on 19 March 2013

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.

scientific article

Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors

scientific article

Fc-dependent depletion of tumor-infiltrating regulatory T cells co-defines the efficacy of anti-CTLA-4 therapy against melanoma

scientific article

Fcγ-receptor tag team boosts anti-tumor immunity

scientific article published on 16 June 2015

Geospatial immune variability illuminates differential evolution of lung adenocarcinoma

scientific article published on 27 May 2020

Immunomodulatory antibodies for the treatment of lymphoma: Report on the CALYM Workshop

scientific article published on 19 May 2016

Impact of tumour microenvironment and Fc receptors on the activity of immunomodulatory antibodies

scientific article

Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis

scientific article published on 07 July 2017

Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis

scientific article published on 16 December 2016

Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma

scientific article published on 19 January 2021

Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters

scientific article published in October 2017

Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade. ⬇️

scientific article published in January 2018

Ipilimumab: attenuation of an inhibitory immune checkpoint improves survival in metastatic melanoma

scientific article

Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes.

scientific article published on 29 August 2016

Limited tumor infiltration by activated T effector cells restricts the therapeutic activity of regulatory T cell depletion against established melanoma

scientific article published on 25 August 2008

Mechanisms of donor-specific transfusion tolerance: preemptive induction of clonal T-cell exhaustion via indirect presentation

scientific article published on 15 May 2003

Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition

scientific article published on 27 January 2021

Negative immune checkpoints on T lymphocytes and their relevance to cancer immunotherapy

scientific article published on 26 October 2015

Neoantigen heterogeneity: a key driver of immune response and sensitivity to immune checkpoint blockade?

scientific article

Neoantigen-directed immune escape in lung cancer evolution

scientific article published on 20 March 2019

Oncogenic Transformation Can Orchestrate Immune Evasion and Inflammation in Human Mesenchymal Stem Cells Independently of Extrinsic Immune-Selective Pressure

scientific article

Osimertinib and anti-HER3 combination therapy engages immune dependent tumor toxicity via STING activation in trans

scientific article published on 28 March 2022

PD-1 blockade: promoting endogenous anti-tumor immunity

scientific article published on 01 October 2012

PD-L1 signaling on human memory CD4+ T cells induces a regulatory phenotype

scientific article published on 26 April 2021

Pan-cancer deconvolution of tumour composition using DNA methylation

scientific article published in Nature Communications

Pembrolizumab is effective for drug-resistant gestational trophoblastic neoplasia.

scientific article published in November 2017

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

scientific article

Principles and use of anti-CTLA4 antibody in human cancer immunotherapy

scientific article

Publisher Correction: Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer

scientific article published on 03 June 2020

RORγt+ Innate Lymphoid Cells Promote Lymph Node Metastasis of Breast Cancers

scientific article published on 12 January 2017

Regulation of CD4 T cell activation and effector function by inducible costimulator (ICOS).

scientific article published on 29 January 2010

Resolution of acute inflammation bridges the gap between innate and adaptive immunity

scientific article published on 8 July 2014

Shifting the equilibrium in cancer immunoediting: from tumor tolerance to eradication

scientific article published on May 2011

Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer

scientific article published on 07 October 2019

TALEN-Mediated Inactivation of PD-1 in Tumor-Reactive Lymphocytes Promotes Intratumoral T-cell Persistence and Rejection of Established Tumors

scientific article published on April 2016

TALEN-mediated genetic inactivation of the glucocorticoid receptor in cytomegalovirus-specific T cells

scientific article

The "Achilles Heel" of Cancer and Its Implications for the Development of Novel Immunotherapeutic Strategies.

scientific article

The Balance Between Donor T Cell Anergy and Suppression Versus Lethal Graft-Versus-Host Disease Is Determined by Host Conditioning

scientific article published on 01 November 2002

The Heterogeneity of Ly6Chi Monocytes Controls Their Differentiation into iNOS+ Macrophages or Monocyte-Derived Dendritic Cells

scientific article published on December 2016

The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2.

scientific article published on February 2017

The function and dysfunction of memory CD8+ T cells in tumor immunity

scientific article published on 01 May 2018

Tissue-resident memory CD8+ T cells amplify anti-tumor immunity by triggering antigen spreading through dendritic cells

scientific article published on 27 September 2019

Too Much of a Good Thing? Chronic IFN Fuels Resistance to Cancer Immunotherapy

scientific article published in December 2016

Tracking genomic cancer evolution for precision medicine: the lung TRACERx study

scientific article

Tracking the Evolution of Non-Small-Cell Lung Cancer

scientific article published on 26 April 2017

Translational implications of tumor heterogeneity

scientific article

Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts

scientific article

Tumor-reactive CD4+T cells: plasticity beyond helper and regulatory activities

scientific article published on 01 August 2011

Tumour heterogeneity and immune-modulation

scientific article published on 07 May 2013

Ultra-deep T cell receptor sequencing reveals the complexity and intratumour heterogeneity of T cell clones in renal cell carcinomas

scientific article

Urine-derived lymphocytes as a non-invasive measure of the bladder tumor immune microenvironment

scientific article published on 26 September 2018

Virulent Salmonella enterica serovar typhimurium evades adaptive immunity by preventing dendritic cells from activating T cells

scientific article published on November 2006

Paulina is supported by:

About Paulina

Help