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List of works by Anna Philpott

An oncologist׳s friend: How Xenopus contributes to cancer research

scientific article

Ascl1 phospho-status regulates neuronal differentiation in a Xenopus developmental model of neuroblastoma

scientific article published on 18 March 2015

Assessing Ubiquitylation of Individual Proteins Using Xenopus Extract Systems

scientific article published on 03 June 2019

Calculating the Degradation Rate of Individual Proteins Using Xenopus Extract Systems

scientific article published on 03 June 2019

Cell cycle regulation of proliferation versus differentiation in the central nervous system.

scientific article published on 25 May 2014

Cell cycle-dependent phosphorylation and regulation of cellular differentiation

scientific article published on 20 September 2018

Cell cycle-regulated multi-site phosphorylation of Neurogenin 2 coordinates cell cycling with differentiation during neurogenesis

scientific article

Cell cycling and differentiation do not require the retinoblastoma protein during early Xenopus development.

scientific article published on 11 November 2006

Co-ordination of cell cycle and differentiation in the developing nervous system ⬇️

scientific article published on June 15, 2012

Complex domain interactions regulate stability and activity of closely related proneural transcription factors.

scientific article published on 3 July 2014

Complex regulation controls Neurogenin3 proteolysis.

scientific article

Defining Lineage Potential and Fate Behavior of Precursors during Pancreas Development

article

Dephosphorylation of the proneural transcription factor ASCL1 re-engages a latent post-mitotic differentiation programme in neuroblastoma

scientific article published on 12 October 2020

Emergence of neuronal diversity from patterning of telencephalic progenitors.

scientific article

G1/S phase cyclin-dependent kinase overexpression perturbs early development and delays tissue-specific differentiation in Xenopus.

scientific article

Hes6 is required for the neurogenic activity of neurogenin and NeuroD

scientific article

Interaction between opposing modes of phospho-regulation of the proneural proteins Ascl1 and Ngn2

scientific article published on 01 October 2018

Lineage selection and plasticity in the intestinal crypt

scientific article

Models of Cancer: Expanding the Oncologist's Toolbox

scientific article published on 27 November 2018

Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation.

scientific article published on 26 April 2017

Multi-site phospho-regulation of proneural transcription factors controls proliferation versus differentiation in development and reprogramming.

scientific article

Multi-site phosphorylation regulates NeuroD4 activity during primary neurogenesis: a conserved mechanism amongst proneural proteins

scientific article published on 18 June 2015

MyoD phosphorylation on multiple C terminal sites regulates myogenic conversion activity.

scientific article published on 4 November 2016

Nervous decision-making: to divide or differentiate

scientific article published on 30 April 2014

Neuroblastoma progress on many fronts: the Neuroblastoma Research Symposium ⬇️

scientific article published on September 15, 2011

Neurogenin3 phosphorylation controls reprogramming efficiency of pancreatic ductal organoids into endocrine cells

scientific article published in Scientific Reports

New Insights Into the Role of Ubiquitylation of Proteins.

scientific article published on 8 March 2016

Non-canonical ubiquitylation of the proneural protein Ngn2 occurs in both Xenopus embryos and mammalian cells.

scientific article

Non-canonical ubiquitylation: mechanisms and consequences.

scientific article

Phospho-regulation of ATOH1 Is Required for Plasticity of Secretory Progenitors and Tissue Regeneration

scientific article published on 09 August 2018

Post-translational modification of Ngn2 differentially affects transcription of distinct targets to regulate the balance between progenitor maintenance and differentiation.

scientific article published on 4 April 2012

Regulation of cell fate determination by Skp1-Cullin1-F-box (SCF) E3 ubiquitin ligases.

scientific article published on January 2011

Regulation of neurogenin stability by ubiquitin-mediated proteolysis.

scientific article

Subcellular localisation modulates ubiquitylation and degradation of Ascl1.

scientific article published on 15 March 2018

The E3 ubiquitin ligase skp2 regulates neural differentiation independent from the cell cycle.

scientific article

The F-box protein Cdc4/Fbxw7 is a novel regulator of neural crest development in Xenopus laevis

scientific article

The N terminus of Ascl1 underlies differing proneural activity of mouse and Ascl1 proteins

scientific article published on 26 September 2018

The Xenopus cell cycle: an overview

scientific article published on 12 February 2008

The developmental origin of brain tumours: a cellular and molecular framework.

scientific article

The phosphorylation status of Ascl1 is a key determinant of neuronal differentiation and maturation in vivo and in vitro

scientific article published on 12 May 2014

The role of nucleoplasmin in chromatin assembly and disassembly

scientific article

Tracing the cellular basis of islet specification in mouse pancreas

scientific article published on 07 October 2020

Ubiquitin-mediated proteolysis in Xenopus extract.

scientific article published on 16 August 2016

Universality of clone dynamics during tissue development

article

p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex

scientific article

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