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List of works by Waseem Qasim

"Darwinian" tumor-suppression model unsupported in clinical experience

scientific article published on September 2014

'Mini' U6 Pol III promoter exhibits nucleosome redundancy and supports multiplexed coupling of CRISPR/Cas9 effects

scientific article published on 20 March 2020

22q11.2 Deletion Syndrome with Life-Threatening Adenovirus Infection

A double cure: Omenn syndrome and β thalassaemia successfully treated with mismatched unrelated donor transplantation

scientific article published on 23 May 2011

Abnormal expression of only the CD34 part of a transgenic CD34/herpes simplex virus-thymidine kinase fusion protein is associated with ganciclovir resistance

scientific article

Adoptive T-cell therapy for cancer in the United kingdom: a review of activity for the British Society of Gene and Cell Therapy annual meeting 2015.

scientific article published on May 2015

Allogeneic CAR T cell therapies for leukemia - R1

scientific article published on 01 February 2019

Allogeneic hematopoietic stem-cell transplantation for leukocyte adhesion deficiency

scientific article (publication date: March 2009)

Alternative donor SCT for the treatment of MHC class II deficiency.

scientific article published on 24 September 2012

Anticardiolipin antibodies and thromboembolism after BMT.

scientific article published in April 1998

Astrovirus VA1/HMO-C: an increasingly recognized neurotropic pathogen in immunocompromised patients

scientific article

Autologous Transplantation of Amniotic Fluid-Derived Mesenchymal Stem Cells into Sheep Fetuses

scientific article published in March 2016

Autologous transplantation of amniotic fluid-derived mesenchymal stem cells into sheep fetuses

scientific article published on 19 November 2010

Automated manufacturing of chimeric antigen receptor T cells for adoptive immunotherapy using CliniMACS prodigy

scientific article published on August 2016

Base-edited CAR T Cells for combinational therapy against T cell malignancies

Base-edited CAR T cells for combinational therapy against T cell malignancies

scientific article published on 25 May 2021

Capture and generation of adenovirus specific T cells for adoptive immunotherapy

scientific article published on 8 November 2006

Cell-specific and efficient expression in mouse and human B cells by a novel hybrid immunoglobulin promoter in a lentiviral vector.

scientific article published on 13 September 2007

Clinical and immunologic outcome of patients with cartilage hair hypoplasia after hematopoietic stem cell transplantation.

scientific article

Clinical and immunological manifestations of patients with atypical severe combined immunodeficiency.

scientific article published on 30 May 2011

Comparison of lentiviral and sleeping beauty mediated αβ T cell receptor gene transfer

scientific article

Cord blood T cells mediate enhanced antitumor effects compared with adult peripheral blood T cells.

scientific article published on 8 October 2015

Cord blood transplantation recapitulates fetal ontogeny with a distinct molecular signature that supports CD4 T-cell reconstitution

scientific article published on 02 November 2017

Deep sequencing reveals persistence of cell-associated mumps vaccine virus in chronic encephalitis.

scientific article published on 21 October 2016

Effect of stem cell source on long-term chimerism and event-free survival in children with primary immunodeficiency disorders after fludarabine and melphalan conditioning regimen

scientific article

Elimination of human leukemia cells in NOD/SCID mice by WT1-TCR gene-transduced human T cells

scientific article published on 14 July 2005

Emerging applications of gene edited T cells for the treatment of leukemia

scientific article published on 4 July 2017

Engineered T cell therapies

scientific article

Ex-vivo gene therapy restores LEKTI activity and corrects the architecture of Netherton syndrome-derived skin grafts

scientific article

FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency

scientific article published on 03 December 2021

FOXRED1, encoding an FAD-dependent oxidoreductase complex-I-specific molecular chaperone, is mutated in infantile-onset mitochondrial encephalopathy

scientific article

FOXRED1, encoding an FAD-dependent oxidoreductase complex-I-specific molecular chaperone, is mutated in infantile-onset mitochondrial encephalopathy

scientific article published on 28 May 2015

Frequent occurrence of cytomegalovirus retinitis during immune reconstitution warrants regular ophthalmic screening in high-risk pediatric allogeneic hematopoietic stem cell transplant recipients

scientific article published on 3 April 2014

Gene Modified T Cell Therapies for Hematological Malignancies

scientific article published in October 2017

Gene therapies for inherited skin disorders

scientific article published on June 2014

Gene therapy for primary immunodeficiencies: current status and future prospects

scientific article published on June 2014

Gene therapy for severe combined immune deficiency

scientific article published on 2 July 2004

Gene therapy strategies to exploit TRIM derived restriction factors against HIV-1.

scientific article published on 14 January 2014

Generation and Clinical Application of Gene-Modified Autologous Epidermal Sheets in Netherton Syndrome: Lessons Learned from a Phase 1 Trial

scientific article published on 05 August 2019

Genome-Edited T Cell Therapies.

scientific article

Hematopoietic stem cell transplantation for cytidine triphosphate synthase 1 (CTPS1) deficiency

scientific article published on 08 June 2018

Hematopoietic stem cell transplantation in 29 patients hemizygous for hypomorphic IKBKG / NEMO mutations.

scientific article published on 5 July 2017

Host natural killer immunity is a key indicator of permissiveness for donor cell engraftment in patients with severe combined immunodeficiency

scientific article

How I treat severe combined immunodeficiency

scientific article published on 10 October 2013

Human Coronavirus OC43 Associated with Fatal Encephalitis

scientific article published in August 2016

Human Mesenchymal Stromal Cells Engineered to Express Collagen VII Can Restore Anchoring Fibrils in Recessive Dystrophic Epidermolysis Bullosa Skin Graft Chimeras

scientific article published on 19 July 2019

Human involucrin promoter mediates repression-resistant and compartment-specific LEKTI expression

scientific article published on January 2012

Hybrid lentiviral vectors

scientific article published on 20 April 2010

Identifying functional defects in patients with immune dysregulation due to LRBA and CTLA-4 mutations.

scientific article published on 3 February 2017

Immune reconstitution and recovery of FOXP3 (forkhead box P3)-expressing T cells after transplantation for IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked) syndrome.

scientific article

Immune reconstitution following hematopoietic stem cell transplantation using different stem cell sources

scientific article published on 09 May 2019

Immunotherapy of HCC metastases with autologous T cell receptor redirected T cells, targeting HBsAg in a liver transplant patient

scientific article published on 13 October 2014

Impact of viral reactivations in the era of pre-emptive antiviral drug therapy following allogeneic haematopoietic SCT in paediatric recipients ⬇️

scientific article published on November 26, 2012

Impaired EIF2S3 function associated with a novel phenotype of X-linked hypopituitarism with glucose dysregulation

scientific article published on 14 March 2019

Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency

scientific article published on 17 April 2017

Interferon-γ capture T cell therapy for persistent Adenoviraemia following allogeneic haematopoietic stem cell transplantation

scientific article published on 22 February 2013

Lentiviral Engineered Fibroblasts Expressing Codon-Optimized COL7A1 Restore Anchoring Fibrils in RDEB.

scientific article published on January 2016

Lentiviral gene therapy against human immunodeficiency virus type 1, using a novel human TRIM21-cyclophilin A restriction factor.

scientific article

Lentiviral vectors for T-cell suicide gene therapy: preservation of T-cell effector function after cytokine-mediated transduction

scientific article published in February 2007

Long Terminal Repeat CRISPR-CAR-Coupled "Universal" T Cells Mediate Potent Anti-leukemic Effects

scientific article published on 6 March 2018

Long-term outcome and lineage-specific chimerism in 194 patients with Wiskott-Aldrich syndrome treated by hematopoietic cell transplantation in the period 1980-2009: an international collaborative study

scientific article

Management of adenovirus in children after allogeneic hematopoietic stem cell transplantation

scientific article published on 28 October 2013

Manufacture of GMP-compliant functional adenovirus-specific T-cell therapy for treatment of post-transplant infectious complications

scientific article published on 13 July 2016

Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells

scientific article published in January 2017

Multicenter phase 1/2 application of adenovirus-specific T cells in high-risk pediatric patients after allogeneic stem cell transplantation.

scientific article

Mutations in linker for activation of T cells (LAT) lead to a novel form of severe combined immunodeficiency

scientific article published on 15 July 2016

New graft manipulation strategies improve the outcome of mismatched stem cell transplantation in children with primary immunodeficiencies

scientific article published on 04 February 2019

Non-posttransplant lymphoproliferative disorder malignancy after hematopoietic stem cell transplantation in patients with primary immunodeficiency: UK experience

scientific article published on 07 March 2018

Novel lentiviral vectors with mutated reverse transcriptase for mRNA delivery of TALE nucleases

scientific article

Omission of in vivo T-cell depletion promotes rapid expansion of naïve CD4+ cord blood lymphocytes and restores adaptive immunity within 2 months after unrelated cord blood transplant

scientific article published on 09 January 2012

One hundred percent survival after transplantation of 34 patients with Wiskott-Aldrich syndrome over 20 years

scientific article published on 25 July 2018

Peanut allergy transferred by BMT

scientific article published on 28 April 2014

Phase I study protocol for ex vivo lentiviral gene therapy for the inherited skin disease, Netherton syndrome

scientific article published on December 2013

Phase I study protocol for ex-vivo lentiviral gene therapy for the inherited skin disease, Netherton Syndrome

scientific article published on 18 October 2013

Production and first-in-man use of T cells engineered to express a HSVTK-CD34 sort-suicide gene

scientific article

Progress and prospects for engineered T cell therapies

scientific article

RISC control for gene therapy

scientific article published in June 2006

Reply to: "To target or not to target viral antigens in HBV related HCC?".

scientific article published on 21 February 2015

Safety and early efficacy outcomes for lentiviral fibroblast gene therapy in recessive dystrophic epidermolysis bullosa

scientific article published on 06 June 2019

Signal transducer and activator of transcription 2 deficiency is a novel disorder of mitochondrial fission

scientific journal article

Sleeping beauty transposition from nonintegrating lentivirus

scientific article

Superantigen scalded skin syndromes

scientific article published on 01 September 1998

T cell receptor-therapy in HBV-related hepatocellularcarcinoma

scientific article published on 19 March 2015

T cell transduction and suicide with an enhanced mutant thymidine kinase.

scientific article

T-cell receptor αβ+ and CD19+ cell-depleted haploidentical and mismatched hematopoietic stem cell transplantation in primary immune deficiency.

scientific article published on 2 August 2017

TCRαβ/CD3 disruption enables CD3-specific antileukemic T cell immunotherapy

The impact of retroviral suicide gene transduction procedures on T cells

scientific article published in November 2003

Third-party virus-specific T cells eradicate adenoviraemia but trigger bystander graft-versus-host disease

scientific article published on 19 April 2011

Treosulfan and Fludarabine Conditioning for Hematopoietic Stem Cell Transplantation in Children with Primary Immunodeficiency: UK Experience.

scientific article published on 16 November 2017

Treosulfan-based conditioning regimens for hematopoietic stem cell transplantation in children with primary immunodeficiency: United Kingdom experience

scholarly article by Mary A Slatter published in April 2011

Umbilical cord blood transplantation without in vivo T-cell depletion for children with MHC class II deficiency

scientific article published on 20 January 2018

Update on clinical gene therapy in childhood

scientific article published on November 2007

Variable phenotype of severe immunodeficiencies associated with RMRP gene mutations.

scientific article

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