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List of works by Lars Wortmann

Damage Incorporated: Discovery of the Potent, Highly Selective, Orally Available ATR Inhibitor BAY 1895344 with Favorable Pharmacokinetic Properties and Promising Efficacy in Monotherapy and in Combination Treatments in Preclinical Tumor Models

scientific article published on 05 June 2020

Discovery and Characterization of the Potent and Highly Selective (Piperidin-4-yl)pyrido[3,2- d]pyrimidine Based in Vitro Probe BAY-885 for the Kinase ERK5

scientific article published on 09 January 2019

Discovery of BAY-298 and BAY-899: Tetrahydro-1,6-naphthyridine-Based, Potent, and Selective Antagonists of the Luteinizing Hormone Receptor Which Reduce Sex Hormone Levels in Vivo

scientific article published on 13 November 2019

Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction

article published in the Proceedings of the National Academy of Sciences of the United States of America

Latest Advances Towards Ras Inhibition: A Medicinal Chemistry Perspective.

scientific article published on 16 September 2016

Mild and Efficient Synthesis of Benzo-Fused Seven- and Eight-membered Ring Lactams: A Convenient Approach to Biologically Interesting Chemotypes

article

Novel and efficient copper-catalysed synthesis of nitrogen-linked medium-ring biaryls.

scientific article published on 2 February 2011

Recovery of carbonyl compounds from N,N-dialkylhydrazones

scientific article published on 01 March 2000

The Novel ATR Inhibitor BAY 1895344 Is Efficacious as Monotherapy and Combined with DNA Damage-Inducing or Repair-Compromising Therapies in Preclinical Cancer Models

scientific article published on 03 October 2019

Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis

scientific article

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